PHARMACEUTICAL DOSAGE FORMS AND DRUG DELIVERY SYSTEMS LABORATORY

Name: FORMENTERA, SYBYL Date: SEPTEMBER 30, 2020

ACTIVITY NO. 10
MINERAL OIL, EMULSION, USP

Objectives: At the end of the activity the student should be able to:
1. Fill in the table of formulation
2. Find emulsions at home

I. Formula 60 ml/ 1000ml = 0.06

Ingredients Amount Reduced Use

Mineral oil 500 mL 30 ml It is used for lubricating

agent

Acacia (very fine Tablet binder , emulsifier,

suspending agent , and
viscosity .

powder) 125 g 7.5 g

It is used for sweeting agent

Syrup 100 mL 6 ml

Vanillin 40 mg 2.4 mg It is used for Intoxicating

agent

Alcohol 60 mL 3.6 ml It is used for Solvent

Purified Water to make 1000 mL 60mL

Mineral oil 60 ml/ 1000ml (500ml) = 30ml Syrup 60 ml/ 1000ml (100ml) = 6ml

Acacia 60 ml/ 1000ml (125ml) = 7.5 g Vanillin 60 ml/ 1000ml (40ml) = 2.4ml

Alcohol 60 ml/ 1000ml (60ml) = 3.6ml

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II. Instructions: Fill in the table. The following are types of emulsions that you need to find in your house. If
you are not using it ask someone in your house who uses it to answer the following questions.

Type of Emulsion Lotion Cream Ointment Liniment

Name of product Myra (classic Ponds Smooth E Pau

moisturizing D’arco
vitamin lotion ) Liniment

Are you using it?

Answer each No. No. Yes No.
column with Yes or
No.

Does it have an
excellent
spreadability? Yes Yes Yes Yes
Answer each
column with Yes or
No.
Does it stay in your
skin longer? Yes Yes No. Yes
Answer each
column with Yes or
No.
Do you shake it No. No. No. No.
before you use it?
Answer each
column with Yes or
No.
Is it aesthetically No. No Yes Yes
pleasing? Answer
each column with
Yes or No.
Have you seen the Yes Yes No Yes
product being
unstable? Answer
each column with
Yes or No.

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Describe the smell Scented lotionn smells of Woody

of the product rose smell notes of unscented fregrance
ylang-ylang,
honeysuckle,
rose,
bergamot,
and white
musk
Identify the active Water, Mineral Water, Centella Naphthoq
ingredient/s in the Oil, Isopropyl Mineral Oil, Asiatica uinones.
product Palmitate, Isopropyl specificall
Petrolatum,
Palmitate, y lapachol
Glycerin, Stearic
Acid, Ceresin, Petrolatum, and beta-
Glyceryl Stearate, Glycerin, lapachone
Cetyl Alcohol, Stearic Acid,
Sorbitan Ceresin,
monopalmite, Glyceryl
Candelilla Wax, Stearate,
Triethanolamine,
Cetyl
Laureth-23,
Fragrance, Alcohol,
Carbomer, Sorbitan
Disodium Edta, Oleate,
Dmdm Candelilla
Hydantoin, Wax,
Methylparaben, Triethanola
Iodopropynyl
mine,
Butylcarbamate.
Laureth-23,
Fragrance,
Carbomer,
Disodium
Edta, Dmdm
Hydantoin,
Methylparab
en,
Iodopropyny
l
Butylcarbam
ate.
Identify one Glyceryl Glyceryl None Sorbitan
emulsifying agent Monostearate Monostearat Monoolea
in the product e te
Identify one None Carbomer Sodium None
suspending agent

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in the product

Identify one Sorbitan NoNE Polysorba None

surfactant in the MonoPalmiate te
product
Identify one Sorbitan None Polysorba None
viscosityincreasing monopalmate te
agent in the
product

Check the following that applies:

I did not use all the types of emulsions above, I asked someone.
I am using all the types of emulsions above, all answers above are based on my perspective.
I answered some of the above questions and also asked someone to fill it up.

