Professional Documents
Culture Documents
AUTHORS
to vascular access device (VAD) care and management is imperative to ensure safe and
efficacious patient care. The following challenges were evidenced through literature
patient safety.4-7
• Complexity of patient care includes multiple transitions of care and settings,8 and is
complicated by a myriad of VAD care products selected uniquely for each setting.
• Outcome data is essential and must be collected, analyzed, and utilized to change clinical
Health care organizations must be prepared to address lack of standardization in VAD care and
management. It is essential that each organization (1) develops policies and procedures to align
VAD care and management with recognized standards of practice; (2) integrates unique aspects
of organization-selected VAD care products into policies and procedures and establishes
expectations for adherence to these organizational directives; (3) develops a framework for
gathering and analyzing clinical data related to patient outcomes for VAD care and management;
(4) utilizes quality outcome data to facilitate evidence-based best practices within the
organization; and (5) evaluates and facilitates educational programming to validate clinician
competency.
1
BACKGROUND AND SIGNIFICANCE
VADs are widely used in a variety of clinical settings to infuse solutions and
medications, obtain blood samples, monitor hemodynamic status, and perform therapeutic
phlebotomy and other therapies. The term vascular access refers to cannulation into the vascular
system either through the venous or arterial approach with the cannula tip dwelling peripherally
or centrally. The term VAD refers to all types of vascular access devices; CVAD refers to devices
that are exclusively central vascular access devices. Core elements of care and management are
and standardizing CVAD insertion practices. These efforts have reduced CLABSIs in the United
States by 50% during the last 20 years.1 A meta-analysis of the literature from 1990 to 2015
showed that implementation of VAD insertion and/or management bundles reduced CLABSI in
critically ill patients of all ages.2 Sustained reductions in CLABSI rates over a 14-month period
in 30 long-term, acute care hospitals were demonstrated after implementing a team for CVAD
care, adopting a new product for needleless connector disinfection, and auditing compliance of 6
bundle elements.3
Despite these improvements with a bundled practice approach, infections and other
complications related to inconsistent VAD care and management continue to threaten patient
safety. Variation in VAD care and management practices are widely reported; experts assert that
variation in practice is largely due to a lack of well-designed qualitative and quantitative research
to inform clinical practice.4-7 Standardizing practice for care and management is further
2
practices, and the variables presented in each health care organization. Patient care is managed in
a variety of settings often with multiple transitions between acute care, alternative care, and
home care settings. Accordingly, care coordination and practice standardization have become
These challenges provide organizations the opportunity to develop VAD policies and
procedures that adhere to recognized standards of practice while integrating information and
instruction of VAD care products unique to each care setting. Additionally, clinical practice must
be informed through outcome data obtained within the organization. Frameworks for obtaining,
analyzing, and applying these data for policy and procedure development are needed to improve
INS receives frequent queries from clinicians requesting guidance on VAD care and
management procedures. In response, INS convened a task force charged with the following
responsibilities: (1) review and analyze current VAD-related literature and associated national
guidelines and standards of practice; (2) outline clinical practice recommendations according to
evidence reviewed; and (3) offer tools for VAD care and management, data collection, and
The task force consisted of registered nurses who are experts in infusion therapy and
practice in a variety of clinical settings. Each member was either directly involved in VAD care
and management, education, and/or the evaluation of organizational performance of VAD care
and management.
3
PURPOSE STATEMENT
This INS white paper was prepared to provide guidance and a framework for developing
organizational policies and procedures, and tools for VAD care and management and data
collection. Though bundled interventions have been shown to improve infection rates, this white
paper does not outline specific VAD management bundle interventions since many postinsertion
bundles have been successfully implemented, each identifying varying components.3,10-15 Rather,
the intent is to provide tools that guide clinicians to safe, effective, evidence-based VAD
LITERATURE REVIEW
Key terms included: bundle interventions, central line-associated bloodstream infection, vascular
access device failure, and complications associated with vascular access and intravenous (IV)
infusion devices. Data filters were applied to include only peer-reviewed articles written in
English between 2006 and 2019. Clinical guidelines, research studies, and expert reports were
Evidence-based guidelines or standards for VAD care and management have been
developed through numerous organizations. The task force reviewed the following sources:
(INS)16
Society (ONS)18
4
• A.S.P.E.N. Parenteral Nutrition Safety Consensus Recommendations, American
Care Hospitals: 2014 Updates. Association for Professionals in Infection Control and
HAND HYGIENE
Although there are many examples of gaps between evidence and practice that lead to
complications with VADs, hand hygiene represents a consistent and on-going gap. Despite the
importance of hand hygiene in preventing morbidity and mortality in health care, research shows
that health care workers do not practice appropriate hand hygiene. One study cited figures of
only 40% adherence.21 Poor compliance numbers have remained relatively steady over the years,
despite many research studies and interventions. Compliance with hand hygiene is improved
when standard mechanisms for auditing compliance are established and dissemination of the
results occurs in multiple forums to raise awareness and promote accountability.22 Incorporating
process and outcome structure in policy for hand hygiene as it relates to vascular access is
essential given the known preventative impact of hand hygiene in interrupting the potential for
pathogen transmission.
