HAAD Exam 06/08/2020

Dr. Omar Ahmed

‫الحمدهلل كان االمتحان سهل و متكرر كله بس محتاج تركيز في االسئلة‬

‫من ناحية اذا في إكسبت ( ما عدا ) وال ال و المسائل كان اغلبها متكرر و‬
‫تعويض مباشر بس بتركيز في موضوع الوحدات‬.

‫ و النجاح للجميع‬-‫ال تنسوني من دعائكم و بالتوفيق‬.

1. All of the following are non-competitive acetyl cholinesterase inhibitors,

except:
1- Donepezil
2- Rivastigmine
3- Galantamine (reversible and competitive ache inhibitor)
4- Tacrine

2.Mepredine not suitable for long time because???

1-cardiotoxicity
2-neurotoxicity (elderly)
3-nephrotoxicity

3.-case about patient recently widowed, is suffering from severe depression,

is taking imipramine(TCA) block the reuptake of :
1- serotonin
2- norepinephrine
3- serotonin and norepinephrine
4- dopamine

4.same case about the widow

TCA metabolized by:
a-CYP 450
b-amine hydroxlase
c-alcohol dehydrogenase

5.Same case about the widow

TCA block all of the following receptors except:
1- Histaminic receptors
2- Alpha adrenergic receptors
3- Beta adrenergic receptors
4- Muscarinic receptors (cholinergic)
6.Same case about the widow:
TCA used in all of the following except:
1- Panic disorders
2- Schizophrenia
3- Migraine
4- Neuropathic pain

7.Metabolic effects of BB include all of the following except:

1- Decreased glucagon release
2- Decreased glycogenolysis
3- Hypertriglyceridemia
4- Hyperglycemia

8.Least effect for BB in :

1- Benign prostatic hyperplasia
2- Myocardial infarction
3- Arrhythmia
4- Angina pectoris

9.All of the following decrease the effects of BB By interfering with it

except:
1- Phenytoin
2- Phenobarbital
3- rifampin
4- Fluoxetine (increase effect of BB)

10. Female patients suffering from absence seizures, which of the

following is not indicated:
1- Ethosuximide
2- Lamotrigine
3- Diazepam
4- Carbamazepine

11. we are using all to treat absence seizure except: 

a- phenytoin
b- valproic acid
c- ethosuximide
d- lamotrigine

12. What is the drug of choice for status epilepticus :

1- Phenytoin
2- Carbamazepine
3- Lamotrigine
4- Valproate

13. All of the following anti-epileptic drugs are avoided in pregnancy

except:
1- Phenytoin
2- Valproate
3- Diazepam
4- clonazepam

14. Doctor wants to discontinue anti-epileptic drug for female patient,

which of the following guarantees low recurrence:
1- EEG
2- History of frequent seizures
3- Onset in childhood
4- MRI

15. Anti cholinergic used for motion sickness :

-scopalamine

16. Patients develop tolerance against all of the following effects of

morphine except:
1- Respiratory depression
2- Euphoria
3- Analgesia
4- Pinpoint pupil ( tonic pupil )

17. All used for Morphine dependence except : 

a. Methadone 
b. Codeine 
c. Clonidine 
d. Buprenorphine

18. Case about patient suffering from severe skeletal muscle rigidity and
is diagnosed with myasthenia gravis, which of the following is NOT true:
1- Diagnosed by edrophonium
2- Glucocorticoids are not useful in this condition
3- Autoimmune disease caused by antibodies against ACH receptors at motor
endplate

19. All of the following are used for treatment of acute mania except:
1- Lorazepam
2- Chlorpromazine
3- Lithium
4- Valproate

20. Coma and respiratory depression caused by morphine overdose can be

reversed by:
1- Naltraxone ( check please )
2- methadone
3- codeine

21. Which drug is not used in parkinson’s disease:

1- Chlorthalidone,
2- Bromocriptine
3- Amantadine
4- Rasagiline

22. Which of the following is CI in Parkinson:

1- Haloperidol
2- levodopa

23. Long case about Parkinson patient:

What is the effect of carbidopa on levodopa:
1- Decrease its metabolism in the CNS
2- Decrease its peripheral decarboxylation to dopamine

24. What are the symptoms of parkinson:

1- Tremors and agitation
2- Inability to initiate voluntary movements
3- Abnormal posture and gait
4- all

25. Which of the following vitamins decreases the effects of levodopa

when taken concomitantly :
1- Vit B6 pyridoxine
2- Vit B12
3- Vit B1
4- Vit B5

26. The decrease in the effect of levodopa occurs within:

11- After 5 years
2- After 3 years
3- After 2 years
4- From the 3rd to the 5th year

27. Pilocarpine is used in all of the following except:

1- In narrow angle glaucoma
2- Alternatively with mydriatics to separate the iris
3- In closed angle glaucoma
4- Standard one for open glaucoma

