Professional Documents
Culture Documents
2. Antiretroviral agents in pre- Pre-exposure prophylaxis (or PrEP) is a way for Anteneh, B., Belachew, S. A.,
exposure prophylaxis: people who do not have HIV but who are at very Endeshaw, A., Wubneh, Z. B.,
emerging and advanced high risk of getting HIV to prevent HIV infection by & Sarkar, B. R. (2019).
trends in HIV prevention taking a pill every day. Several studies have shown Knowledge, attitude and
that ART PrEP prevents HIV acquisition from sexual, practices of medical and
blood and mother-to-child transmissions. health science students on the
antiretroviral based HIV post-
exposure prophylaxis in an
Ethiopian hospital: An
institutional based cross-
sectional study. BMC Health
Services Research, 19(1).
doi:10.1186/s12913-019-
Group 2 – Gabriel, Abeleda, Serafin, Dorongon, Rivera PHRES4
4611-2
3. Clinical and Economic Effects Pharmacists have demonstrated the ability to Dilworth, T. J., Klein, P. W., Mercier,
of a Pharmacist-Administered improve patient adherence to antiretroviral R., Borrego, M. E., Jakeman,
Antiretroviral Therapy therapy (ART). In their study, a pharmacy B., & Pinkerton, S. D. (2018).
Adherence Clinic for Patients adherence clinic that focused on early and Clinical and Economic Effects
Living with HIV sustained ART adherence interventions helped of a Pharmacist-Administered
patients with documented medication adherence Antiretroviral Therapy
problems achieve an undetectable HIV RNA. This Adherence Clinic for Patients
led to high cost savings for HIV patients. Living with HIV. Journal of
Managed Care & Specialty
Pharmacy, 24(2), 165-172.
doi:10.18553/jmcp.2018.24.2.
165
4. HIV Pharmacist's Impact on HIV pharmacist monitoring can reduce medication Liedtke, M., Tomlin, C., Skrepnek,
Inpatient Antiretroviral Errors errors in HIV-infected patients as they transition G., Farmer, K., Johnson, P., &
between out-patient and in-patient care. Rathbun, R. (2016). HIV
Pharmacist's Impact on
Inpatient Antiretroviral Errors.
HIV Medicine, 17(10), 717-
723. doi:10.1111/hiv.12375
5. Knowledge and Attitude on Findings of the study revealed a high level of Galindo, M. Q. (2016). Knowledge
HIV and AIDS: Standpoint of knowledge on HIV/ AIDS and a moderately positive and Attitude on HIV and AIDS:
College Students of the attitude towards all the aspects involved in dealing Standpoint of College
University of the Immaculate with these health issues. It was found that there is Students of the University of
Conception a significant moderate relationship between the the Immaculate Conception.
Group 2 – Gabriel, Abeleda, Serafin, Dorongon, Rivera PHRES4
knowledge and attitude on HIV/AIDS from the UIC Research Journal, 20(1).
standpoint of the college students. doi:10.17158/550
6. Life Expectancy Simulation Their study results revealed that there is an Castro, M. D., Villanueva, T., &
Model among HIV (Human increased lifespan of about six (6) folds of HIV Gonzalve, R. (2017). Life
Immunodeficiency Virus)- infected individuals who seek treatment Expectancy Simulation Model
Infected Individuals: A Monte (antiretroviral therapy) than those otherwise. The among HIV (Human
Carlo Approach expected average lifespan of individuals being Immunodeficiency Virus)-
treated ranges 38-66 years that is greater than Infected Individuals: A Monte
those without treatment of 5-11 years from Carlo Approach. Recoletos
individuals who do not seek treatment. Multidisciplinary Research
Journal, 2(2), 9-18.
doi:10.32871/rmrj1402.02.02
7. Effect of age at initiation of The proportion of young adults and patients at Ssebutinde, P., Kyamwanga, I.,
antiretroviral therapy on WHO stage I initiating ART increased steadily over Turyakira, E., Asiimwe, S., &
treatment outcomes; A the 7-year period. Older age at ART initiation (> = Bajunirwe, F. (2018). Effect of
retrospective cohort study at 50 years) was associated with a higher risk of age at initiation of
a large HIV clinic in mortality with adjusted relative risk (RR) at 1.63, antiretroviral therapy on
southwestern Uganda (95% CI 1.26–2.11) compared to younger age. Male treatment outcomes; A
gender, WHO stages III and IV, lower CD4 count retrospective cohort study at
and lower body mass index were also all large HIV clinic in southwester
independently and significantly associated with Uganda.
higher risk for mortality. Older adults also had a
poorer immunological response RR = 1.79 (95% CI
0.89–3.58) but was not statistically significant.
