1. History, Epidemiology and Prevention of Burns .................................................................................................. 3 Ravi Chittoria 2. Anatomy of the Skin ............................................................................................................................................ 18 Sujata Sarabahi 3. Burns: Etiology and Classification ...................................................................................................................... 25 Sameek Bhattacharya 4. Pathophysiology of Burn Shock ........................................................................................................................... 37 Arvind Vartak 5. Pathophysiology of Burn Wound ......................................................................................................................... 42 Arvind Vartak 6. Wound Healing in Burns ...................................................................................................................................... 51 Mary Babu, N Shanmuganathan, B Karthikeya Prabhu 7. Immunological Responses to Burn Injury ......................................................................................................... 69 Shankar Sriniwasan 8. The Immunobiology of Skin Transplant Rejection and Acceptance ............................................................... 73 Rakesh Kain 9. Microbiology in Burns ........................................................................................................................................... 79 Deepthi Nair SECTION 2: Early Care in Burns 10. Initial Evaluation and Resuscitation of Burn Patient ..................................................................................... 101 Madhuri A Gore 11. Respiratory Tract Injury in Burns .................................................................................................................... 127 JC Suri, MK Sen 12. Fluid, Electrolyte and Acid-base Disturbances in Burns ................................................................................ 137 Sujata Sarabahi 13. Acute Renal Failure in Burns and its Management ...................................................................................... 142 Rajiv Kohli, Arun Goel SECTION 3: Local Care of Burn Wound 14. Burn Wound Management ................................................................................................................................. 153 Sujata Sarabahi 15. Surgical Excision of Burn Wound and Skin Grafting ..................................................................................... 196 Pramod Kumar 16. Anesthesia for the Thermally Injured.............................................................................................................. 208 PK Verma 17. Biological Dressings and Skin Substitutes in Burns ...................................................................................... 223 PK Bilwani, Deepak Nanda 18. Skin Banking ....................................................................................................................................................... 231 Sujata Sarabahi, Deepak Nanda 19. Keratinocyte Culture .......................................................................................................................................... 235 RP Narayan xvi Principles and Practice of Burn Care