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SCIENTIFIC ARTICLE

Approach to the Perpendicular Fixation of


a Scaphoid Waist Fracture—A Computer
Analyzed Cadaver Model
Shai Luria, MD,* Samih Badir, MD,* Yonatan Schwarcz, MD,* Eran Peleg, PhD,* Thanapong Waitayawinyu, MD†

Purpose In scaphoid fracture screw fixation, the screw is commonly placed along the long axis
of the bone, without consideration of the fracture plane. This position is not perpendicular to
transverse waist fractures or to the more common horizontal oblique fractures. Our aim was to
examine the feasibility and describe possible approaches to, placing a screw perpendicular
and in the center of the scaphoid waist fracture.
Methods Computed tomography of 12 cadaver wrists was performed in 3 positions to examine
possible approaches in flexion, neutral, and extension of the wrist. The scans were evaluated
using a 3-dimensional model that simulated horizontal oblique (60 ) and transverse (90 )
fractures. We examined all possible approaches for screw positioning and their deviation from
the axis perpendicular to the fracture and in the center of its plane.
Results The preferred approaches for a perpendicular screw in a horizontal oblique fracture
were found to be proximal-dorsal in flexion or transtrapezial in the extended or neutral po-
sitions (through the volar-radial trapezium). In transverse fractures, the possible approaches
were proximal-dorsal or transtrapezial in the flexed or neutral positions and distal in the
extended position (volar to volar-radial trapezium). In these approaches, the screw could be
placed perpendicularly (deviating by < 10 ) and in the center of the fracture in all specimens.
Conclusions According to this model, it appears feasible to place a perpendicular screw in the
center of a horizontal oblique waist fracture using a proximal-dorsal approach in flexion or a
transtrapezial approach in neutral or extension positions of the wrist. Palpable landmarks may
be used as additional guides to direct these approaches according to the clinical setting.
Clinical relevance Perpendicular screw fixation of horizontal oblique or transverse scaphoid
waist fractures is a possible option, if chosen for its biomechanical advantages. (J Hand Surg
Am. 2019;-(-):1.e1-e10. Copyright Ó 2019 by the American Society for Surgery of the
Hand. All rights reserved.)
Key words Horizontal oblique fracture, perpendicular screw fixation, scaphoid fracture,
transtrapezial approach, waist fracture.

From the *Department of Orthopedic Surgery, Hadassah-Hebrew University Medical Center, Corresponding author: Shai Luria, MD, Department of Orthopedic Surgery, Hadassah-
Jerusalem, Israel; and the †Department of Orthopedic Surgery, Thammasat University, Hebrew University Medical Center, Kiryat Hadassah, POB 12000, Jerusalem 91120, Israel;
Pathumthani, Thailand. e-mail: shail@hadassah.org.il.
Received for publication August 5, 2018; accepted in revised form July 23, 2019. 0363-5023/19/---0001$36.00/0
https://doi.org/10.1016/j.jhsa.2019.07.009
No benefits in any form have been received or will be received related directly or indirectly
to the subject of this article.

