Septic shock Vancomycin Nontyphoidal salmonellosis (NTS)

Plus Preemptive treatment Ciprofloxacin

Antipseudomonal betalactam Severe gastroenteritis
(piperacillin tazobactam, meropenem Bacteremia Ceftriaxone
or cefepime) Meningitis
Meningitis Vancomycin plus Localized infection
Endocarditis Ceftriaxone
Cns abscess Vancomycin plus Leptospirosis
Ceftriaxone plus Mild Doxycycline
Metronidazole Mod-severe Penicillin
CAP With rickettsial dse Doxycycline
Cap – outpatient (without comorbid) Azithromycin
Cap – outpatient (with comorbid, Levofloxacin UTI
antibiotic hx 3mos, macrolide Uncomplicated UTI TMP SMX
resistance) Uncomplicated pyelonephritis Ciprofloxacin
Inpatient, non-icu Ceftriaxone plus UTI (pregnant) NAC Nitrofunantoin
Azithromycin Ampicillin
Inpatient, icu B-lactam plus Cephalosporinove
Azithromycin or quinolone Pyelonephritis (pregnant) Betalactam
Pneumonia-pseudomonas Piperacillin tazobactam Avoid:
Antipseudomonal betalactam Sulphonamides- kernicterus
Ca-mrsa Linezolid or vancomycin Floroquinolone – effect on fetal
Hcap Ceftriaxone cartilage
Hcap-mdr Ceftazidime plus
Gentamicin plus
Linezolid
Hospital acquired Cefepime plus
Flouroquinolone

Mild-mod intra abdominal Cefoxitin

High-risk intraabdominal Carbapenem
Skin and soft tissue Dicloxacillin

Gonorrhoea Ceftriaxone plus

Azithromycin
If reexposed Repeat tx
If not reexposed Metronidazole H Neuropathy, vit b6 pyridoxine def
M. Genitalum Moxifloxacin R Autoimmune thrombocytopenia
Z Gouty arthritis
Trichomoniasis Metronidazole E Optic neuritis (not hepatotoxic unlike hrz)
Bacterial vaginosis (gardnella)
Candidiasis Fluconazole Streptomycin Fetal CN 8 damage
Ulcerative vaginitis (tss) Clindamycin cream
Mpc Gonorrhea - ceftriaxone plus
Azithromycin
M. Genitalum – azithromycin
Resistant - moxifloxacin

Herpes Acyclovir
Syphilis Benzanthine penicillin
Chancroid Ciprofloxacin

Proctitis, proctocolitis, enterocolitis, Empiric:

enteritis Ceftriaxone plus
Doxycycline

Watery diarrhea without distressing Oral fluids and saltine crackers

s/sx
Watery diarrhea with Bismuth subsalicylate or
Distressing s/sx Loperamide (do not use if with fever)
Watery diarrhea >2/d Antibacterial plus
Loperamide
Bloody dysentery Antibacterial
Vomiting, min diarrhea Bismuth
Prophylaxis for traveller’s diarrh

Tetanus Metronidazole
Spams Chlorpromazine, phenobarb
<7 – Dtap
7-9 – Td
>9 - Tdap

Enteric fever:
Empiric and MDR Ceftriaxone
Fully susceptible Ciprofloxacin
Chronic Carriage (CANT) Ciprofloxacin
Amoxicillin
Norfloxacine
TMP SMX