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Nurse Education Today 84 (2020) 104250

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Nurse Education Today


journal homepage: www.elsevier.com/locate/nedt

Medication error encouragement training: A quasi-experimental study T


Kyoungja Kim , Insook Lee

Department of Nursing, Hannam University, Daejeon, South Korea

ARTICLE INFO ABSTRACT

Keywords: Background: Medication errors are the most common clinical errors in healthcare practice and can lead to
Medication errors serious consequences. Medication error encouragement training (MEET) brings students face-to-face with po-
Safety tential errors in the medication process, in a safe environment where they are encouraged to understand both the
Education error and the context in which it occurred.
Nursing students
Objectives: The study aimed to examine the effects of a MEET intervention on medication safety confidence
among nursing undergraduates.
Design: This was a quasi-experimental study with a nonequivalent control group design.
Participants: Our sample was recruited from the nursing education department of a university, with 47 parti-
cipants randomly assigned to the experimental group, and 50 to the control group.
Methods: Both groups received theoretical training, followed by applied training. The experimental group re-
ceived the MEET intervention developed specifically for this study, while the control group received traditional
error avoidance training. Participants' medication administration confidence was measured pre- and post-in-
tervention.
Results: Following training, the experimental group's confidence was significantly higher than that of the control
group. With regard to individual medication administration procedures, the experimental groups' medication
safety confidence increased significantly after training compared to the control group in patient identification,
drug information confirmation, and drug preparation.
Conclusions: Introducing MEET into nursing curricula could reduce medication errors and related complications
in healthcare institutions. Further studies are needed to investigate the long-term effects of MEET interventions,
as well as the generalizability of our findings.

1. Introduction consumer” (National Coordinating Council for Medication Error


Reporting and Prevention, 2018). It can occur at any stage of the
Medication administration is one of the most frequently performed medication process—prescription, verification, preparation, delivery,
nursing tasks, accounting for about 40% of all nursing work (Hewitt or administration. Given the significant number of work hours nurses
et al., 2015), and is a multidisciplinary, multistep process that requires spend on medication administration, it is important to consider an Is-
several types of professional knowledge, such as the pharmacological raeli study's finding that 36% of nurses make medication errors (Natan
characteristics of drugs. Medication administration in clinical practice et al., 2017). Most medication errors are preventable (Hewitt et al.,
is becoming more complex as a result of medication route and medical 2015); therefore, more effective medication process management is
device diversification and increasing severity of patients' conditions. needed.
For this reason, a large percentage of medical accidents are related to Training nurses to perform correct and accurate medication ad-
medication errors (Natan et al., 2017). According to Australian statis- ministration is a crucial task. Although medication education is in-
tics, about 230,000 cases of medication-related accidents occurred from cluded in most nursing curricula, current approaches fail to adequately
2011 to 2012, which translates to about AUS $1.2 billion in hospital equip nurses with the required clinical competency levels (Page and
stay costs (Roughead et al., 2013). McKinney, 2007; Vaismoradi et al., 2014). Cleary-Holdforth and Leufer
Medication error refers to “any preventable event that may cause or (2013) pointed out that medication practice aspects, such as pharma-
lead to inappropriate medication use or patient harm while the medi- cology, pharmacokinetics, pharmacokinetic calculation, and medica-
cation is in the control of the healthcare professional, patient, or tion practice are taught independent of each other. The authors argued


Corresponding author at: Hannam University, Department of Nursing, 70 Hannam-ro, Daedeok-gu, Daejeon 34430, South Korea.
E-mail address: asteria43@hnu.kr (K. Kim).

