Ferozsons Laboratories Limited

Point # 22:
HVAC System Brief Description
 HVAC (Heating, Ventilation, and Air Conditioning) System has installed in Production

Manufacturing Area.

 It is Malaysian Made system.

 It consists of cooling, heating, blowing sections.

 It has equipped with three different types of filters which support to HVAC System as it

throws clean and filtered air to Production Manufacturing Area, are;

o G3 & G4 Filters (Primary Filter) with 80 – 85% efficiency rate.

o F7 & F9 Filters (Secondary Filter) with 90 – 95% efficiency rate.

o H13 Filter (HEPA Filter) with 99.97% efficiency rate.

o H14 Filter (HEPA Filter) with 99.997% efficiency rate.

 HVAC System has also helpful hand to maintain good working conditions inside the

Production Manufacturing Area like temperature, humidity, air renovation cycle, ventilation

and also to maintain differential pressures with regard to adjacent less clean area.

 It has another impact to products that it controls cross-contamination as the Production

Manufacturing Area has built at negative pressure than adjacent Air Locks.
Point # 23:
Water Treatment Plant Brief Description

 Most Drug Product manufacturing and certain cleaning operations require Purified Water.

 In our Production Manufacturing Plant, Double Reverse Osmosis (RO) Plant has installed.

 Double RO Plant is consists of a series of Sand Filter Column, Activated Carbon Column

and then two Softener (Ion Exchange) Columns, then High Pressure Pump No. 1 equipped

with 5 membrane columns and High Pressure Pump No. 2 equipped with 4 membrane

columns and then Ultra Violet Column just before Purified Water Storage Tank.

 The water flows reservoir tank to feed water tank then through the inlet it enters to sand filter

chamber from where major particles (larger than 20 µm) remove with colloidal form.

 After sand filter, water flows into an activated carbon filter, this activated filter removes free

chlorine, turbidity, odor, taste and/or organic materials.

 This hard water is passed through a bed of ion exchange resin which is filled in a pressure

vessel. The ion exchange resin removes calcium and magnesium ions from water thus

making the water soft. The soft water is then directed to the RO unit.

 RO is the removal of ionic, organic and suspended impurities from water by means of a

membrane. The water flows through the semi-permeable reverse osmosis membranes

under sufficient pressure allows passage of purified water while rejecting and concentrating

dissolved and suspended solids. After RO unit, water passes through UV lamp for the killing

of remaining micro-organisms.
 Schematic Water Treatment Flow

Reservoir Tank Sand Column Carbon Column Softener Columns RO Pump 1 Control Panel
with Membranes

Purified Water Storage Tank UV Light Column RO Pump 2 Control Panel

with Membranes
Point # 25:
Brief Description of Air Lock and Positive Negative Pressures
 Production facility is supported by the HVAC system.

 The Production Processing zones have been isolated from corridor through Air Locks.

 There are TWO types of Air Locks have been built to support the processing zones, are;

o Personnel Air Lock (PAL)

o Material Air Lock (MAL)

 Both types of Air Locks have built as Bubble Air Lock pattern and designed at Positive

Differential Pressure with reference to adjacent Production Processing Zones as well as

Production Corridor.

 Air Locks have 30 Pa ± 3 Pa pressure & equipped with H14 Filters.

 Processing Zones have 15 ± 3 Pa pressure & equipped with H13 Filters.