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Sports Medicine (2021) 51:653–660

https://doi.org/10.1007/s40279-020-01404-7

REVIEW ARTICLE

Return to Sport and Reinjury Rates in Elite Female Athletes After


Anterior Cruciate Ligament Rupture
Kate E. Webster1 

Accepted: 28 November 2020 / Published online: 7 January 2021


© The Author(s), under exclusive licence to Springer Nature Switzerland AG part of Springer Nature 2021

Abstract
While there has been significant interest in the documentation of return to sport outcomes following anterior cruciate ligament
(ACL) injury, the elite level female athlete has not been a focus of this research. This is despite women being at increased
risk for ACL injury and considerable global growth in women participating in sport. Therefore, the focus of this review was
to examine the available literature regarding return to sport outcomes in elite level women with an ACL injury. The topics
of discussion focus on return to sport rates, timing and determinants of return to sport, longevity of play, return to sport
performance, and further ACL injury. Knee health in the longer term is also briefly discussed along with the limitations of
the existent literature.

Key Points  injury occurs in 1 out of every 29 female athletes compared


to 1 out of every 50 male athletes [1]. When level of sport is
Most elite female athletes return to the same preinjury considered, ACL injuries occur at approximately twice the
sport participation after anterior cruciate ligament (ACL) rate in both amateur and elite females compared to males
injury. [1]. Therefore, female athletes are particularly susceptible
to this devastating injury at all levels of sport participation.
Data regarding performance on return to play after ACL
A goal for most athletes, especially elite level athletes,
injury are severely lacking in elite female athletes.
who sustain an ACL injury is to be able to make a timely
The occurrence of a further ACL injury appears to be return to their preinjury level of sport participation [2]. As
relatively common and is estimated to occur in one in such, there has been much interest in documenting sport
four elite female athletes. related outcomes such as return to sport rates, the ability to
achieve preinjury levels of performance as well as reinjury
occurrence. However, the datasets that have been used to
determine return to sport outcomes at the elite level pre-
1 Introduction dominately consist of male athletes. This was highlighted
by Mohtadi and Chan [3] in a review of return to sport per-
It is well established that female athletes are at greater risk formance, where it was noted that most of the available data
of sustaining an anterior cruciate ligament (ACL) injury than were only for elite male athletes. Therefore, data for elite
male athletes. Across all sports it has been shown that this female athletes tend to be diluted or overlooked within the
literature on return to sport outcomes following ACL injury.
This is despite women being at increased risk for this dev-
Electronic supplementary material  The online version of this astating injury along with  a considerable global growth in
article (https​://doi.org/10.1007/s4027​9-020-01404​-7) contains
women’s sport at all levels of participation. Therefore, the
supplementary material, which is available to authorized users.
purpose of this review was to evaluate return to sport out-
* Kate E. Webster comes in elite level female athletes who have sustained an
k.webster@latrobe.edu.au ACL injury. Elite will be defined as professional sport par-
1 ticipation or participation at the highest competitive level
School of Allied Health, Human Services and Sport, La
Trobe University, Kingsbury Drive, Bundoora, VIC 3086, for the sport, including Division I of the National Collegiate
Australia Athletic Association (NCAA). Return to sport rates, timing

