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The Effect of Dorsata Honey on Total Cholesterol and

Plasma LDL Level in Hypercholesterolemic Patients


dr. Zuhriana K. Yusuf, M. Kes, dr. Nanang Roswita Paramata, M. Kes, dr. Sitti Rahma

Medical Departement, Gorontalo State University, Indonesia.

Data analisis :

Introduction • Shapiro wilk


• Paired T. Test
Normal distribution test
Difference total cholesterol
Cholesterol Consuption and plasma LDL level
Genetic
between before and after
giving dorsata honey
• Unpaired T. Test Analisis between
treatmen group &
Cholesterol total
Hypercholesterolemic Atherosclerosis
Plasma LDL control group

Result
Mordibitas & Effect of Dorsata Honey on Decreasing
Mortalitas PJK total Cholesterol LDL plasma
Non
Farmacology Therapy Farmacology Therapy

Dorsata Honey
• Wali (2004) Cholesterol 75 mg
Source : Primary Data 2015
Consume honey every day
• Yaghoubi et. all (2008) Honey Differences in the effect of therapy (treatment)
PJK Risk
• Composition :
and without therapy (control) on the reduction
- Fruktosa 38% of total cholesterol
- Glukosa 31%
- Macronutrien & Micronutrien
- Antioksidan : Fenol acid, Flavonoid dll.

Aims : To determine the effect of anti-oxidants dorsata


honey on level of total cholesterol and LDL plasma in
patients with hypercholesterolemia. Source : Primary Data 2015

Methodology Conclusion
Research Design : True experimental-pre and post test only The dorsata honey antioxidant effect on the levels
Control group design of total cholesterol and plasma LDL levels ini
Population : Hypercholesterolemic patients in gorontalo hypercholesterolemia patients.
Province
Sample : 34 Responden purpossive sampling
Induction criteria : - age 30-60 year References
1. Murray.R.K., Granner, and Rodwell. Biokimia Harper. Penerjemah: Andry Hartono. Buku
- no drug antihipercholesterol Kedokteran EGC. Jakarta. 2009:225-249
2. Sudha MR, Chauhan P, Dixit K, Babu S, Jamil K. Probiotics as complementary therapy for
hypercholesterolemia. Biol Med.2009; 1(4):1−13.
Research Plot 3. Grundy SM, Cleeman JI, Merz CN, Brewer HB Jr, Clark LT, Hunninghake DB, et al.(2004).National
Heart, Lung, and Blood Institute. American College of Cardiology Foundation; American Heart
Association. Implications of recent clinical trials for the National Cholesterol Education Program
Adult Treatment Panel III guidelines. Circulation. 2004;110:227-39
Treatment group Control group 4. Grundy SM. Nutrition in The Management Of Disorders Of Serum Lipids and Lipoproteins. In:
Rusilanti. Kolesterol Tinggi Bukan Untuk Ditakuti. Cetakan Pertama. Jakarta: FMedia (Imprint
Agromedia Pustaka) 2014; 17
10ml honey + 200ml water No intervensi 5. Ariantari N.P., Yowani S. G., Swastini D. A. (2010). “Uji Aktivitas Penurunan Kolesterol Produk
Madu herbal Yang Beredar di Pasaran Pada tikus Putih Diet Tinggi Lemak”. Dalam Jurnal Kimia. 4(1),
Twice a day, during 15 day 15 – 19.
6. Robbins dan Kumar. 1995. Buku Ajar Patologi 1. Edisi 4. Jakarta. EGC. 290- 293
7. Waili. (2004). Natural honey lowers plasma glucose, C-reactive protein, homocysteine, and blood
Measured cholesterol total & LDL level lipids in healthy, diabetic, and hyperlipidemic subjects: comparison with dextrose and sucrose.
Diunduh di http://www.ncbi.nlm.nih.gov/pubmed/15117561. Diunduh pada tanggal 2 April 2014
First day and after 15 days

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