therapeutic treatments. Although often necessary for therapeutic intervention, VADs are also
frequently associated with complications that represent patient harm and financial burden.
Complications leading to negative outcomes may include failed vascular access insertion
5
attempts, bloodstream infection, infiltration or extravasation, dislodgment, occlusion, mechanical
The literature defines any negative outcome associated with peripheral IV access as an IV
failure. Prevalence of IV failure varies from 12% to 50% for all peripheral catheter types.5,25-27
With the exception of device malfunction, peripheral VAD failure is associated with human
error, clinical judgment, and differing scopes of practice and levels of competency for device
CLABSIs are associated with increased mortality and morbidity and are known to
increase the cost of providing care in intensive care units.28 Several studies have shown that
competent decision-making by clinicians inserting and caring for VADs decreases device failure
and complications.7,11,29
data which makes it difficult to interpret the results and make practice changes that improve
outcomes related to complications. The study showed that 43% of the respondents thought that
quality metric data for CLABSI, such as infection incidence and rates, were complex and
unreliable. Hence, clinicians benefit from explicit, best practice information that is readily
available for clinical use. A focus on providing structured processes can produce higher fidelity
Risks associated with access of VADs include the potential for intraluminal and
extraluminal contamination, loss of patency, catheter failure, and/or erroneous laboratory values
associated with adsorption of infused medications.5,32,33 In theory, the more times a catheter is
6
accessed, the higher the risk for introduction of pathogens that can result in lumen colonization
Minimizing the number of entries into the vascular access system is an important risk-
reduction strategy.18 System entrance is defined as any manipulation of the system to infuse
medications or solutions, withdraw blood, and/or change administration sets and add-on devices
including needleless connectors. In order to take advantage of this risk reduction strategy, entry
into the VAD at any point on the infusion system should be performed when it will add value to
the plan of care and not merely for convenience. Critical thinking related to entering or
manipulating the entire infusion system can be developed through education and practice.34
Catheter patency is described as the ability to flush the device without resistance and
presence of a blood return.35 Occlusion can be defined as (1) lack of free-flowing blood return,
(2) inability to infuse fluids, (3) increased resistance when flushing, or (4) sluggish flow.
Occluded catheters delay therapy and may act as a nidus for infection when the occlusion is
thrombotic. Since catheter patency is essential for safe and timely infusion therapy, guidelines
for assessing VAD patency and treating occlusions to reestablish patency must be included in
Though obtaining laboratory samples from CVADs is a common practice, it can lead to
catheter occlusion and fibrin deposits in the lumen which can also be a nidus for infection.
CVADs requiring alteplase to treat catheter occlusions have been shown to be positively
inserted directly through the layers of skin, microbes attach to the catheter surface. In addition,
white blood cells, platelets, and plasma proteins also attach to the catheter surface. Fibrin strands
7
form as an early physiologic response to the catheter and often attach to the adjacent vein wall as
well as the catheter. The fibrin strands can become a sheath that acts as a host site for newly
arriving bacteria as well as continued clot formation.38 However, it remains essential to assess for
blood return even considering this discussion of potential risks related to blood sampling from
CVADs. It is important to remember that the length of time the blood remains in the catheter and
proper flushing will affect the amount of plasma proteins that attach to the catheter lumen.
The Standards recommends carefully analyzing risks versus benefits before using VADs
for obtaining blood samples.16 Risk-benefit assessment is needed for each entry into the infusion
system, including access for blood sampling, to ensure that the benefit outweighs the risks. If
after careful assessment, the patient has limited peripheral vasculature, or a history of vasovagal
reaction to needle punctures, obtaining blood specimens through a CVAD may be worth the
additional risk. However, drawing blood samples from a CVAD “to save the patient a
venipuncture” or for mere convenience, may increase the risk of CR-BSI. In such cases,
peripheral venipuncture may be the less risky option.18 It is important to educate patients and
families about the associated risks involved in blood sampling. Clinicians should also be
comfortable initiating a discussion with both the provider and the patient to examine how the
laboratory results will direct patient care, and to weigh the risk-benefit ratio of obtaining the
samples from VADs. Careful consideration of vessel preservation must be incorporated in the
risk assessment.
