Newborn babies, especially premature infants, are more susceptible to bloodstream infection.

Babies in our neonatal intensive care unit (NICU) often have immature immune systems. They are
exposed to many different caregivers and may have multiple blood tests, IV lines, and other
invasive procedures. This care is needed for babies to grow and thrive, but it also places them at
risk for infection.

Bloodstream infection is one of the most serious complications in the NICU. Babies can become
very ill and may have to stay longer in the hospital.

Our NICU team is committed to doing everything possible to prevent bloodstream infection. Many
bloodstream infections happen when babies have a special tube called a “central line.” A central
line is a thin tube put in a baby’s vein, usually in the neck, chest, arm, or leg. The line is often used
to draw blood, give the baby fluids, give medicine, and give food so the baby gains weight and
grows.

Central lines can be life-saving, but also come with risks, including infection. Our NICU team has
put measures in place to prevent such infections. These include:

 Inserting central lines only when they are clearly needed.

 Training staff who insert central lines to use careful sterile techniques.

 Following a checklist to be sure all infection prevention steps are taken.

 Wearing a cap, mask, sterile gown and gloves to keep the area clean.
 Carefully cleaning the skin where the line will be inserted.
 Having all staff clean their hands before handling the line.
 Disinfecting the line before injecting medications.
 Using a closed medication system to protect the inside of the line.
 Removing lines as soon as they are no longer needed.

With these steps in place, the team has been able to decrease the number of NICU central line
infections to zero for a very long time. In fact, we have experienced no central line infections in our
NICU in more than a year. Not all infections can be prevented, but our NICU team continuously
looks for new and better ways to prevent infection.

Hospitals across the country use the Standardized Infection Ratio (SIR) to compare central line
infection rates with other hospitals. The SIR is a ratio comparing the actual number of infections at
Women & Infants Hospital to the number of predicted infections based on the national benchmark,
adjusting for risk factors like birthweight. Therefore:

 A SIR of 1 indicates the number of infections is as expected.

 SIR of less than 1 is better than expected.
 A SIR of greater than 1 is worse than expected.

Women & Infants’ SIR is 0.22, which means the infection rate here is better than expected when
compared to other hospitals.