BCS Classification Of Some Drugs:

S/No Medicine Strength Solubility Permeability Class

1 Abacavir 200mg High Low 3
2 Acetazolamide 250mg Low Low 4
3 Acetylesalic acid 500mg High High 1
4 Acetylesalic acid 100mg High High 1
5 Aciclovir 200mg High Low 3
6 Albendazole 400mg Low Low 4
7 Allupurinol 100mg High High 1
8 Amiloride HCL 5mg High High 1
9 Amitriptyline HCL 25mg High High 1
10 Amlodipine 5mg High High 1
Borderline BA
11 Amodiaquine 200mg High (3/1)
>75%
Amoxicillin+ Cluvanic 500mg+
12 High+High High+ Borderline (1/3)
Acid 125mg

13 Amoxicllin Anhydrous 500mg High High 1

Artemether+ 20mg+
14 Unknown Low (4/3)
Lumefentrine 120mg
15 Ascorbic Acid 50mg High High 1
16 Atenolol 100mg High Low 3
17 Azithromycin 500mg Low Low 4
18 Benzidazole 100mg High Low 3
19 Carbamazepine 200mg Low High 2
20 Cefixime 400mg Low Low 4
21 Chloramphenicol 250mg High Low 3
Chloroquine PO4 or
22 150mg High High 1
SO4
Chlorphenamine BA 25-59% First
23 4mg High (3/1)
Hydrogen Maleate pass

24 Chlorpromazine HCL 100mg High Low 3

BA 70-82% first
25 Ciprofloxacin HCL 250mg High (3/1)
pass
26 Diazepam 5mg High High 1
27 Digoxin 250mcg High High 1
28 Doxycyline HCL 100mg High High 1
29 Enalapril 2.5mg High Low 3
30 Ethambutol HCL 400mg High Low 3
31 Fluconazole 50mg High High 1
32 Folic Acid 5mg High Low 3
33 Furosemide 40mg Low Low 4
34 Glibenclamide 5mg Low Low 4
Sublingual
application
permeabilty in oral
35 Glyceryl trinitrate 500mcg High (3/1)
cavity more imp
than Gi
Permeabilty
36 Griseofulvin 250mg Low High 2
Borderline
37 Haloperidol 2mg Low (4/3)
<0.01mg/ml
38 Hydralazine HCL 50mg High Low 3
39 Hydrochlorthizide 25mg High Low 3
40 Ibuprofen 400mg Low High 2
41 Iopanic Acid 500mg Low High 2
Sublingual
42 Isoniazid 300mg High Borderline
application (3/1)
permeabilty in oral
43 Isosorbide dinitrite 5mg High (3/1)
cavity more imp
Practically insoluble than Gi
44 Ivermectin 6mg Low
Permeabilty (4/2)
in water
45 Lamivudine 150mg High High 1
46 Levonoergosterel 30mcg High High 1
Levothroxine sodium
47 100mcg High Low 3
salt
48 Lithium Carbonate 300mg High High 1
49 Mebendazole 500mg Low Low 4
50 Metformin HCL 500mg High Low 3
51 Mefloquine HCL 250mg Low Low 4
52 DL-Methionine 250mg High High 1
53 Methyldopa 250mg High Low 3
54 Metaclopramide HCL 10mg High Low 3
55 Metronidazole 500mg High High 1
56 Morphine Sulfate 10mg High B.A~ 30% (3/1)
57 Melfinavir Mesilate 250mg Low Low 4
58 Neostigmine Bromide 15mg High Low 3
59 Nevirapine 200mg Low High 2
60 Nefidipine 10mg Low High 2
61 Nifurtimox 250mg High Low 3
62 Nitrofurantoin 100mg Low High 2
63 Paracetamol 500mg High High 1
64 Phenobarbital 100mg High High 1
65 Phenytoin sodium salt 100mg Low High 2
66 Potassium Iodide 60mg High High 1
67 Praziquantel 600mg Low High 2
68 Prednisolone 25mg High High 1
Primaquine
69 15mg High High 1
diphosphate
70 Proguanil HCL 100mg High High 1
71 Promethazine HCL 25mg High High 1
72 Propranolol HCL 40mg High High 1
73 Propylthiouracil 50mg High High 1
74 Pyrazinamide 400mg High High 1
75 Pyrodoxine HCL 25mg High High 1
76 Ranitidine HCL 150mg High Low 3
77 Riboflavin 5mg High High 1
78 Rifampicin 300mg Low High 2
79 Sulbutamol sulfate 4mg High High 1
80 Spironolactone 25mg Borderline Low (4/3)
81 Stavudine 40mg High High 1
Sulfamethoxazole+ 400mg+
82 Low+Low High+High (2/2)
Trimethoprim 80mg
83 Salfasalazine 500mg Low Low 4
84 Thiamine HCL 50mg High Low 3
85 Trimethoprim 200mg Low High 2
86 Valporic Acid 500mg High High 1
87 Verapamil HCL 80mg Low High 2
88 Warfarin 5mg High High 1
89 Zidovudine 300mg High High 1
90 Zinc Sulfate 10mg High Low 3
91 Cyclosprine 25mg Low Low 4
92 Clindamycin 150mg High High 1
93 Cyclophosphamide 25mg High High 1
94 Etoposide 100mg Low Low 4
Borderline BA 76-
95 Flucytosine 250mg High (3/1)
8%
96 Levofloxacin 500mg High High 1
97 Mercaptopurine 50mg Low Low 4
98 Methotrexate 2.5mg High Low 3
99 Ofloxacin 400mg High High 1
100 P-Aminosalisylic acid 500mg Low Borderline 80% (4/2)
101 Sulfadiazine 500mg Borderline Low (4/3)

Reference: https://www.who.int/medicines/areas/quality_safety/quality_assurance/Propos
Reference: https://www.who.int/medicines/areas/quality_safety/quality_assurance/Propos
/quality_assurance/ProposalWaiveVivoBioequivalenceRequirementsModelListEssentialMedicinesImmediateReleaseSolidOralD