All catheters attain some level of biofilm within 24 hours of insertion.39 Biofilms are
to each other and to catheter surfaces. Improper VAD insertion and care and management
8
practices can affect how many organisms are available for biofilm formation on intraluminal and
extraluminal catheter surfaces.40 Even with appropriate skin antisepsis prior to catheter insertion,
microbes in the deep layers of the skin around the hair follicles and sweat glands can attach to
the extraluminal surface of catheters on insertion. Inadequate stabilization and securement of the
VAD can lead to back and forth catheter movement in the vessel and biofilm dissemination from
unnecessary catheters can mitigate infection risk. Intraluminal biofilms are associated with
introduction of microbes into the lumen of the catheter with each entry into the system and with
needleless connector and administration set changes. Once formed, these intraluminal biofilms
can be disseminated into the bloodstream during infusions or when flushing, depending on the
infusion system. Failure to disinfect connectors or improper use of connectors can affect catheter
patency and increase risk of intraluminal contamination. There is a general lack of knowledge
use.38,43
Disinfection Caps. A systematic review of the literature conducted in 2019 indicated that
the combined use of alcohol disinfection caps and alcohol wipes were associated with less CR-
BSIs than alcohol wipes alone.44 There continues to be confusion around the need for
disinfection of needleless connectors before accessing VADs even in the presence of passive
disinfection caps.
9
Administration Sets. Administration sets are an integral component of the infusion
system. Proper care and management of VADs includes changing administration sets, add-on
devices, and needleless connectors at established intervals.16 Use of standard antiseptic nontouch
technique (ANTT®) provides guidance for connecting and disconnecting all components of the
5 to 7 days when transparent dressings are used, at least every 48 hours for gauze dressings, and
immediately when the dressing becomes loose or soiled.16,46,47 Management of dressing integrity
and adherence has been shown to decrease the risk of CLABSI. In 1 study, multiple dressing
disruptions were associated with increased skin colonization upon catheter removal and the risk
important, a randomized, controlled trial comparing the superiority of differing types of dressing
interventions for peripheral VADs demonstrated similar failure rates among all groups.49
organizational resources available to safely perform VAD care and management. Organizations
must develop policies and procedures that address each type of VAD (peripheral or central),
vascular route (venous, arterial, intraosseous), and category (permanent, temporary, tunneled,
nontunneled), and outline steps for care and management. Organizational policies, procedures,
and practice guidelines must be based on current research findings and best evidence.16 Widely
published procedural resources may be used to develop policies and procedures but should not be
10
Organizations supporting clinicians who perform VAD care and management must create
processes for collecting, analyzing, and reporting quality outcome data including: VAD dwell
thrombosis, and CR-BSI.16 Clinicians must collaborate with the infection prevention team to
analyze and disseminate quality outcome data to facilitate evidence-based best practices within
the organization. Based on the findings of this literature review, the following elements are
INFECTION PREVENTION
• Performance of hand hygiene immediately before accessing or caring for any VAD is imperative.
• Disinfect needleless connectors with every entry into the system and assess need for replacement.
Limit unnecessary entries into the infusion system.
• Alcoholic chlorhexidine is used for skin antisepsis prior to dressing placement when available.
VAD NECESSITY
• The interprofessional care team must meet daily to discuss VAD necessity, appropriateness,
complications, and future plans for vascular access.
• VADs must be removed immediately with an unresolved complication, discontinuation of infusion
therapy, or when no longer necessary for the plan of care.
11
RECOMMENDATIONS
INS asserts that a comprehensive organizational approach to VAD care and management
is imperative to ensure safe and efficacious patient care. An evaluation of current organizational
structures can help determine areas that need improvement (Table 1).
Policies and Procedures. Review organizational VAD policies and procedures; check to
ensure current reputable national standards and guidelines have been utilized to substantiate best
practice. Note the specific VADs and supplies described and compare with organizational
purchasing and supply lists to detect omissions or inclusion of products no longer used.
Determine if unique directions for use or special considerations for products/supplies used in the
organization merit inclusion in policy and procedure documents (Table 2). Establish a process to
Quality Outcome Data. Review organizational VAD care and management quality
outcome data to ensure all measurable components are captured including, but not limited to
hand hygiene, CLABSI, CR-BSI, occlusion, thrombosis, phlebitis, extravasation, and infiltration.
