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PHARMACOTHERAPEUTICS EDUCATIONAL ASSIGNMENT

PATIENT EDUCATION
PT NAME. AGE:
Patrick Eric, 27 years
NAME OF MEDICATION
Azithromycin
DOSAGE, ROUTE & FREQUENCY
500 mg orally, start dose, then 250 mg orally daily for four days
INDICATION/DIAGNOSIS
Community-acquired pneumonia (CAP)
POSSIBLE ADVERSE REACTIONS:
Diarrhea, nausea, and abdominal pain.
HEALTH PROMOTIONS RELATED TO DIAGNOSIS AND MEDICATION
Education of the public on the causes of pneumonia and routes of transmission. It includes
information on the need to ensure the annual taking of influenza vaccine, avoid coughing, and
ensure adequate treatment for all respiratory disorders. And to prevent antibiotic abuse, ensure
they see a doctor as soon as possible rather than commence antibiotics by purchasing over the
counter.

CLINICAL INFORMATION
MECHANISM OF ACTION
It acts by covalently binding to the ribosome's 50S subunit in an organism where it is potent.

Thus, interrupting protein synthesis. [ CITATION Aki19 \l 1033 ]

CONTRAINDICATION:
Persons with a history of allergy to any macrolide or a member of the ketolide, including

reports from the earlier administration of azithromycin. It is also contraindicated in patients

taking any member drug of first-generation antipsychotic agents[ CITATION Zac20 \l 1033 ].
WARNINGS/PRECAUTIONS:
Patients on azithromycin need to have liver function accessed. Abnormal findings must be

taken seriously, and drugs discontinued[ CITATION Zac20 \l 1033 ].

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Prolonged use has also been associated with the onset of Clostridium difficile associated

diarrhea (CDAD).
INTERACTIONS:
Interactions have been reported when coadministered with nelfinavir.

It has also been shown to significantly potentiate the effects of oral anticoagulants such as

warfarin, hence considering alternative drugs. When indicated, dosing may be adjusted, and

the patient strictly monitored.

SPECIAL POPULATION CONSIDERATIONS:
No risk has been associated with its use in pregnancy. However, some adverse effects have

been reported in breastfeeding mothers' infants, b not severe[ CITATION Aki19 \l 1033 ]. It is

therefore recommended that breastfeeding mothers must monitor their babies effectively if still

on azithromycin.
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Works Cited
Ito, Akihiro, et al. "Azithromycin combination therapy for community-acquired pneumonia:

propensity score analysis." Scientific Reports 9 (2019): 18406.

Sandman, Zachary and Omar A. Iqbal. Azithromycin. Treasure Island (FL): StatPearls

Publishing, 2020. Internet.