Ó 2019 ASSH r Published by Elsevier, Inc. All rights reserved. r 1.e1


1.e2 PERPENDICULAR FIXATION OF SCAPHOID FRACTURE

S
CAPHOID FRACTURES ARE COMMONLY treated by different wrist positions. Our hypothesis was that a
surgical fixation.1 Placement of a single cannu- perpendicular screw could be placed in the center of
lated screw in the center of the proximal frag- the fracture plane, either from a proximal approach
ment was recommended by Adams et al,2 and later with the wrist flexed or from a distal approach in a
found to be superior to eccentric positioning of the neutral position.
screw in a clinical study of fracture nonunions,3 as
well as in a cadaver model of a transverse waist frac-
METHODS
ture.4 This approach that disregards the fracture and
directs fixation along the scaphoid long axis has A sample of convenience of 6 pairs of upper limbs of
become common practice,5 although its biomechan- embalmed cadavers cut through the midshaft of the
ical superiority has been questioned.6,7 The long- humerus with all soft tissue preserved were assessed
axis screw was found to be at an angle to transverse clinically and radiographically to rule out previous
fractures and, to a greater extent, to the majority of trauma or surgery as well as anatomical abnormal-
fractures which are horizontal oblique.8,9 Kupperman ities. The Herbert classification10 was used to simu-
et al9 demonstrated that part of the forces of a long- late the most common fractures, specifically,
axis screw will, in fact, be perpendicular to the frac- horizontal oblique and transverse waist fractures (B1
ture. The authors examined the longest screw, within and B2, respectively). These 2 configurations were
a defined safe zone, from a classic approach. The au- chosen based on the typical waist fracture, which is
thors suggest that the surgeon may take the fracture horizontal oblique,8 or a transverse fracture.18,19
plane into account by “altering the screw starting According to the aims of the study, we did not take
point and trajectory” gaining more screw force into account the degree of displacement or commi-
perpendicular to the fracture.9 nution of the fracture but rather its morphology in its
In basic biomechanical terms, placing a screw reduced form.
perpendicular and in the center of any fracture plane A CT scan of each wrist was carried out in 3 po-
has an advantage. A finite element examination sitions to examine the approaches in positions
demonstrated this advantage in unstable Herbert B mimicking those possible in practice: maximum
type scaphoid fractures,10 comparing a screw flexion, neutral position (without radial or ulnar de-
perpendicular to the fracture over a long-axis screw.6 viation), and maximum extension. The scans were
Another 3-dimensional simulation of actual fracture performed with the wrist held in the extremes of these
computed tomography (CT) scans demonstrated the positions. The neutral scan was made by laying the
superior compression forces created by the perpen- cadaver arm straight on the scan table. The slice
dicular screw.7 In these studies, the perpendicular spacing was set at 1 mm with a pixel size of 0.195 
screw would be in the center of the fracture, not in an 0.195 mm2. Each wrist CT (3 positions for each
eccentric position.4 An additional advantage to a wrist) was examined using commercially available 3-
perpendicular screw was demonstrated in another dimensional analysis software (Amira Dev 5.33;
finite element study, indicating that a perpendicular Mercury Computer Systems, Chelmsford, MA) with
screw in the horizontal oblique fracture took up a the following steps (Fig. 1):
smaller area of the fracture surface needed for 1. Segmentation of the scaphoid geometry was per-
apposition and healing in comparison with a long- formed with an automated tool followed by minor
axis screw.11 Several clinical studies have described manual adjustments for each axial CT image,
aiming the fixation with a screw perpendicular to the resulting in a scaphoid surface mesh.8 Scaphoid
scaphoid fracture as a standard approach.12,13 longitudinal axis computation was performed us-
Dorsal proximal and volar distal approaches are ing a principal component analysis algorithm.8
the most typical in both open and percutaneous Volar-dorsal and radial-ulnar directions were
techniques used today.14e16 As suggested, to place a based on the distal radius joint surface as defined
screw perpendicular to a horizontal oblique or by 4 anatomical markers placed on the joint edges
transverse fracture, these standard approaches may on the 3-dimensional model—the posterior and
require alteration.9,17 The aim of our study was to anterior edges of the ridge between the scaphoid
examine altering the approaches in order to be able to and the lunate facets, the middle of the ulnar
place a perpendicular screw in the center of the notch, and the farthest edge of the styloid process.
fracture. This screw may not be as long as suggested 2. Creation of virtual Herbert type B1 and B2 frac-
by Kupperman et al,9 but would not be eccentric. We tures. The B1 (horizontal oblique) fracture was set
chose a cadaver model that allowed us to examine at 60 to the longitudinal axis and inclined in the

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dorsal direction (distal volar, proximal dorsal)