https://doi.org/10.1016/j.nedt.2019.104250
Received 28 March 2019; Received in revised form 17 August 2019; Accepted 16 October 2019
0260-6917/ © 2019 Elsevier Ltd. All rights reserved.
K. Kim and I. Lee Nurse Education Today 84 (2020) 104250

that these knowledge areas should be integrated to equip students with Table 1
contextually sound medication safety competency. Research design.
Measurements
2. Background
Pre-intervention Intervention Post-intervention
Existing approaches to medication education, such as the “five
Intervention group E1 X E2
rights” and “seven rights” models, focus on adherence to the correct Control group C1 X′ C2
principles when engaging in the medication process. However, these
approaches fail to equip students with the practical medication com- Key: X: MEET; X′: General medication safety education, E, C: Confidence in
petence required in a clinical setting (Vaismoradi et al., 2014). More- medication safety performance.
over, the narrow focus of this approach to applying the “right” princi-
ples, fails to foster the skills needed to cope with errors when they do administration confidence before and after a medication error en-
occur in a clinical setting (DaRosa and Pugh, 2012). Error training is couragement training intervention. We compared pre- and post-inter-
one attempt to overcome this limitation. vention confidence levels (Table 1) between an experimental group that
DaRosa and Pugh (2012) classified error training into three types: received MEET, and a control group that underwent an existing edu-
error encouragement training, error guidance training, and error cation program utilizing error avoidance training. Both groups con-
avoidance training. The “right principle” approach described previously sisted of nursing undergraduates.
can be classified as error avoidance training. In this type of training,
errors are understood to be the result of a performance failure, leaving 3.2. Participants
little room for students to learn from their errors. In contrast, error
encouragement training encourages students to make errors in a safe Study participants were undergraduate students who had completed
and contained environment (D'Angelo et al., 2015; DaRosa and Pugh, training on the standard oral medication administration technique
2012). This type of training enables students to observe, experience, suggested by the Korean Accreditation Board of Nursing (KABONE,
and reflect on the error, its causes and consequences, and strategies for 2014). Convenience sampling was used to recruit prospective graduates
avoiding it in future (DaRosa and Pugh, 2012). When students under- at a university nursing department located in a large city in South
stand the context in which an error occurs, they are better equipped to Korea. This approach was intended to control for the exogenous vari-
apply their theoretical knowledge to address it and prevent future oc- ables that may affect the outcome and dependent variable of this study,
currences (Gardner and Rich, 2014; Gardner et al., 2015). Error en- namely the differences in completed units of the nursing major; dif-
couragement training may be particularly useful in aspects of medica- ferences in individual accomplishment regarding medication nursing;
tion practice with high error rates, and where errors may bear critical and differences in nursing curricula across schools, such as extra-
costs (DaRosa and Pugh, 2012; Keith and Frese, 2008; King et al., 2013; curricular activities. The required sample size was computed to be 102
Gardner and Rich, 2014; Gardner et al., 2015). using G*Power software 3.1.9.4 (Faul et al., 2007), with α = 0.05,
One of the greatest challenges nursing undergraduates experience power 0.8, and effect size 0.15. Students who provided consent to
after graduation is the practical application of what they have learned participate were paired based on mean GPA in the preceding semester.
(Becker et al., 2006; Holter, 2008). Despite prolonged hours of medi- The resulting sample contained 97 participants, who were randomly
cation administration education, they fear medication errors in parti- assigned to an experimental group (47) and control group (50) using a
cular and report low confidence for performing medication techniques random number table. Fig. 1 presents a CONSORT flowchart of the
they have been repeatedly trained on (Vaismoradi et al., 2014). When sampling process (Consolidated Standards of Reporting Trials, 2010).
faced with medication administration in the clinical setting, students Data were collected from April 2016 to June 2017.
with low medication confidence become easily distressed by anxiety
and fear of making a mistake, which undermines their medication 3.3. Procedures
competency and leads to medication errors (Sulosaari et al., 2011).
Confidence in their skills, on the other hand, has been pinpointed as a The MEET program that was developed for and applied in this study
factor that improves the outcome of nursing behaviors, with confident comprised 4 h of applied training using a clinical scenario that en-
nurses demonstrating high medication administration competency compassed the entire medication administration process, from pre-
(Andrew et al., 2009; Sulosaari et al., 2011). scribing to recording, in which oral medication administration errors
Against this backdrop, our study aimed to investigate the effects of could easily occur. In this type of training, error is a component of the
error encouragement training on medication confidence among nursing learning process itself, encouraging students to engage in reflective
graduates who had previously received error avoidance training. Oral learning regarding the context in which the error occurs. This approach
medication administration was chosen as the training topic. This is a provides students with a platform for learning about the causes and
relatively simple administration route in which it is unlikely that par- presentation of the error, as well as the knowledge and skills necessary
ticipants' skills and level of knowledge would interfere; however, oral to respond to it (Gardner and Rich, 2014).
medication error accidents occur regularly (Keers et al., 2013). We The MEET scenario was developed by the research team in con-
assessed the effects of medication error encouragement training (MEET) sideration of nursing graduates' knowledge levels, and involved a si-
using clinical scenarios for oral medication administration procedures tuation requiring oral medication administration for adult patients with
vulnerable to error. The objective of this study was to compare the safe major medical-surgical conditions, such as congestive heart failure,
medication administration confidence of a control group that received pneumonia, general surgery, and orthopedic surgery. It was designed to
general medication safety education, with an experimental group that induce errors at each step of the medication process, including patient
received MEET, before and after intervention. information confirmation, drug information confirmation, interpreta-
tion and communication of drug prescription, drug preparation, ad-
3. Methods ministration, recording, and post-administration patient monitoring.
The medication errors used in the scenario were designed based on the
3.1. Research design results of a previous study and actual reports about medication-related
errors in a tertiary university hospital in South Korea. Each scenario
We conducted a quasi-experimental non-equivalent control group contained two or more error-prone situations for each stage of medi-
study aimed at identifying the differences in safe medication cation administration such that students could experience a variety of

