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Seminars in Pediatric Surgery 30 (2021) 151051

Contents lists available at ScienceDirect

Seminars in Pediatric Surgery


journal homepage: www.elsevier.com/locate/sempedsurg

Working as a team in airway surgery: History, present and


perspectives
Michele Torre∗, Roberto D’Agostino, Ivana Fiz, Oliviero Sacco, Pietro Salvati,
Annalisa Gallizia, Francesca Rizzo, Mirta Della Rocca, Serena Arrigo, Antonella Palmieri,
Nicola Stagnaro, Italo Borini, Francesco Santoro, Halkwat Nuri, Giuseppe Pomé,
Maurizio Marasini, Vittorio Guerriero, Luca Pio, Federica Lena, Elisabetta Lampugnani,
Franco Puncuh, Silvia Buratti, Stefano Pezzato, Andrea Wolfler, Annalisa Costa,
Monica Faggiolo, Daniela Tronconi, Maria Annunziata Pinna, Daniela Cordeglio,
Armanda Ferullo, Girolamo Mattioli, Andrea Moscatelli, Annalisa Oneto, Claudia Barbieri,
Marzia Musso
Airway Team of IRCCS Giannina Gaslini, Genova, Italy

a r t i c l e i n f o a b s t r a c t

Keywords: Teamwork is one of the most important trend in modern medicine. Airway team were created in many
Tracheal team places to respond in a multidisciplinary and coordinated way to challenging clinical problems which were
Airway surgery
beyond the possibility of an individual management. In this chapter, we illustrate the historical steps
Aerodigestive team
leading to the development of an airway team in a pediatric referral hospital, describe the present team-
Tracheal surgery
Tracheal stenosis work activity defining the key points for the creation of a team and discussing different organization
models; finally we delineate possible future directions for the airway teams in the globalized world.
© 2021 Elsevier Inc. All rights reserved.

Introduction ical competences are encompassed from multiple specialists coop-


erating on a single patient, integration of different brains and skills
Modern medicine is a teamwork activity. If in the past cen- can exponentially increase the abilities and shorten the learning
tury the role of a single professional was determinant for the fi- curve of a single professional, shared decisions can be easier to be
nal outcome, the present era successes are considered function of taken and defend a single physician, especially in challenging cases
a well organized multidisciplinary activity more than of individ- and at risk of legal considerations. In this manuscript, taking as an
ual abilities. In many fields of medicine and surgery, including air- example the process that led to the creation of an airway team in
way surgery, this cultural and behavioral change became more ev- a pediatric Institution, we will present the historical background of
ident.1 , 2 With the increase of possibilities of successful treatments the hospital before the process, define the key points for the cre-
given by the modern techniques and technologies based in ultra- ation of the airway team, present practical examples of its func-
specialized medicine and surgery, the need of relying on some- tion, discuss advantages and critical points, and finally we will try
one else’s knowledge and skills is nowadays a necessity more than to delineate the future directions.
it was 10 or 20 years ago. Taking as example pediatric airway
surgery, the competences and skills required are so wide that no Historical background
individual surgeon is usually capable of developing them entirely
by himself. In many pediatric Hospital and Institutions, until the end of the
The know-it-all surgeon does not exist anymore. Moreover, the past century, the possibility of management of airway cases was
advantages of a multidisciplinary teamwork are several: more clin- very limited. We describe the local situation of one of the largest
pediatric hospital in Italy, that can be paradigmatic for many other
Institutions in different parts of the world at those times.

Corresponding author at: Pediatric Thoracic and Airway Surgery Unit, IRCCS Gi- At the end of the last century, in our Institution (Giannina
annina Gaslini, Via G. Gaslini 5, 16147, Genoa, Italy. Gaslini Children Hospital, Genoa, Italy) the diagnosis of an airway
E-mail address: micheletorre@gaslini.org (M. Torre). anomaly was usually suspected by the anesthesiologist or inten-

https://doi.org/10.1016/j.sempedsurg.2021.151051
1055-8586/© 2021 Elsevier Inc. All rights reserved.
M. Torre, R. D’Agostino, I. Fiz et al. Seminars in Pediatric Surgery 30 (2021) 151051

