1.

Introduction to Cell Physiology

Learning Objectives Upon completion of this chapter, you will be able to:
1. Identify the parts of the human cell.
2. Describe the role of each organelle found within the cell cytoplasm.
3. Explain the unique properties of the cell membrane.
4. Describe three processes used by the cell to move things across the cell membrane.
5. Outline the cell cycle, including the activities going on within the cell in each phase.

 THE CELL
 Cell Nucleus
 Cell Membrane, Lipoproteins, Receptor Sites, Identifying Markers, Channels
 Cytoplasm, Mitochondria, Endoplasmic Reticulum, Free Ribosomes, Golgi
Apparatus, Lysosomes
 CELL PROPERTIES, Endocytosis, Exocytosis
 Homeostasis
 Passive Transport, Diffusion, Osmosis, Facilitated Diffusion
 Active Transport
 CELL CYCLE
 G0 Phase
 G1 Phase
 S Phase
 G2 Phase
 M Phase

2. Antibiotics
Introduction
BACTERIA AND ANTIBIOTICS
BACTERIA AND RESISTANCE TO ANTIBIOTICS
AMINOGLYCOSIDES

 Therapeutic Actions and Indications

 Pharmacokinetics
 Contraindications and Cautions
 Adverse Effects
 Clinically Important Drug–Drug Interactions
 Nursing Considerations for Patients Receiving Aminoglycosides

CARBAPENEMS
  Therapeutic Actions and Indication
 Pharmacokinetics
 Contraindications and Cautions
 Adverse Effects
 Clinically Important Drug–Drug Interactions
 Nursing Considerations for Patients Receiving Carbapenems

CEPHALOSPORINS

 Therapeutic Actions and Indications

 Pharmacokinetics
 Contraindications and Cautions
 Adverse Effects
 Clinically Important Drug–Drug Interactions
 Nursing Considerations for Patients Receiving Cephalosporins

FLUOROQUINOLONES

 Therapeutic Actions and Indications

 Pharmacokinetics
 Contraindications and Cautions
 Adverse Effects
 Clinically Important Drug–Drug Interactions
 Nursing Considerations for Patients Receiving Fluoroquinolones

PENICILLINS AND PENICILLINASERESISTANT ANTIBIOTICS

 Therapeutic Actions and Indications

 Pharmacokinetics
 Contraindications and Cautions
 Adverse Effects
 Clinically Important Drug–Drug Interactions
 Nursing Considerations for Patients Receiving Penicillins and Penicillinase-
Resistant Antibiotics

SULFONAMIDES

 Therapeutic Actions and Indications

 Pharmacokinetics
 Contraindications and Cautions
 Adverse Effects
 Clinically Important Drug–Drug Interactions
 Nursing Considerations for Patients Receiving Sulfonamides

TETRACYCLINES
  Therapeutic Actions and Indications
 Pharmacokinetics
 Contraindications and Cautions
 Adverse Effects
 Clinically Important Drug–Drug Interactions
 Nursing Considerations for Patients Receiving Tetracyclines

ANTIMYCOBACTERIALS
- ANTITUBERCULOSIS DRUGS
- LEPROSTATIC DRUGS

 Therapeutic Actions and Indications

 Pharmacokinetics
 Contraindications and Cautions
 Adverse Effects
 Clinically Important Drug–Drug Interactions
 Nursing Considerations for Patients Receiving Antimycobacterials

OTHER ANTIBIOTICS
- KETOLIDES

 Therapeutic Actions and Indications

 Pharmacokinetics
 Contraindications and Cautions
 Adverse Effects
 Clinically Important Drug–Drug Interactions

- LINCOSAMIDES

 Therapeutic Actions and Indications

 Pharmacokinetics
 Contraindications and Cautions
 Adverse Effects
 Clinically Important Drug–Drug Interactions

- LIPOGLYCOPEPTIDES

 Therapeutic Actions and Indications

 Pharmacokinetics
 Contraindications and Cautions
 Adverse Effects
 Clinically Important Drug–Drug Interactions

- MACROLIDES
  Therapeutic Actions and Indications
 Pharmacokinetics
 Contraindications and Cautions
 Adverse Effects
 Clinically Important Drug–Drug Interactions

- MONOBACTAM ANTIBIOTIC

 Therapeutic Actions and Indications

 Pharmacokinetics
 Contraindications and Cautions
 Adverse Effects
 Clinically Important Drug–Drug Interactions

Nursing Considerations for Patients Receiving Other Antibiotics

NEW ANTIBIOTICS AND ADJUNCTS