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Skin Research and Technology 2014; 0: 1–12 © 2014 John Wiley & Sons A/S.

Printed in Singapore  All rights reserved Published by John Wiley & Sons Ltd
doi: 10.1111/srt.12143 Skin Research and Technology

Skin texture aging trend analysis using dermoscopy


images
Y.-H. Choi1, D. Kim1, E. Hwang1 and B. J. Kim2
1
School of Electrical Engineering, Korea University, Seoul, Korea and 2Department of Dermatology, Chung-Ang University College of Medicine,
Seoul, Korea

Background/purpose: To date, the degree of skin damage Result: A dermoscopy image can be automatically analyzed
caused by diverse factors, such as aging and persistent sunlight by extracting skin texture features. We demonstrate aging
exposure, has been evaluated based on the personal experience trends by performing linear regression on these features.
and knowledge of dermatologists because there is no standard Based on this result, a quantitative and objective evaluation of
method for objective evaluation. If a standard method were avail- the skin condition can be provided.
able, patients could obtain more consistent information about Conclusion: We proposed several new skin texture features
their skin condition, and hence perform more effective treatment and developed algorithms to accurately extract them. We ana-
of the skin damage. In this paper, we demonstrate how to estab- lyzed these features and demonstrated their age-related
lish a standard method using dermoscopy images of subjects of change trends by using graphs and charts. We believe that
various ages. We focus on three body parts, specifically the face, our result can be used as a standard method for evaluating
neck, and hands, and extract various skin texture features to degrees of skin damage. Moreover, we believe that our pro-
quantitatively and objectively represent the skin condition. posed method can be applied in various areas, such as perfor-
Method: We construct a model for skin damage evaluation mance evaluation of certain skin products.
based on various skin texture features. To accomplish this objec-
tive, we consider various features from face, neck, and hand Key words: skin texture – skin texture analysis – skin feature
dermoscopy images, including texture length, width and depth, extraction – dermoscopy image analysis
cell area, the number of cells in a fixed region, radius ratio of
inscribed and circumscribed circles of a wrinkle cell, and average Ó 2014 John Wiley & Sons A/S. Published by John
perimeter of a wrinkle cell. In this study, a wrinkle cell represents Wiley & Sons Ltd
the smallest skin region enclosed by textures. We then perform a Accepted for publication 5 January 2014
linear regression for texture features based on subject age.

the outermost part of the human Therefore, evaluation results can differ depend-
S KIN IS
body. It protects the body from infection,
injury, and water loss, while helping regulate
ing on the dermatologist. The degree of skin
damage can be measured based on various fea-
body temperature. Additionally, the skin main- tures, such as texture pattern, skin elasticity,
tains homeostasis and produces vitamin D. Skin and moisture. Among these aspects, skin tex-
performance is impaired with age and visual ture has the most visual effect and can be seen
beauty is lost. This impairment and loss can with the naked eye. A standard metric to evalu-
proceed more quickly because of various fac- ate the skin condition can be established using
tors, such as persistent sunlight exposure, the diverse features of skin texture. In this
smoking, and excessive drinking. Because of its paper, we propose a model for skin damage
visibility and role, considerable attention has evaluation based on diverse skin texture fea-
been given to its condition, and substantial tures captured from dermoscopy images.
efforts have been taken to mitigate skin aging We believe that skin texture patterns and their
and damage progression. detailed shapes are closely related to the degree
To accurately access the skin condition, a of skin damage. Figure 1 presents texture
method to objectively evaluate the skin is patterns from dermoscopy images of subjects of
required. To date, this evaluation has been typi- various ages. As shown in the figure, skin texture
cally performed by dermatologists based on demonstrates some aging-related trends. There-
their personal experience and knowledge. fore, we focus on the quantitative representation

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Choi et al.

