CLEFT LIP AND CLEFT PALATE

Transmission of multiple genes aided by Polygenic in heritance or

teratogenic factors environmental influences

Cleft lip Cleft palate

Fusion fails to occur in varying

degrees Palatal process does not
close as usual at
approximately weeks 9 to
12 intrauterine life.

Small notch in the upper lip

to total separation of the lip

Incomplete closure
in the midline and
Facial structures up in the may in hard palate
floor of the nose involve in hard
palate

The upper teeth and gingiva

absent
Separate
anomaly or in
conjunction
with a cleft lip
Split in the lip and Difficulty Nasal
Chronic ear
roof of the mouth swallowing speaking
infection
(palate) voice

Difficulty with
feedings