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K. Kim and I. Lee Nurse Education Today 84 (2020) 104250

Fig. 1. CONSORT flowchart.

medication errors. For example, the interpretation and communication difficulty as that used for the experimental group. Expert validity of this
of the drug prescription stage included errors such as dosage, admin- traditional education approach was established by one nursing pro-
istration route, whether the medication was appropriate, potential al- fessor and two nurses, each with more than ten years of clinical ex-
lergic components, drug interactions, and medications with similar- perience.
sounding names. The communication stage included noise (e.g., diffi- Prior to receiving the training, both groups were given a two-hour
culty with phone communication); the environmental stage included lecture on medication principles and safety. The lecture presented
time pressure and the information seeking process; the drug adminis- students with the ten medication safety practice guidelines developed
tration stage included medication settings, such as unusual dosage, by the Institute for Safe Medication Practices (ISMP, 2011), the stan-
route, or time; and error-prone situations included patients' individual dards prescribed by the Korean Institute for Healthcare Accreditation
situation (e.g., pre-administration assessments, changes in patient's (KOIHA, 2014), and the medication-related safety requirements for
state, patient special demands). Expert validity of this MEET scenario accreditation by Joint Commission International (JCI, 2014).
was established by one nursing professor and two nurses, each with
more than ten years' clinical experience. We chose oral medication 3.4. Measures
administration as the scenario topic because it was relatively unin-
fluenced by individual skill differences, which allowed us to assess the Confidence in medication safety performance was measured before
effects of the intervention alone. and after the intervention for both groups. Subjective confidence in the
During the applied training component of the program, two to four medication safety procedure per the ISMP (2011), KOIHA (2014), and
students practiced oral medication administration according to the JCI (2014) standards were measured using a tool we developed based
MEET scenario for 15 to 20 min. Students were exposed to various on the items suggested by the ISMP (2011; prescribing and transcribing,
medication errors during their practice, which was followed by a confirming the appropriateness of the prescription, preparing, admin-
twenty-minute debriefing by the instructor to facilitate internalizing istering, recording, and monitoring); the medication administration
their experiences. checklist endorsed by the KOIHA (2014) and JCI (2014); and the oral
The control group received the traditional medication safety edu- medication administration principles endorsed by the KABONE (2014).
cation, which takes the “right principle” approach discussed above. The Expert validity of the items was established by three nursing experts
program consists of 4 h of applied training using a scenario designed with more than 15 years of clinical experience each and one nursing
not to induce error. This scenario was designed at the same level of professor. The tool was tested in a pilot study on four nurses with two or

