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Nifedimine
In NCM 207-RLE
OB Gyne Nursing
Submitted to:
Mrs.Rodelie B. Gulle, RN
Clinical Instructor
Submitted by:
BSN 2D – GROUP 5
Available Forms:
Route of administration:
PO (tablet)
o Do not break, crush, dissolve, or divide extended-release
tablets.
o Give without regard to meals (Adalat CC, Nifediac CC should be
taken on an empty stomach).
o Grapefruit products may alter absorption; avoid use.
Sublingual (capsule)
o Capsules must be punctured, chewed, and/or squeezed to
express liquid into mouth.
I. Mode of action:
Inhibits calcium ion movement across cell membranes, depressing
contraction of cardiac, vascular smooth muscle. Therapeutic Effect:
Increases heart rate, myocardial oxygen delivery, cardiac output.
Decreases systemic vascular resistance, B/P.
II. Indication
Artery spasm (Prinzmetal’s variant angina), chronic stable angina
(effort-associated angina). Extended-release: Treatment of hypertension.
OFF-LABEL: Treatment of Raynaud’s phenomenon, pulmonary
hypertension, preterm labor, prevention/treatment of high-altitude
pulmonary edema.
III. Contraindication
V. Nursing Consideration
BASELINE ASSESSMENT
INTERVENTION/EVALUATION
References:
Kizior, R. J., Hodgson, K. J., Hodgson, B. B., & Witmer, J. B. (2016). Saunders
nursing drug handbook.