8. Antiretroviral Treatment Despite having good knowledge about ART, AYAs Hornschuh, S., Dietrich, J.J.,
Adherence: Knowledge and may face circumstances which can derail optimal Tshabalala, C., Laher, F.
Experiences among adherence. AYAs may present with specific Antiretroviral Treatment
Adolescents and Young Adults adherence problems, such as denial about HIV Adherence: Knowledge and
in Soweto, South Africa persistence after a childhood of treatment and the Experiences among
issues that HIV/AIDS poses to them during a phase Adolescents and Young Adults
of development in which social assimilation gains in Soweto, South Africa
prominence in their lives. AYAs may find it difficult
to open up about these circumstances as they
struggle internally to resolve them. It may be useful
for the healthcare practitioner facing a poorly
adherent AYA patient to learn from the strategy we
employed in our interviews: inviting AYAs to share
general, not necessarily personal, barriers to
adherence. Regardless, in a world where HIV
discrimination remains a reality, secretiveness may
be a practical and palatable strategy which a
healthcare worker can suggest to AYAs to help
maintain adherence while public disclosure is
unthinkable for the individual. Parallel
interventions may be motivational messaging
focusing on the known long-term health, longevity,
and prevention benefits of achieving viral
suppression through adherence and practical
strategies for status disclosure where appropriate
Group 2 – Gabriel, Abeleda, Serafin, Dorongon, Rivera PHRES4
9. A review of HIV antiretroviral This review indicates that more research on S. L. Reisner, M. J. Mimiaga, M.
adherence and intervention adherence among HIV-infected youth, as well as Skeer, B. Perkovich, C. V.
studies among HIV-infected more rigorously evaluated interventions, are Johnson, and S. A. Safren, “A
youth needed. Maximizing adherence may not only be review of HIV antiretroviral
fundamental to the wellbeing of HIV-infected adherence and intervention
youth but may also have a far-reaching and studies among HIV-infected
broader impact on public health. No adherence youth,” Topics in HIV
may lead to drug resistance and cross-resistance Medicine, vol. 17, no. 1, pp.
that may render HIV treatments ineffective and 14–25, 2009.
may be implicated in the emergence of drug-
resistant strains of HIV. Consequently, gaining a
more thorough and contextualized understanding
of factors associated with adherence and no
adherence, including individual demographic,
social and psychologic, disease-related, treatment-
regimen, and practitioner factors, represents an
important step in helping people live longer and in
intervening to address infectious disease rates.
Further culturally tailored, intervention
development research for HIV-infected youth is
warranted.
10. Evaluation of HIV/AIDS Despite substantial evidence that antiretroviral Almeida, R.F. & Vieira, A.P. (2009).
patients' knowledge on therapy is potentially effective in reducing viral Evaluation of HIV/AIDS
antiretroviral drugs load and the postponement of the onset of patients' knowledge on
opportunistic diseases, recent data indicates that antiretroviral drugs.
approximately half of patients receiving this
medication fail to follow the prescription.
11. Gender affirmative HIV care There exist mixed regimens and beliefs about Arjee J. Restar, E. Karina
framework: Decisions on taking FHT and ART among this sample of trans Santamaria, Alexander Adia,
feminizing hormone therapy women. While trans participants’ main source of Jennifer Nazareno, Randolph
(FHT) and antiretroviral health information is their HIV provider, providers Chan, Mark Lurie, Theo
therapy (ART) among are likely to communicate non-affirmative rhetoric Sandfort, Laufred Hernandez,
transgender women that negatively impacts trans women’s decision to Susan Cu-Uvin & Don
take FHT and ART. Research is needed to elucidate Operario. (2019) Gender
co-prescriptions of gender-affirmative services with affirmative HIV care
HIV care among this group in the Philippines. framework: Decisions on
feminizing hormone therapy
Exploring HIV provider-focused interventions to (FHT) and antiretroviral
improve knowledge, attitudes, and motivation to therapy (ART) among
interact with and attend to the health needs of transgender women
trans women who are living with HIV.
12. The Phenomenology of The rapid rise of HIV infections has made Ma. Francesca C. Chavez, Monica V.
Patients living with HIV: Its Philippines one of the nations in the world with a Maloles, Ma. Pamela Louise
Implications on Their Coping high risk of full-blown AIDS epidemic. Manzano (2016). The
Mechanism. Phenomenology of Patients
FGD participants view HIV as a disease that can kill living with HIV: Its Implications
them however, they still believe that knowledge on Their Coping Mechanism.
