4^ Avoid all substitutes recommended as “just as good

as BROMO-CAFFEINE.’’*=©9i
of a c LBar
(fac -simile of label. )

AVOID ALL SUBSTITUTES.

KEASBEY & MATTISON CO.’S

GEABOLATED EFPEEVESGESI BAITS.

gold by ail Druggists throughout the Country.

 THE SECRET OF A CLEAR HEAD*
»“ AVOID ALL SUBSTITUTES.”**

KEASBEY & MATTISON

COMPANY’S

a**0/V7q
— K, & M —
EFFERVESCENT ^
FOR BRAIN WORKERS.
Combining the active principle of Guarana with Hydro-
bromic Acid, this preparation more than equals one grain
of Hydrobromate of Caffeine in each heaping teaspoonful.
This delightful effervescent salt is an almost certain
remedy for the relief of the nervous headaches resulting
from overtaxed mental energy or excitement, acute attacks
of indigestion, the depression following alcoholic excesses,
the supra-sensitiveness of chloral, morphia and opium
habitues, and with ladies the headache and backache of
neurasthenia, hysteria, dysmenorrhcea, and kindred dis-
orders.
A great boon and prompt source of relief In almost all
cases of headache and distress attending mental fatigue
and physical exhaustion, it commends itself especially to
Physicians, Teachers, Clergymen, Lawyers, Merchants
and others, following professions or pursuits requiring
nerve energy or subjecting to mental strain.
—
Dose. A heaping dessertspoonful added to a tumbler
half full of water, and drunk during effervescence. This
may be repeated in half an hour if necessary.
MOMO-OAFFEINE IN TEE HEADACHES OF ALOOHOLDM,
THE UOEFHIA HABIT, Etc., Etc.
For the relief of headache, following alcoholic excesses,
or as a potent remedy for the exhaustion, nervous trem-
bling and depression of spirits of confirmed drunkards or
morphia eaters, Bromo-Caffeine is without a rlvAl, As a
remedy for the chronic use of spirits or morphia, Bromo-
Caffeine has been used with good success, its b'raelng
effect lessening the desire for spirits or opium. The morn-
ing headache following late dinners and the to© free use of
champagne, is removed as if by magic, by one or two full
doses of Bromo-Caffeine, as many of our public officials
and “ diners out ” can testify. Where the administration
of morphia causes wakefulness and delirium the ingestion
of one or two full doses of Bromo-Caffeine almost always
induces refreshing sleep and controls the nervous excitation
induced by the morphia, hence its use m persons endeav-
oring to break away from the morphia habit, and from
the excessive drinking of alcoholic beverages.

BROMO-CAFFEINE IN MENTAL EXCITEMENT.

In supra-sensitiveness of the mental faculties as shown
in the constant wakefulness experienced by Brokers, after
an exciting day on ’Change, the insomnia of nervous pros-
tration, and particularly in the nervous excitability and
restlessness of insane patients, this remedy Bromo-Caf-
—
feine is of the greatest service in procuring mental rest
and sleep, as its large use in our Insane Asylums through-
out the United States abundantly testifies.

BROMO-CAFFEINE IN MENTAL EXHAUSTION.

In the confusion of thought suffered by Teachers, Clergy-
men, Scholars, Lawyers and others subjected to undue
mental strain, Accountants who have much statistical work
or large range of calculations, Bank Clerks, and others in
positions requiring rapid and accurate work, and more
especially young girls in schools, near the age of puberty,
the use of Bromo-Caffeine gives a certain tone and clear-
ness to the overworked intellect, only otherwise possible
by abundant rest, fresh air and out-door exercise.

Bromo-Caffeine is sold by all well-known druggists

throughout the civiliaed world, and may ho ohuuaodaloo
of the MMhdann.
 BROMO-OAFFEINE IN PHYSICAL EXHAUBTIOI.
Every physician who has much to do with protract*
ed labor cases will realize the feeling of utter weariness
that follows the anxiety and continuous loss of sleep at-
tending a succession of accouchments. This weariness is
promptly relieved by a dessertspoonful or two of Bromo-
Caffeine and procures the feeling of rest and refreshment
so dear to the sufferer. Physicians in all sections write us
of the great relief they obtain after a weary night’s work
by a full dose or two of Bromo- Cafferne. Samples will be
forwarded to any physician desiring to try it in his own
case.
Many ladies in our large cities who go out “ shopping ”
return home with the almost invariable accompaniment of
**
a sick headache.” This can be obviated by taking one
or two full doses of Bromo- Caffeine before leaving home
or upon returning. In all cases of physical fatigue from
railroad travel, loss of sleep, irregularity of meals, etc.,
etc., the greatest possible relief will be found from a few
doses of Bromo- Caffeine.