sivist based on his/her clinical experience and on patient symp- this specific need is felt. In our Institution, while the need of an
toms. In other occasions, the suspicion of an airway stenosis was airway team was evident since the first 20 0 0s, it was only in 2007
raised by a difficult intubation or tube progression. In either cases, that this decision was taken, in particular thanks to the vision of
to perform a precise endoscopic diagnosis was usually not possi- the Chief of Intensive Care and Surgery Department. The first act
ble. In most cases, the direct laryngoscopy by the anesthesiologist was to send the Gaslini’s pediatric surgeon that was most inter-
was the only diagnostic tool available in the operation room. Flex- ested in airway to Cincinnati Airway Team center, directed by prof.
ible endoscopy was very occasionally performed and usually with Robin Cotton, for a period of 6 weeks. Another similar period of
the patient awake, making the vision below vocal cords almost im- time was spent by the same surgeon in the airway training cen-
possible. CT scan or other radiological studies were used, in some ter located in Santiago of Chile, called Calvo Mackenna Children’s
cases inappropriately, in an attempt to have an idea of the airway Hospital, following the tracheal surgeries of prof. Patricio Varela.
anatomy, but clinical conditions influenced and sometimes heav- The activities of our team started in 20093 . The difficulty in cre-
ily hindered the diagnostic workup. Referred patients were usually ating something new (an airway team) in the specific context of a
not expected, in many cases presented in urgent clinical context, pediatric hospital was mainly due to the factors listed in Table 1. In
and their management was extremely stressful and frustrating. In particular, the lack of specific experience in management of com-
many cases, tracheostomy was the only way to treat these patients, plex airway cases was only the more obvious. The small number
even if the precise diagnosis was unknown. With or without tra- of cases, their complexity, the absence of some expert who can
cheotomy, these patients were usually sent abroad, in the few ex- teach or back the colleagues up in case of complications and the
isting centers where some expertise of such problems was avail- understandable fear of causing the death or seriously harming the
able. The travel to the referral center, often very far from the hos- affected children are important factor preventing the development
pital, was usually very stressful for the accompanying personnel of a new airway team in many Institutions. Some possible theoret-
and hazardous for the patient. ical solutions to each problem can be found in Table 1. The way
Later on, endoscopy became available in many centers, includ- we have been following to organize a new airway team in our In-
ing ours. However, many different professionals were individually stitution was summarized in Table 2.
following their own patients with some airway problems without The goal of our airway team, consistent with the mission of
any cooperation not even dialogue between different experts or ar- our pediatric Institution, one of the largest in our Country, was
eas. Flexible endoscopy was performed by otolaryngologists, anes- to be able to take care of all airway related problems in children.
thesiologists, pulmonologists, but none of them dared to perform To do that, we had to define competencies following the princi-
rigid endoscopy. During this second era of our Institution, the diag- ple that each specialist was the leader of an area, and that the
nosis was more often achieved than it used to be, but the solutions areas of competence should not be overlapping. Apart from obvi-
were almost never available, usually due to the lack of surgical ex- ous assignments (anesthesiologists were in charge for preoperative
pertise. For this reason, many of these patients were still sent away evaluation and intraoperative medical management, cardiovascular
for the treatment. surgeons for procedures requiring cardiopulmonary bypass etc.), in