Group 2 – Gabriel, Abeleda, Serafin, Dorongon, Rivera PHRES4
13. DSM-5 substance use disorder This study examines self-reported 30-day Margaret M. Paschen-Wolff, Aimee
symptom clusters and HIV antiretroviral therapy (ART) adherence among 101 N.C. Campbell, Susan Tross,
antiretroviral therapy (ART) people living with HIV and substance use disorders Tse-Hwei Choo, Martina
adherence (SUD) in New York City in terms of Diagnostic and Pavlicova & Don Des Jarlais
Statistical Manual – 5th Edition (DSM-5) SUD (2020) DSM-5 substance use
symptom clusters: impaired control, social disorder symptom clusters
impairment, risky use and pharmacological criteria. and HIV antiretroviral therapy
Participants with vs. without alcohol SUD were (ART) adherence, AIDS Care,
significantly less likely to report ART adherence 32:5, 645-650, DOI:
(64.3% vs. 88.2%, p = .017). Endorsement of social 10.1080/09540121.2019.1686
impairment significantly differed among adherent 600
vs. non-adherent participants with alcohol SUDs
(74.1% vs. 100%, p = .038) and with opioid SUDs
(94.1% vs. 50.0%, p = .040). Understanding specific
SUD symptom clusters may assist providers and
patients in developing strategies to improve ART
adherence.
14. Disability and health Long-term survival with HIV is associated with new Myezwa H, Hanass-Hancock J,
outcomes – from a cohort of health-related issues and a risk of functional Ajidahun AT, Carpenter B.
Group 2 – Gabriel, Abeleda, Serafin, Dorongon, Rivera PHRES4
15. The HIV Treatment Gap: AIDS has killed 39 million people since 1981, and Dutta A, Barker C, Kallarakal A
Estimates of the Financial over 36 million people (mostly living in resource- (2015) The HIV Treatment
Resources Needed versus limited countries) are currently living with HIV, the Gap: Estimates of the
Available for Scale-Up of virus that causes AIDS. HIV destroys immune Financial Resources Needed
Antiretroviral Therapy in 97 system cells (including CD4 lymphocytes), leaving versus Available for Scale-Up
Countries from 2015 to 2020 HIV-infected individuals susceptible to other of Antiretroviral Therapy in 97
infections. Their results suggest that future Countries from 2015 to 2020.
resource needs for ART scale-up are smaller than PLoS Med 12(11): e1001907.
stated elsewhere but still significantly threaten the https://doi.org/10.1371/journ
sustainability of the global HIV response without al.pmed.1001907
additional resource mobilization from domestic or
innovative financing sources or efficiency gains. As
the world moves towards adopting the WHO 2015
guidelines, advances in technology, including the
introduction of lower-cost, highly effective
antiretroviral regimens, whose value are assessed
here, may prove to be “game changers” that allow
more people to be on ART with the resources
available.
Group 2 – Gabriel, Abeleda, Serafin, Dorongon, Rivera PHRES4
16. Improving antiretroviral Those most widely studied and implemented to Haberer, J. E., Sabin, L., Amico, K. R.,
therapy adherence in date involve peer counselling, adherence clubs, Orrell, C., Galárraga, O., Tsai,
resource‐limited settings at and short message service (SMS). Many additional A. C., Vreeman, R. C., Wilson,
scale: a discussion of interventions could have an important impact on I., Sam-Agudu, N. A., Blaschke,
interventions and ART adherence with further development, T. F., Vrijens, B., Mellins, C. A.,
recommendations including standardized counselling through multi‐ Remien, R. H., Weiser, S. D.,
media technology, electronic dose monitoring, Lowenthal, E., Stirratt, M. J.,
decentralized and differentiated models of care, Sow, P. S., Thomas, B., Ford,
and livelihood interventions. Optimal targeting and N., … Bangsberg, D. R. (2017).
tailoring of interventions will require improved Improving antiretroviral
adherence measurement. therapy adherence in
The opportunity exists today to address and resource-limited settings at
resolve many of the challenges to effective ART scale: a discussion of
adherence, so that they do not limit the potential interventions and
of ART to help bring about the end of AIDS. recommendations. Journal of
the International AIDS Society,
20(1), 21371.
https://doi.org/10.7448/ias.20
.1.21371
17. High rates of retention and Increasingly, there is a need for health authority Tsondai, P. R., Wilkinson, L. S.,
viral suppression in the scale‐ scale up of successfully piloted differentiated Grimsrud, A., Mdlalo, P. T.,
up of antiretroviral therapy models of antiretroviral therapy (ART) delivery. Ullauri, A., & Boulle, A. (2017).