BROMO-OAFFEINE in the BACKACHE of DYSMENOR-

RHEA AND NERVOUS EXHAUSTION.
The intense backache which so frequently accompanie*
difficult or painful menstruation, and which is looked upon
so much as a customary matter with many women, that
the physician is frequently never consulted in regard to it,
Is usually greatly relieved or wholly removed by a few
doses of Bromo- Caffeine taken at intervals throughout the
menstrual period. Nature certainly intended that this
mrely physiological process should be practically pain-
Iess, and pains should be taken to relieve the distress
which Fothergill so aptly describes as “ headache in the
back.” Shop girls and others who are obliged to stand
while at work are generally believed to suffer most at
these periods, and while the feeling of languor and lassi-
tude may, as is natural, remain, there is no necessity for
any attendant pain, sick headache or other manifestation*
of “ nerve-tire ” if Bromo-Caffeine is administered.

BROMO-OAFFEINE IN DYSPEPTIC HEADACHES.

A* a result of impaired digestion, headache is one of the
most common symptoms, and it frequently is entirely re-
lieved by a dessertspoonful of Bromo-Caffeine. Of course
its use here is only palliative, as other means must be re-
aarted to to effect a permanent cure.
 1E0M0-0AFFEINE IN HEAT EXHAUSTION, 8UW-
STBOXE, Etc., Etc.

During the past few summers the use of Bromo- Caffeine

by persons exposed to the sun’s rays has been of the
greatest benefit in relieving congestion and headache from
which many, particularly in the larger cities, suffer upon
exposure to the direct rays of the sun. The “ hot waves ”
from June to September in the Middle States, are always
productive (especially if the air is moist and the nights
correspondingly oppressive) of unrefreshing sleep, great
enervation and lessening of vital force, with, usually,
headache. We desire most strenuously to impress upon
our medical friends that above all remedies for the head-
aches accompanying “ heat exhaustion ” or attending un-
due exposure to the sun’s rays, stands Bromo- Caffei?ie.
In India, Ceylon and other hot countries the use of Bromo-
Caffeine for this purpose among Europeans is very large,
and it is the remedy now most depended upon. Last
summer in one very marked case of mental derangement
following sunstroke, brought to our notice, its use calmed
the patient, and induced sleep, after all the usual reme-
dies had utterly failed ! Aside from its calming influence
on the cerebral nerve centres, its property of inducing free
perspiration is useful to most patients during the heated
term. In the headaches induced by undue exposure to
the sun, or by the fatigue of traveling, there is nothing
that families who are for a time in the hot months absent
from your professional care, can use with greater safety
or certainty of prompt relief. If you have not already
done so, may we hope that you will recommend it to your
patients “ to take away with them.*’

BBOMO-CAFFEINE IN SEA-SICKNESS, THE NAUSEA OP

PBEGNANOT, BAILBOAD TBAVELING, Etc.
As the best of all remedies for “ Mai de Mer" Bromo-
Caffeine holds deservedly a high place upon almost every
steamship line leaving our ports, and its use alone or alter-
nating with champagne or other carbonated beverage (the
headache resulting ordinarily from the use of which is
prevented by the Bromo- Caffeine) obviates, in a great
majority of cases, the necessity of keeping to the cabin or
berth. In railroad traveling, where there is much swing-
ing of the cars, a dose or two promptly relieves the feeling
of mmmu m iAm cspcricaeed.
 GRAN. EFF. VICHY SALT
( GRAND GRILLE. )

As a type of the alkaline mineral waters, the daily use

of Vichy has frequently proved extremely valuable in
hepatic derangements, as well as in rheumatic affections
and other diseases depending upon acid secretions. Dur-
ing the warm weather of our Northern climates the regular
daily use of it acts as a corrective, regulating errors of
diet and preventing fermentation and sour stomach. The
disagreeable acid eructations in some forms of dyspepsia
are frequently controlled by the regular morning glass of
Vichy, repeated if necessary. When a teaspoonful of
Keasbey &
Mattison Co.’s Gran. Eff. Vichy Salt is placed
in a tumbler half full of moderately cold water, it forms a
grateful and refreshing draught identical with the natural
water, and for all remedial uses the Gran. Eff. Vichy Salt
may profitably replace the expensive and often “stale”
water from the Vichy Spring. The Grand Grille is es-
teemed by competent medical authority as the most gen-
erally beneficial of the many springs at Vichy, and it is
the water of this spring which is accurately reproduced
by Keasbey &
Mattison Co.’s Granulated Effervescent
Vichy Salt.

GRAN. EFF. CITRATE MAGNESIA.