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K. Kim and I. Lee Nurse Education Today 84 (2020) 104250

more years of clinical experience each. The final tool consisted of 36 4.2. Pre- and post-treatment differences in medication safety confidence
items in eight subcategories, with five items for patient information between the intervention and control groups
confirmation, six items for drug information confirmation, two items
for communication of prescription and drug information, eight items Table 3 shows the pre- and post-treatment differences in medication
for preparation, ten items for administration, one item for recording, safety confidence between the experimental and control groups. After
two items for patient monitoring, and two items for medication safety the intervention, the experimental group showed a significant increase
management. Each item was scored on a 100-point scale (0 = I am not in confidence in oral medication safety compared to the control group
confident at all to 100 = I am very confident). The reliability of the tool (t = 3.52, p = .001). Among the domains of oral medication adminis-
was established with Cronbach's α of 0.81. tration, the experimental group showed significant improvement in
confidence regarding patient information confirmation, drug informa-
3.5. Ethical considerations tion confirmation, and drug preparation.

The study received ethical clearance from the institutional review 5. Discussion
board at H University (clearance number 15-05-01-0128). The re-
searchers provided participants with information on the purpose and The MEET intervention was developed to enhance nursing under-
procedure of the study. Participants were informed that they would not graduates' confidence in safe medication administration based on MEET
be disadvantaged in any way if they chose not to participate in the error encouragement training, which treats errors that may occur in
study, and that their participation was irrelevant to the curriculum of actual practice as learning components and allows students to focus on
the nursing department. Students who provided informed consent were both their actions and errors during training, facilitating reflective ex-
enrolled in the study. amination of the cause and process of their errors. Errors in the medical
field can have critical outcomes, so they need to be approached from
both an avoidance and a management perspective. Errors increase an-
3.6. Data analysis xiety and fear of failure in graduate nurses, which in turn diminishes
their performance confidence and hinders a successful transition (Della
Data were analyzed using IBM SPSS Statistics (version 22). Ratta, 2016). A benefit of error encouragement training is that students
Participants' general characteristics, learning-related characteristics, can advance their performance capacity and accurately understand
and major study variables were analyzed using frequency, percentage, errors by actively experiencing errors in a safe environment (Gardner
mean, and standard deviation functions. The homogeneity of general et al., 2015). In addition, error management training is useful for novice
characteristics and learning-related characteristics between the two learners in that it enhances their performance as they safely experience
groups were verified with the χ2 test, independent t-test, and Fisher's errors (Dyre et al., 2017).
exact test. Differences in performance confidence before and after the Because of these benefits, error training has been actively used in
intervention in both groups were analyzed with the independent t-test. medical education (Gardner et al., 2015; Gully et al., 2002; Eva, 2009).
Dyre et al. (2017) applied error encouragement training in simulation-
4. Results based ultrasound training for medical students and reported that it
improved their diagnostic accuracy performance with real patients.
4.1. Pre-treatment homogeneity of general characteristics and dependent Gardner et al. (2015) reported that incorporating error encouragement
variables between the intervention and control groups training into central venous catheterization simulation was effective in
terms of interns' skill retention, which the investigators attributed to
The mean age was 23.7 ± 1.38 years for the experimental group students' ability to acquire an in-depth understanding of the full pro-
and 22.78 ± 1.13 years for the control group. The majority of parti- cess. This understanding translates into long-term learning effects, as
cipants were women in both the experimental group (83%) and control the instructor actively encourages students to make errors and then
group (92%). The mean GPA was 3.43 ± 0.34 and 3.54 ± 0.39 for the extensively discusses these errors. To apply these benefits to medication
experimental and control groups, respectively. There were no sig- safety, we designed our training program to allow students to experi-
nificant differences in these general characteristics between the two ence making errors in a safe environment. We chose oral medication
groups. There were also no significant differences in pre-treatment administration as the scenario topic, since it is not greatly influenced by
medication safety confidence between the two groups, as shown in individual skill differences and allowed us to control for individual skill
Table 2. differences and exclusively assess the effects of the error