of various features extracted from the dermos- est of these five values is Rm. Rz characterizes
copy images. We construct an evaluation model the mean value of the peak-to-valley roughness
that calculates skin age using average skin tex- in each segment. The depth of smoothness, Rp,
ture features that are the most similar to the skin is calculated as the mean distance of every
texture of subjects of the given age. point of the curve from the highest peak. Ra is
Since the 1950s, numerous methods have the most useful international parameter of
been proposed for skin surface topography roughness. To compute Ra, an average line is
analysis (1–9). According to the dimensional generated to run through the center of the pro-
property of the parameters measured, these file; the area in which the profile deviates above
methods can be divided into two categories: and below this line is determined. 3DTA is typ-
three-dimensional topography analysis (3DTA) ically used in clinical investigations of the local
and two-dimensional image analysis (2DIA). effects of cosmetic and medical substances.
3DTA requires skin surface negative or positive However, it requires a relatively long duration
silicon replicas for further analysis by profilom- of replica hardening and measuring time (3, 4);
etry (mechanical, optical, laser, transmission, or moreover, its accuracy can be degenerated
interference). 3DTA mainly involves the follow- when the patient moves or if the replica is sha-
ing roughness parameters: depth of roughness ken during the hardening process. Because of
(Rt), maximal depth of roughness (Rm), mean these concerns, the replica should be handled
depth of roughness (Rz), depth of smoothness and measured by experts.
(Rp), and mean roughness value (Ra) (4, 5, 7–9). 2DIA analysis, on the other hand, does not
Rt is the peak-to-valley roughness of a surface; require silicone replicas of the skin, and it can
a single feature has a significant impact on the quickly acquire a skin surface image. This latter
derived value. The profile length is divided into factor makes the method applicable to the rou-
five equal segments. The peak-to-valley rough- tine detection of skin surface topography. 2DIA
ness is measured in each segment, and the larg- primarily involves two parameters: tau and

(a) (b)

(c) (d)

Fig. 1. Skin texture based on age – (a) Subjects in their 10s, (b) Subjects in their 20s, (c) Subjects in their 30s, (d) Subjects in their 40s.

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Skin texture aging trend analysis

density. Tau is the level of anisotropy; i.e. the To improve accuracy, we proposed line siev-
percentage of furrows oriented in a different ing and morphological region growing methods
direction. The higher this level is, the greater is for calculating texture length and width, respec-
the anisotropy of the surface (7). Density refers tively (17). To acquire additional features, we
to furrow density, which is expressed through proposed a method for estimating texture depth
the occurrence of intersections between primary based on the color difference between texture
wrinkles (5, 7). and non-texture regions. On the other hand,
Fujimura et al. (10) examined the relationships Zou et al. detected the area mean of a superfi-
between roughness values obtained from the cial skin texture block formed by primary and
morphological structure of the corner of the eye secondary lines crossing each other (18).
and age or wrinkle scores using Japanese To evaluate the skin age of subjects, we
women aged 10-70 years in order to demonstrate extracted the texture features from their der-
the practicality of using direct three-dimensional moscopy images and classified them into an
in vivo measurement system (PRIMOS) to age group using a support vector machine
evaluate wrinkles objectively in clinical tests of (SVM) (19).
wrinkle-smoothing ingredients or cosmetic sur- In this paper, we demonstrate the aging
gery. To detect skin wrinkles, Tanaka et al. trends of various skin features, which include
applied a cross-binarization method to a digital texture features, cell information, and radius
skin image to obtain its binary image. A short ratios of inscribed and circumscribed circles of
straight-line matching method was then per- each cell and cell perimeter. We have devel-
formed to detect wrinkles from the binary image oped diverse image processing algorithms to
and to measure their lengths (11). For each base- efficiently extract these age-related features, and
line in the cross-binarized image, if more than we briefly describe in the following section how
70% of its pixels were marked black, then the to extract the features. In the Result and Discus-
line was considered a wrinkle. The end of the sion section, we present statistical values of the
previous baseline was then extended to create a extracted features and their aging trends.
new baseline. This step was repeated until the
end of the wrinkle or image was reached.
Hayashi et al. proposed an age and gender
Material and Methods
estimation method based on the facial image Feature extraction scheme
(12, 13). They first detected wrinkles from a We have developed algorithms for extracting
facial image using a Hough transform called various features from dermoscopy images. Our
the Digital Template Hough Transform (DTHT). feature extraction method consists of three
Hatzis presented a profilometric method for major steps: pre-processing, texture feature
measuring the size and function of the wrinkles extraction, and cell feature extraction. Table 1
(14). The replication was made using silicon rub- shows the detailed tasks performed in each step.
ber similar to dental impression material. The Before performing analysis of these features, we
microtopography of wrinkles in negative replicas made the following assumptions, which are
was photographed by a scanner or stereomicro- based on common knowledge of skin.
scope under suitable lighting to change the nega-
• Texture length decreases with age.
tive appearance of the replica into a positive one.
• Texture width increases with age.
In our previous work, we proposed a scheme
• Texture depth increases with age.
to detect skin texture from dermoscopy images
• Cell area increases with age.
and to estimate texture length and width (15).
• Number of cells decreases with age.
In the scheme, skin textures were detected
• Diameter ratio of inscribed circle and circum-
using the watershed algorithm, which was first
scribed circle of a cell decreases with age.
introduced by Lantuejoul and Beucher for
• Total length of lines connecting cross points
image segmentation (16). The texture length
of a cell increases with age.
was estimated simply by counting the pixels on
the textures. To estimate the texture width, we In our study, we show that our assumptions
proposed a block thickening method. Neverthe- about texture features are reasonable by con-
less, we observed that there is ample capacity structing their related trends using regression
for improvement in these methods. graphs.

