Quiz 10 Modern Techniques

This method can be applied to model systems to DNA microarrays are used in clinical diagnostic
measure responses to experimental stimuli and to tests for Pre-natal diagnosis
gain insight into potential changes in protein level
a) True
and function
b) False.
a) SKY
aCGH evaluates all except:
b) ARMS
c) PCR. a) developmental
d) aCGH b) cancer diagnosis.
c) malformations
SKY technique was introduced in
d) prenatal diagnosis
a) 1998
All are wrong about the sequences of a DNA
b) 1997
segment have many uses except:
c) 1999
d) 1996. a) Enhances telepathy
b) To split it into half
CGH is visualized using epifluorescence telescope
c) Can be mutated
a) True d) Finding genes.
b) False.
The individual's DNA is labeled with ___ dye and
FISH was introduced in the control - or normal - DNA is labeled with
_____dye.
a) 1986.
b) 1998 a) Red, Green
c) 1999 b) Red, Blue
d) 1997 c) Green, Red.
d) Blue, Red
Real-time PCR simply refers to amplification of
DNA that is not monitored while the amplification is Variable molecular cytogenetic techniques have
occurring. been recognized as alternatives to chromosomal
banding as they enhance thorough interpretation of
a) True
numerical and complex chromosome aberrations
b) False.
by bridging the gap between conventional banding
All are correct about molecular cytogenetic analysis and molecular genetic studies.
techniques except:
a) True.
a) CGH b) False
b) ACE.
Southern Blot is a technique named after
c) SKY
d) FISH a) Thomas Southern
b) David Southern
DNA microarrays are used in clinical diagnostic to
c) Edward Southern.
determine which drugs might be best prescribed for
d) Knock E Southern
particular individuals
a) True.
b) False
 Quiz 10 Modern Techniques
Mass spectrometer should always perform the
following processes except:
a) Process the signals from the detector that
are transmitted to the computer and control
the instrument using feedback
b) Separate these ions according to their
mass-to-charge ratio in the mass analyzer
c) Detect the ions emerging from the last
analyzer and measure their abundance with
the detector that converts the ions into
electrical signals
d) Produce Iron from the sample in the
ionization source.
CGH is more efficient in the analysis of pneumonia.
a) True
b) False.
Traditional techniques are widely used as adjuncts
to traditional cytogenetics for identifying
chromosomal alterations.
a) True
b) False.
CGH is faster than FISH
a) True.
b) False
DNA probes and Chromosomal sequences are the
2 basic elements of FISH.
a) True
b) False.
A major difference between both techniques is;
FISH involves the use of labeled probes while
PRINS involves the use of unlabeled probes.
a) True.
b) False
FISH was introduced by
a) Pinkel.
b) Prinkel
c) Panickel
d) Pinckel