TARLAC STATE UNIVERSITY

COLLEGE OF SCIENCE
DEPARTMENT OF NURSING
Awarded Level III Status by the Accrediting Agency of Chartered Colleges and Universities in the Philippines

Name: Manalo, Joshua A. Date: 08/25/21

Section/Group: BSN-2B, G3
DRUG STUDY
DOSAGE,
MECHANISM OF SIDE EFFECTS, NURSING
NAME OF THE DRUG ROUTE, AND INDICATION CONTRAINDICATION
ACTION ADVERSE EFECTS RESPONSIBILITIES
FREQUENCY
Drug name: Stock dose:  Anti- Precaution:  Contraindicated in SIDE EFFECTS: BEFORE:
Methylprednisolone Per Orem (OP) inflammatory:  Hypersensitivity to patients  Frequent:  Check Doctor’s order
Suppresses methylprednisolone. hypersensitive to Insomnia,  Question for
Brand name: Intravenous (IV) migration of Administration of drug or its heartburn, hypersensitivity to any
Medrol, Dosepak, polymorphonuclear live or attenuated ingredients, in anxiety, of the corticosteroids,
DepoMedrol, and MAINTENANCE leukocytes, virus vaccines, those with systemic abdominal components.
SoluMedrol DOSE reverses increased systemic fungal fungal distention,  Obtain baselines for
CHILDREN: capillary infection. infections, in diaphoresis, acne, height, weight, B/P,
Classification: OP: Initially, permeability. premature infants mood swings, serum glucose,
Anti-inflammatory, 0.11– 1.6 Exerts effects on (acetate and increased appetite, electrolytes.
Immunosuppressive, mg/kg/day in 3–4 modulating succinate), and in facial flushing, GI  Check results of initial
corticosteroids divided doses. carbohydrate, patients receiving distress, delayed tests (tuberculosis
Range: 0.5–1.7 protein, lipid immunosuppressive wound healing, [TB] skin test, X-rays,
Pregnancy Category: mg/kg/day in 2–4 metabolism. doses together with increased ECG).
C divided doses. Maintains live-virus vaccines. susceptibility to  Question history as
fluid/electrolyte  Use cautiously in infection, listed in Precautions.
Image: IV: 0.5–1.7 hemostasis. patients with GI diarrhea,
mg/kg/day or 5–25 Influences CV, ulceration or renal constipation. DURING:
mg/m2/day in 2–4 immunologic, disease,  Check vital signs at
divided doses. endocrine, hypertension,  Occasional: least twice daily.
musculoskeletal, osteoporosis, Headache, edema,  Monitor serum
neurologic diabetes tachycardia, electrolytes, including
physiology. change in skin B/P, glucose.
 mellitus, color, frequent  Monitor for
THERAPEUTIC hypothyroidism, urination, hypocalcemia (muscle
EFFECT: cirrhosis, depression. twitching, cramps,
Decreases diverticulitis, positive Trousseau’s or
inflammation. nonspecific  Rare: Psychosis, Chvostek’s signs),
ulcerative colitis, increased blood hypokalemia
 PEAK recent intestinal coagulability, (weakness, muscle
PO: anastomoses, hallucinations. cramps, numbness,
2- 3 hrs thromboembolic tingling [esp. lower
IV: disorders, seizures, ADVERSE extremities],
Price Range: N/A, Immediate active hepatitis, EFFECTS: nausea/vomiting,
₱40.50 - ₱70.75 myasthenia gravis,  Long-term irritability, ECG
16mg 1 Tablet  ONSET HF, TB, ocular therapy: changes).
[PRESCRIPTION PO: herpes simplex, Hypocalcemia,
REQUIRED] Rapid emotional hypokalemia, AFTER:
IV: instability, and muscle wasting  Assess emotional
Rapid psychotic (esp. in arms, status, ability to sleep.
tendencies. legs),  Check lab results for
 DURATION  Prolonged use may osteoporosis, blood coagulability,
PO: increase risk of spontaneous clinical evidence of
30-36 hrs infection, mask fractures, thromboembolism.
IV: signs of infection, amenorrhea,  Monitor I&O, daily
1 wk and activate latent cataracts, weight; assess for
infections. glaucoma, peptic edema.
ulcer, HF.  Monitor daily pattern
of bowel activity, stool
 Abrupt consistency.
withdrawal after  Be alert for infection
long-term (sore throat, fever,
therapy: vague symptoms).
Anorexia, nausea,
fever, headache,
severe arthralgia, HEALTH TEACHINGS:
rebound  Take oral dose with
inflammation, food, milk.
fatigue, weakness,
lethargy,  Do not change
dizziness, dose/schedule or stop
orthostatic taking drug; must taper
hypotension. off gradually under
medical supervision.
 Report fever, sore
throat, muscle aches,
sudden weight gain or
loss, edema, loss of
appetite, fatigue.
 Maintain strict
personal hygiene;
avoid exposure to
disease, trauma.
 Severe stress (serious
infection, surgery, and
trauma) may require
increased dosage.
 Follow up visits, lab
tests are necessary.
 Children must be
assessed for growth
retardation.
 Inform dentist, other
physicians of
methylprednisolone
therapy now or within
past 12 mos.
REFERENCE:
Medrol (Methylprednisolone): Uses, Dosage, Side Effects, Interactions, Warning. (2020, May 20). RxList. https://www.rxlist.com/medrol-drug.htm#dosage

Methylprednisolone Pregnancy and Breastfeeding Warnings. (n.d.). Drugs.Com. Retrieved August 25, 2021, from

https://www.drugs.com/pregnancy/methylprednisolone.html

Bs, R. K. J., RPh, & Ccrn, H. K. R. B. (2020). Saunders Nursing Drug Handbook 2021, 1e (1st ed.). Saunders.

Kluwer, W. (2017). Nursing Drug Handbook 2018 (38th ed.). Wolters Kluwer Health.

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