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7kuliah Ke 7 Pubertas
7kuliah Ke 7 Pubertas
Pubertas
Perbedaan Fundamental antara jantan dan betina
Pulse
Patterns
Surge + Tonic
Tonic
Pubertas
• Kemampuan menjalankan proses reproduksi.
Hormonal Genetic
Puberty
Environment Nutritional
Hormonal
• Puberty
» increase in the pulse frequency and amplitude of
GnRH release
» increase in FSH and LH pulses
» folliculargenesis and spermatogenesis occur
Perubahan Hormonal pada betina
Sekresi GnRH dari Hypothalamic
Low Amplitude
and Frequency
Sekresi GnRH dari Hypothalamic
Senger, 2012
Sekresi GnRH dari Hypothalamic
Pattern!!
Senger, 2012
Surge
Tonic
Regulator GnRH Pulses saat Pubertas
Puberty =
28 - 30 weeks
Development of
the
Hypothalamic
GnRH Surge
Center
Puberty =
28 - 30 weeks
Positive
Feedback is
possible prior
to puberty
Changes in Feedback Sensitivity to Estradiol
3
LH (ng/ml)
0 1 2 3 4 5 6 7 8 9 10 11
Time (hours)
Effect of 2-deoxyglucose on LH Pulses
GnRH
Before 2DG During 2DG
3
LH (ng/ml)
0 1 2 3 4 5 6 7 8 9 10 11
Time (hours)
10 2.0 lb/day
8
1.2 lb/day
6
0
0 4 8 12 16 20 24
Age (months)
% Berat dewasa saat Pubertas
24 Weeks
24 Weeks
Pengaruh tingkat pertumbuhan dan keberadaan
pejantan terhadap umur pubertas
300
200
100
0
Hanya Heifers Bersama jantan
Mechanism pengaruh Social
• Pheromones
• Impacts on GnRH
» Nasal receptors impact nerve tracts to the
hypothalamus
Hormonal Genetic
Puberty
Environment Nutritional
Recommended Age to Breed
• Heifer 15 months (65% mature BW)
• Gilt 8 – 9 months
• Boar 9 months