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K. E. Webster
654

and determinants of return to sport, longevity of play, return need to expand on these data and include a greater scope of
to sport performance and further injury will specifically be sports so that return rates can be determined for all sports in
the focus of discussion. which women participate.
The two studies that evaluated soccer at both senior elite
and collegiate levels showed similar return rates of 86% [7]
2 Return to Sport Rates and Timing and 85% [8]. Both also reported data on the time it took to
of Return be cleared for, or to return to, match play following ACL
reconstruction surgery. Women from the Swedish Women’s
Seven studies have reported return to sport rates in elite level First League [7] took an average of 253.6 days (approxi-
female athletes and these are detailed in Table 1. Three team mately 8 months) to return to match play and women in the
sports (soccer, basketball and handball) have been evaluated NCAA Division I South-eastern Conference were cleared
along with alpine skiing and the winter skiing and snow- for a return to unrestricted match play after an average of
boarding X-game events. Most athletes were treated with 6.1 months [8]. In basketball, the average time to return
surgical reconstruction. Return rates vary between sports to play in the Women’s National Basketball Association
and range from 54% in the earliest study on a subset of team (WNBA) after ACL reconstruction surgery was 11.8 months
handball players who underwent surgical treatment [4] to [9]. Therefore, whilst the timing of return to play can be
100% in international level alpine skiers [5]. Combining influenced by other external factors, it would appear that
return to sport data from Table 1 gives an overall return most elite level female athletes are able to return within the
rate of 82% (95% confidence interval 63–95%, Fig. 1) for first year following ACL reconstruction surgery.
elite female athletes. This is 1% lower than the 83% return
rate that was previously reported in a systematic review
and meta-analysis which contained 24 studies on return to 3 Determinants of Return to Sport
sport after ACL reconstruction in elite athletes [6]. There-
fore, despite there being extremely limited data on return to Two studies have examined some determinants of return
sport rates in elite level female athletes, from the data that to sport. Namdari et al. [9] reported that a return to play
are available, rates are similar to that reported in elite male in the WNBA was not influenced by age, the number of
athletes. This is different to the non-elite literature where preoperative seasons played, body mass index or player
return to sport rates have typically been lower, by around position when 14 players who had returned to match play
10%, in female compared to male athletes [2]. As the risk for were compared with 4 who did not. In collegiate soccer,
ACL injury varies between different sports, future work will Howard et al. [8] reported that return to play was also not

Table 1  Details of studies which have reported return to sport rates after ACL rupture in elite female athletes
Study Country or competition Sport No. of ACL treatment RTS definition RTS rate
athletes

Myklebust et al. [4] Norway (upper 3 divi- Handball 50 37 surgical Return to play at same All 31/50 (62%)
sions) 13 non operative level Surgical: 20/37 (54%)
Non-operative: 11/13
(85%)
Namdari et al. [9] USA (WNBA) Basketball 18 ACLR Return to play in 14/18 (78%)
WNBA
Walden et al. [7] Sweden (Women’s First Soccer 15 14 ACLR Match participation ACLR 12/14 (86%)
League) 1 non operative within 12 months
Erickson et al. [10] Winter X-games Skiers and 12 ACLR Return to X-games 9/12 (75%)
snow-
boarders
Haida et al. [5] France (international Alpine ski 81 Not stated Return to international 81/81 (100%)
level) level competition
Howard et al. [8] USA (NCAA Divi- Soccer 78 ACLR Return to collegiate 66/78 (85%)
sion I) competition
Tramer et al. [11] USA (WNBA) Basketball 59 ACLR Return to play in 41/59 (70%)
WNBA

ACLR anterior cruciate ligament reconstruction, RTS return to sport, WNBA Women’s National Basketball Association, NCAA​ National Colle-
giate Athletic Association
Elite Female Athlete Outcomes After ACL Injury 655

Fig. 1  Proportional meta-analysis (random effects model) showed an letes, to avoid double counting of athletes, only data from Tramer
overall return to sport rate of 82% (95% CI 63–95%) in elite female et  al. were included because their study time period (ACL injuries
athletes following ACL injury. Raw values from Table  1 were ana- sustained between 1997–2018) was greater and fully included the
lysed with StatsDirect software (V3.2; Altrincham, UK) to create this time period of Namdari et  al. (1998–2008). NCAA​ National Colle-
forest plot. For Myklebust et al. [4] all female athletes were included. giate Athletic Association, Div Division
As Namdari et al. [9] and Tramer et al. [11] both studied WNBA ath-

