Amlodipine is in a class of medications called calcium channel blockers.

It lowers
blood pressure by relaxing the blood vessels so the heart does not have to pump as
hard. It controls chest pain by increasing the supply of blood to the heart.
What side effects can this medication cause?
Amlodipine may cause side effects. Tell your doctor if any of these symptoms are
severe or do not go away:
 swelling of the hands, feet, ankles, or lower legs
 headache
 upset stomach
 nausea
 stomach pain
 dizziness or lightheadedness
 drowsiness
 excessive tiredness
 flushing
this medicine can be taken morning and evening after meal.
How to take amlodipine
 All possible dosages and forms may not be included here. Your dose, form,
and how often you take it will depend on:
1. your age
2. the condition being treated
3. how severe your condition is?
4. other medical conditions you have
5. how you react to the first dose
Drug forms and strengths
Generic: Amlodipine
 Form: oral tablet
 Strengths: 2.5 mg, 5 mg, 10 mg
Brand: Norvasc
 Form: oral tablet
 Strengths: 2.5 mg, 5 mg, 10 mg
 Dosage for high blood pressure (hypertension)
 Adult dosage (ages 18–64 years)
Dosage for high blood pressure (hypertension)
 Adult dosage (ages 18–64 years)
1. Typical starting dosage: 5 mg taken once per day.
2. Dosage increases: Your doctor may change your dosage based on your blood
pressure goals. If your blood pressure is still not under control after 7–14
days of treatment, your doctor may increase your dosage.
3. Maximum dosage: 10 mg per day.
Child dosage (ages 6–17 years)
 Typical dosage: 2.5–5 mg taken by mouth once per day. Doses above 5 mg
haven’t been studied in children and shouldn’t be used.

Child dosage (ages 0–5 years)

  This drug shouldn’t be used in children younger than 6 years.

Senior dosage (ages 65 years and older)

 Typical dosage: 2.5 mg taken by mouth once per day.

 Note: Older adults may process drugs more slowly. A normal adult dosage
may cause levels of amlodipine in your body to be higher than normal. If
you’re a senior, you may need a lower dosage.

This medicine can be taken only in the morning after meal.

What else can metformin be used for?
Metformin is most commonly used to treat type 2 diabetes, either alone or
combined with other agents, but is also used off-label as a treatment for
prediabetes, gestational diabetes and PCOS.

WHAT IS METFORMIN AND HOW DOES IT WORK?

Metformin is a drug approved by the U.S. Food and Drug Administration as a
prescription medication to treat diabetes. This medication is used to decrease
hepatic (liver) glucose production, decrease GI glucose absorption and increase
target cell insulin sensitivity. This medication is a treatment indicated as an adjunct
to diet, exercise, and lifestyle changes such as weight loss to improve glycemic
(blood sugar) control in adults with type 2 diabetes. Many patients with type 2
diabetes will eventually need to take insulin by injection. Metformin does not
cause weight gain.

WHAT ARE THE DOSAGES?

Dosages of Metformin Should Be Given as Follows:

Adult Dosage Forms & Strengths for Diabetes

Tablet, immediate-release
 500 mg
 850 mg
 1000 mg
Extended-release tablet
 500 mg
 750 mg
 1000 mg
Oral solution
  500 mg
 750 mg
 1000 mg

Dosage Considerations
For Adults with Type 2 Diabetes Mellitus
 Monotherapy or with sulfonylurea
 Immediate-release tablet or solution
1. Initial dose: 500 mg orally every 12 hours or 850 mg orally once/day with
meals; increase every two weeks
2. Maintenance doses: 1500-2550 mg/day taken orally divided once every 8-
12hr with meal
3. Not to exceed 2550 mg/day
Extended-release
1. Glucophage XR: 500 mg orally once/day with dinner; titrate by 500 mg/day
each week; not to exceed 2000 mg/day
2. Fortamet: 500-1000 mg orally once/day; titrate by 500 mg/day each week;
not to exceed 2500 mg/day
3. Glumetza: 1000 mg orally once/day; titrate by 500 mg/day each week; not to
exceed 2000 mg/day

For Prevention of Type 2 Diabetes

1. 850 mg by mouth every day
2. Target dosing: 850 mg orally every 12 hours
3. Dosage Modifications
4. Hepatic (liver) impairment: Avoid use; risk of lactic acidosis.
5. Renal (kidney) impairment
6. Obtain eGFR before starting metformin
7. eGFR less than 30 mL/min/1.73 m²: Contraindicated
8. eGFR 30-45 mL/min/1.73 m²: Not recommended to initiate treatment
9. Monitor eGFR at least annually or more often for those at risk for renal
impairment (e.g., elderly)
 10.If eGFR falls below 45mL/min/1.73 m² while taking metformin, health risks
and benefits of continuing therapy should be evaluated
11.If eGFR falls below 30 mL/min/1.73 m²: while taking metformin,
discontinue the drug
12.Polycystic Ovary Syndrome (Orphan)
13.Orphan designation for the treatment of pediatric polycystic ovary syndrome

WHAT ARE SIDE EFFECTS ASSOCIATED WITH USING METFORMIN?

