DRUG CLASSIFICATION/INDICATI MECHANIS CONTRAINDICATION ADVERSE DOSE, NURSING

ON M OF REACTION ROUTE, RESPONSIBILITI

ACTION FREQUENC ES
Y
Generic  Acute bacterial worsening Binds to the  Contraindicated in CNS: fatigue, -500 mg P.O. -Monitor patient
name: of COPD caused by 50S subunit patients headache, for superinfection.
AZITROMYCI Haemophilis influenza, bacteria hypersensitive to somnolence, Drug may cause
N Moraxella catarrhalis, or ribosomes, azithromycin, dizziness. overgrowth of non-
Streptocccus pnemoniae; blocking erythromycin, or CV: chest pain susceptible bacteria
Brand name: uncomplicated skin and protein other macrolide or palpitations or fungi.
AzaSite, skin-structure infections synthesis; ketolide antibiotics EENT: eye irritation -Monitor patient
Zithromax, caused by Staphylococcus bacteriostatic and in those with (ophthalmic) for CDAD, which
Zmax aureus, Sterptococcus or history of GI: abdominal pain, may range in
pyogens second-lined bactericidal, cholestatic jaundice anorexia, diarrhea, severity from mild
therapy for phyryngitis or depending on or hepatic nausea, vomiting, diarrhea to fatal
tonsillitis caused by concentration dysfunction from pseudomembranous colitis
S.pyogens prior use of colitis, dyspepsia, -Consider full risk
 Community-acquired azithromycin flatulence, melena profile when
pneumonia caused by C.  Don’t use oral drug Hepatic: cholestatic choosing
pneumoniae, H influenza, in patients with jaundice appropriate
M. pneumoniae, or S. pneumonia or in Skin: antibiotic therapy.
pneumoniae those with photosensitivity Alternative
 Acute bacterial sinusitis moderate to severe reactions, rash pain macrolide or
caused by H. infdluenzae, illness or risk at injection site fluoroquinolone
M catarrhalis or S. factors (such as pruritus. class drugs also
pneumoniae cystic fibrosis, Other: angioedema have potential to
 To prevent disseminated nosocomially cause QT-interval
Mycobacterium avium acquired infections, prolongation and
complex in patients with known or other significant
advanced HIV infection suspected adverse effects.
 Bacterial conjunctivitis bacteremia; -Warn patient to
caused by coryneform hospitalized, seek immediate
group G, H. influenza elderly, or medical care for
Staphylococcus aureus, debilitated irregular heartbeat,
 Streptococcus mitis group. patients; or shortness of
patients with breath, dizziness or
immunodeficiency fainting.
or functional
asplenia.
 Elderly patients
may be at
increased risk for
drug associated QT-
interval effects.

DRUG CLASSIFIACATION/INDICATI MECHANISM CONTRAINDICATION ADVERSE REACTION DOSE, NURSING

ON OF ACTION ROUTE, RESPONSIBILI
FREQUENC TIES
Y
Bespri Initial treatment of CV disorders eg, Thought to -Avoid use in patients with -GI disturbances eg, 75-100 mg Give the
n angina pectoris & MI. Prevention of produce severe hepatic impairment nausea, dyspepsia & medication on a
cerebrovascular disorders eg, analgesia and or history of active peptic vomiting. Urticaria & schedule rather
stroke.  exert its anti- ulcer disease. other skin eruptions, than as needed.
inflammatory -use cautiously in patients angioedema, rhinitis &
effected by with GI lesions impaired severe/fatal paroxysmal -Monitor elderly
inhibiting renal function, bronchospasm & dyspnea. patients closely
prostaglandin hypoprothrombinemia, Increased bleeding time, because they may
and other vitamin K deficiency, decreased platelet be more
substances that thrombotic adhesiveness & susceptible to
sensitize pain thrombocytopenic purpura. hypoprothrombinemia aspirins toxic
receptors. Drug (large dose). May exhibit effects.
may relieve cross-sensitivity to other
fever through NSAIDs. Symptoms of -Monitor patient
central action in salicylism eg, dizziness, for
the tinnitus, deafness, hypersensitivity
hypothalamic sweating, nausea & reactions such as
heat-regulating vomiting, headache & anaphylaxis and
center. In low mental confusion; trauma.
doses, drug also
appears to
interfere with
clothing by
keeping a
platelet-
aggregating
substance from
forming.
 DRUG CLASSIFIACATION/INDICATI MECHANISM CONTRAINDICATIO ADVERSE DOSE, NURSING
ON OF ACTION N REACTION ROUTE, RESPONSIBILITIES
FREQUENC
Y
Provasc - Chronic stable angina, Inhibits calcium -contraindicated in CNS: Oral ; Monitor patient carefully.
vasospatic angina; to reduce ion influx patients hypersensitive headache, 500mg /tab Some patients, especially
Generic risk of hospitalization across cardiac to drug. fatigue, those with severe
name – because of angina; to reduce and smooth- -use cautiously in dizziness obstructive CAD, have
amlodipine risk of coronary muscle cells, patients receiving other CV: edema, developed increased
revascularization procedure dilates coronary peripheral vasodilators, flushing, frequency, duration or
in patients with recently arteries and especially those with palpitations severity of angina or acute
documented CAD by arterioles and GI: nausea, MI after inhibition of
severe aortic stenosis or
angiography and without HF decrease BP abdominal calcium channel blocker
hypertrophic
or with LVEF less than 40% and myocardial pain therapy or at time of
- Hypertension oxygen cardiomyopathy with Respiratory: dosage increase.
demand. outflow tract pulmonary
obstruction, and in edema,
patients with HF with dyspnea
reduced LVEF. Because Skin: prutish,
drug is metabolized by rash.
the liver, use cautiously
and reduce dosage in
patients with severe
hepatic diseases.