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Choi et al.

TABLE 1. Three major steps of feature extraction 152 pixels. Therefore, the relative wrinkle
Step 1. Pre-processing Region of interest (ROI) selection length in the pixel unit can be converted into a
Image normalization real length in millimeters by applying this
Binarization and denoising
Image segmentation relationship.
Step 2. Texture Texture length estimation To measure the length, we use the line siev-
feature extraction Texture width estimation ing method. This method first counts the num-
Texture depth estimation
Step 3. Cell feature Cell detection using PMDA
ber of pixels on the horizontal and vertical
extraction Over-segmented cell merging texture lines. It then counts the number of pix-
Cell area estimation els along the diagonal lines, and it multiplies
Cell counting
their slope to estimate the actual wrinkle length.
Inscribed/circumscribed circle evaluation
Length measurement for line connected In the case of single pixel islands on the image,
between contact points we simply count these islands and add the
number to the total length.
To measure wrinkle width, we must recover
the original wrinkle from its single pixel skele-
Step 1. Pre-processing ton image. For this purpose, we use a morphol-
Due to camera device limitations and light ogy-based region growing method. The method
source interference, captured images may exhi- basically involves applying a dilation process to
bit noise and vignetting. In the pre-processing the wrinkle skeleton to recover its actual width.
step, we remove these effects. Vignetting is a The wrinkle area is identified in the dilated
reduction in brightness or saturation at the region and gradually expanded. During this
periphery of an image compared to the image expansion, we perform a cross-comparison of
center. The luminous source of a digital micro- the output image with the grayscale image to
scope image is typically concentrated around its recover the wrinkle region. This step is repeated
center. Therefore, to remove the vignetting until the comparison fails or succeeds n times,
effect, we first crop a region of interest (ROI) where n is a threshold value for determining
from the image center, where the luminance is noise. That is, if the number of expanded pixels
the most homogeneous. We set its size to is smaller than n, we consider it a noise. Equa-
300 9 300 pixels, which empirically provides a tion 1. Depth measurement:
minimal vignetting effect. Nevertheless, the 1 Xn
cropped image may contain slight vignetting. DðIk Þ ¼ maxðjIk ðSÞ  Ik ðci ÞjÞwhere
n i¼1
Therefore, we apply a gradation masking 1
method to remove the vignetting residue. In js  ci j ¼ avgwidth þ margin s.t.8s 2 Si ; 8ci 2 C
2
addition, we apply a contrast equalization
ð1Þ
method to improve the contrast in the cropped
image. To eliminate noise in the image, we first Careful investigation of skin images reveals
binarize the image using Otsu’s method and that the color of wrinkle regions is darker than
perform the denoising algorithm. To obtain the normal skin texture. Furthermore, depending
skeleton image, we apply a watershed algorithm on the depth of the wrinkle regions, their
to the binarized image, which produces a single degree of darkness can differ because of light
pixel line along the center of the skin texture. interference. Based on this difference, we esti-
mate relative wrinkle depth using Eq. 1. In the
equation, C represents a set of n randomly
Step 2. Texture feature extraction chosen points along the skeleton line of a
In this step, we extract from the skeleton image wrinkle. For each point ci in C, we first iden-
diverse skin texture features, such as length, tify set Si of all points whose distance from
width, and depth. We first estimate the length point ci is r. We then calculate the maximum
by counting the pixels on the wrinkle texture, color difference between points in Si and ci.
which provides relative length. We convert the Distance r can be defined as half the average
measurement into a real length using an SI width + the margin. Finally, if we add the
unit. The idea is simple; a 1-mm line maximum color differences of all points in C,
enlarged by a 609 magnifier, which is used to their average becomes the depth of the wrinkle
capture dermoscopy images, corresponds to region.

