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CIPROFLOXACIN
MECHANISM INDICATION AND ADVERSE NURSING
CLASSIFICATION DOSAGE INSIGHTS
OF ACTION CONTRAINDICATION REACTIONS RESPONSIBILITIES
GENERIC: Inhibits INDICATIONS: DOSAGE AND ROUTE: GI Assessment
CIPRO relaxation of For the treatment of Adults disturbances; History: Allergy to Ciprofloxacin
DNA; inhibits infections caused Uncomplicated UTIs: 100– headache, ciprofloxacin, antibiotics may
BRAND: DNA gyrase by susceptible 250 mg PO q 12 hr for 3 tremor, norfloxacin or other cause serious
Ciproxin, in gram-negative days or 500 mg PO daily confusion, quinolones; renal and possibly
Ciloxan, susceptible bacteria, including (ER tablets) for 3 days. convulsions; dysfunction; seizures; permanent
Cetraxal organisms; Escherichia coli, Proquin XR—500 mg PO rashes; joint lactation. tendon damage
promotes Proteus mirabilis, as a single dose. pain; Physical: Skin color, (such as
PHARMACOLOGI breakage of Klebsiella Mild to moderate UTIs: phototoxicity. lesions; T; tendonitis,
C CLASS: double- pneumoniae, 250 mg PO q 12 hr for 7– Transient orientation, reflexes, tendon rupture),
Fluoroquinolone stranded Enterobacter 14 days or 200 mg IV q 12 increases in affect; mucous nerve problems
s DNA cloacae, Proteus hr for 7–14 days. serum membranes, bowel in the arms and
vulgaris, Proteus Complicated UTIs: 500 mg creatinine. sounds; LFTs, renal legs (peripheral
THERAPEUTIC Inhibits rettgeri, Morganella PO q 12 hr for 7–14 days Hematologic function tests. neuropathy), and
CLASS: enzyme, morganii, or 400 mg IV q 12 hr or al, hepatic nervous system
Antibiotics DNA gyrase, Pseudomonas 1,000 mg (ER tablets) PO and renal Interventions problems.
in aeruginosa, daily for 7–14 days. disturbances. Arrange for culture CIPRO belongs
susceptible Citrobacter freundii, Chronic bacterial Vasculitis, and sensitivity tests to a class of
bacteria, Staphylococcus prostatitis: 500 mg PO q pseudomemb before beginning antibiotics called
interfering aureus, 12 hr for 28 days or 400 ranous colitis therapy. fluoroquinolones.
with bacterial Staphylococcus mg IV q 12 hr for 28 days. and Continue therapy for CIPRO can
cell epidermidis, group Infectious diarrhea: 500 tachycardia. 2 days after signs cause side
replication. D streptococci. mg q 12 hr PO for 5–7 Phototoxicity. and symptoms of effects that may
Treatment of days. infection are gone. be serious or
Therapeutic uncomplicated UTIs Anthrax postexposure: Potentially Be aware that even cause
Effect: caused by E. coli, 500 mg PO q 12 hr for 60 Fatal: Proquin XR is not death. If you get
Bactericidal. K. pneumoniae as a days or 400 mg IV q 12 hr Anaphylactoi interchangeable with any of the
one-time dose in for 60 days. Respiratory d reaction; other forms. following serious
patients at low risk infections 500–750 mg PO cardiopulmon Ensure that the side effects, get
of nausea, diarrhea q 12 hr or 400 mg IV q 8– ary arrest. patient swallows ER medical help
(Proquin XR). 12 hr for 7– 14 days. tablets whole; do not right away. Talk
Source: Otic: Treatment of Acute sinusitis: 500 mg cut, crush, or chew. with your
acute otitis externa PO q 12 hr or 400 mg IV q PREGNANCY- Ensure that patient is healthcare
https:// Treatment of 12 hr for 10 days. LACTATION- well hydrated. provider about
reference chronic bacterial Acute uncomplicated REPRODUCTI Give antacids at least whether you
.medsca prostatitis pyelonephritis: 1,000 mg ON 2 hr after dosing. should continue
pe.com/ IV: Treatment of ER tablets PO daily for 7– Ciprofloxacin Monitor clinical to take CIPRO.
drug/ nosocomial 14 days. may cause response; if no
cipro-xr- pneumonia caused Bone, joint, skin infections: intestinal improvement is seen
ciprofloxa by Haemophilus 500–750 mg PO q 12 hr or flora or a relapse occurs,
cin- influenza, K. 400 mg IV q 8–12 hr for 4– alteration of repeat culture and
342530# pneumoniae 6 wk. breastfeedin sensitivity.
10 Oral: Typhoid fever Nosocomial g infant; Encourage patient to
Oral: STDs caused pneumonia:400 mg IV q 8 advise a complete full course
Saunders by Neisseria hr for 10–14 days. woman to of therapy.
Nursing gonorrhea Ophthalmic infections monitor
Drug Prevention of caused by susceptible breastfed Teaching points.
Handboo anthrax following organisms not responsive infant for If an antacid is
k 2023, exposure to anthrax to other therapy: 1 or 2 loose or needed, take it at
Book 1, bacilla (prophylactic drops per eye daily or bid bloody stools least 2 hours before
Page No. use in regions or 1/2 inch ribbon of and or after dose.
236 suspected of using ointment into conjunctival candidiasis Take Proquin XR
germ warfare) sac tid on first 2 days, then (thrush, with the main meal of
Acute sinusitis apply 1/2 inch ribbon bid diaper rash) the day.
caused by H. for next 5 days. Do not touch tip of
influenzae, Acute otitis externa: 4 eye ointment or
Streptococcus drops in infected ear, tid– solution for this may
pneumoniae, or qid. contaminate the
Moraxella product.
catarrhalis Pediatric Patients Drink plenty of fluids
Lower respiratory while you are taking
tract infections: Not recommended; this drug.
Caused by E. Coli, produced lesions of joint You may experience
Klebsiella, cartilage in immature these side effects:
Enterobacter experimental animals. Nausea, vomiting,
species, P. Inhalational anthrax: 15 abdominal pain (eat
mirabilis, P. mg/kg/dose PO q 12 hr for frequent small
aeruginosa, H. 60 days or 10 mg/kg/dose meals); diarrhea or
influenzae, IV q 12 hr for 60 days; do constipation;
Haemophilia not exceed 500 mg/dose drowsiness, blurring
parainfluenza, S. PO or 400 mg/dose IV. of vision, dizziness
pneumoniae (observe caution if
Unlabeled use: Geriatric Patients or driving or using
Effective in Patients with Impaired dangerous
patients with cystic Renal Function equipment). Report
fibrosis who have For creatinine clearance of rash, visual changes,
pulmonary 30–50 mL/min, give 250– severe GI problems,
exacerbations 500 mg PO q 12 hr. For weakness, tremors.
creatinine clearance of 5–
CONTRAINDICATION 29 mL/min, give 250–500
Hypersensitivity. mg PO q 18 hr or 200–400
Not to be used mg IV q 18–24 hr. For
concurrently with patients on hemodialysis,
tizanidine. Avoid give 250–500 mg q 24 hr,
exposure to strong after dialysis.
sunlight or sun
lamps during
treatment.
DRUG
INTERACTION:
Serious and fatal
reactions have
reported in patients
receiving
concurrent
administration of
ciprofloxacin and
theophylline; if
concomitant use
cannot be avoided,
monitor serum
levels of
theophylline and
adjust dosage as
appropriate.