BRAND NAME GENERIC Prescribed and Mechanism

NAME CLASSIFICATION Recommended dosage, Of

frequency, route of Action Indication Contraindication Adverse Reaction Nursing Responsibilities
administration

Brand name: Methergine ➣ Prevention and Directly stimulates ➣ Prevention and ● Hypersensitivity to drug CNS: dizziness, headache, Administration
treatment of postpartum vascular smoothmuscle treatment of postpartum hallucination,seizures,
Generic name: hemorrhage contractions in uterus and hemorrhage ● Hypertension CVA (with I.V. use) ● Be aware that drug isn’t
routinely
methylergonovine Adults: 0.2 mg I.M.; cervix and decreases ● Toxemia CV: hypertension,
maleate repeat q 2 to 4 bleeding after hypotension, transient given I.V. because of risk
● Pregnancy (except of severe
chest pain, palpitations,
Pharmacologic class: hours as needed to a total delivery during third stage
thrombophlebitis
Ergot alkaloid of five doses. hypertension and
of labor) cerebrovascular accident
EENT: tinnitus, nasal
Therapeutic class: In emergencies, 0.2 mg congestion (CVA). Monitor blood
Oxytocic Precautions
I.V. over 1 minute. After pressure
initial I.M. or I.V. dose, 0.2 Use cautiously in: GI: nausea, vomiting,
Pregnancy risk category C diarrhea and uterine contractions
mg P.O. q 6 to 8 hours for ● severe hepatic or renal during
2 to 7 days; disease, vascular disease, GU: hematuria
administration.
jaundice, sepsis
decrease dosage if Musculoskeletal: leg
cramping occurs. cramps ● If I.V. use is necessary,
● patients in second stage
give dose
of labor.
Respiratory: dyspnea
over 1 minute. Dose may
Skin: diaphoresis, rash, be diluted
allergic reactions
in 5 ml of 0.9% sodium
Other: foul taste chloride

injection.

● Be aware that
prolonged therapy

should be avoided
because of ergotism

risk.
Patient monitoring

2Know that if used during

third

stage of labor, drug

increases risk of

hemorrhage and infection.

● When giving I.V., closely

monitor

blood pressure, pulse,

uterine contractions, and
bleeding.

● Monitor patient for

adverse effects.

Patient teaching

● Inform patient and

family of reason

for using drug, and

provide reassurance.

● Tell patient drug may

cause nausea,

vomiting, dizziness,
increased blood

pressure, headache,
ringing in ears, chest pain,
or shortness of breath.

Advise her to report

severe or troublesome
symptoms.

● As appropriate, review
all other significant and
life-threatening adverse

reactions and interactions,

especially

those related to the drugs

and tests

mentioned above.