These data inform leaders and clinicians where VAD care and management improvement is
tool for capturing VAD quality outcome data. Review documentation fields to ensure VAD
performance measures can be documented with specificity; see Table 1 for examples. Leaders
and clinicians must engage the health informatics team to build/modify the necessary
documentation fields.
12
Clinician Education and Competency Records. Review documentation of clinician
education and competency status. All clinicians performing VAD care and management must be
educated according to organizational policy and procedures. Structures must be in place to meet
employee orientation needs, annual competency review, as well as just-in-time education that
CONCLUSION
in VAD care and management. It is essential that each organization (1) develops policies and
procedures to align VAD care and management with recognized standards of practice; (2)
integrates unique aspects of organization-selected VAD care products into policies and
procedures and establishes expectations for adherence to these directives; (3) develops a
framework for gathering and analyzing clinical data related to patient outcomes for VAD care
and management; (4) utilizes quality outcome data to facilitate evidence-based best practices
within the organization; and (5) evaluates and facilitates educational programming to validate
clinician competency.
13
TABLE 1. ORGANIZATIONAL EVALUATION FOR VAD CARE AND MAINTENANCE
•VAD policies and •Data must include VAD •The following items must be •Each clinician must have
procedures must be: metrics and complication documented: documentation of
•Applicable to all types of statistics: •Insertion – date, vessel, site, education and competency
VADs managed in the •Hand hygiene VAD type, gauge, French, validation for:
organization •CLABSI, CR-BSI lumens, dressing, clinician •VAD device selection and
•Based on current evidence •Occlusion •VAD assessment – site insertion
outlined in reputable •Thrombosis inspection, dressing •VAD care and management
national standards and condition, securement, •VAD discontinuation
•Phlebitis
guidelines for practice administration set, patency •VAD complication
•Extravasation, infiltration
•Designed to address all •VAD necessity – daily management
selected VAD products used assessment and plan for use •Medication administration
in the organization •VAD discontinuation - •Phlebotomy
according to manufacturers' reason for discontinuation
instructions •Dressing change
•Structures must exist that •Administration set and add-
facilitate adherence and on change
compliance to these •Complications -
organizational directives interventions
•Infusate(s)
14
TABLE 2. VAD SUPPLY ORGANIZATIONAL POLICY AND PROCEDURE
DEVELOPMENT TOOL
15
TABLE 3. ESSENTIAL VAD PRACTICE ELEMENTS AND DATA COLLECTION a
16
Clinical Practice Performance Measure Data Collection
Component
Administration Set Administration set change practice Documentation of administration
Change Administration sets, including add-on set change
devices, are changed at established Date and time
intervals depending on the type of Labels applied
administration and infusate Add-on devices placed including
Change immediately when contamination needleless connectors/alcohol
is suspected or when product integrity is caps
compromised Restart of infusates, rates and
Minimize the number of manipulations programming checked
and entries into the system If contamination is suspected,
Label administration sets date of document event/occurrence
initiation or date of change describing situation and
Label administration sets used for prescriber notification
medications that are administered via
specialized access devices (eg, intraspinal,
intraosseous, subcutaneous)
Patency, Flushing, and Patency, flushing and locking practice Documentation of patency
Locking VADs are flushed and aspirated for a Date and time assessed
blood return prior to each intermittent Rate blood return (eg, brisk,
infusion to assess catheter function and sluggish)
prevent complications Locking solution used and
For continuous infusions, assess patency volume instilled
for any clinical indication that the device Catheter clearance
is no longer functional, or any complaint performed/outcome of
of discomfort intervention
VADs are flushed after each infusion to
clear the infused medication from the
catheter lumen
VAD is locked after completion of the
final flush to decrease the risk of
intraluminal occlusion and CR-BSI
Single-use flushing and locking systems
are used
VAD patency is assessed using a 10-mL
syringe
Blood Sampling via VAD blood sampling practice Documentation of VAD blood
VAD Assess risk vs benefit prior to using VAD sampling
for blood sampling Decision process for blood
Eliminate unnecessary laboratory tests sampling via VAD
Reduce the frequency of obtaining blood
samples
Draw blood samples based on clinical
need rather than a routine schedule
Abbreviations: CDI, clean, dry, intact; CVAD, central vascular access device; CR-BSI, catheter-related bloodstream infection; VAD, vascular
access device.
a
data derived from Gorski et al.16
17
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