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“Nursing Notes and Community”
Drug Name Dosages Therapeutic Indications Adverse effects Contraindications Nursing considerations
Actions
ciprofloxacin Adults Ciprofloxacin For the GI Hypersensitivity. Assessment
(si proe flox' a Uncomplicated UTIs: 100– promotes treatment of disturbances; Not to be used History: Allergy to
sin) 250 mg PO q 12 hr for 3 breakage of infections headache, concurrently with ciprofloxacin,
Ciloxan, Cipro, days or 500 mg PO daily double- caused by tremor, tizanidine. Avoid norfloxacin or other
Cipro HC Otic, (ER tablets) for 3 days. stranded susceptible confusion, exposure to strong quinolones; renal
Cipro I.V., Cipro Proquin XR—500 mg PO DNA in gram-negative convulsions; sunlight or sun dysfunction; seizures;
XR, Co as a single dose. susceptible bacteria, rashes; joint lamps during lactation
Ciprofloxacin Mild to moderate UTIs: 250 organisms including pain; treatment. Physical: Skin color,
(CAN), Proquin mg PO q 12 hr for 7–14 and inhibits Escherichia coli, phototoxicity. lesions; T; orientation,
XR days or 200 mg IV q 12 hr DNA gyrase, Proteus Transient reflexes, affect;
for 7–14 days. which is mirabilis, increases in mucous membranes,
Pregnancy essential in Klebsiella serum bowel sounds; LFTs,
Category C Complicated UTIs: 500 mg reproduction pneumoniae, creatinine. renal function tests
PO q 12 hr for 7–14 days of bacterial Enterobacter Hematological,
Drug classes or 400 mg IV q 12 hr or DNA. cloacae, Proteus hepatic and Interventions
Antibacterial 1,000 mg (ER tablets) PO vulgaris, Proteus renal Arrange for culture
Fluoroquinolo daily for 7–14 days. rettgeri, disturbances. and sensitivity tests
ne Morganella Vasculitis, before beginning
Chronic bacterial morganii, pseudomembra therapy.
prostatitis: 500 mg PO q Pseudomonas nous colitis and Continue therapy for 2
12 hr for 28 days or 400 aeruginosa, tachycardia. days after signs and
mg IV q 12 hr for 28 days. Citrobacter Phototoxicity. symptoms of infection
freundii, Potentially are gone.
Infectious diarrhea: 500 Staphylococcus Fatal:
mg q 12 hr PO for 5–7 aureus, Anaphylactoid Be aware that Proquin
days. Staphylococcus reaction; XR is not
epidermidis, cardiopulmonar interchangeable with
Anthrax postexposure: 500 group D y arrest. other forms.
mg PO q 12 hr for 60 days streptococci
or 400 mg IV q 12 hr for 60
Ensure that the
days. Treatment of patient swallows ER
uncomplicated tablets whole; do not
Respiratory infections UTIs caused by cut, crush, or chew.
500–750 mg PO q 12 hr or E. coli, K.
400 mg IV q 8–12 hr for 7– pneumoniae as Ensure that patient is
14 days. a one-time dose well hydrated.
in patients at low
Acute sinusitis: 500 mg PO risk of nausea, Give antacids at least
q 12 hr or 400 mg IV q 12 diarrhea 2 hr after dosing.
hr for 10 days. (Proquin XR)
Monitor clinical
Acute uncomplicated Otic: Treatment response; if no
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pyelonephritis: 1,000 mg of acute otitis improvement is seen
ER tablets PO daily for 7– externa or a relapse occurs,
14 days. repeat culture and
Treatment of sensitivity.
Bone, joint, skin infections: chronic bacterial
500–750 mg PO q 12 hr or prostatitis Encourage patient to
400 mg IV q 8–12 hr for 4– complete full course
6 wk. IV: Treatment of of therapy.
nosocomial
Nosocomial pneumonia: pneumonia Teaching points
400 mg IV q 8 hr for 10–14 caused by If an antacid is
days. Haemophilus needed, take it at
influenza, K. least 2 hours before
Ophthalmic infections pneumoniae or after dose.
caused by susceptible
Take Proquin XR with
organisms not responsive Oral: Typhoid
the main meal of the
to other therapy: 1 or 2 fever
day.
drops per eye daily or bid
or 1/2 inch ribbon of Oral: STDs
Do not touch tip of
ointment into conjunctival caused by
eye ointment or
sac tid on first 2 days, then Neisseria
solution for this may
apply 1/2 inch ribbon bid gonorrhea
contaminate the
for next 5 days. product.
Prevention of
Acute otitis externa: 4 anthrax following
Drink plenty of fluids
drops in infected ear, tid– exposure to
while you are taking
qid. anthrax bacilla
this drug.
(prophylactic use
Pediatric Patients in regions You may experience
Not recommended; suspected of these side effects:
produced lesions of joint using germ Nausea, vomiting,
cartilage in immature warfare) abdominal pain (eat
experimental animals. frequent small meals);
Acute sinusitis
Inhalational anthrax: 15 diarrhea or
caused by H.
mg/kg/dose PO q 12 hr for constipation;
influenzae,
60 days or 10 mg/kg/dose drowsiness, blurring
Streptococcus
IV q 12 hr for 60 days; do of vision, dizziness
pneumoniae, or
not exceed 500 mg/dose (observe caution if
Moraxella
PO or 400 mg/dose IV. driving or using
catarrhalis
dangerous
Geriatric Patients or equipment).
Lower
Patients with Impaired respiratory tract
Renal Function Report rash, visual
infections:
For creatinine clearance of changes, severe GI
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30–50 mL/min, give 250– Caused by E. problems, weakness,
500 mg PO q 12 hr. For Coli, Klebsiella, tremors.
creatinine clearance of 5– Enterobacter
29 mL/min, give 250–500 species, P.
mg PO q 18 hr or 200–400 mirabilis, P.
mg IV q 18–24 hr. For aeruginosa, H.
patients on hemodialysis, influenzae,
give 250–500 mg q 24 hr, Haemophilia
after dialysis. parainfluenza, S.
pneumoniae
Unlabeled use:
Effective in
patients with
cystic fibrosis
who have
pulmonary
exacerbations