Course Code: MEDT 07

Course Title: Cytogenetics

Instructor: Stephanee R. Gramonte, RMT

Course Description:

This course deals with the study of the concepts related to the study of heredity and inheritance: genetic phenomena, sex determinations,
defects in relation to human inheritance. Nucleic acids (DNA and RNA) and their application to medical science are given emphasis.

Evaluation of Students Performance/Grading

100% Lecture
 Quizzes and Major Examinations - 60%
 Portfolios (Assignment, Recitation, Report, etc.) - 30%
 Class Participation - 10%

Program Outcomes Addressed by the Course

After completing this course, the students must be able to:
1. identify the chemical and physical nature of the genetic materials present in parents that are transmitted to the offspring.
2. realize that gene is the basic unit of heredity that shares the properties of function, recombination and mutation
3. think critically and discuss the effect of changes in the environment and how these changes affect various living system.
4. apply principles and concepts of genetics in Medical Technology practice

5. integrate the scientific ethics and humanistic values when dealing with application of genetics in everyday life
College Vision

The College of Nursing of Cavite State University envisions being one of the nation’s leading nursing institutions in providing
excellent instruction and opportunities for research, practice, and service.

College Mission

The mission of College of Nursing is to educate students, advance the discipline of nursing through research, provide service
that is responsive to the health care needs of the public, and demonstrate local, national and international leadership for the
profession.

College Goals

The College of Nursing shall endeavor to achieve the following goals:

1. produce technically and scientifically oriented graduate imbued with a deep sense of professionalism, possess strong
social consciousness, and guided by positive values and high ethical standard;
2. conduct evidence-based research and extension services towards the provision of safe, holistic and quality nursing
care;
3. implement effective training and outreach programs that emphasize self-help; critical thinking and lifelong learning;
and
4. establish strong linkage with non-governmental organization, other government entities and the community at large for
the realization of the common goals.
Online Class Guidelines

Students are required to:

1. sign an honor system pledge;
2. avoid giving or receiving unauthorized aid of any kind on their examinations, papers, projects and assignments,
3. observe proper netiquette during on-line activities, and submit take home assignments on time.

Netiquette guidelines

1. Time is gold
Be early. It’s always a good etiquette to join the video conference 15 minutes before it starts. Sometimes the schedule will not start as
planned but that doesn’t excuse us from not doing the right thing - Be on time. Upon joining, mute yourselves for the courtesy of others
especially if your place creates a lot of sound.

2. Neatness is attractive
When attending a video conference wear appropriate attire. Fix your hair and bring out your smile.
No unnecessary actions should be done that might distract other from listening. You don’t wan to feel the same.
Do behave in front of the camera as if you’re the star of the show

3. NO YELLING, PLEASE
There’s a time and a place for everything—BUT IN MOST SITUATIONS TYPING IN ALL CAPS IS INAPPROPRIATE. Most readers
tend to perceive it as shouting and will have a hard time taking what you say seriously, no matter how intelligent your response may
be.

4. Sarcasm can (and will) backfire

Sarcasm has been the source of plenty of misguided arguments online, as it can be incredibly difficult to understand the commenter’s
intent. What may seem like an obvious joke to you could come across as off-putting or rude to those who don’t know you personally.
As a rule of thumb, it’s best to avoid sarcasm altogether in an online classroom. Instead, lean toward being polite and direct in the way
you communicate to avoid these issues.

5. Don’t abuse the chat box

The class chat box isn’t an instant messenger like you’d use with friends. Treat it like the learning tool it’s meant to be, and try not to
distract your classmates with off-topic discussions.
6. Attempt to find your own answer
If you’re confused or stuck on an assignment, your first instinct may be to immediately ask a question. But before you ask, take the
time to try to figure it out on your own. Attempt to find the answers to any other questions on your own using a search engine. If your
questions remain unanswered after a bit of effort, feel free to bring them up with your instructor.

7. Stop ... grammar time!

Always make an effort to use proper punctuation, spelling and grammar. Trying to decipher a string of misspelled words with erratic
punctuation frustrates the reader and distracts from the point of your message. On the other hand, it’s important to be reasonable
about others’ grammar mistakes. Nobody likes the grammar police, and scolding a classmate because he or she used “your” instead
of “you’re” isn’t practicing proper netiquette.

8. Set a respectful tone

Every day may feel like casual Friday in an online classroom where you don’t see anyone in person, but a certain level of formality is
still expected in your communication with instructors. In addition to proper punctuation and spelling, it’s good netiquette to use
respectful greetings and signatures, full sentences and even the same old “please” and “thank you” you use in real life.

9. Submit files the right way

You won’t be printing assignments and handing to them to your teacher in person, so knowing how to properly submit your work online
is key to your success as an online student. Online course instructors often establish ground rules for file assignment submissions, like
naming conventions that help them keep things organized or acceptable file formats. Ignoring these instructions is a common example
of bad netiquette. If you don’t follow instructions, you’re taking the risk that your instructor won’t be able to find or open your
assignment. Save yourself and your instructor a headache and read their instructions carefully before submitting.