The convenience of this preparation to travelers, or the
family, compared with the popular solution, renders it too
well known to be dwelt upon. We recommend it as a
pleasant and efficient laxative and refrigerant. The ease
with which it is taken by children frequently renders it
particularly desirable.
To travelers our Granular Citrate of Magnesia is indis-
pensable It occupies relative to its medicinal activity
but one-eighth of the space occupied by the well-known
solution, and if kept well corked will retain its efficiency
in any climate for any length of time.
One or two teaspoonfuls added to half a tumbler of
water, fo r ms a grateful and refreshing draught, with con-
tinued sparkling effervescence, delightfully cooling in it®
effect.

ALWAYS GET THAT MADE BY KEASBEY & MAf T<SON CO.

 (ULAN. EPF. KISSINGEN SALT.
( RAKOCZY. )

Belonging to the class of purgative mineral waters, the

action of Kissingen is that of a mild laxative rather than a
cathartic. Its use is principally that of a summer aperient,
since its action is upon the secretory organs, its use pro-
moting a natural and healthy action of the skin and kid-
neys. The Keasbey & Mattison Co.’s Gran. Effervescent
Kissingen Salt, when added in the quantity of a tea-
spoonful to a glass two-thirds full of moderately cold
water, reproduces in all its sparkling brilliancy the natural
water of the famous Rakoczy Spring.

GRAN. EFF. CEAB ORCHARD SALT.

( CRAB ORCHARD, KV. )
This salt represents the purified product of the Crab
Orchard Springs, freed from clay, alumina, and other
nauseous and inert constituents. The ordinary salt has
had a large use for many years and has proved of excep-
tional value as a cathartic in cases of hemorrhoids (piles).
Persons of a sedentary disposition or occupation use the
Keasbey & Mattison Co.’s Gran. Eff. Crab Orchard Salt
with surprising benefit, while among the railroad employes
of the South and Southwest (many of whom suffer from
hemorrhoids) its use is large and constantly increasing.
It is the most active of the American saline waters, equal-
ing Friedrichshalle or Pullna in its cathartic effect. The
dose is one or two tablespoonfuls in a large glass of mod-
erately cold water, and it should be taken if convenient
about half an hour before breakfast. The more water
taken with this salt, the more beneficial the action.

GRAN. EFF. ALKALITHIA.

A common sense remedy for the treatment, alleviation
of symptoms and permanent cure of Rheumatism, Cystitis
and other diseased conditions resulting from excess of acid
in the secretions. “Alkalithia ” is a distinctive and easily
remembered name given this granulated effervescent pre-
paration for the sake of brevity and to insure the use of the
genuine preparation. It tones up the heart muscle neu- ;

tralizes the excess of acid in the system acts as a powerful

;

diuretic and avoids the danger of heart trouble now so

common a sequelae of the free exhibition of Salicylic Acid
and the Salicylates.
—
% Dose. A heaping teaspoonful three or four times a day,
preferably to be taken in a large glass of lukewarm water,
the treatment to be continued for some time after the urine
becomes normal, as shown by the blue litmus-paper test.
 ”

PHYSICIANS WILL FIND

KEASBEY & MATTISON
COMPANY’S
BROMO-CAFFEINE
OF THE GREATEST SERVICE IN

Nervous Headaches
OF ALL TYPES.

Headaches from Loss of Sleep, Physical Fatigue, Ex-

cessive Study, Mental Anxiety, Neurasthenia, Dysmenor-
rhoea, Pregnancy or other Ovarian Irritation. Relieves
Insomnia, and is very useful in Asthma, Whooping Cough
and Nervous Cough. Prevents Tinnitus Aurium during
the Administration of Quinine. Cures Seasickness.
Quiets the Restlessness of Alcoholism, Morphia Craving,
&c. Relieves Anxiety and Promotes Sleep.
AVOID and DISCOURAGE IMITATIONS and SUBSTITUTIONS.
The Caffeine preparations were originated by Messrs. Kbasbey &
Mattison, twenty years ago, and are in use throughout the world.
There are plenty of imitations of Keasbey & Mattison Company’s
Granulated Effervescent Citrate of Caffeine, and Granulated Effervescent
Bromo-Caffeine, made by envious or irresponsible competitors. There
are plenty of substitutes being recommended every day, and sold as

“Just as Good, Sir, as Keasbey & Mattison’s I

by the money-making, unscrupulous venders of such preparations.

Physicians who desire to have their patients get the article properly
made, and of guaranteed strength and quality, will not fail to instruct
Keasbey & Mattison
their patients to get, or their druggists to dispense,
Company’s Effervescent Citrate of Caffeine, or Effervescent Bromo-
Caffeine, and afterwards see that their instructions are followed.

KEASBEY & MATTISON COMPANY,

Originators and Manufacturers of the Genuine Granu-
lated Effervescent Caffeine Preparations.

AMBLER, PENNA.