Professional Documents
Culture Documents
Omini Moses
08148255474, ominiriches@gmail.com
Department of Computer Science, Akanu Ibiam Federal Polytechnic
Unwana, Afikpo.
ABSTRACT
The study focused on Laboratory Database Management System (LDMS) which is an
evolving concept, with new features and functionality being added often. As laboratory
demands change and technological progress continues, the functions of a LDMS will likely
also change. Despite these changes, a LDMS tends to have a base set of functionality that
defines it. The problem encountered in the laboratory by staff couple with nurse’s laxity
(laziness) over their duties, the need arose to develop a software that will be able to solve the
problem. The problem caused by the use of manual method of keeping hospital laboratory
information and the use of manual method of keeping attendance scheme for patients can
only be solved by computerizing the hospital laboratory attendance scheme for user (lab
attendance) and computerizing the hospital laboratory information system. The input to the
system comes with various forms. Each of these forms has the function of collecting specific
data from the Med-Lab, doctors, staff and patients as the case may be. The first form is the
admission form details that enables the system to prompt the Doctors/Nurses to fill a
form that requires details from the patient concerning personal and health. The other forms
are for Lab Scientist, doctors, Nurses, bed management, patient in and out, etc are solely
intended for the administrative use for the staff. Here, the staff can add patients, doctors etc
that can include the services render by the hospital and change other things. After careful
observation and analysis of the existing system, the current system was a stone alone system
handle by the Laboratory Attendants or Technicians in the Hospital Laboratory, hence the use
of Php will be proposed for the design phase, while MySQl will be used as database at the
back-end. The choice of the programming language is relevant because of the interactive
tools and command, text area, and other project properties embedded in the language.
1.0 INTRODUCTION
The electronic data capture process of an LDMS or LIS can reduce time spent and cut errors
associated with the transcribing process (Khan et al., 2009). Maintenance of laboratory
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database systems took on added importance with the introduction of the meaningful
use program. The program is overseen by the Centers for Medicare & Medicaid Services and
consists of sets of criteria split into stage 1, stage 2 and stage 3. Participating healthcare
providers that successfully prove their electronic health record (EHR) systems or EHR
modules such as an LDMS satisfy program criteria are eligible for incentive payments. If an
LIS is tested and certified to meet meaningful use criteria or other health IT certification
standards, it is defined as an EHR module. The exponentially growing volume of data created
in laboratories, coupled with increased business demands and focus on profitability, have
pushed LDMS vendors to increase attention to how their LDMS handles electronic data
exchanges. Attention must be paid to how an instrument's input and output data is managed,
how remote sample collection data is imported and exported, and how mobile technology
integrates with the LDMS (Wood, 2007). The successful transfer of data files in spreadsheet
and other formats, as well as the import and export of data to MySQL, PostgreSQL, and other
databases is a pivotal aspect of the modern LDMS. In fact, the transition "from proprietary
databases to standardized database management systems such as MySQL" has arguably had
one of the biggest impacts on how data is managed and exchanged in laboratories (Wilkerson
et al., 2014). Labs using LDMS boost their level of professionalism and their ability to meet
customer demand in two ways:
LDMS helps labs produce accurate, reproducible results faster and more reliably
LDMS makes data from sequencing runs easier to store, track, and assess over time
and across experiments so that labs can evaluate and improve operational efficiency.
Prior to the problem encountered in the laboratory by staff couple with nurse’s laxity
(laziness) over their duties, the need arose to develop a software that will be able to solve the
problem. The problem caused by the use of manual method of keeping hospital laboratory
information and the use of manual method of keeping attendance scheme for patients can
only be solved by computerizing the hospital laboratory attendance scheme for user (lab
attendance) and computerizing the hospital laboratory information system. The problems
that this project is set to solve in the manual method of keeping outpatient information
are:
i. To provide end-to-end database management of samples, tests, and results for next-
generation genomics labs
ii. To accommodate different users with role-based interfaces to optimize lab efficiency
iii. To be easy for lab staff to configure and customize
iv. To offer out-of-the-box reports as well as the ability to create custom reports
v. To enable a lab to get up and running quickly on its preferred instrumentation.
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The Laboratory Database Management System (LDMS) is an evolving concept, with new
features and functionality being added often. As laboratory demands change and
technological progress continues, the functions of a LDMS will likely also change. Despite
these changes, a LDMS tends to have a base set of functionality that defines it. That
functionality can roughly be divided into five laboratory processing phases, with numerous
software functions falling under each:
(1) The reception and log in of a sample and its associated customer data,
(2) The assignment, scheduling, and tracking of the sample and the associated
analytical workload,
(3) The processing and quality control associated with the sample and the utilized
equipment and inventory,
(4) The storage of data associated with the sample analysis,
(5) The inspection, approval, and compilation of the sample data for reporting
and/or further analysis.