influenced by a variety of factors including player position, and usefulness of your own actions. Finally, goal setting
the use of a knee injury prevention program or a variety involved the ability to set clear and reasonable goals for
of ACL reconstruction surgical factors (i.e. graft source, both physical and psychological wellbeing and recovery.
type, or fixation device or concomitant procedures). Play- Although no causal relationship has been established
ers who were in their earlier years of college, and therefore between exhibiting such behaviours and actual return to
had more available seasons in which to make a return, play, it is reasonable to consider such behaviours as having
had significantly higher return rates. Being on a sporting an important modifying influence on return to play after
scholarship was also strongly associated with a return to ACL injury.
play in the female collegiate soccer players [8]. This may
be a surrogate measure which is indicative of greater ath-
letic skill, or motivation to perform well to maintain schol- 4 Performance on Return to Sport
arship funding, and similar findings in respect to higher and Career Longevity
return rates for athletes who are on scholarship have previ-
ously been reported in male American Football collegiate Data on performance after returning to sport following ACL
athletes [12]. injury in elite female athletes are severely lacking and has only
Successful rehabilitation is also a key factor in the been reported in three studies [5, 9, 11]. In the first of these,
return to sport pathway. To better understand what psy- 13 different performance measures were analysed for two full
chosocial features may be characteristic of resilience dur- seasons in 14 women who had returned to WNBA match play
ing rehabilitation, 13 athletes from the Swedish Women’s after ACL reconstruction surgery [9]. Only two of the perfor-
Elite Football League were interviewed after undergoing mance measures, shooting percentage and steals per 40 min of
ACL reconstruction for a first time ACL injury [13]. Three game time, were significantly decreased when pre to post sur-
core themes that helped players cope with the rehabilita- gery performance was compared. In addition, no performance
tion were identified and included communication, self- measure was significantly different between the players who
efficacy and goal getting. Communication entailed the had an ACL injury and those who did not. However, in a more
ability to have constructive interaction with significant recent study [11], in a larger group of 41 WNBA players who
others both within the sporting context, such as coaches had ACL reconstruction surgery, 10 out of 12 performance
and teammates, but also with family and friends outside of measures were significantly decreased compared with the
sport. Self-efficacy was having a belief in the importance year before injury. When compared to control athletes, those
K. E. Webster
656

with ACL reconstruction had significantly decreased perfor- 5 Further ACL Injury
mance regarding games played, games started, minutes played,
rebounds, assists and blocks per game in the first return to play A subsequent  ACL injury, whether it be a reinjury to the same
season; however, these differences resolved by the third year knee or a new injury to the contralateral ACL, is a devastat-
of play. In the NBA, athletes have also been shown to have a ing occurrence for an athlete who has resumed sport. There
decrease in performance for the season after returning from are some data from six studies on the rates of further ACL
injury but recover to preinjury levels in seasons 2 and 3 [14, injury in elite female athletes (Table 2). At the professional
15] and performance overall is not significantly different from level, subsequent ACL injuries have been documented in both
controls [16, 17]. basketball and soccer [9, 23, 27]. In the WNBA, graft rup-
In a study of 81 women alpine skiers, there were signifi- tures were found to occur in 7%-10% of women within the
cantly more podium finishes after ACL injury compared to first two–three playing seasons after reconstruction surgery
prior to injury (90 vs. 18 finishes respectively) [5]. Interna- [9, 11]. This rate increased to 16% when the entire career was
tional rankings also improved after surgery; however, it took considered, and the rate of all further ACL injuries was 21%
approximately 3.1 years after surgery for these best perfor- [23]. This is similar to the 26% further ACL injury rate that
mances to be achieved. Elite male skiers had similar findings. was seen in females participating in soccer as part of the Ger-
Interestingly, all athletes (male and female) who sustained an man National League [27].
ACL injury had higher preinjury performance rankings com- In a recent study, professional athletes from a variety of
pared to those who had never had an ACL injury, which may sports who were part of the Scientific Anterior Cruciate Liga-
indicate that more aggressive skiers are at greater risk for ACL ment Network International (SANTI) database and had under-
injury. ACL injured skiers also had longer career lengths. gone combined ACL and anterolateral ligament reconstruction
In studies of elite male athletes, it is usually acknowl- for a primary ACL injury were followed for a minimum of
edged that ACL injury is associated with a shorter career two years [28]. Most patients (86%) returned to their sport but
length. This has been reported across several different sports rates of further ACL injury in the female athletes were high
including soccer [18–20], basketball [21] and American at 36.4% (13.6% graft rupture and 22.7% contralateral ACL
Football [22]. However, in the WNBA Gordon et al. [23] injury) and significantly greater than the 13% rate reported in
reported that professional career length averaged 6.11 sea- elite male athletes from the same database.
sons for players with an ACL reconstruction compared to 5.7 Further ACL injury rates have also been shown to be
seasons for those without. However, it should be noted that high in female collegiate athletes. One in every 5 Division
ACL injured players whose career ended were not included I NCAA basketball players who reported a prior history
in this study. For women entering the WNBA Combine of an ACL tear suffered from a further ACL injury (to the
there was also no difference in career longevity for those same or a contralateral knee) during their college years [23].
who entered with a prior history of ACL surgery (mean Kamath et al. [29] stratified athletes who had sustained an
3.8 years) compared to those with no ACL surgery (mean ACL injury before entering college (precollegiate group;
3.4 years) [24]. In fact, those with a previous ACL injury PC) or during college years (intracollegiate group; IC) and
were 21% more likely to have an extended playing career found similarly high rates of repeat ACL reinjuries to the
length. Career length was also not affected by having ACL graft or opposite knee in both the female (23%) and male
surgery combined with meniscal surgery. Rugg et al. [25] (21%) athletes participating in a variety of sports. In addi-
also showed that NCAA Division I career length in athletes tion, of the 47 female athletes in the cohort, 16 (34%) had a
with a prior ACL injury was not different from those with- further knee operation of any type.
out across a variety of sports in both male and female ath- By combining available data from Table  2, the esti-
letes. Roos et al. [26] noted that none of the 19 elite national mated overall rate of further ACL injury is 26% for elite
female soccer players they surveyed at 7 years after ACL female athletes (Fig. 2). This is substantial and higher than
injury were still playing at the same level as before the the rates reported in men’s professional American Football
injury. This is perhaps not surprising, and unfortunately they (18%) [30] and soccer (16%) [31]. Similar rates have been
did not detail how many years the athletes had already been reported in men’s Australian Rules Football (30% second
playing at the elite level prior to injury or for how long they ACL injury rate) [32]. Caution must however be exercised
were able to return to play after injury to fully determine when interpreting injury rates in professional cohorts as the
whether the ACL injury had an impact on career longevity. total number of athletes is often small. However, from the
There are no other individual or team sports which have data that are available further ACL injury does appear to be
documented performance following ACL injury or career a significant issue that warrants reporting in all sports that
longevity in a cohort of elite female athletes from a defined women participate in so that injury reduction strategies can
sporting association or league. Future studies are clearly be advocated.
needed in this area.
Elite Female Athlete Outcomes After ACL Injury 657