Side effects of metformin include:

 physical weakness (asthenia)

 diarrhea
 gas (flatulence)
 symptoms of weakness, muscle pain (myalgia)
 upper respiratory tract infection
 low blood sugar (hypoglycemia)
 abdominal pain (GI complaints), lactic acidosis (rare)
 low blood levels of vitamin B-12
 nausea
 vomiting
 chest discomfort
 chills, dizziness
 bloating/abdominal distention
 constipation
 heartburn

Effects of Drug Abuse

 There are no effects of drug abuse from the use of metformin.
Short-Term Effects
 There are no short-term effects from the use of metformin.
Long-Term Effects
  There are no long-term effects from the use of metformin.

Can be taken evening after dinner only.

Atorvastatin is used along with a proper diet to help lower "bad" cholesterol and
fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood.
It belongs to a group of drugs known as "statins."

What Is Lipitor?
Lipitor (atorvastatin) is a statin used for the treatment of elevated total cholesterol,
LDL, triglycerides, and to elevate HDL cholesterol.

What Are Side Effects of Lipitor?

 Side effects of Lipitor include:
1. constipation,
2. diarrhea,
3. nausea,
4. fatigue,
5. gas,
6. heartburn,
7. headache, and
8. mild muscle pain.
Contact your doctor if you experience serious side effects of Lipitor including:

muscle wasting and muscle breakdown (rhabdomyolysis),

confusion or memory problems,
 fever,
 dark urine,
 increased thirst or hunger,
 drowsiness,
 loss of appetite, or
 yellowing of the skin or eyes (jaundice).
  Dosage for Lipitor
The recommended dose of Lipitor is 10-80 mg daily.
What Drugs, Substances, or Supplements Interact with Lipitor?
 Erythromycin (E-Mycin), ketoconazole (Nizoral), itraconazole (Sporanox),
cyclosporine (Sand immune), indinavir (Crixivan) and ritonavir (Norvir)
decrease elimination of Lipitor. Lipitor increases the effect of warfarin
(Coumadin) and cholestyramine (Questran) decreases the absorption of
Lipitor.
Lipitor During Pregnancy and Breastfeeding
 Lipitor should not be taken during pregnancy because the developing fetus
requires cholesterol for development, and Lipitor reduces the production of
cholesterol. Lipitor passes into breast milk and could harm a nursing baby.
Breastfeeding while taking Lipitor is not recommended.
What Is Lipitor?
 Lipitor (atorvastatin) is a statin used for the treatment of elevated total
cholesterol, LDL, triglycerides, and to elevate HDL cholesterol.
What Are Side Effects of Lipitor?
 Side effects of Lipitor include:
1. diarrhea,
2. nausea,
3. fatigue,
4. gas,
5. heartburn,
6. constipation,
7. headache, and
8. mild muscle pain.
Contact your doctor if you experience serious side effects of Lipitor including:
 muscle wasting and muscle breakdown (rhabdomyolysis),
 confusion or memory problems,
 fever,
 dark urine,
  increased thirst or hunger,
 drowsiness,
 loss of appetite, or
 yellowing of the skin or eyes (jaundice).
 Dosage for Lipitor
The recommended dose of Lipitor is 10-80 mg daily.
What Drugs, Substances, or Supplements Interact with Lipitor?
 Erythromycin (E-Mycin), ketoconazole (Nizoral), itraconazole (Sporanox),
cyclosporine (Sand immune), indinavir (Crixivan) and ritonavir (Norvir)
decrease elimination of Lipitor. Lipitor increases the effect of warfarin
(Coumadin) and cholestyramine (Questran) decreases the absorption of
Lipitor.
Lipitor During Pregnancy and Breastfeeding
 Lipitor should not be taken during pregnancy because the developing fetus
requires cholesterol for development, and Lipitor reduces the production of
cholesterol. Lipitor passes into breast milk and could harm a nursing baby.
Breastfeeding while taking Lipitor is not recommended.
Get emergency medical help if you have signs of an allergic reaction: hives;
difficulty breathing; swelling of your face, lips, tongue, or throat.
 In rare cases, atorvastatin can cause a condition that results in the breakdown
of skeletal muscle tissue, leading to kidney failure. Call your doctor right
away if you have unexplained muscle pain, tenderness, or weakness
especially if you also have fever, unusual tiredness, and dark colored urine.
Also call your doctor at once if you have:
 muscle weakness in your hips, shoulders, neck, and back;
 trouble lifting your arms, trouble climbing or standing;
 liver problems--upper stomach pain, weakness, tired feeling, loss of appetite,
dark urine, jaundice (yellowing of the skin or eyes); or
 kidney problems--little or no urinating, swelling in your feet or ankles,
feeling tired or short of breath.
Common side effects may include:
  joint pain;
 stuffy nose, sore throat;
 diarrhea; or
 pain in your arms or legs.