Table 2
Differences in the general characteristics and medication safety confidence (pre-treatment measurement) between the intervention and control group.
Variables M ± SD or N(%) t or χ2 p

Intervention group (47) Control group (50)

General characteristics Age 23.71 ± 1.38 22.78 ± 1.13 1.52 .131


Gender Female 39(83.0) 46(92.0) 1.81 .224
Male 8(17.0) 4(8.0)
GPA (max 4.5) 3.43 ± 0.34 3.54 ± 0.39 1.47 .144
Performance confidence of oral medication Patient information identification 70.32 ± 12.28 71.84 ± 15.04 0.54 .588
safety Medication information identification 62.76 ± 12.31 64.64 ± 11.42 0.78 .438
Communication about medication prescription and medication 66.53 ± 17.65 67.61 ± 19.12 0.29 .774
information
Medication preparation 87.95 ± 8.26 88.42 ± 9.73 0.25 .801
Medication administration 89.46 ± 8.36 89.71 ± 9.64 0.14 .890
Recording 87.14 ± 11.64 85.40 ± 16.18 0.61 .545
Monitoring of patient 76.40 ± 12.37 77.15 ± 14.64 0.27 .788
Medication safety management 66.69 ± 17.28 67.05 ± 18.65 0.99 .922
Total 78.60 ± 6.74 79.23 ± 8.75 0.39 .697

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K. Kim and I. Lee Nurse Education Today 84 (2020) 104250

Table 3
Difference in pre-post medication safety confidence between intervention and control group.
Variables M ± SD △post-pre t
(p)
Intervention group Control group

Pre Post Pre Post

Patient information identification 70.32 ± 12.28 85.20 ± 9.43 71.84 ± 15.04 76.92 ± 12.51 Exp 13.17 ± 14.33 2.51
Con 6.60 ± 11.18 (.014)
Medication information identification 62.76 ± 12.31 83.79 ± 9.37 64.64 ± 11.42 77.00 ± 10.18 Exp 19.14 ± 9.66 2.36
Con 14.23 ± 10.85 (.021)
Communication about medication prescription and medication 66.53 ± 17.65 86.17 ± 11.75 67.61 ± 19.12 81.01 ± 13.04 Exp 18.56 ± 18.79 1.10
information Con 14.47 ± 17.54 (.272)
Medication preparation 87.95 ± 8.26 95.00 ± 6.76 88.42 ± 9.73 90.76 ± 8.92 Exp 6.58 ± 8.29 2.43
Con 2.80 ± 6.91 (.017)
Medication administration 89.46 ± 8.36 95.27 ± 7.74 89.71 ± 9.64 94.09 ± 7.25 Exp 5.56 ± 6.34 0.67
Con 4.63 ± 7.26 (.503)
Recording 87.14 ± 11.64 93.08 ± 10.73 85.40 ± 16.18 91.80 ± 9.85 Exp 7.68 ± 13.18 1.18
Con 4.65 ± 12.06 (.243)
Monitoring of patient 76.40 ± 12.37 87.80 ± 12.01 77.15 ± 14.64 82.29 ± 12.86 Exp 10.65 ± 14.94 1.68
Con 5.89 ± 12.80 (.097)
Medication safety management 66.69 ± 17.28 85.26 ± 15.90 67.05 ± 18.65 77.89 ± 13.75 Exp 18.21 ± 20.43 1.86
Con 11.20 ± 16.25 (.066)
Total 78.60 ± 6.74 90.35 ± 35 79.23 ± 8.75 85.73 ± 6.60 Exp 11.11 ± 5.73 3.52
Con 7.12 ± 5.41 (.001)

encouragement training. to better navigate these obstacles in practice. By experiencing errors