Table 2  Details and results of studies that have reported further ACL injuries in elite female athletes
Study Country or compe- Sport Follow-up period Rate graft rupture Rate contralateral Rate all sub-
tition and RTS ACL injury sequent  ACL
injuries

Faude et al. [27] German National Soccer All RTS, unknown 5/19 (26.3%)
League time since ACL
injury
Namdari et al. [9] USA (WNBA) Basketball 78% returned RTS only: 1/14
for min 2 full (7.1%)
seasons Full cohort: 1/18
(5.6%)
Gordon et al. [23] USA (WNBA and Basketball All RTS, unknown WNBA 3/19 WNBA 1/19 WNBA 4/19
NCAA Divi- time since ACL (15.8%) (5.3%) (21.1%)
sion 1) injury NCAA: 4/34 NCAA: 3/34 NCAA: 7/34
(11.8%) (8.8%) (20.6%)
Kamath et al. [29] USA (NCAA Divi- Mixed All RTS, stratified PC: 3/20 (15.0%) PC: 3/20 (15.0%) PC: 6/20 (30.0%)
sion 1) ACL injuries that IC: 0/27 (0%) IC: 5/27 (18.5%) IC: 5/27 (18.5%)
occurred precol-
lege (PC) and
intracollege (IC)
Rosenstiel et al. France (SANTI Mixed (basketball, 85.7% returned to 3/22 (13.6%) 5/22 (22.7%) 8/22 (36.4%)
[28] database) handball, skiing, preinjury level,
soccer) min 2 years
follow-up
Tramer et al. [11] USA (WNBA) Basketball 70% returned for RTS only: 4/41
min 3 seasons (9.8%)
Full cohort: 4/59
(6.8%)

RTS return to sport, ACL anterior cruciate ligament, WNBA Women’s National Basketball Association, NCAA​ National Collegiate Athletics
Association, PC pre-collegiate, IC intra-collegiate, SANTI Scientific Anterior Cruciate Ligament Network International