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Skin texture aging trend analysis

Step 3. Cell structure


Typical skin images reveal that skin texture is
composed of regions separated by wrinkles
called wrinkle cells. Boyer et al. (21) showed that
the skin of younger people has more cells in the
skin wrinkle image than that of older people.
Based on this observation, we propose a Poly-
gon Mesh Detection Algorithm (PMDA) for cal-
culating the number of cells and the average cell
area. This algorithm works in a recursive way.
Using numerous dermoscopy images of subjects
of various ages, we observed that the number of
cells and the average cell area are closely related
to subject age. We also found that as people age,
their skin cells enlarge with wider wrinkles. Fig. 2. PMDA image.

Algorithm 1 degrade the accuracy. Therefore, if the size of a


PMDA cell is not sufficiently large, we do not consider
Procedure: PMDA it. Algorithm 2 outlines detailed steps to con-
Input: binary skeleton image S,
boolean image B, struct a cell map to efficiently run PMDA. The
current position (x,y)
Output: current cell size A
algorithm first initializes the map with the skel-
1: B(x,y) := false eton image and enqueues all random coordi-
2: A:=1
3: for each adjacent points p(x’,y’)
nates. The algorithm then dequeues the random
4: if B(x’,y’) == true coordinates and calls the PMDA algorithm for
5: A=A+PMDA(S,B,(x’,y’))
6: end if cell detection.
7: end for
8: return A

Algorithm 2
Cell Map Construction Algorithm
Algorithm 1 outlines detailed PMDA steps. Procedure: Cell Map Construction Algorithm
As mentioned above, the skin image is repre- Input: binary skeleton image S
Output: average area Aavg, total cell count Ccell,
sented by a skeleton graph using the watershed fully enclosed cell count Cfcell
algorithm. For example, in Fig. 2, polygons are 1: for each pixel p(x,y) in boolean image B
2: if S(x,y) == 0
separated by skeleton lines, and each polygon 3: B(x,y) := false
represents one wrinkle cell. To obtain the num- 4: else
5: B(x,y) := true
ber of cells and the dimension of each cell, we 6: end if
7: end for
use a connected component detection method. 8: Ccell :, Cfcell , Atotal := 0
The method recursively searches for four neigh- 9: enqueue randomly all position pairs (x,y) in B into queue Q
10: while Q != empty
bors (top, down, left, and right) from the start 11: (x,y) := dequeue Q
point until a wrinkle line or image boundary is 12: if B(x,y) == true
13: (A,CAB) := PMDA(B, (x,y))
encountered. If an image boundary is met, we 14: Ccell := Ccell + 1
15: if CAB == false
then increase the total cell count and mark the 16: Cfcell := Cfcell + 1
cell as a border cell. We use the total cell count 17: Atotal := Atotal + A
18: else
as a feature; however, when we calculate the 19: if (A / border distance) < RatioD
average cell area, we divide the total area by 20: Cfcell := Cfcell + 1
21: Atotal := Atotal + A
the number of complete cells, which excludes 22: end if
23: end if
the border cells. If an image boundary is met, 24: end if
we then check whether the size of the cell is 25: end while
26: Aavg := Atotal / Cfcell
meaningful. If it is meaningful, we consider it a 27: return Aavg, Ccell, Cfcell
complete cell and count it. Otherwise, we dis-
card the cell. Because our scheme uses a small
segment of the image, incomplete cells, which Cell features are crucial for accurately evalu-
are border cells, could exist. Those cells tend to ating skin texture. However, at times cells turn

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Choi et al.

(a) (b)

Fig. 3. Detected over-segmented and merged cell image – (a) Convex hulls and over-segmented cells, (b) Merged cell image.

Fig. 4. Detected inscribed/circumscribed circles.

