15. 03. 2020. Bioperine (Containing Piperine) Safety Information | ConsumerLab.

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Bioperine Safety
Question:
Is it safe to take Bioperine (which contains piperine from black pepper)?

Answer:
Piperine (from black pepper) can enhance the absorption or bioavailability of certain compounds, such as
curcumin from turmeric. Bioperine is a branded extract of black pepper which is 95% piperine and is
commonly included in curcumin supplements, but is also sold separately. Be aware that piperine can
interact with many medications and may also have anti-platelet effects. In addition, it may cause
gastrointestinal side-effects and, potentially, bleeding, at somewhat higher-than-suggested doses. See
the "Concerns and Cautions" for black pepper extract within the Turmeric/Curcumin Supplements
Review.

Learn More About Black Pepper Extract

What supplements should I stop taking before surgery? >>

I read that turmeric may be a GI irritant. I have GI problems and wonder if I should avoid turmeric
and curcumin? >>

I recently read that turmeric is only effective if it is combined with black pepper. Is this true? >>

Can turmeric or curcumin with black pepper extract cause constipation? I had this problem when
taking a curcumin formula with piperine, but it resolved when I switched to a curcumin
supplement without this added ingredient. >>

Is it safe to take curcumin or turmeric supplements for a long period of time? >>

See other recent and popular questions >>

COMMENTS Add Comment

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15. 03. 2020. Bioperine (Containing Piperine) Safety Information | ConsumerLab.com

Carrie17237 October 14, 2018

I personally had a bad experience with Bioperine added to Tumeric. I am Bi-Polar type II and take
several medications. After taking the new kind of Tumeric with pepper additive I just did not feel "right".
Something was off for 2 months with my moods changing. It was only in hindsight that I considered the
new Tumeric as the problem. I stopped taking it and within a week I felt better. Since then I make sure I
do not take any supplement containing a pepper adjuvant. The FDA should stop its usage...99% of the
population will not know how it can mess with other medications.
Comment on Post

Carolyn18196 August 13, 2019

Better idea: Have the FDA simply tell Bioperine users where to find the information explaining
how piperine works in the liver. Once that knowledge is widely available then people can make
their own decision to use or not based on their own situation. That will allow us 1%er's to
continue to getting the maximum benefit from curcumin.
Comment on Post

This CL Answer initially posted on 8/30/2017. Last updated 10/14/2018.

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