Fig. 2  Proportional meta-
analysis (random effects
model) showing an overall
subsequent (graft rupture or
contralateral ACL injury) ACL
injury rate of 26% (95% CI
19–33%) in elite female ath-
letes. Raw values from Table 2
were analysed with StatsDirect
software to create this forest
plot. For Kamath et al. [29] the
precollegiate and intracollegiate
groups were combined. WNBA
Women’s National Basketball
Association, NCAA​National
Collegiate Athletic Association,
ACL anterior cruciate ligament

6 Long Term Knee Health soccer players (n = 49) who had been retired for a mini-
mum of 2 years and were aged between 30 and 50 under-
A recent study by Prien et al. [33] highlighted the potential went magnetic resonance imaging (MRI) and self-reported
for poor longer-term knee health in elite women athletes. symptoms of knee osteoarthritis. Results of the MRI anal-
In a cross-sectional study, former German elite female ysis indicated that 51% of the former players fulfilled the
K. E. Webster
658

criterion for knee osteoarthritis. Of the cohort, 17 athletes format was most appropriate as this allowed for numerous
had previously sustained combined ACL and meniscal areas of discussion. To ensure that all key studies were
injuries which had been surgically treated. This subgroup included, an electronic search of several databases (Med-
had the highest likelihood for both chondral and menis- line, SPORTDiscus, Embase and Cochrane) was under-
cal loss (odds ratios of 14.8 and 9.5 respectively when taken from which 2527 individual studies were screened
compared to players without injury). These findings are for relevance (see Supplementary Table S1 for details of
consistent with an earlier study in Sweden which showed terms used in the search).
that 51% of female soccer players fulfilled the criterion for
radiographic knee osteoarthritis 12 years after sustaining
an ACL injury [34]. Thirty-two percent of the cohort had 8 Conclusion
played top level soccer (first or second league in Sweden).
The combined data from both these studies are therefore This review has examined return to sport and further ACL
consistent with the notion that an ACL injury, particularly injury outcomes in elite female athletes who sustained an
when combined with meniscal injury, may greatly increase ACL injury. An overview of return to sport rates showed
the risk for the development of knee osteoarthritis [35]. that most elite female athletes (82%) can return to their
In young (20–26 years) elite male collegiate American same preinjury sport participation. Data regarding perfor-
Football players participating in the NFL Combine, 24% of mance on return to play are lacking, but the limited infor-
those with a prior ACL injury were shown to already have mation which is available indicates that performance is not
MRI evidence of osteoarthritic changes in the knee [36]. markedly impaired and career longevity is largely unaf-
This demonstrates that degenerative change can occur in fected after an ACL injury. However, the occurrence of a
the early years after injury. Unfortunately, there are no further ACL injury appears to be relatively common after
comparable female data, but as female athletes tend to returning to sport and is likely to occur in one in four elite
sustain ACL injuries at an earlier age than their male coun- female athletes who have had reconstruction surgery. It is
terparts it would be reasonable to hypothesise that they hoped that this review will promote further investigation
too may be susceptible to early osteoarthritic changes in of outcomes in elite female athletes who have sustained an
the knee. The impact of any such osteoarthritic changes ACL injury so that return to sport expectations can be met,
over time as well as the role of continued participation performance goals achieved, and reinjury risk reduced.
in high impact activity after an ACL injury are currently
unknown. Declarations 

Funding  No sources of funding were used to assist in the preparation


of this article.

7 Limitations and Future Work


Conflicts of interest  Kate Webster declares she has no conflicts of in-
terest relevant to the content of this review.
The scope of the current review was to explore a range of
return to sport outcomes, including further injury, in elite Availability of data and materials  All data are available within the
female athletes who had sustained an ACL injury. Ulti- manuscript.
mately, this review has highlighted that there are limited Ethics approval  Not applicable as a review paper.
data on this topic for this group of athletes. It is acknowl-
edged that it is a challenge to audit and include elite level Consent  Not applicable as a review paper.
athletes in research studies. However, sex specific informa-
tion is required to form a knowledge base so that outcomes
for women who have been injured through sport participa-
tion can be enhanced. Therefore, the assessment of such References
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