adherence clubs in Cape However, there is a paucity of evidence on system‐ High rates of retention and
Town, South Africa wide outcomes after scale‐up. In the Cape Town viral suppression in the scale-
health district, stable adult patients were referred up of antiretroviral therapy
to adherence clubs (ACs) – a group model of ART adherence clubs in Cape
delivery with five visits per year. By the end of Town, South Africa. Journal of
March 2015, over 32,000 ART patients were in an the International AIDS Society,
AC. We describe patient outcomes of a 20, 21649.
representative sample of AC patients during this https://doi.org/10.7448/ias.20
Group 2 – Gabriel, Abeleda, Serafin, Dorongon, Rivera PHRES4
18. HIV crisis in the Philippines: The Philippines is facing the fastest growing HIV Gangcuangco, L. A. (2019). HIV crisis
urgent actions needed epidemic in the western Pacific, with a 174% in the Philippines: Urgent
increase in HIV incidence between 2010 and 2017. actions needed (2nd ed., Vol.
Six interventions are outlined to curb the epidemic. 4, E84). The Lancet Public
First, stigma should be reduced through education. Health. doi:
Second, awareness among health-care providers https://doi.org/10.1016/S246
should be increased. Third, pre-exposure 8-2667(18)30265-2
prophylaxis (PrEP) should be distributed on a
national scale. Fourth, integrase inhibitors should
be used as first-line ART. Fifth, primary care
physicians should be empowered to provide HIV
care. Finally, substance abuse should be addressed,
and mental health promoted The HIV crisis in the
Philippines is an emergency. Youth education,
empowerment of health-care providers, national
access to PrEP and integrase inhibitors, and harm
reduction are urgently needed.
19. The Perceptions of HIV- It was clear from the discoveries of this exploration Tuhadeleni, O., Opotamutale, D.,
Positive Patients (ART that ART patients see various components as & Nuuyoma, V. (2016).
Patients) on Anti-Retroviral influencing ART adherence, including absence of The Perceptions of HIV-
Therapy (ART), Treatment cash and transport and neediness, while ART Positive Patients (ART
Supporters and Health Care center related elements remembered negative Patients) on Anti-Retroviral
Workers with Regard to their perspectives for the piece of ART facility staff, Therapy (ART), Treatment
Group 2 – Gabriel, Abeleda, Serafin, Dorongon, Rivera PHRES4
Role in ART Adherence at ART going significant distances to the ART facility and Supporters and Health Care
Clinics in the Intermediate the presence of long lines and protracted holding Workers with Regard to their
Hospital Oshakati, Namibia. up times at the facility. Role in ART Adherence at ART
Clinics in the Intermediate
Hospital Oshakati, Namibia.
20. Knowledge, attitudes, This study showed an overall good knowledge and Raberahona, M., Lidamahasolo, Z.,
perception, and practices a predominantly positive attitude/perception of Andriamamonjisoa, J. et al.
regarding antiretroviral ART. However, accurate knowledge of ART intake Knowledge, attitudes,
therapy among HIV-infected was insufficient, and the stigma associated with perception and practices
adults in Antananarivo, taking ART remained very present. Furthermore, regarding antiretroviral
Madagascar: a cross-sectional very heterogeneous practices may reflect lack of therapy among HIV-infected
survey instruction given by the physician regarding ART adults in Antananarivo,
intake. Madagascar: a cross-sectional
survey. BMC Health Serv Res
19, 341 (2019).
https://doi.org/10.1186/s129
13-019-4173-3
21. Literacy, Social Stigma, and Low literacy was a significant risk factor for Waite, K. R., BA, Orlow, M. P., MD
HIV Medication Adherence improper adherence to HIV medication regimens in MA MPH, Rintamaki, L. S.,
the study, perceived social stigma mediated this PhD, Davis, T. C., PhD, &
relationship. Low literacy HIV intervention Wolf, M. S., PhD MPH. (2008,
strategies may also need to incorporate more September 23). Literacy, social
comprehensive psychosocial approaches to stigma, and HIV medication
overcome stigma barriers. adherence. doi:
10.1007/s11606-008-0662-5
22. Knowledge, perception about The ART defaulter rate was 27% and clients had Boateng, D., Kwapong, G. D., &
antiretroviral therapy (ART) good knowledge about ART and PMTCT. More than Agyei-Baffour, P. (2013).
