ICNP – 2018 PRODUCTION OF BIOCOMPATIBLE MATERIAL

India USING MAGNETITE AND RICINOLEIC ACID

Silva LV, 1 Moraes RS,1 Souza Jr. FG*,1
1
Instituto de Macromoléculas Professora Eloísa Mano –
IMA/Universidade Federal do Rio de Janeiro - UFRJ, Brazil

e-mail: fgsj@ufrj.br

Introduction Results and Discussion

The nanoparticle of magnetite (Fe2+Fe3+2O4) presents magnetic properties

with applications in several areas such as chemistry, physics, medicine,
catalysis, functional magnetic resonance and environmental remediation.
Ricinoleic acid (12-hydroxy-9-cis-octadecenoic acid), which can be extracted
from castor oil. It is biocompatible and has wide application in the biomedical
areas, with analgesic and bactericidal actions. And Ricinoleic acid can be
converted to a macromolecular material.
In the reaction between the nanoparticle and ricinoleic acid, the acid
attaches to the surface of the magnetite and this allows it to become more
compatible with the human body and can thus be employed as a biomaterial
for, for example, drug delivery systems. Figure 1: FTIR spectra of ricinoleic acid (R.A), magnetite (Mag) and Composite (Comp).

Objective
To extract ricinoleic acid from natural castor oil and makes surface
modification on magnetite nanoparticles with poly (ricinoleic acid) in order to
modify its properties.
Figure 2: Dynamic light scattering size distribution
Experimental of the composite.

Figure 3: Magnetic force of composite.

Conclusion
Ricinoleic acid, magnetite and composite was successfully synthesized as shown
Characterization:
by FTIR results. The particle size was investigated by dynamic light scattering
• Fourier-transform
infrared spectroscopy (FT- showing a fairly narrow size distribution. The magnetic force test showed that the
IR)
composite has good magnetic properties.
• Dynamic Light Scattering
(DLS)
This work was able to synthesize a biocompatible and magnetic material at a

• Magnetic Force
nanometric scale with potential for biomedical applications using materials from
renewable sources.

References
Ferreira, L. P.; Moreira, A. N.; Pinto, J. C.; De Souza, F. G., Polymer engineering and science, v.55, n/a-n/a (2014).
Corcuera, M. A., Rueda, L., Fernandez d’Arlas, B., Arbelaiz, A., Marieta, C., Mondragon, I., & Eceiza, A. Polymer Degradation and Stability, V.95 (11), 2175–2184 (2010).
Guelcher, S. A. Tissue Engineering Part B: Reviews, V.14(1), 3–17 (2008).
Ogunniyi, D. S. Bioresource Technology. V.97, Issue 9, June 2006, Pages 1086-1091
Mutlu H. , Meier, M. A. R. European jornal of Lipid science and Technology.V.112, Issue1. January 2010. Pages 10-30

Acknowledgement