During the MEET program, many students were flustered when they that frequently occur in this process, students learned that systemic
made a mistake, feeling they had failed the training. As noted by factors and individual factors both contribute to errors.
DaRosa and Pugh (2012), this type of response seemingly results from Medication administration is an appropriate topic for error en-
medical education's traditional framing of errors as indicative of failure couragement training in that it is a common and frequent task per-
and something to be avoided. When students fear and avoid errors, the formed by nurses, requiring integrated thinking and continuity of
benefits of error encouragement training are thwarted. Fear and practice, and is also a task vulnerable to error. In this context, the
avoidance may also hinder students' medication administration prac- current study has important theoretical implications in that it verifies
tice. Therefore, instructors must actively discuss this with students and the effects of error encouragement training on medication safety. The
encourage them to make errors in an accepting environment when study also has practical implications in proposing the MEET program as
administering error encouragement training. a new training program that provides an opportunity for nursing
The MEET program was effective in boosting medication safety graduates to integrate segmented knowledge and use error as a learning
confidence among nursing graduates. The resultant decrease in anxiety component. The MEET program has practical benefits; it is easy to
should facilitate safer and more effective medication administration administer and can be adequately incorporated into the existing nursing
(Kim et al., 2012; McMullan et al., 2010; Vaismoradi et al., 2014). The curricula.
MEET program also lowered students' anxiety about errors by actually However, the following study limitations should be considered.
encouraging them to make errors. In addition to its educational effect First, the developed MEET program had limited content on medication
pertaining to error itself, error management training also positively errors from a nursing perspective. There were not enough studies for us
influences the negative psychological consequences of students' errors to determine the type of errors that would be beneficial as learning
(Frese and Keith, 2015). King et al. (2013) reported that applying error materials when we were developing the scenario and setting errors for
encouragement training in medical team training led to better emo- each medication step. In Korea, healthcare institutions are still reluctant
tional control and increased foresight for managing the situation. Psy- to disclose any medication errors in their institutions, so there is a
chological preparation for a task influences task performance; error shortage of accurate statistics regarding medication errors. Therefore,
training enhances task performance by strengthening students' emo- this study designed medication error scenarios based on a review of
tional control and metacognition (Keith and Frese, 2005). international literature on medication errors and a survey of medication
Another educational benefit of error management training involves errors in a large (over 1000 beds) tertiary hospital in Korea over a one-
error detection training during an organizational task process. Frese year period. In the future, basic learning content should be more di-
and Keith (2015) reported that error encouragement training was ef- versified by investigating medication errors that occur frequently in the
fective in detecting error related processes. This was confirmed in our clinical setting.
study as well, where confidence in patient information confirmation, Second, educators must consider the following when applying error
drug information confirmation, and drug preparation steps were sig- encouragement training. First, learners must be prepared with the pre-
nificantly improved. This is important because these three aspects of requisites, such as basic knowledge about a task, to learn through error
medication administration are more easily influenced by systemic fac- management training (Eva, 2009; Dyre et al., 2017). Second, learners
tors. The drug information confirmation stage, in particular, requires must understand that errors during the training do not represent failure
that individuals have the professional knowledge needed to confirm (Metcalfe, 2017; Dyre et al., 2017). Third, educators must include well-
medication appropriateness in the context of the patient's medical designed situations (Frese and Keith, 2015) and provide well-structured
status, review its interactions with previously prescribed drugs, effec- debriefing such that students can reflect on their actions and errors
tively communicate their conclusions to physicians and pharmacists, (Metcalfe, 2017; Dyre et al., 2017). During MEET implementation,
and engage in detailed communication with physicians (regarding many participants were distressed when induced errors occurred,
prescriptions) and pharmacists (regarding preparation). The MEET in- feeling that their errors meant that they failed the training. These
tervention exposed students to the process in a way that revealed the prospective nursing graduates had been educated with a focus on error
systemic contributors to medication errors, which should enable them avoidance over the previous four years, so they were disturbed and

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K. Kim and I. Lee Nurse Education Today 84 (2020) 104250

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