based on data of the most common fracture
inclination.8 The B2 (transverse) fracture was set
at exactly 90 to the scaphoid longitudinal axis.
Both fractures crossed the longitudinal axis at its
center. A line was marked perpendicular (90 ) and
in the computed middle of the fracture plane,
representing the screw in the optimal central and
perpendicular position.
3. The possible approaches for screw placement to
achieve this optimal position were examined,
including measurement of the possible deviations
from the axis trajectory (with a free range for
screw placement options). The screw width was
set to 3.6 mm, comparable with a Mini-Acutrak2
screw (Acumed, Hillsboro, OR). We took into
account the largest diameter, not the change in
screw diameter. For each specimen in each wrist
position, the possible approaches considered the
adjacent bones, including and excluding penetra-
tion into these bones, in an attempt to get as close
as possible to the optimal position. Deviation of
the best possible screw axis from the optimal
position was measured for all approaches and
wrist positions. The approaches achieving the best
position were defined as those that deviated less
than 10 from the optimal position (angle of de-
viation) with as little offset as possible from the
center of the fracture plane.
The reliability of the measures were examined by
repeating all stages of the computation by the same
research assistant on 4 random unmarked specimens,
with 1 week between each measurement session. The
intraobserver error found an insignificant difference
between the pairs of measurements (Wilcoxon
nonparametric paired test) and a high correlation
between these pairs (between 0.8 and 1.0; Spear-
man’s nonparametric correlation coefficient).
For each of these approaches, additional measures
were collected:
1. The length of a virtual screw through the scaphoid
between the scaphoid cortices. In the approaches
achieving a central perpendicular axis, we exam-
ined the proportion of screw length proximal and
distal to the fracture plane. FIGURE 1: A flowchart of the steps carried out for each sample.
2. The distance of each virtual screw entry point
from palpable or recognizable anatomical land- tubercle, a longitudinal axis was drawn along the
marks: (1) for the distal approach: the volar-radial radius, through the tubercle, to the radiocarpal joint
edge of the trapezium (over the scaphoid tuber- and the distance to the entry point was measured
osity) (Fig. 2); (2) for the proximal approach: radial or ulnar to this axis along the joint line
Lister tuberosity of the radius and apex of the (Fig. 3). The apex of the dorsal scaphoid ridge may
dorsal scaphoid ridge (Fig. 3). For Lister’s be appreciated through an open dorsal approach.

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1.e4 PERPENDICULAR FIXATION OF SCAPHOID FRACTURE

FIGURE 2: Three-dimensional view of the volar wrist in neutral position and a transtrapezial approach for placing a perpendicular screw
through the center of a horizontal oblique fracture (white surface within the waist of purple-colored scaphoid). The distance between the
entry point through the volar-radial trapezium and the edge of volar-radial corner of the trapezium, over the scaphoid tuberosity (black
line on trapezium measuring 6.3 mm) is shown. In the scaphoid itself, the blue line is the longitudinal axis of the bone and the red line
depicts the perpendicular screw. Inset: Dorsal view of the same wrist. The screw trajectory (red line) exits through the dorsal-radial
aspect of the distal radioulnar joint.

3. The exit direction was recorded for each approach, overall success of achieving an optimal location of
in relation to similar anatomical markers (Figs. 2, the fixation axis (with no offset and < 10 angle
3 insets). deviation). Using a sample of convenience and given
4. The wrist angle was measured for each position in 72 simulations, while defining a minimal success rate
a coronal view of the 3-dimensional model, be- of 90%, a 95% CI level was found to be between 81%
tween the radius long axis and the dorsal aspect of and 96%. We regard the lower limit of the 95% CI as
the middle finger metacarpal. sufficient for the purpose of this study, considering
the strict criteria of optimal location, high level of
Outcome measures accuracy of the computer model, and as based on a
The outcome measures were the angle and the rela- previous publication that demonstrated lower success
tive distance on the fracture plane between the best rates and differences in these rates using different
axis achieved and the exact central perpendicular approaches.17
location (Fig. 4). As described previously, we named Data analysis: Repeated measures analysis of variance
these variables the angle of deviation (from the was used in order to examine the effect of wrist po-
optimal perpendicular screw axis position)17 and the sition and approach as well as these factors and screw
offset (distance from the center of the fracture plane). length, for each type of fracture.
In the approaches that were found to achieve a central
perpendicular axis, the virtual screw length as well as
the distance of the entry point to specific anatomical
markers were measured. RESULTS
The position of the best possible screw axes for all
Statistical methods specimens is summarized in Table 1. Of the 12
Sample size: The sample size was calculated for a 95% specimens examined, 1 was omitted owing to defor-
confidence interval (95% CI) for the percentage of mity of its distal radius as seen on the CT scan.

