DISPOSABLE PLASTIC SYRINGE

[EIRI/EDPR/4029] J.C.: 2161XL

INTRODUCTION

A Disposable syringe is a basic responding siphon comprising of a plunger

(however in present-day syringes, it is really a cylinder) that fits firmly inside a
round and hollow cylinder called a barrel. For syringe manufacturing plunger can
be directly pulled and pushed along within the cylinder, enabling the syringe to
take in and oust fluid or gas through a release hole at the front (open) part of the
bargain.

The open part of the bargain might be fitted with a hypodermic needle, a spout or
tubing to coordinate the stream into and out of the barrel. Syringes are as often as
possible utilized in clinical medication to control infusions, imbue intravenous
treatment into the circulatory system, apply mixes, for example, paste or oil, and
draw/measure fluids.

Disposable Syringe is an instrument which is used for injecting any liquid into the
body of human beings or of animals. It consists of a cylinder and an air tight
piston. These syringes are used for injecting the medicine into the body or into the
nerve of the body which are not possible to take in through mouth or takes much
time in mixing with blood.

These syringes are available in sizes varying from 2 C.C. to 100 C.C. Most popular
and commonly used sizes are 2 C.C., and 5 C.C. Other sizes are also frequently
used but upto lesser extent.

In this project, we are manufacturing the disposable syringes with the sizes are 2
ml, 5 ml, 20 ml and 50 ml.

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Previously glass was used for making these syringes; the most commonly used
glass is Pyrex glass. This glass is shock-resistant, temperature-resistant and has
low thermal co-efficient of expansion. But with the development of plastic
technology, this glass has been substituted by high grade plastics. Plastic can be
used in place of glass for making syringes without any problem.

Plastic syringes are becoming more popular in the medical world due to its lower
cost and higher accuracy. To test the efficiency of a syringe, close the tip with a
finger and attempt to withdraw the plunger or piston. If the plunger and barrel fit
perfectly, the vacuum created in the cylinder will prevent withdrawal of the
plunger. The plunger should not be pulled to return rapidly due to the vacuum
created or the barrel may be cracked.

With the development of pharmaceutical industries the use of syringes has also
developed. About 70% pharmaceutical industries are in small scale sector. The
output of the small scale sector covers a wide spectrum of formulations, which
includes antibiotics vitamins, anti T.B. drugs, ant dysentery drugs, anti-
rheumatics, haematinies, hormonal preparations, tranquilizers, analgesics and
anti-phyreties. Indeed this is a very wider range of product mix. About 50 percent
of the above listed drugs are injectable and for that purpose syringes are required.
Disposable Syringes are being used by doctors to inject medicines through
intravenous or intramuscular ways for the treatment of diseases & also by
research & development personnel. Disposable syringes are made of plastic
material and are used in the field of medical and veterinary science. Due to their
availability in sterilized condition, ready to use, and cost effectiveness, disposable
syringes are fast replacing the age-old glass syringes. Moreover, the horror of AIDS
worldwide has almost dispensed with the reuse of syringes and the demand of
disposable syringes has increased phenomenally. Disposable syringes are mostly
injection molded from polypropylene. Syringes are available in sizes of 1 ml, 2 ml,
5 ml and 10 ml, 50ml in a variety of designs and consist of either two or three
components construction. The number and size of injection moulding machines
required depend upon syringe construction, number of mould cavities, annual
production.

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Disposable Syringes made of plastic Material have been successfully used in
medical and pharmaceutical practice for many years. The constantly increasing
use of this type Syringe indicates its importance. Which is based mainly on the
advantages it offers regarding cost and hygienic applications.

The manufacture of plastic syringes has been developed to such a degree that the
products now satisfy the requirements and standards set by Hospital and
physicians. At the same time they offer the best possible technique of application
to the physician and the highest possible degree of safety to the patient.

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 COST ESTIMATION

Plant Capacity 1,50,000 Nos/Day

Land & Building (3000 sq.mt.) Rs. 1.96 Cr
Plant & Machinery Rs. 4.64 Cr
Working Capital for 1 Month Rs. 2.61 Cr
Total Capital Investment Rs. 9.84 Cr
Rate of Return 36%
Break Even Point 15%