In our and in many other pediatric hospitals until the year some cases we had to decide “by default” who was expected to
20 0 0, the competences on airway patient management were still do what: diagnostic endoscopic procedures and endoscopic surg-
scattered or overlapping. Moreover, there was no clear leadership. eries were assigned to ENT (for larynx and cervical trachea) or pul-
Otolaryngologists were not always the patient manager because of monologist (low trachea, bronchi). Tracheotomies were assigned to
lacking of experience in endoscopy and/or laryngotracheal surgery. ENT, while all the open procedures were assigned to the airway
The tracheostomies were performed sometimes by them but more trained pediatric surgeons, in cooperation (if necessary) with ENT
often by general pediatric surgeons or other professionals (cardio- or cardiovascular surgeons. In our Institution, all anesthesiologist
vascular surgeon, neurosurgeons). It could happen that laryngoma- and intensivists were trained to perform a flexible endoscopy, that
lacia patients were managed either by otolaryngologists, neona- could be useful during surgery or in the post-operative period. A
tologists, anesthesiologists, pediatricians or pulmonologists in the pediatric surgeon was identified as the team leader, and specialist
same institution, often with different indications for treatment and nurses were assigned to be part of the team, with the task of co-
for surgery, and with different follow up. Apart from tracheostomy, ordination of clinical evaluations, procedures, follow-up, and to be
no one was able to perform laryngotracheal endoscopic or open in contact with the families.
surgery. Starting regular weekly meetings represented a key step for the
Endoscopic evaluation was slowly becoming the preferred tool team. Discussing and sharing cases taught to all members of the
to achieve the diagnosis, giving to radiology a complimentary role team to take responsibility of all difficulties and helped them to
for selected problems. An important clinical and cultural advance- find a shared solution.
ment was achieved with the possibility to record images and To bridge the gap due to lack of experience, each of the profes-
videos and discuss them collectively. Before this, just a single pro- sionals was sent to specialized Centers abroad. The pediatric sur-
fessional could visualize the problem. With the recording, gather- geon who was in charge of the open procedures, which had never
ing to see the images and discuss them as a group became nat- been performed in our Institution before, was sent to GOSH Tra-
ural. Physicians belonging to different specializations were usu- cheal Team for a one-year fellowship. This period not only taught
ally involved in these meetings. All innovations and trends to- us how to manage the airway patients but also inspired us on the
wards easy communication and social interactions between people way to create the team and how this had to function.
helped this process. Airway was the perfect organ to be considered To be assisted during surgeries, we proudly met prof. Philippe
as “social”, being a meeting point for different specialists, such as Monnier from CHUV of Lausanne, one of the most experts in the
otolaryngologists, pulmonologists, pediatric surgeons, thoracic sur- world among airway surgeons, who was a perfect tutor of our
geons, anesthesiologists, intensivists, cardiovascular surgeons, radi- surgeons during the first years of activity. The airway cases were
ologists. This was the germ of the airway teams. scheduled and operated when the mentor was present. Since the
beginning, the principle of the tutoring was that the local team
Creation of a team had to grow and learn gradually to be independent in perform-
ing the procedures under prof. Monnier supervision. He was avail-
The first step for the creation of a Pediatric airway team is usu- able also for pre-operative selection of the cases and for post-
ally a strategical decision, made by hospital administrators, when operative management suggestions. During the first years, despite