28. phenytoin side effect ,all except

a) gingival hyperplasia
b) nystagmus
c) nephrotoxicity
29. Which of the following is ultra-short barbiturates:
Penobarbital (long action)
1- Thiopental
2- buprenorphine

30. Regarding Fluxetine : ( came as a table and you choose )

a. half life is 50 hrs
b. have a metabolite as active as the parentdrug
c. used in bulimia nervosa
d.undergo first pass effect
e. ALL

31. Which of the following used to make mydriasis in

checking refractive errors?
Atropine
Tropicamide

32. case scenario about female patient have GOUT was weak & dizzy &
fatigue and another problems like she can’t raise her hand and having some
blood disorders like agrnaulocytosis and leucopenia and type of anemia which
anti gout are probably to cause this Side effects :
a- allopurinol
b- colchicine

33. the qs about pharyngitis, the patient was penicillin allergic but the
organism is penicillin sensitive
A. Penicillin
B. Cephalosporin
C. Azithromycin
D. Tetracycline

34. Which one of tetracyclines is suitable for renal failure pt ( it was in a

case ) :
a. Doxycycline
b. Minocycline
c. Tetracycline
35. which of the following is not fungus:-
a-mushroom
b-E.coli

36. Bacteria move by :-flagella

37. mitochondrial toxicity,, ANTIVIRAL used:

a-lamivudine

b-amatidine

c-zidovudine

38. antiviral used in Parkinson :-

1- amantadine

39. antiviral used for influenza and , Parkinson: ( came twice )

a-amantidine

b-lamuvidine

c-zidovudine
40. 19-used for HIV&HIB :-
1-Lamivudine
2-stavudine
3-amantadine

41. In AIDS the CD4 less than:-

a-200
b-400
c-500
d-600

42. CD4 bind to which antigen in the HIV positive Pt:-

a-T lymphocyte
b-B lymphocyte

43. case scenario about patient HIV and have low fever and lung diffuse
and ask which negative myco bacterium like to cause this infection : 
Mycobacterium avium complex

44. TB. medication ,INH,PYZ,RMP ,which is the SE. of INH ( came as a

case ) :

1-peripheral neuropathy
2-nephrotoxicity
45. Which is not true about immune reconstitution inflammatory
syndrom :
1) corticosteroids and anti - inflammatory drugs don’t shorten inflammation
action .
2) The action of antiviral start when virus load is high .
3) The pt start respond to treatment when CD4 is high

46. Pt in the ICU for 3 days which antacid is used :-

a-PPIs
 47. drug used in IBD(Inflammatory bowel disease) remission:
- infliximab

48. charcoal act by which :-

a-adsorbant
b-absorbant

49. SIADH(Syndrome of inappropriate antidiuretic hormone) cause all of

the following except:-
a-hyponatremia
b-hypernatremia
c-water excess
d-Inadequate vasopressin production

50. MTC means

a-Maximum toxic conc.
b- Maximum safe conc.

51. Cmax stands for:-

a-the maximum conc that drug reach at t time

Tmax stands for:-

52. time at which plasma concentration reach maximum
53. above MTC : toxicity
54. Under MEC : ineffective

55. I n high therapeutic index ( in a case )

c- It is unlikely to show any serious side effects

57 . 10 ml ampoule of 3% drug how many ml required to give 150mg dose?

a-3ml
b-5ml
c-7ml
d-9ml
58. 50% alcohol is to be diluted with purified water, how many parts of
purified water (0% alchohol) to prepare 20% preparation.?
a- 30parts water + 20 parts 50% alchohol

59 . Dose for patient is 75mg, how ml needed from 125mg/5ml solution :

a. 5 ml
b. 3 ml
c. 15 ml

60 . How many gram of 5% ointment will be prepared from 2 gm :

answer.. (5%= 5gm ----100 ,,2gm---?
2*100/5 = 40 gm

61 . How many gram will be in 250 ml of 5% solution :

answer.. 5% = 5gm ---100ml
??--------250ml
= 250 *5 /100 = 12.5 gm

62. If dose of drug is 0.2 ml, How many dose will be in 15ml :
answer.. 15ml /0.2 ml =75 doses

63 . Advantages of IV route over oral route:

1-safe and convenient, rapid onset, dose can be titrated, can be used in ER
2- safe and convenient, can be used in ER
3- rapid onset, dose can be titrated, can be used in ER
4- rapid onset, can be used in ER

64. Foam in pharmacy found as spray is used as:

1-Burn dressing and topical but not for rectal administration
2- Topical and rectal but not for burns
3- Topical, rectal and for burn dressing
4- Topical only
65 -which is true about dry gum emulsion:-
a-ratio 4:2:1
b-water gum and oil are added together and triturated slowly
c-oil and gum are triturated and water added slowly.