10. Read first

Take some time to read through each of the previous post instructions and responses before writing your own response. The instructor
may think you are not paying attention if you repeat the same response or question. Better read first.

11. Think before you type

A passing comment spoken in class can be forgotten a few minutes later, but what you share in an online classroom is part of a
permanent digital record. “Whether or not privacy settings are in place, the internet has a tendency to house things forever, and what
you say privately can easily become public,” advises etiquette expert Devoreaux Walton.
Not only is it good practice to be guarded when it comes to personal information, you always want to be just as respectful toward
others as you would be if you were sitting in the same room together.
12. Be kind and professional
Online communication comes with a level of anonymity that doesn’t exist when you’re talking to someone face-to-face. Sometimes this
leads people to behave rudely when they disagree with one another. Everyone probably don’t have the complete anonymity that
comes with using a screen name, but you could still fall prey to treating someone poorly because of the distance between screens.
Make a point to be kind and respectful in your comments—even if you disagree with someone.
“At the core, all of these mistakes come down to forgetting that an online classroom is still a classroom,” Lynch says. “Good netiquette
means conducting yourself in an online class with the same respect, politeness and professionalism that you would exhibit in a real-life
classroom.”

REFERENCES AND SUPPLEMENTARY READINGS

Camara, J. S. & Oclay, A.D.S. (1998). Cytogenetics: principles and applications.1st ed. Dagupan City, Philippines: Space Browser
Publishing.
Guerrero, J. J., et al. (2016). Principles of cytogenetics. 1st ed. Malabon, Philippines: Educational Publishing House.
Hartl, D. L. & Jones, E. W. (1998). Genetics principles and analysis, 4th ed. Sudburry, Massachusetts: Jones and Barlett Publishers.
Hubbard, J. D. (2010). A concise review of clinical laboratory science. Philadelphia: Lippincott, Williams & Wilkins.
Lewis, R. (2013). Human genetics concepts and applications. 10th ed. Penn Plaza, New York: McGraw-Hill Global Education
Holdings.
McPherson, R. A. & Pincus, M. R. (2011). Henry’s clinical diagnosis and management by Laboratory Methods. 22nd ed. Philadelphia,
PA: Elsevier Saunders.
Pal, G. P. (2017). Medical genetics. 3rd ed. Krishan Nagar, Delhi: AITBS Publishers, India.

Electronic References:
www.google.com (for some illustrations and audio-visual presentations)
Supplementary Readings
Compilation of lecture/notes
 September 9, 2020 September 16, 2020
ORIENTATION
I. Introduction
1. Origin and Importance of
Genetics
Branches of Genetics
II. Introduction to Cytology
1. Review of Cell Structure and
Function
2. Mitosis
Meiosis
October 7, 2020 October 14, 2020
Activities
3. Non-Mendelian Inheritance
Deadline: Next meeting
4. Patterns of Inheritance
5. Pedigree Analysis
Quiz
1 hour during our time
November 4, 2020 November 11, 2020
V. The Genetic Material
1. Deoxyribonucleic Acid
(DNA)
2. Ribonucleic Acid (RNA)
MIDTERM EXAM
September 23, 2020 September 30, 2020
III. Mendelian and
Non-Mendelian Inheritance
Activities 1. Basic Terminologies
Deadline: Next meeting 2. Mendelian Inheritance
A. Mendel’s experiments
Quiz B. Mendelian Laws of
1 hour during our time Inheritance
C. Test Cross and Punnett
Square
October 21, 2020 October 28, 2020
IV. Chromosomes
1. Human Chromosomes
Classification of
Activities
Chromosomes
Deadline: Next meeting
2. Chromosome Analysis
A. Karyotyping
Quiz
B. Chromosome Banding
1 hour during our time
C. Fluorescent In Situ
Hybridization
D. Microarray Technology
November 18, 2020 November 25, 2020
VI. The Central Dogma of
Activities
Molecular Biology
Deadline: Next meeting
1. DNA Replication
2. Transcription
Quiz
3. Translation
1 hour during our time
 December 2, 2020 December 9, 2020 December 16, 2020 December 23&30, 2020
Activities Activities
Deadline: Next meeting VII. Variation and Mutation Deadline: Next meeting
1. Genetic Disorders
Quiz Quiz
1 hour during our time 1 hour during our time
January 6, 2020 January 13, 2020 January 20, 2020 January 27, 2020

Assessment &
2. Genetic Engineering/
Recombinant DNA Review Time
Technology (check your status. Have I
3. Gene Therapy and successfully submitted all the
Gene Editing requirements? Did I forget to
submit an activity?)
FINAL EXAM