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FIGURE 3: Three-dimensional dorsal view of a flexed wrist and a proximal approach for placing a perpendicular screw through the
center of a horizontal oblique fracture (white surface within the waist of a purple-colored scaphoid). The distance between the entry
point into the scaphoid radial base can be measured A from the apex of the dorsal scaphoid ridge (white line on scaphoid, measuring
13.2 mm) or B from Lister tubercles long axis (black line) along the radiocarpal joint line (white line; measuring 2 mm). The yellow
sphere on the radial joint surface marks the dorsal radial joint surface. In the scaphoid itself, the blue line is the longitudinal axis of the
bone and the red line depicts the perpendicular screw. Inset: Volar view of the same wrist. The screw trajectory (red line) exits through
the volar-radial trapezium.

In horizontal oblique and transverse fractures, the deviation and no offset); (2) transtrapezial approach
mean angle of deviation from the optimal screw po- through the volar-radial angle of the trapezium,
sition was affected by the position of the wrist with the wrist flexed (2.7 deviation and no offset)
(extension, flexion, or neutral) (P < .05) and the or neutral (3.2 deviation and no offset); or (3)
approach for screw placement (proximal, distal, or distal approach, volar and radial to the trapezium in
transtrapezial) (P < .05 and P ¼ .05, respectively). an extended wrist (5.9 deviation and no offset).
The combined effect was significant as well (P ¼ .05 We did not measure the entry points to the trans-
and P < .05, respectively). trapezial approach in extension, although it was
In horizontal oblique fractures, the smallest mean found to be adequate (7.3 deviation with no
angle of deviation was achieved by placing the virtual offset), given the results with smaller angles ach-
screw in 2 directions: (1) Through a proximal ieved with the transtrapezial approach in a neutral
approach with the wrist flexed (0 deviation and no or flexed wrist.
offset from the perpendicular axis) or (2) A distal Virtual screw lengths (Table 2) were measured for
transtrapezial approach, through the volar-radial the approaches achieving central perpendicular axes.
corner of the trapezium, with the wrist extended (0 We found that the screws would be shorter for hori-
deviation and no offset) or neutral (7.3 deviation and zontal oblique fractures than transverse fractures,
no offset). An adequate central axis (< 10 deviation) with each of the attempted approaches (P < .05). The
could be achieved with a proximal approach with the approach or position of the wrist did not affect screw
wrist extended, although this required an approach length. The distance between the axis entry points
volar to the radius. We consider this less appropriate, and the anatomical landmarks for the approaches are
especially for a percutaneous technique. presented in Table 2. In the examined cases achieving
In transverse fractures, the smallest mean angles a central perpendicular axis, a mean of 48% of the
were achieved placing the virtual screw through screw (SD, 0.02%) was in the proximal fragment.
different approaches: (1) Proximal approach, with The mean wrist angle measured radiographically in
the wrist in flexion (0 deviation and no offset from the neutral position was 10 (SD, 4 ), in flexion, 106
perpendicular axis), or in a neutral position (6.4 (SD, 9 ), and in extension, 103 (SD, 9).

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FIGURE 4: AeC Schematic representation of a lateral view of the scaphoid and the study outcome measures. The fracture is
demonstrated in green and the long axis of the scaphoid in brown. The dashed black line represents the optimal axis, perpendicular and
in the center of the fracture plane. The red line represents the best position achieved from a proximal approach A, C or distal approach B.
The distance between the red line and the dashed black line on the fracture plane is the offset and the angle between these lines, the
deviation angle. A The position is clearly inadequate, yet this is the best position possible when attempting to place a perpendicular
screw from a proximal approach with the wrist in neutral.

DISCUSSION The proximal approach should be performed with


In this computer-analyzed cadaver study, we the wrist fully flexed. In a percutaneous approach
demonstrated the possible positioning options of a under the specific conditions described here, the entry
screw perpendicular and in the center of a waist point should be slightly (2 mm) radial to the long axis
fracture. According to this model, in the common of Lister tubercle of the radius. In an open approach
horizontal oblique fractures, this can be (or percutaneously with the aid of fluoroscopy), it
achieved through a standard proximal approach or should be 12 mm proximal to the apex of the
the less commonly used distal transtrapezial scaphoid dorsal ridge. Under these conditions, the
approach. aim of the drilled Kirschner wire should be toward

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the ulnar-volar aspect of the trapezium, palpating the

