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Description
1. SPECT is a widely available noninvasive functional imaging technique that evaluates cerebral
vascular supply. A radioactive tracer is administered by inhalation or injection into the
bloodstream; the tracer then decays to emit only a single photon. It uses a rotating camera to
track the single photons emitted from radioactive decay and collects information from multiple
views. Evaluation of the radioactive tracers creates images that show cerebral blood flow in
various regions of the brain.
2. The radioactive tracer compounds used are commercially prepared and do not require the
specialized equipment used in PET scanning.
3. SPECT is typically used to evaluate cerebral blood flow in patients with ischemic stroke,
subarachnoid hemorrhage (SAH), migraine, dementia (including Alzheimer’s disease), epilepsy,
and other degenerative diseases.
4. Advantages of SPECT: Can perform hemodynamic, chemical, and functional imaging; widely
available. 5. Disadvantages of SPECT: Ionizing radiation, provides only relative measurements.