Type of Lotion Cream Ointment Liniment

Emulsion
Rexona Deo lotion Olay Terramycin Omega
Name of
product

Are you Yes No Yes Yes

using it?
Answer
each
column
with Yes or
No.

Does it have Yes Yes Yes Yes

an excellent
spreadabilit
y? Answer
each
column
with Yes or
No.
Does it stay Yes Yes No Yes
in your skin
longer?
Answer

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each
column
with Yes or
No.
Do you No No No Yes
shake it
before you
use it?
Answer
each
column
with Yes or
No.
Is it Yes Yes Yes No
aestheticall
y pleasing?
Answer
each
column
with Yes or
No.
Have you Yes No No No
seen the
product
being
unstable?
Answer
each
column
with Yes or
No.
Describe floral. Smell like rose Unscented Minty
the smell of petals.
the product
Identify the Water, Aluminum Water/Eau, Glyce Oxytetracycline,
active Chlorohydrate, rin, Cetyl Alcohol, lidocaine, water Carboxy
ingredient/s Steareth-2, Petrolatum, ,propylene glycol, methylcel
Helianthus Annuus
in the Cyclopentasiloxan propyl gallate, lulose
(Sunflower) Seed
product Oil, Fragrance, e, Stearyl Alcohol, citric acid, Sodium,
Steareth-20, Silica Isopropyl monoethanolami D and C
Dimethyl Silylate, Palmitate, ne, α- Green
Caprylic/Capric Dimethicone, monothioglycerol number
Triglyceride, Carbomer, PEG- , sulfoxylate, 6, D and

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Disodium Edta, 100 Stearate, formaldehyde, C Yellow

Pentaerythrithyl Stearic Acid, sodium, number
Tetra-Di-T-Butyl Sodium hexahydrate, 11,
Hydroxyhydrocinna
Hydroxide, magnesium chlori Eucalyptu
mate, Hydrated
DMDM de hexahydrate s Oil,
Silica, Gelatin
Crosspolymer, Hydantoin, Light
Cellulose Gum, Iodopropynyl Mineral
Sodium Butylcarbamate, Oil,
Benzoate.Cetyl EDTA, PEG/PPG- Magnesiu
alcohol 18/18 m,
Dimethicone, Aluminu
Fragrance/Parfu m
m, Titanium Silicate,
Dioxide, Red 4 Methylpa
raben,
Oleic
Acid,
Propylpar
aben,
Purified
Water,
Sodium
Octoxyno
l-2
Ethane
Sulfonate
, Sorbitol
Solution,
Triethano
lamine,
Turpentin
e Oil.
Identify one Cetyl Alcohol Cethyl alcohol. NONE NONE
emulsifying
agent in the
product
Identify one None Cobomer Sodium Carboxy
suspending methylcel
agent in the lulose
product Sodium
Identify one None NONE Sodium Octoxyno
surfactant l-
in the

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product

Identify one None NONE None None

viscosityincr
easing
agent in the
product

Check the following that applies:

I did not use all the types of emulsions above, I asked someone.
I am using all the types of emulsions above, all answers above are based on my perspective.
I answered some of the above questions and also asked someone to fill it up.

Question:

Emulsions are naturally unstable. During the laboratory experiment, how will you produce and make sure it is a
stable emulsion? Give 5 techniques that may be useful for you in the future.

1. By using machine one example is the Rotar / Stator mixer – It can stabilized emulsion by Mixing it.
- It sucks liquids into the workhead and forces out through the holes in the stator.

2. Increasing the electrostatic repulsion (which is long range) or steric repulsion (short range).

3. To Make the emulsion stable you need to add emulsifier.

4. Another way to stabilized emulsion by used of hydrocolloids like Xanthum gum or guar gum.

5. Increase the amount of force imparted- This relates to the above point, as an increase in force during mixing
will help to reduce particle size. Increased force also, however, creates an emulsion that is much more well-
mixed. This is significant in that it enhances the product’s stability, which lengthens its shelf and overall
consumer satisfaction. Shear, cavitation, turbulence, and pressure are among some of the more common
forces used to mix an emulsion

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