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M. Torre, R. D’Agostino, I. Fiz et al. Seminars in Pediatric Surgery 30 (2021) 151051

Table 1
Difficulties and problems commonly encountered before and during airway team setting and possible theoretical solutions.

Difficulty/Problem Possible solution

Overlapping and lacking competences Assignment to different tasks to the specialists


Fragmentation of cases between clinical groups Patient centered model
Often challenging cases, not suitable for learning curve Tutor; sharing difficult cases in groups of experts
Small numbers every year Centralization of cases
Professionals not used to share experiences and discuss Weekly meeting
Different visions and approaches between different professionals Weekly meeting; external advice; tutor
Fear Tutor
Economical burden for the new technology Reduction of costs thanks to organized team

Table 2 last few months, demonstrating typical simple or more compli-


Actions taken in our Institute to create an airway team.
cated clinical situations:
Establishing Goals (what we want to be able to do) Case 1: Patient operated at 2.5 months for ventricular septum
Competence collection (who is doing what now) defect. After 3 weeks at home he presented stridor during a res-
Competence extension (what can be learned by whom and how)
piratory infection. Pulmonologist was called and he performed a
Leadership (who is in charge to the airway team setting)
Internal coordination and adaptation to local environment flexible endoscopy, showing a subglottic stenosis grade 2. He di-
Regular Meeting lated the stenosis with a 6 mm. balloon with an immediate good
Tutoring result. The patient was presented at airway multidisciplinary meet-
Review complications, mortality and morbidity ing and assigned to the otolaryngologists, who performed a second
Improvement actions
dilatation and are now following-up.
Research
Case 2: 4-year old girl with VATER syndrome, operated at birth
for type 3 esophageal atresia . She was referred to pulmonologist
for chronic respiratory symptoms (recurrent infections, cough and
a quite good surgical activity,3 we have been observing a signif- noisy breathing). CT scan showed an anterior compression by in-
icant number of complications, that prompted us to review our nominate artery, reducing tracheal lumen for more than 60%. The
management protocols.4 Regular morbidity and mortality meetings double endoscopy showed: a left vocal cord palsy, a grade 1 to
and a database were the instruments for monitoring our activity 2 subglottic stenosis, a recurrent distal tracheo-esophageal fistula
and identifying areas of weakness with the possible improvement (TEF) and a severe tracheomalacia. The case was presented at the
actions. One example of these was represented by pre-operative airway team meeting and it was decided to perform an endoscopic
antibiotic prophylaxis (or therapy) in airway patients. After adopt- closure of the TEF as first step,which was performed by ENT sur-
ing a much more aggressive pre-operative antibiotic treatment, we geons using trichloroacetic acid.
have been observing a significant improvement of surgical results, After one month a bronchoscopy was performed that showed
as previously reported4 . grade 2 subglottic stenosis, satisfactory closure of TEF and severe
An important factor for the implementation of many institu- middle trachea tracheomalacia with anterior vascular compression.
tional airway teams, including ours, was the attendance to special- Later on, the patient was operated at the same time by pediatric
ized meetings on airway surgery. More and more people from dif- surgeons who performed an open laryngotracheal reconstruction
ferent centers became interested in pediatric airway surgery, and (LTR) with an anterior graft and by the cardiovascular surgeons
focused meetings became more frequent. South America was the who performed an anterior aortopexy through a mini-sternotomy.
area of the world where these meetings were particularly frequent, The patient in actually asymptpmatic in follow-up by pulmonolo-
thanks to the work of different dedicated groups (especially in gists.
Chile, Argentina and Brazil) who were starting to organize them-
selves as Pediatric Airway Teams. These meetings were particularly Discussion
successful because pediatricians and surgeons from multiple spe-
cialties were starting to chat about practical management of air- The cases described demonstrate well how a multidisciplinary
way patients. In these meetings, the sprouting new teams from approach offers the solutions that challenging situations require.
South America and elsewhere could not only share a lot of prac- In this view, it is not important to which unit or department the
tical knowledge and experience in managing difficult clinical situ- patient was initially referred, but what he needs. The same patient
ations, but also find a young and enthusiastic community of peo- will be treated accordingly by the right specialist, or by a com-
ple with different origins and specializations, that was available to bination of professionals, and the case manager will change ac-
support less experienced professionals. It became common, for ex- cordingly. For example, case n. 1, a patient with unknown origin
ample, to organize local surgical workshops where difficult cases stridor, was evaluated by pulmonologists initially, but when diag-
were operated together with more experienced surgeons, or in ev- nosis was established (post-intubation subglottic stenosis) he was
ery time of the year to share difficult cases with the community taken in charge by otolaryngologists. In the other case the man-
and receive answers and advices in a very short time. agement was combined, and during the same anesthesia multiple
Another important step for the development and implementa- procedures were organized. All the team members are involved in
tion of the airway team in our Institution was the possibility to every step of the treatment and kept updated of the outcome.
pick up critically ill patients from other Hospitals (also abroad the Apart from the obvious advantages of managing difficult airway
Country) and transport them to our Institution, including patients patients as a multidisciplinary team, some points remain to be dis-
in ECMO. This facility, made possible by our Intensivist Transport cussed.
Service, enlarged the number of patients referred to us (Fig. 1). The First, is it advantageous to have an airway team? The experi-
same hospital that used to send the airway patients abroad was, ence of aerodigestive teams, in particular in US, demonstrated that
after few years, attracting patients from abroad. they are beneficial in many ways: they reduce unnecessary test-
To show how an airway team can function, we briefly describe ing, they allow a reduction in costs for the healthcare system and
the pathway of some patients, managed in our team during the for the families, they promote the development of new procedures,

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M. Torre, R. D’Agostino, I. Fiz et al. Seminars in Pediatric Surgery 30 (2021) 151051