and prevention of mother-to- 90% of the HIV positive women had inadequate Knowledge, perception about
Group 2 – Gabriel, Abeleda, Serafin, Dorongon, Rivera PHRES4
child-transmission (PMTCT) knowledge about ART and PMTCT and these antiretroviral therapy (ART)
and adherence to ART among women were more likely to default ART. The and prevention of mother-to-
HIV positive women in the educational background of HIV positive women did child-transmission (PMTCT)
Ashanti Region, Ghana: a not have significant influence on their knowledge and adherence to ART among
cross-sectional study of ART and PMTCT. HIV positive women in the
Ashanti Region, Ghana: a
cross-sectional study. BMC
women's health, 13, 2.
https://doi.org/10.1186/1472-
6874-13-2
23. Enhancing HIV/AIDS The study shows that it will be all the more Bumanglag, K. C. (2018). Enhancing
Surveillance in the Philippines precisely deciphered, and HIV transmission HIV/AIDS Surveillance in the
to Ensure the Transgender between sexual accomplices can be all the more Philippines to Ensure the
Population's Visibility accurately reported. In this way, HIV anticipation Transgender Population's
and intercession projects can be created to all the Visibility. Enhancing HIV/AIDS
more successfully serve the given transsexual Surveillance in the Philippines
populace (transsexual ladies or transsexual men) to Ensure the Transgender
and the unsafe sexual conduct. Population's Visibility.
24. The Epidemic That We Can't The study shows that the data from the Santos, A. P. (n.d.). The Epidemic
Afford to Ignore Department of Health showed that, as of August That We Can't Afford to
2017, there were 46,985 persons living with HIV Ignore. The Epidemic That We
(PLHIV) in the Philippines. If the government does Can't Afford to Ignore.
not adjust its current HIV preventions and
treatment progs to address the complexities of the
HIV epidemic in the Philippines, the number could
triple to 142,000 by 2022. HIV in the Philippines is a
“youth epidemic." Seven out ten or about 68% of
new HIV infections are among young men or
transgender women who have sex with men are 15
to 24 years old.
Group 2 – Gabriel, Abeleda, Serafin, Dorongon, Rivera PHRES4
25. Antiretroviral for Treatment The study shows the different data and therapeutic Gunthard, H. F. (et al) (2016).
and Prevention of HIV recommendations for the use of antiretroviral Antiretroviral Drugs for
Infection in Adults: 2016 drugs (ARVs) to treat or to prevent HIV infection in Treatment and Prevention of
Recommendations of the adults. There have been substantial advances in HIV Infection in Adults: 2016
International Antiviral Society- the use of antiretroviral drugs (ARVs) for the Recommendations of the
USA Panel treatment and prevention of HIV infection. International Antiviral Society-
Antiretroviral agents remain the cornerstone of HIV USA Panel
treatment and prevention. The researchers
discussed the different revisions and
recommendations in the latest development in
ARTs.
26. Factors associated with The researchers conducted a cross sectional C.A.T. Pinheiro, J.C. de-Carvalho-
Adherence to Antiretroviral study on HIV-infected adults being treated with Leite, M.L. Drachler &V.L.
Therapy in HIV/AIDS patients: antiretroviral drugs at a reference service in Silveira (2002). Factors
a cross sectional study in Southern Brazil. It was conducted to investigate associated with Adherence to
Southern Brazil associations between the adherence to Antiretroviral Therapy in
antiretroviral therapy and sociodemographic, HIV/AIDS patients: a cross
clinical, and sociocognitive variables. The result sectional study in Southern
concluded that there was no evidence for the Brazil
association between sociodemographic
characteristics gender, age, and income and
adherence to antiretroviral medication.
27. Perception and knowledge The researchers assessed the different perception Banodita, A. D., Screshtha, N., &
about HIV/Aids among and knowledge of adolescents regarding HIV/Aids Kshitiz, U. D. (2013)
Nepalese Adolescent knowing that Nepal was confronted to its Perception and knowledge
increasing incidence rate among adolescents. The about HIV/Aids among
result regarding this research was satisfactory Nepalese Adolescent
according to the researchers. Seventy-nine percent
of the female and sixty-four percent from the male
agreed to care for HIV/Aids patients. However,
Group 2 – Gabriel, Abeleda, Serafin, Dorongon, Rivera PHRES4
Philippines Philippines has one of the fastest-growing HIV Itable, J. R. (2017) The
epidemics in the world. The reason behind this is changing molecular
because of increased testing, increased local epidemiology of HIV in the
transmission, and possibly more aggressive strains Philippines
of HIV. As HIV cases continues to increase the use
of molecular tools with clinical and demographic
data is said to be essential in providing insights into
the underlying dynamics of the epidemic being
discussed.