1.5 Scope of the Study
The scope of this study is centered on designing an Computerized Hospital Laboratory
Database Management System staff, laboratory attendance and for patients. In fact it involves
all parts of medical field in terms of record keepings for patient’s records and all other aspect
of field.
However, this project has been limited to GLMPD (General Laboratory Management/Patient
Department) which includes the following areas:
1. Recording of Laboratory Experiment/patient health record
2. Acceptance of Specimen/health report of Patient
3. Provisional of General Diagnosis for patient/Doctors prescription and treatment.
1.6 Definition of Terms
Computer: This is an electronic device that can accept data information of inputs,
process the data and it have the ability to store the data and also retrieves it for
future use.
Data: These are groups of non-random symbols such as words, figures, values
which represent event and things that have taken place.
Database: This is the collection of related files.
Hospital: This is a health facility where people who are ill or injured are
given medical treatments and care.
Information: this is a data that has been processed into a form which is
meaningful to the recipient and which is of perceived value in either current or
prospective decisions or action by the recipient.
Management: This is the process of getting activities completed efficiently with and
through other people.
Storage: This is a processing of storage data and information using storage media.
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manage samples and associated information. Labs using LDMS boost their level of
professionalism and their ability to meet customer demand in two ways:
LDMS helps labs produce accurate, reproducible results faster and more reliably
LDMS makes data from sequencing runs easier to store, track, and assess over time
and across experiments so that labs can evaluate and improve operational efficiency
(Skobelev, 2011).
i. Provide end-to-end information management of samples, tests, and results for next-
generation genomics labs
ii. Accommodate different users with role-based interfaces to optimize lab efficiency
iii. Be easy for lab staff to configure and customize
iv. Offer out-of-the-box reports as well as the ability to create custom reports
v. Enable a lab to get up and running quickly on its preferred instrumentation
vi. A good commercial LDMS will help you present your lab in a professional manner to
collaborators and granting bodies by enabling you to manage samples and workflows
from end-to-end, ensuring the highest quality traceable results, and substantially
improving overall lab efficiency and operations (Tomiello, 2007).
Coping with the ongoing and significant rise in the throughput and volume of data
associated with sequencing runs
Finding scalable methods to organize and track samples and associated data
Maintaining connections between samples and associated data from the moment
samples enter the lab to when data is reported
Reducing the amount of time spent processing and manually managing samples
Storing and retrieving data associated with projects, whether they were conducted
yesterday or last year
Maintaining in-house solutions such as Microsoft Excel or homegrown systems that are
easy to use and relevant to the instruments and protocols necessary to move research
programs forward
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while at the same time having the richest catalogue of modular laboratory management
software functionality from which to draw when deciding how to implement your LDMS
system (Wood, 2007).
2.3 Instrument and application integration
Modern LDMS offer an increasing amount of integration with laboratory instruments and
applications. A LDMS may create control files that are "fed" into the instrument and direct its
operation on some physical item such as a sample tube or sample plate. The LDMS may then
import instrument results files to extract data for quality control assessment of the operation
on the sample. Access to the instrument data can sometimes be regulated based on chain of
custody assignments or other security features if need be.
Modern LDMS products now also allow for the import and management of raw assay
data results (Gibbon 2006). Modern targeted assays such as qPCR and deep sequencing can
produce tens of thousands of data points per sample. Furthermore, in the case of drug and
diagnostic development as many as 12 or more assays may be run for each sample. In order
to track this data, a LDMS solution needs to be adaptable to many different assay formats at
both the data layer and import creation layer, while maintaining a high level of overall
performance. Some LDMS products address this by simply attaching assay data as BLOBs to
samples, but this limits the utility of that data in data mining and downstream analysis
(Mclelland, 2008).
2.4 Electronic data exchange
The exponentially growing volume of data created in laboratories, coupled with increased
business demands and focus on profitability, have pushed LDMS vendors to increase
attention to how their LDMS handles electronic data exchanges (Skobelev, 2006). Attention
must be paid to how an instrument's input and output data is managed, how remote sample
collection data is imported and exported, and how mobile technology integrates with the
LDMS. The successful transfer of data files in spreadsheet and other formats, as well as the
import and export of data to MySQL, and other databases is a pivotal aspect of the modern
LDMS (O’Leary, 2012). In fact, the transition "from proprietary databases to standardized
database management systems such as MySQL" has arguably had one of the biggest impacts
on how data is managed and exchanged in laboratories (McLelland, 2008). In addition to
mobile and database electronic data exchange, many LDMS support real-time data exchange
with Electronic Health Records used in core hospital or clinic operations (Khan, 2009).