Offset
volar aspect of the thumb carpometacarpal joint or

0
0
0
scaphoid tuberosity (Fig. 3 inset). A transtrapezial

Transtrapezial
approach with the wrist in a neutral position can
achieve the same trajectory through the volar-radial

Deviation

3 ( 6)‡
7 ( 7)
3 ( 5)
angle
corner of the trapezium (8 mm from its volar edge
Deviation and Offset of Best Axis for Each Wrist Position From the Exact Central Perpendicular Approach for Screw Placement

in this model) and aimed toward the dorsal-radial


aspect of the distal radioulnar joint (Fig. 2 inset).
The transtrapezial approach in full extension may be
Transverse (90 ) Fracture

Offset
performed through the volar-radial corner of the tra-
0
0
0
pezium (7 mm from its edge in this model) aiming
Distal

toward the volar aspect of the scaphoid fossa. In cases


10 ( 10)† in which preliminary fixation of a displaced fracture
Deviation


6 ( 7)
16 ( 9)
angle

limits the positioning of the wrist, the approach for


final screw placement can be chosen according to
wrist position.
Entry point *volar to radius, †volar and radial to trapezium, ‡through volar radial trapezium, §radial and dorsal to trapezium, or kdorsal to radius.

It should be noted that the use of Lister tubercle or


Offset

the dorsal aspect of the distal radioulnar joint is


1 ( 1)
0
0

highly dependent on the position of the wrist. All of


Proximal

the landmarks presented were measured in order to


examine their use as possible additional tools when
Deviation

30 ( 8)*

aiming the fixation wire. Considering the consistency


angle

6 ( 7)
0

in their position in this model, it is possible that they


be used as additional guides for an approach, under
the conditions described here, in neutral position or
Offset

full flexion or extension of the wrist with no devia-


0
0
0
Transtrapezial

tion. These guides cannot replace the use of fluo-


roscopy or direct visualization for wire positioning.
Deviation

Owing to the variability of wrist position, variability



angle

14 ( 9)
7 ( 8)‡

in the ease of palpation of these landmarks, and other


clinical considerations, these measures may not be

0

relevant in many clinical cases.


Horizontal Oblique (60 ) Fracture

A similar attempt at examining the feasibility of a


0 ( 1)
e1 ( 1)
0 ( 0)
Offset

perpendicular screw has recently been published.17


The authors examined CT scans of actual patients
Distal

simulating fractures and different positions of the


wrist using the computer model. The authors found

26 ( 5)†
Deviation

22 ( 9)
30 ( 2)

the best possible nonobstructed screw placement in


angle

horizontal oblique fractures to be 40 in the standard


volar approach and 14 in the dorsal approach.17 In
contrast, in the current report, we have demonstrated
approaches enabling placement of perpendicular and
Offset

0 ( 1)

0 ( 0)
0

central screws. There are several differences between


Proximal

the 2 studies. In the current study, we examined


actual positions of cadaver wrists for the creation of
Deviation

the computer model and not computer simulations of


9 ( 14)*

24 ( 8)k
angle

wrist position. We chose to position the screw in the


center of the fracture and not the waist area, as in the
previous report.17 We examined the transtrapezial
Approach

approach and not only the standard volar approach


TABLE 1.

position
Wrist

Extended

and attempted to describe and quantify the entry point


Neutral
Flexed

and exit direction of the optimal approaches. Finally,


there may be a difference in the anatomical features

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TABLE 2. Screw Length and Entry and Exit Points of Preferable Approaches to Place a Central Perpendicular
Fixation Screw
Horizontal Oblique
(60 ) Fracture Transverse (90 ) Fracture