(a) (b)

Fig. 5. Average connected-line length measurement – (a) Detected contact points, (b) Connected contact points.

out to be over-segmented for various reasons, cells should be eliminated before feature extrac-
such as light source reflection and shadows. tion. In this part, we describe our method for
Therefore, for better accuracy, over-segmented detecting over-segmented cells in the skeleton

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Skin texture aging trend analysis

Fig. 6. User interface.

skin image and for removing them by merging ing, we maintain three lists: detected cell, over-
them with neighboring cells. segmented cell, and merged cell. The detected
To detect over-segmented cells in the skeleton cell list contains diverse information about cells
image, we construct a convex hull for each cell. in the image. The over-segmented cell list
The convex hull represents a cell by using a maintains all over-segmented cells with their
minimum set of points connected with straight neighboring cell. Finally, the merged cell list
lines. After constructing a convex hull for each contains information about merged cells.
cell, we check whether there are any cells For each over-segmented cell pair in the list,
whose center points of gravity are inside we first check whether the area of the inner cell
another cell’s convex hull. If so, we consider the is less than the average cell area. If it is, we
cell to be over-segmented. For example, merge the inner cell into the outer cell. This
Fig. 3(a) shows convex hulls constructed for the information is recorded in the merge cell list.
wrinkle cells in the sample image. Over-seg- The merge cell list will eventually contain all
mented cells are marked in blue. merged cells. Finally, we update the detected
After detecting all over-segmented cells, we cell list based on the merged cell list to obtain
eliminate them by merging. For efficient merg- the final set of cells. For example, Fig. 3(b)
shows the result of merging over-segmented
cells for the image in Fig. 3(a). After cell merg-
Algorithm 3 ing, we calculate the new contour and area of
Contact point detection the merged cells. We also adjust the average
Procedure: ContactPointDetection cell area and cell count.
Input: binary skeleton image S(x,y) To extract inscribed/circumscribed circles of
Output: contact point contactPoints CP
1: for each point p(x,y) in S(x,y) a wrinkle cell, we use the morphological region
2: cnt = 0 growing method. The method starts from the
3: for each adjacent points padj(x,y)
4: if padj(x,y) is not equal with adjace gravity center point of the cell and grows the
5: cnt++
6: end if
region until it meets the wrinkle contour. The
7: end for method records the coordinates of first and last
8: if cnt >= 6
9: insert p(x,y) into contactPoints CP meeting points.
10:
11: end for
end if The first meeting point becomes the radius of
the inscribed circle, and the last meeting point

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Choi et al.

becomes the radius of the circumscribed circle. three or more wrinkle lines meet. As shown in
Finally, we calculate their radius ratio. We later Fig. 5(a), all contact points are marked in red.
use the top 15 ratios for skin-aging trend analy- To determine the contact points, we individu-
sis. As shown in Fig. 4, inscribed and circum- ally consider each wrinkle pixel, and we search
scribed circles are represented as bold and thin the pixel along eight adjacent neighbors. Cir-
lines, respectively. cling from the top pixel of the current point to
Finally, we calculate the total length of all the right side, the algorithm searches for the
lines connecting the wrinkle line contact points color changing point. The color changing point
on the cell. A contact point is the point where is where the adjacent two points have differing

Fig. 7. Face skin texture aging trend.

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Skin texture aging trend analysis

color values. If there are four color changing


Result and Discussion
points, the current point is on the skin texture,
and the scheme proceeds to the next point. Experimental setup
However, if there are six color changing points, Above, we have described our scheme for
then there are three texture lines, and the cur- extracting various skin texture features from
rent point is the contact point. Therefore, the dermoscopy images. Based on this scheme,
algorithm detects if there are six or more points. we have implemented a prototype system and
This detecting contact point procedure is performed various experiments to determine
explained in Algorithm 3. Figure 5(b) exempli- skin-aging trends. Figure 6 shows the user
fies a connection of all the contact points based interface of our prototype system. As men-
on the original skeleton image. tioned earlier, we used a 300 9 300 pixel image

Fig. 8. Neck skin texture aging trend.

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Choi et al.

at the center of the image to avoid the vignett- aging trends. We again extracted seven texture
ing effect. We have constructed a dataset of features, including skin texture length, width
face, neck, and hand dermoscopy images from and depth, average cell area, cell count, radius
approximately 200 subjects. We then grouped ratio of inscribed/circumscribed circles, and
them into five classes depending on subject age. average length of lines between contact points.
The first graph in each of these figures shows
the distribution of total lengths of skin textures
Feature extracting result in the respective image and their linear regres-
Figures 7–9 show skin texture features of each sion. From information in these graphs, it is evi-
subject and the overall face, neck, and hand skin- dent that the total length of skin texture

Fig. 9. Hand skin texture aging trend.