2.5 Client-side options
A LDMS has utilized many architectures and distribution models over the years. As
technology has changed, how a LDMS is installed, managed, and utilized has also changed
with it. The following represents architectures which have been utilized at one point or
another.
2.5.1 Thick-client
A thick-client LDMS is a more traditional client/server architecture, with some of the system
residing on the computer or workstation of the user (the client) and the rest on the server
(Wood, 2007). The LDMS software is installed on the client computer, which does all of the
data processing. Later it passes information to the server, which has the primary purpose of
data storage. Most changes, upgrades, and other modifications will happen on the client side
(Wilkerson et al., 2014). This was one of the first architectures implemented into a LDMS,
having the advantage of providing higher processing speeds (because processing is done on
the client and not the server). Additionally, thick-client systems have also provided more
interactivity and customization, though often at a greater learning curve. The disadvantages
of client-side LDMS include the need for more robust client computers and more time-
consuming upgrades, as well as a lack of base functionality through a web browser. The
thick-client LDMS can become web-enabled through an add-on component (Skobelev, 2011).
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Although there is a claim of improved security through the use of a thick-client LDMS
(Skobelev, et al., 2011), this is based on the misconception that "only users with the client
application installed on their PC can access server side information". This secrecy-of-design
reliance is known as security through obscurity and ignores an adversary's ability to mimic
client-server interaction through, for example, reverse engineering, network traffic
interception, or simply purchasing a thick-client license. Such a view is in contradiction of
the "Open Design" principle of the National Institute of Standards and Technology's Guide to
General Server Security which states that "system security should not depend on the secrecy
of the implementation or its components" (Tomiello, 2007), which can be considered as a
reiteration of Kerckhoffs's principle.
2.5.2 Thin-client
A thin-client LDMS is a more modern architecture which offers full application functionality
accessed through a device's web browser. The actual LDMS software resides on a server
(host) which feeds and processes information without saving it to the user's hard disk (Khan,
2009). Any necessary changes, upgrades, and other modifications are handled by the entity
hosting the server-side LDMS software, meaning all end-users see all changes made. To this
end, a true thin-client LDMS will leave no "footprint" on the client's computer, and only the
integrity of the web browser need be maintained by the user. The advantages of this system
include significantly lower cost of ownership and fewer network and client-side maintenance
expenses (Wood, 2007). However, this architecture has the disadvantage of requiring real-
time server access, a need for increased network throughput, and slightly less functionality. A
sort of hybrid architecture that incorporates the features of thin-client browser usage with a
thick client installation exists in the form of a web-based LDMS (Wilkerson et al., 2014).
Some LDMS vendors are beginning to rent hosted, thin-client solutions as "software as a
service" (SaaS). These solutions tend to be less configurable than on-premises solutions and
are therefore considered for less demanding implementations such as laboratories with few
users and limited sample processing volumes. Another implementation of the thin client
architecture is the maintenance, warranty, and support (MSW) agreement. Pricing levels are
typically based on a percentage of the license fee, with a standard level of service for 10
concurrent users being approximately 10 hours of support and additional customer service, at
a roughly N450.000 per hour rate.[4]Though some may choose to opt out of an MSW after the
first year, it's often more economical to continue the plan in order to receive updates to the
LDMS, giving it a longer life span in the laboratory (O’Leary, 2012).
2.4.3 Web-enabled
A web-enabled LDMS architecture is essentially a thick-client architecture with an added
web browser component. In this setup, the client-side software has additional functionality
that allows users to interface with the software through their device's browser (Freidman,
208). This functionality is typically limited only to certain functions of the web client. The
primary advantage of a web-enabled LDMS is the end-user can access data both on the client
side and the server side of the configuration. As in a thick-client architecture, updates in the
software must be propagated to every client machine. However, the added disadvantages of
requiring always-on access to the host server and the need for cross-platform functionality
mean that additional overhead costs may arise.
2.4.4 Web-based
A web-based LDMS architecture is a hybrid of the thick- and thin-client architectures. While
much of the client-side work is done through a web browser, the LDMS may also require the
support of desktop software installed on the client device. The end result is a process that is
apparent to the end-user through a web browser, but perhaps not so apparent as it runs thick-
client-like processing in the background. In this case, web-based architecture has the
advantage of providing more functionality through a more friendly web interface. The
disadvantages of this setup are more sunk costs in system administration and reduced
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functionality on mobile platforms (O’Leary, 2012). The disadvantage of a thick client is in
the installation and update phases of the applications. Users who want the security, high
speed and functionality of a thick client may use Microsoft ClickOnce Technology. This
enables the user to install and run a Windows-based smart client application by clicking a
link in a web page (Friedman, 2008). The software does not need to be installed at each user
workstation one by one. ClickOnce applications can be self-updating; they can check for
newer versions as they become available and automatically replace any updated files (Royce,
2010).
