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Prevents nucleic acid ●Prophylaxis and ●Contraindicated CNS: headache, ● Monitor vital signs; watch for
Generic Name: uncoating during viral cell treatment of with allergy to Trouble dizziness, fatigue, hypotension.
replication, preventing illness caused by amantadine, sleeping, naus depression,
penetration in host. Also inflfluenza A virus rimantadine;lacta ea, vomiting, l insomnia, poor ●Closely monitor nutritional
causes dopamine release in adults tion. oss of concentration, status and hydration.
Rimantadine
hydrochloride from neurons. appetite, dry asthenia,
●Prophylaxis ●Use cautiously mouth, weakn
nervousness
against with seizures, ess, dizziness,
inflfluenza A virus liver or renal drowsiness, or CV: hypotension ● Advise patient to take several
Brand Name: in children disease, nervousness hours before bedtime.
may occur. EENT: tinnitus
pregnancy.
●Unlabeled uses: ● If patient’s taking syrup, tell
GI: nausea,
Treatment and him to use specially marked oral
Flumadine vomiting, diarrhea,
prophylaxis of syringe or measuring device to
abdominal pain,
H1N1 (swine flflu) ensure accurate dose.
dyspepsia, dry
infection,
mouth, anorexia ● Instruct patient to contact
Classification: treatment of
prescriber if symptoms don’t
inflfluenza A in Respiratory:
improve within 2 to 3 days.
children dyspnea
● Caution patient to avoid
Pharmacologic- Skin: rash
classification: driving and other hazardous
activities until he knows how
Miscellaneous drug affects concentration,
and
motor function, and alertness.
anticholinergic-like
agent
Therapeutic
Classification:
Antiviral
inhibit DNA and RNA -To treat acute -Contraindicated Common CNS: drowsiness, -Watch for acute life-threatening
Generic Name: synthesis by forming lymphocytic with allergy to dizziness, asthenia, arrhythmias, which may occur
complex with DNA. Also leukemia, acute doxorubicin -Pain along the during or within a few hours after
fatigue, malaise,
exerts immuno-suppressive nonlymphocytic hydrochloride, site where the administration.
paresthesia,
Doxorubicin activity. Cell-cycle–S-phase leukemia; bladder,malignant medication was
headache,
breast, gastric, melanoma, kidney given.
specific. depression,
Hydrochloride epithelial ovarian,
carcinoma, large -Monitor for cardiomyopathy and
insomnia, anxiety,
or thyroid cancer;bowel carcinoma, -Nausea or subsequent heart failure with
emotional lability
brain tumors, CNS vomiting (You chronic overdose (more common
Hodgkin’s will be
Brand Name:
metastases, in children).
disease;
myelosuppression, pretreated for
neuroblastoma this side CV: chest pain,
cardiac disease
hypotension,
or Wilms’ tumor; (may predispose to effect)Later ● Stay alert for erythematous
Adriamycin PFS, Side Effects: tachycardia,
non-Hodgkin’s cardiac toxicity), streaking along vein next to
Adriamycin RDF, (within two peripheral edema,
Rubex
lymphoma; small- pregnancy, injection site, which may indicate
weeks after cardiomyopathy,
cell lung lactation. too-rapid infusion.
treatment heart failure,
carcinoma; and
begins) arrhythmias,
soft-tissue
pericardial
sarcoma or ●Use cautiously ● Watch for nausea and
-Low blood effusion
osteosarcoma. with impaired vomiting. Administer antiemetics
Classification: counts . Your
hepatic function, as needed.
previous courses of white and red
doxorubicin or blood cells and GI: nausea,
daunorubicin platelets may vomiting, diarrhea,
Pharmacologic -Check for superinfection or
classification: ●To produce therapy (may temporarily constipation,
regression in the predispose to enlarged abdomen, hemorrhage caused by persistent
decrease. This
Anthracycline following abdominal pain, bone marrow depression (but
cardiac toxicity), can put you at
neoplasms: ALL, prior mediastinal increased risk dyspepsia, oral expect WBC counts as low as
AML, Wilms candidiasis, 1,000/mm3 during therapy).
irradiation, for infection,
Therapeutic
tumor, concurrent anemia and/or moniliasis,
Classification:
neuroblastoma, cyclophosphamide bleeding. stomatitis, glossitis,
Antibiotic and soft tissue and esophagitis, -Watch closely for infusion-
Antineoplastic therapy related reactions and
bone sarcoma, (predispose to Uncommon dysphagia.
breast carcinoma, cardiac toxicity). anaphylaxis.
ovarian -Eyes watering
carcinoma, GU: albuminuria,
transitional cell -Mouth sores hyperuricosuria, red ● Monitor CBC, hepatic profile,
coagulation tests, ejection
Reference/s:
http://chemocare.com/chemotherapy/drug-info/doxorubicin.aspx#:~:text=Doxorubicin%20is%20the%20generic%20name,the%20generic%20drug%20name%20Doxorubicin.
McGraw-Hill Nurse's Drug Handbook 7th Edition (pp 398 - pp 401)
Jones and Bartlett Learning 2015 Nurse's Drug Hanbook 4th Edition (pp 1321)
Lippincott's Nursing Drug Guide 2015 (pp 411 - pp 412)