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Skin texture aging trend analysis

TABLE 2. Analytic results of statistical values (face)

Avg. of total Avg. texture Avg. depth Avg. cell Avg. of total Avg. radius Avg. length
length (mm) width (pixel) (color diff.) area (pixel) no. of cells (count) ratio (ratio) of lines (mm)

10s 36.09 7.97 111.12 903.77 88.12 0.5456 0.1601


20s 33.42 8.04 113.50 1021.01 77.15 0.5322 0.1661
30s 30.41 8.51 115.03 1124.576 68.06 0.5203 0.1695
40s 29.94 8.81 121.86 1312.821 63.46 0.5146 0.1699
50s 28.25 8.99 120.91 1710.794 60.75 0.5120 0.1721

TABLE 3. Analytic results of statistical values (neck)

Avg. of total Avg. texture Avg. depth Avg. cell Avg. of total Avg. radius Avg. length
length (mm) width (pixel) (color diff.) area (pixel) no. of cells (count) ratio (ratio) of lines (mm)

10s 36.57 9.79 116.64 882.27 91.44 0.5672 0.1655


20s 34.43 10.57 118.81 997.20 80.20 0.5564 0.1755
30s 33.07 11.40 118.09 1151.77 73.83 0.5400 0.1787
40s 32.51 11.95 126.22 1153.29 73.25 0.5368 0.1805
50s 31.83 12.08 125.75 1230.70 70.91 0.5310 0.1835

TABLE 4. Analytic results of statistical values (hand)

Avg. of total Avg. texture Avg. depth Avg. cell Avg. of total Avg. radius Avg. length
length (mm) width (pixel) (color diff.) area (pixel) no. of cells (count) ratio (ratio) of lines (mm)

10s 26.81 9.87 117.52 1418.32 52.09 0.5145 0.1930


20s 23.45 11.49 118.60 1700.91 42.38 0.5033 0.2065
30s 21.08 11.89 118.48 2425.09 35.50 0.4952 0.2123
40s 20.04 13.07 127.86 2680.59 32.73 0.4899 0.2232
50s 18.33 13.99 127.26 2741.33 28.80 0.4514 0.2352

decreases with age. Another interesting obser- the number of contact points decreases and
vation is that the average cell count decreases the average length of lines increases. This ten-
with age and the cell area increases. In fact, dency is explained by the fact that wrinkle
these observations are closely related to each cells enlarge with age. As the cell size
other. Because the cell size increases, both the increases, there are fewer cells in the image.
number of cells in the region and the total tex- Therefore, the number of contact points
ture length decrease. decreases and the line connecting them length-
Another feature of interest is texture width ens. Because of this tendency, the graph shows
and depth. We generally believe that wrinkles an increasing trend.
become wider and deeper with age. The graphs Tables 2–4 show the average value of each
in Figs 7–9 clearly show this trend. texture feature for the five age groups: 10s,
The next feature that we evaluate is the 20s, 30s, 40s, and 50s. The tables show a simi-
radius ratio of inscribed/circumscribed circles. lar trend as the graphs in Figs 7–9.
We consider this feature because it is commonly
believed that skin texture becomes stretched in
one direction with age. In fact, as cells become
Conclusion
stretched, their circumscribed circles enlarge. In this paper, we proposed a scheme for skin tex-
As a result, the radius ratio decreases. The ture aging trend analysis in terms of diverse skin
graph is well matched to our analysis. In the texture features. We considered several features,
graph, we used the top 15 ranked ratios among including skin texture length, width and depth,
the cells in the image because they showed this the number of cells and their average areas, the
tendency very well. radius ratio of inscribed/circumscribed circles,
The last feature we consider is the number and the length of lines between contact points.
of contact points and the average length of The feature trend graphs are well matched with
lines connecting them. According to the graph, what is typically understood about skin texture.

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Choi et al.

For example, with age, wrinkle cells enlarge and


Acknowledgements
skin cell count decreases. In sum, a single two-
dimensional dermoscopy image contains abun- This research was supported by the MSIP(Min-
dant information for estimating skin texture istry of Science, ICT and Future Planning),
aging, and our proposed scheme is highly effec- Korea, under the IT/SW Creative research pro-
tive in achieving this estimation. Our scheme can gram supervised by the NIPA(National IT
be used for establishing a standard method for Industry Promotion Agency) (NIPA-2013-
measuring the degree of skin damage or aging. H0502-13-1119).
We expect that our scheme can be used in vari-
ous commercial and non-commercial skin-
related applications.