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 CONTENTS

INTRODUCTION
PROJECT LOCATION
CITY MAP
GEOGRAPHICAL AND PHYSICAL FEATURES
CLIMATE
TRANSPORTATION
PARTS OF SYRINGES
SYRINGES AND NEEDLES
NEEDLES
VASCULAR ACCESS NEEDLE GAUGE RECOMMENDATIONS
TYPES OF SYRINGES
SELECTING SYRINGES
SYRINGE TIPS
SELECTING NEEDLES
NEEDLE GAUGE
NEEDLE LENGTH
TYPES OF HYPODERMIC NEEDLES
BEVEL
GAUGE
COMMON GAUGES
DISPOSAL OR REUSABLE
USES AND APPLICATION
1. USED FOR EXTRACTION OF BLOOD:
2. USED FOR VACCINATION:
3. USED FOR INJECTING OF INSULIN:
4. USED FOR ADMINISTERING ANAESTHESIA:
B.I.S. SPECIFICATION
RAW MATERIAL & MACHINERY USED
RAW MATERIAL USED
RAW MATERIALS WHICH ARE USED IN THIS BUSINESS
MACHINERY & EQUIPMENTS
PROCESS FLOW CHART
MANUFACTURING PROCESS
LIST OF RAW MATERIAL
MANUFACTURING PROCESS AND SOURCE OF TECHNOLOGY
PP SYRINGES ARE MADE OF:
INSPECTION AND TESTING

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FREEDOM FROM PYROGENIC MATERIAL
TEST FOR ABNORMAL TOXICITY
FREEDOM FROM EXTRANEOUS MATTER
LIMIT FOR EXTRACTABLE MATTER
GENERAL
LIMIT FOR EXTRACTABLE MATERIAL
LUBRICANTS
NOZZLE
GRADUATION POSITION OF SCALE NUMBERING
FLANGE OF BARREL OR FINGER GRIPS
PISTON
DEAD SPACE VOLUM
MAXMUM DEAD SPACE
LEAKAGE TEST
LEAKAGE TEST BETWEEN BARREL AND PISTON
LEAKAGE TESTING
EXPEL AIR.
ACCEPTANCE CRITERIA
PROCEDURE
ACCEPTANCE CRITERIA
THE TEST SHALL BE FOLLOWED AS BELOW:
STERILITY
MARKING OF UNIT CONTAINER
MARKING OF UNIT CONTAINER:
MARKING OF OUTER CONTAINERS:
PACKING:
OUTER CONTAINER
MARKET SURVEY
PRODUCT INSIGHTS
APPLICATION INSIGHTS
DISPOSABLE SYRINGES MARKET TOP KEY PLAYERS
BECTON DICKINSON LAUNCHES A BD INTEVIA 1ML DISPOSABLE AUTO
NJECTOR
DISPOSABLE SYRINGES MARKET DYNAMICS-
ASIA PACIFIC IS EXPECTED TO WITNESS A FASTEST GROWTH IN THE GLOBAL
DISPOSABLE SYRINGES MARKET
MANUFACTURERS OF DISPOSABLE SYRINGE
COMPLETE PLANT SUPPLIERS FOR DISPOSABLE SYRINGES
SUPPLIERS OF RAW MATERIALS
POLYPROPYLENE GRANULES
SUPPLIERS OF THERMOPLASTIC ELASTOMER
SUPPLIERS OF ETHYLENE OXIDE
SUPPLIERS OF PRINTING INK
SUPPLIERS OF PACKING PAPER

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SUPPLIERS OF PACKING BOXES
SUPPLIERS OF PACKING MATERIALS
DISPOSABLE NEEDLE
SUPPLIERS OF DISPOSABLE SYRINGE GASKET
SUPPLIERS OF PLANT AND EQUIPMENTS FOR DISPOSABLE
SYRINGE/TURNKEY CONSULTANTS
INJECTION MOLDING MACHINE
SCREEN PRINTING MACHINE
STETRLIZING MACHINE
AUTOMATIC BLISTER PACKING MACHINE
SUPPLIERS OF EFFLUENT TREATMENT PLANT (ETP PLANT)
RAW MATERIAL PHOTOGRAPHS
POLYPROPYLENE
ETHYLENE OXIDE
PACKING PAPER
RUBBER GASKETS
NEEDLES
PRINTING INK
MACHINERY PHOTOGRAPHS
COMPLETE LINE
SYRINGE PRINTING MACHINE
AUTOMATIC SYRINGE ASSEMBLING MACHINE
PRODUCTION LINE DETAIL PHOTOS
BLISTER PACKING SYSTEM
MORE DETAILS
SYRINGE LOADING MACHINE
PRODUCT PHOTOGRAPHS

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APPENDIX – A:

01. PLANT ECONOMICS

02. LAND & BUILDING
03. PLANT AND MACHINERY
04. OTHER FIXED ASSESTS
05. FIXED CAPITAL
06. RAW MATERIAL
07. SALARY AND WAGES
08. UTILITIES AND OVERHEADS
09. TOTAL WORKING CAPITAL
10. TOTAL CAPITAL INVESTMENT
11. COST OF PRODUCTION
12. TURN OVER/ANNUM
13. BREAK EVEN POINT
14. RESOURCES FOR FINANCE
15. INSTALMENT PAYABLE IN 5 YEARS
16. DEPRECIATION CHART FOR 5 YEARS
17. PROFIT ANALYSIS FOR 5 YEARS
18. PROJECTED BALANCE SHEET FOR (5 YEARS)

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