Extended Approach Transtrapezial Distal


Screw length, mm 23 ( 2) 25 ( 2)
Entry point distance to volar-radial 7 ( 2) 6 ( 1)
edge of trapezium, mm
Exit landmark Volar/distal to Ulnar side of radial
scaphoid fossa shaft, proximal to
distal radioulnar
joint
Flexed Approach Proximal Proximal Transtrapezial
Screw length, mm 23 ( 3) 26 ( 2) 25 ( 3)
Entry point distance to
Volar-radial edge of the trapezium 8 ( 3)
Longitudinal axis of Lister tuberosity of 2 ( 2) 3 ( 2)
the radius along radiocarpal joint line,
mm
apex of dorsal scaphoid ridge, mm 12 ( 2) 9 ( 2)
Exit landmark Volar/ulnar trapezium Volar/radial Ulnar/distal to Lister
trapezium tubercle
Neutral Approach Transtrapezial Proximal Transtrapezial
Screw length, mm 24 ( 3) 26 ( 2) 26 ( 2)
Entry point distance to
Volar-radial edge of the trapezium, mm 8 ( 2) 5 ( 1)
Longitudinal axis of Lister tuberosity of 4 ( 2)
the radius along radiocarpal joint line,
mm
Apex of dorsal scaphoid ridge, mm 9 ( 1)
Exit landmark Dorsal/radial aspect of Volar/radial Ulnar/distal to Lister
distal radioulnar edge of the tubercle
joint trapezium

and joint range of motion of live European patients17 oblique fractures in comparison with transverse
and cadavers of Thai origin, which were used in our fractures. We believe this to be of limited significance
study. when comparing different screw trajectories. In gen-
The use of a transtrapezial approach may not be a eral, a longer screw for the fixation of the scaphoid
standard approach in most clinical practices, yet this fracture has been considered superior biomechani-
is not novel.20,21 The transtrapezial approach may cally. Yet the evidence to support this is a cadaver
enable superior screw positioning in comparison with study24 that tested 2 screw lengths along the same
a standard volar approach that necessitates excision trajectory in the same specimens and screw holes,
of part of the trapezium or manipulation of the joint examining long-axis screw fixation of transverse
and has been reported to have a higher risk of injuring fractures. In contrast, a different cadaver study
the scaphotrapezial ligament.22 It has been demon- examining perpendicular versus long-axis screw fix-
strated that the transtrapezial approach does not result ation of horizontal oblique fractures found the
in significant arthritic changes to the scaphotrapezial perpendicular position to be as strong, although
joint.23 In order to achieve superior screw posi- significantly shorter than the long-axis screw.18 It is
tioning, this approach may find new popularity. reasonable to consider the position of the screw in
We found virtual screw lengths were significantly relation to the fracture plane and not only its length as
shorter for perpendicular fixation of horizontal factors affecting fixation stability.18 This has recently

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been termed effective compression length, a combi- must be examined specifically when choosing the
nation of screw length and angle to fracture plane, in approach. Finally, we did not evaluate wrist devia-
a long-axis screw.9 In this study, we did not examine tion, which is more difficult to simulate consistently.
the implications of placing a long-axis screw. We We chose to examine reproducible positions, which
attempted to examine the option of perpendicular and are commonly used and are easy to replicate.
central fixation, even if this meant we needed to There are several advantages to a central perpen-
approach these fractures differently and that the screw dicular screw, and in some locations, it is in clinical
may be shorter. use. This computer-analyzed cadaver study clearly
The position of the perpendicular screw may have showed that a central perpendicular screw is a
an additional biomechanical advantage. According to promising alternative in horizontal oblique as well as
a finite element analysis of cadaver bone density and transverse fractures by implementing slight variations
cortical thickness, more rigid fixation can be achieved to standard approaches. Application of these specific
between the midcarpal side of the tuberosity and the approaches in clinical practice may not be simple at
radial side of the proximal pole25 (Fig. 3). Although a times, yet the additional tools described may direct
similar direction has been demonstrated in the current the surgeon when attempting to place a central
study, we did not examine bone density and cortical perpendicular screw in the scaphoid waist fracture.
thickness along the screw axis to demonstrate this.
The limitations of this study relate mainly to the
model. Soft tissue constraints might result in more ACKNOWLEDGMENTS
difficult positioning of an implant than in the com- We recieved a grant from the Thammasat University
puter model, although this was taken into account to Research Fund. We would also like to acknowledge
some extent with respect to the screw width. This Dr. Tali Bdolah-Abram of the Hadassah-Hebrew
computer model cannot take into account other con- University Medical School for her help with the
straints dealt with in clinical practice, such as limited statistical analysis.
range of wrist motion, significant swelling, or bony
deformity. Wrist position examined in this study on REFERENCES
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1.e10 PERPENDICULAR FIXATION OF SCAPHOID FRACTURE

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J Hand Surg Am. r Vol. -, - 2019

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