References 8. Lagarde JM, Rouvrais C, Black D. 16. Beucher S, Lantuejoul C. Use of


Topography and anisotropy of the watersheds in contour detection.
1. Purba MB, Kouruis-Blazos A, skin surface with ageing. Skin Res In Proceedings of the International
Wattanapenpaiboon N, Lukito W, Technol 2005; 11: 110–119. Workshop on Image Processing,
Rothenberg E, Steen B, Wahlqvist 9. Ilive D, Hinnen U, Elsner P. Skin Real-time edge and motion detec-
ML. Can skin wrinkling in a site roughness is negatively correlated tion/estimation, Rennes, France,
that has received limited sun expo- to irritation with DMSO, but not (September 1979).
sure be used as a marker of health with NaOH and SLS. Exp Derma- 17. Kim K, Choi Y, Hwang E. Wrinkle
status and biological age? Age tol 1997; 6: 157–160. feature-based skin age estimation
Ageing 2001; 30: 227–234. 10. Fujimura T, Haketa K, Hotta M, scheme. In Proceedings of the Int’l
2. Nita D, Mignot J, Chuard M, Sofa M. Kitahara T. Global and systematic Conference on Multimedia and
3-D profilometer using a CCD linear demonstration for the practical Expo, New York, USA, (June
image sensor: application to skin usage of a direct in vivo measure- 2009).
surface topography measurement. ment system to evaluate wrinkles. 18. Zou Y, Song E, Jin R. Age-depen-
Skin Res Technol 1998; 4: 121–129. Int J Cosmet Sci 2007; 29: 423–436. dent changes in skin surface
3. Fischer TW, Wigger-Alberti W, Els- 11. Tanaka H, Nakagami G, Sanada H, assessed by a novel two-dimen-
ner P. Direct and nondirect measure- Sari Y, Kobayashi H, Kishi K, Ko- sional image analysis. Skin Res
ment techniques for analysis of skin nya C, Tadaka E. Quantitative Technol 2009; 15(4): 399–406.
surface topography. Skin Pharmacol evaluation of elderly skin based on 19. Choi Y, Tak Y, Rho S, Hwang E.
Appl Skin Physiol 1999; 12: 1–11. digital image analysis. Skin Res Skin feature extraction and proces-
4. Lagarde JM, Rouvrais C, Black D, Technol 2008; 14: 192–200. sing model for statistical skin age
Diridollou S, Gall Y. Skin topography 12. Hayashi J, Yasumoto M, Ito H, estimation. Multimed Tools Appl
measurement by interference fringe Koshimizu H. Age and gender esti- 2013; 64(2): 227–247.
projection: a technical validation. mation based on wrinkle texture 20. Burges CJC. A tutorial on support
Skin Res Technol 2001; 7: 112–121. and color of facial images. Int Conf vector machines for pattern recog-
5. Akazaka S, Nakagawa H, Kazama Pattern Recognit 2002; 1: 405–408. nition. Data Min Knowl Discov
H, Osanai O, Kawai M, Takema Y, 13. Hayashi J, Koshimizu H, Hata S. 1998; 2: 121–167.
Imokawa G. Age-related changes Age and gender estimation based 21. Boyer G, Laquieze L, Le Bot A,
in skin wrinkles assessed by a on facial image analysis. KES 2003; Laquieze S, Zahouani H. Dynamic
novel three-dimensional morpho- LNAI 2774: 863–869. indentation on human skin in vivo:
metric analysis. Br J Dermatol 14. Hatzis J. The wrinkle and its mea- ageing effects. Skin Res Technol
2002; 147: 689–695. surement: a skin surface profilo- 2009; 15: 55–67.
6. Leveque JL, Querleux B. SkinChip, metric method. Micron 2004; 35:
a new tool for investigating the 201–219.
skin surface in vivo. Skin Res Tech- 15. Choi Y, Kim K, Hwang E. Address:
nol 2003; 9: 343–347. WASUP: A wrinkle analysis A E. Hwang
7. Edwards C, Heggie R, Marks R. A using microscopic skin image. Pro- School of Electrical Engineering,
study of difference in surface ceedings of Int’l Conference on Korea University, Seoul, Korea
roughness between sun-exposed Ubiquitous Information Technolo- Tel: +82 2 3290 3784
and unexposed skin with age. gies & Application, Hochiminh, Fax: +82 2 921 0544
Photodermatol Photoimmunol Pho- Vietnam, (December 2008). e-mail: ehwang04@korea.ac.kr
tomed 2003; 19: 169–174.

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