66. emulsion inversion:

a-conversion of W/O emulsion to O/w emulsion and vice versa

67. Conductivity in emulsion, the dispersed phase for such emulsion is:

1-Aqueous
2- Non aqueous
3- Aqueous and non aqueous

68 . velocity in dispersed phase affected by:-

a-particle size
b-particle homogeneity
c-elecrtic charge
d-all

69 . Conductivity test – Dilution test – Dye test used for which dosage form :
a. Susp.
b. Emulsion
c. Foam
d. Gel

70. Particle size affects:

1-Suspend ability
2- Penetrability
3- Dissolution rate
4- Dose to dose uniformity
5- Uniformity of tablet
6- All of the above

71. Xanax‫ ®آ‬alprazolam (CDA) must store in:

a. Steel cupboard well closed
b. Cupboard opened by 2 person

72. 70 yr old diabetic pt on oral hypoglycemica and suffering from

hypertension ; Which of the following antihypertensive drugs is not
recommended : 
1- losartan
2- enalapril
3- Hydrochlorothiazide
4- Atenolol

73. patient with hypertension put on antihypertensive drug, after few months
developed heart failure manifested as reduction in heart rate and
contraction, which antihypertensive drug patient put on:
a. Lisinopril
b. verpamil
c. prozosin
d. Thiazide diuretic

74. timolol is contraindicated in all the following except

A.HTN
b. Congestive Heart failure
c- Bronchial asthma

75. Beta blocker use in all except:

1-Bronchial asthma

2- hypertension
3- migraine

76. prinzmetal angina:

a-sudden spasm
b-sudden spasm with atherosclerosis
c-sudden spasm with atherosclerosis and not responsive to CCBs and
nitroglycerin
d- sudden spasm ,with atherosclerosis, and respond to CCBs and nitroglycerin
77. which of the following not used in prinzmetal angina??
atenolol
nifedipine
nitroglycerin
dilitazem

78. years old Male patient , he is a smoker and having COPD, which of the
following drugs should be avoided :
A. Digoxin
B. Verapamil
C. Amiodrone ( CHECK PLEASE )
D. lidocaine

79. - Patient just recovered from myocardial infarction 10 days ago and
discharged from the hospital, to prevent recurrence of arrhythmia which
medication is most suitable for him :-

1-verapamil ( check please )

2-quindine

3-sotalol

80 . Common side effects of arrhythmic drug:

torsade de pointe
blurred vision

81. CASE About Arrhythmia ( statements ) :

a-most cause of recurrent arrhythmia due to reentry
b-Most Of them is Calcium and sodium blocker
c-SA node is the pace maker ( something like that )
d.anti-arrythmic safer than operation

82. Patient with arrhythmia given medication that decrease the velocity and
force of contractility which one of this drugs :
a. Verapamil
b. enalapril
83. Mechanism of action of digitalis all true except: 
a - increase contractility
b- decrease vascular resistance 
c- have modify effect on autonomic nervous system
d- maintain ventricular rate in atrial fibrillation

84 . Case Patient with glaucoma and blood pressure 220/110 and hypertensive
crisis and ask which to avoid :-
a-nicardipine
b-fenoldopam
c-Na nitroprusside
d-labetalol

85. patient diagnosed with mild dyslipidemia and decreased HDL , what is the
drug useful in his condition ?
A) Niacin 
B) Clofibrate
C) Cholestyramine 
D) Rousavastatin
86. CI of loop diuretic except:-
renal disease
anuric despite using loop

87. Thiazide diuretic doesn’t cause

1. hypokalemia 
2. hyperuricemia
3. hypocalcemia 
4. Hyponatremia

88. All are route of administration of nitroglycerin except :-

Sublingual

Buccal

oral
89. The role of B-blocker in MI is all of the following except:
a-Decrease mortality and morbidity
b- decrease infract size
c- Increase O2 demand in the heart

90. The cough in ACE inhibitors: EXCEPT:

A. Accumulation of bradykinin
B.In women more than men
C. Appears in 6 months
D. Dose related

91 . which one must be labeled and separated :

epinephrine injection ( epi pen )
nifedipine
sotalol

92 . case about a child had hypersentivity reaction to bee sting :

epinephrine
norepinephrine
atropine

93 . anti glacucoma means :

Drug that decrease asthma
drug that decreses IOP

94. graph : how much time it will stay in body:

24 h
95. how much conc at time 12 :
10ng/ml
20ng/ml
5ng/Ml

96. how much t max : 3 h

97. Primaquine is contraindicated in all of the following except: 
1- SLE,RA 
2- G6PD deficiency 
3- Lactating female 
4- Pregnancy

98 . Ipratropium approved for:

Maintaining COPD

ASTHMA

99. atropine side effects are all of the following except : -

decrease gastric secretion

decrease gut motility

100. How many mg of drug are in 20 g of 1%?

1 gm  100 g

x gm  20 g
x = 0.2 gm = 200 gm