Fig. 1. The graphic shows of our airway team since its creation. Only the major open tracheal reconstructive surgeries were considered.
Legend:
LTR: Laringo-Tracheal Reconstruction
PCTR/TR: Partial Crico-Tracheal Resection/ Tracheal Resection
Slide T-P: Slide Tracheoplasty
PT: Posterior Tracheopexy

and they are supportive for professionals involved5-8 . In practical pital but are positions not regularly present or even not existent in
terms, this represents an advantage for both patients families and many other contexts.
Institutions. The reduction of the costs thanks to a better organi- Another model of airway team far from US is GOSH airway
zation is a particularly important factor pushing towards the im- team.10 , 11 This is a model probably more surgically focused than
plementation of airway teams and it could help to overcome the the US aerodigestive teams, in particular on tracheal surgery. In
increased expenses due to the new requirements of the team (in- their paradigm, surgical members (cardiothoracic, general pediatric
struments, technology, etc.) surgeon, otolaryngologist) have a main role, and the role of other
Having a team can also increase the number of referrals. We professions (pulmonology, gastroenterology, speech-language and
have observed this trend in our Institution, as shown in Fig. 1 (also respiratory therapy) is focused to prepare or follow the surgery.
considering general reduction of surgical procedures in all the Hos- Interestingly, they adapted some role to specific needs (the inter-
pital due to pandemia and operative theatres limitations in 2020). ventional radiologist was trained in airway endoscopy so he could
How the team should be composed and which patients should perform bronchography and bronchoscopy at the same time). After
manage is another matter of discussion. A consensus paper on the setting of GOSH team, they reported increase in referral, im-
functions and composition of an aerodigestive team has been pub- proved outcomes, and a dramatic reduction in the cost of care.10
lished in 2018, based on the opinion of a multidisciplinary and From these experiences, we can state that there is not a “one-
multicenter expert panel, using the Delphi method.9 The panel was size-fits-all” model of airway team, and that it is probably neces-
composed of 33 specialists from 11 aerodigestive centers in the sary to adapt the organization to everyone specific need and con-
United States (12 pediatric pulmonologists, 11 pediatric otolaryn- text.
gologists, 8 pediatric gastroenterologists, and 2 speech language Some basical requirements are, however, necessary in an Insti-
pathologists). According to the experts, aerodigestive teams are fo- tution where an airway team will be created. For example, the pos-
cused on patients with a broad range of different symptoms, some sibility of performing triple endoscopy (flexible and rigid airway
more related to feeding difficulties and congenital or chronic con- and esophago-stomach-duodenum endoscopy), the availability of
ditions (as patients with failure to thrive, or with lung, genetic, the equipment for operative endoscopy, the presence of a neonatal
neurodevelopmental or craniofacial anomalies), others more “sur- and pediatric intensive care unit and of a cardiovascular unit, with
gical”, as patients with esophageal atresia, laryngotracheal steno- the possibility to perform a procedure on cardiopulmonary bypass
sis, cleft). Interestingly, the medical specialties considered as “core or ECMO. In absence of one of these facilities, it is probably bet-
members”, with input required for all patients, were: gastroen- ter to refer the patient elsewhere before doing everything. Even a
terology, pulmonology, otolaryngology, speech-language pathology, “simple” endoscopic evaluation under anesthesia could be trans-
to which two other non medical professions -coordination and formed in a disaster in an inappropriate environment. In our ex-
nursing- were added. This probably reflects the composition of perience, for example, an infant with a severe congenital tracheal
the expert panel who drafted this consensus statement. Pediatric stenosis with complete tracheal rings could become a very critical
surgery, anesthesia, critical care medicine, cardiothoracic surgery, patient after a simple bronchoscopy, when mucosal edema occurs
radiology, were all considered as non core disciplines, available for on an already reduced tracheal lumen. In this situation, the only
sporadic consultations. In our Institution, instead, the presence of way to oxygenate the patient could be ECMO and tracheal stenosis
all these is considered as essential for the discussion of all cases at repair become an emergency procedure.
the weekly meeting. A number of other disciplines and non medi- Is an airway team required in all hospitals? In our opinion, it
cal members are deemed essential for the team (speech therapist, depends on the kind of hospital it is. If the hospital is a tertiary
sleep medicine, respiratory therapist, dietician, occupational ther- referral center, treats often premature babies, has cardiac surgery,
apy, social workers, etc..) that are probably available in all US hos- attracts patients from all Country or elsewhere for surgical repairs,