Can be taken noon time after lunch.

What is apelit/aspirin used for?

For primary prevention of thromboembolic disorders and cardiovascular events:
Ischemic stroke; Transient ischemic attack (TIA); Acute myocardial infarction
(MI). Aspilets: Prevention of recurrent MI; Unstable angina pectoris; Chronic
stable angina pectoris.
 Aspirin is a salicylate (sa-LIS-il-ate). It works by reducing substances in the
body that cause pain, fever, and inflammation.
 Aspirin is used to treat pain, and reduce fever or inflammation. It is
sometimes used to treat or prevent heart attacks, strokes, and chest pain
(angina).
 Aspirin should be used for cardiovascular conditions only under the
supervision of a doctor.
Dosage/Direction for Use
 Take each dose of aspirin with a full glass of water unless patient is fluid
restricted.
 Aspirin maintenance should be initiated once hypertension is controlled.
Before taking this medicine
 Do not give this medicine to a child or teenager with a fever, flu symptoms,
or chickenpox. Aspirin can cause Reye's syndrome, a serious and sometimes
fatal condition in children.
You should not use aspirin if you are allergic to it, or if you have:
 a recent history of stomach or intestinal bleeding;
 a bleeding disorder such as hemophilia; or
 if you have ever had an asthma attack or severe allergic reaction after taking
aspirin or an NSAID (non-steroidal anti-inflammatory drug) such as Advil,
Motrin, Aleve, Orudis, Indocin, Iodine, Voltairean, Toradol, Mobic, Relafen,
Feldene, and others.
To make sure this medicine is safe for you, tell your doctor if you have:
 asthma or seasonal allergies;
 stomach ulcers;
 liver disease;
 kidney disease;
 a bleeding or blood clotting disorder;
 gout; or
 heart disease, high blood pressure, or congestive heart failure.
How should I take aspirin?
 Take aspirin exactly as directed on the label, or as prescribed by your doctor.
Do not use in larger or smaller amounts or for longer than recommended.
 Always follow directions on the medicine label about giving aspirin to a
child.
 Take with food if aspirin upsets your stomach.
 You must chew the chewable tablet before you swallow it.
  Do not crush, chew, break, or open an enteric-coated or delayed/extended-
release pill. Swallow the pill whole.

Aspirin side effects

 Get emergency medical help if you have signs of an allergic reaction to
aspirin: hives; difficult breathing; swelling of your face, lips, tongue, or
throat.
Stop using this medicine and call your doctor at once if you have:
 ringing in your ears, confusion, hallucinations, rapid breathing, seizure
(convulsions);
 severe nausea, vomiting, or stomach pain;
 bloody or tarry stools, coughing up blood or vomit that looks like coffee
grounds;
 fever lasting longer than 3 days; or
 swelling, or pain lasting longer than 10 days.
 Common aspirin side effects may include:
 upset stomach, heartburn;
 drowsiness; or
 mild headache.
This vitamin can be taken in the morning after breakfast.

What is sodium ascorbate zinc used for?

This nutritional supplement contains vitamin C and zinc. Vitamin C and zinc
together help the body's natural defense against damaging free radicals (antioxidant
effect) and help boost immune function.

Side Effects
 Diarrhea
 Nausea
 Vomiting
 abdominal cramps/pain
 heartburn may occur.
If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

 If your doctor has directed you to use this medication, remember that your
doctor has judged that the benefit to you is greater than the risk of side
effects. Many people using this medication do not have serious side effects.
 Tell your doctor right away if any of these rare but very serious side effects
occur: painful urination, pink/bloody urine.
 A very serious allergic reaction to this drug is rare. However, seek
immediate medical attention if you notice any symptoms of a serious
allergic reaction, including: rash, itching/swelling (especially of the
face/tongue/throat), severe dizziness, trouble breathing.
 This is not a complete list of possible side effects. If you notice other effects
not listed above, contact your doctor or pharmacist.