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M. Torre, R. D’Agostino, I. Fiz et al. Seminars in Pediatric Surgery 30 (2021) 151051

it is probably logical to set an airway team, as there will be the first years of airway activity. Thanks to this community (that was
need to treat airway patients and it is usually more convenient called “Airway Family”), it was easier for everyone of us to over-
to do it on your own than to send them elsewhere. If the center come the natural fear of making new difficult things and the frus-
is smaller, there is no cardiac surgery, or there is another airway tration whenever something was not going perfectly well. It was
team already established near to you, it is probably not logical to natural for us to celebrate the successes with the others and ask
make the big effort of creating another airway team. for opinions in case of doubt. Many of us travelled to other places
Which criteria should an airway team have, how many airway to help other surgeons in difficult cases. In our opinion this factor
teams should exist per habitant or per Country and which patients was something difficult to find among surgeons, who are more of-
should be treated in an airway team center only remain to be de- ten in a mood of competition more than of assistance towards the
termined at a political level. Establishing these criteria by public others colleagues.
health managers could help significantly the care of these chil-
dren. In UK, health authorities recognized the reported reduction Future directions
of costs thanks to centralized care of the difficult airway patients10
and established that every pediatric patient with complex tracheal Airway surgery is a rapidly evolving matter, as are all medicine
diseases has to be referred to GOSH tracheal team. The fact that fields. We can expect big changes in the management of these pa-
centralization of care in tracheal surgery helps to improve the out- tients, thanks to new technology and scientific progress. Regarding
comes and reduce the costs is probably true not only in United the topic of the paper, focused on teamwork, the trend and the
Kingdom, but centralization of uncommon and challenging patients efforts are towards the implementation of a worldwide network
is far from the usual habit in the management of airway patients of airway teams. INPAT (International Network of Pediatric Airway
in many geographical areas. In the future, a lot of efforts should Teams) is a recently born network of airway teams from every part
be spent in this direction if we hope to change the outcomes of of the world, that gathered already twice in Italy (Genoa in 2017
airway patients. It is well known, in fact, that the first treatment and Rome in 2019) in multidisciplinary meetings organized thanks
is the most important for the final outcome, and for this reason to the sinergy between two big Italian pediatric hospital (Giannina
every airway patient should be referred initially in a team with Gaslini and Bambino Gesù). The background that led to create IN-
established airway team and not only in case of unsuccess after PAT was a community of people with multiple specializations but
the first attempt. It would be probably better to establish clear, all interested in pediatric airway, interacting between them and
measurable and widely accepted criteria for dividing the centers in sharing clinical cases thanks to social media and Apps.
those which can treat all kind of problems and those which should INPAT was a useful tool to launch multicenter studies on rare
better refer the patients elsewhere. conditions, as demonstrated by the paper on pediatric airway tu-
It can be questionable if in a single institution it is necessary to mors.12 On clinical research corner, other multicenter networks
determine by default which should be the area of action of the sin- and groups were able to work together on specific airway topics
gle professionals or if this can be left unregulated. In other worlds, in order to establish common goals, protocols or consensus state-
is it necessary to regulate diagnostic and therapeutic pathways in ments.13 , 14
order to avoid that more professionals do the same procedure in If in the past the challenge for the single Institutions was the
the same hospital? To divide the tasks between different profes- creation of an airway team, now it is the time for all the airway
sionals can be not easy (someone has to renounce to do some- team to cooperate and work as a “team of teams”, thus multiplying
thing) and could raise (more or less open) argues, but in our opin- the benefits of the teamwork on a worldwide scale.
ion it is convenient for the following reason: in the same hospital
both for the patient and the administration it is more simple and Acknowledgements
clear to have single and definite more than multiple and different
pathways. Moreover, if every single professional has a definite own Thanks to Dr. Pietro Tuo who wanted strongly to set up an air-
area of expertise, he will have more responsibility and the possibil- way team in our hospital and all who cooperated to make it pos-
ity to become the real expert in this field. To have restricted area sible
of action give to each one a more focused objective and can help Thanks to Claudia Schweiger and Patricio Varela for revising
to become excellent in the field.11 and improving the manuscript. A special thanks to Philippe Mon-
A final comment is reserved to the sprouting of new airway nier for his unique dedication to help our team and many others
teams in many parts of the world. As said above, this need is com- in the world.
mon in many contexts, however, it can be surprising that this pro- Thanks to all the members of Airway Family, in every part of
cess was so successful in so many cases, although all the difficul- the world they are
ties presented. In our opinion, the teamwork on airway patients
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