2.4.5 Configurability of Laboratory Database of Management System
LDMS implementations are notorious for often being lengthy and costly. This is due in part
to the diversity of requirements within each lab, but also to the inflexible nature of LDMS
products for adapting to these widely varying requirements. Newer LDMS solutions are
beginning to emerge that take advantage of modern techniques in software design that are
inherently more configurable and adaptable particularly at the data layer than prior solutions.
This means not only that implementations are much faster, but also that the costs are lower
and the risk of obsolescence is minimized.
2.5 Distinction between a LDMS and LIS
Until recently, the LDMS and Laboratory Information System (LIS) have exhibited a few key
differences, making them noticeably separate entities. A LDMS traditionally has been
designed to process and report data related to batches of samples from biology labs, water
treatment facilities, drug trials, and other entities that handle complex batches of data. A LIS
has been designed primarily for processing and reporting data related to individual patients in
a clinical setting. A LDMS may need to satisfy good manufacturing practice (GMP) and meet
the reporting and audit needs of the regulatory bodies and research scientists in many
different industries. A LIS, however, must satisfy the reporting and auditing needs of health
service agencies e.g. the hospital accreditation agency, HIPAA in the US, or other clinical
medical practitioners. A LDMS is most competitive in group-centric settings (dealing with
"batches" and "samples") that often deal with mostly anonymous research-specific laboratory
data, whereas a LIS is usually most competitive in patient-centric settings (dealing with
"subjects" and "specimens") and clinical labs. An LIS is regulated as a medical device by the
FDA, and the companies that produce the software are therefore liable for defects. Due to
this, an LIS cannot be customized by the client.
2.6 Content Management System
Content Management System (CMS) is an application which is used for managing several
methods related with web publishing. Based on Douglas et al., (2006) a CMS generally
can be customized by adding or subtracting specific feature, so that only several
features needed which will be published to the user. Currently, CMS is widely used to
create bulletin board, online trading website, community website, online photo gallerym
and so on. Fraser and Stephen (2002) explained that Content Management System consists
of at least three elements:
Content Management Application (CMA). CMA will manage application
content components, including picture, text, and so on.
Meta-content Management Application (MMA). MMA will manage information
carried by application content components.
Content Delivery Application (CDA). CDA will pick content components, read
the information within, and render the result for user consumption.
One of several various kind CMS is used and implemented for laboratory. It is called
LDMS (Laboratory Database Management System). LDMS, based on Crandall et al.,
(2007) can be explained briefly as a combination between software and computer
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hardware used in laboratory to manage laboratory sample, user, instrument, standard and
other functionalities using database, report generator and computer network capabilities.
8
AMAOKWE GENERAL HOSPITAL
ISHIAGU
Pharmacist Workers
9
3.3.1 Input Analysis
This deals with the process used to feed data to the system for processing. Here the inputs to
the system are through staff record form, and attendance scheme for Laboratory Unit
form. All these are through which data are supplied to the system which are Employee name,
employee number, sex, age, marital status, address, phone number, L.G.A, State, Job
description, salary, qualification, starting time, ending time, date, work description, and
remark (if any).
3.3.2 Process Analysis
Once the inputs are collected, the obtained data are processed properly for effective use. The
data/information processed is stored in the computer for subsequent use.
3.3.3 Output Analysis
This involves the resultant documentation generated after the processing of
data/information supplied to the system. The output here can be:
1. Printed roster card
2. Store Laboratory Scientist/Attendance data
3.4 Limitations of the Existing System
A lot of problems are associated with the existing system. The existing system
involves the use of manual method to store duty data/information. The system has proved
defective as the objective of the system has also failed. Among the problems
associated with the existing system include the following:
1. Time wasted in searching/sorting for workers duty information.
2. Poor security and protection.
3. Misplacement and mismanaging of checkup and treatment files.
4. A lot of time being wasted by patient while on queue.
3.4.1 Justification for the New System
It is expected that the introduction of the new system, a lot of positive changes will be
noticed. The numerous problem associated with the manual system will be minimized,
if not totally put to an end. The hospital staff that previously had difficulties in
carrying out their work will now have to appreciate it. Head Lab Scientist supervise
Laboratory activities in a variety of settings. While some patient diagnosis specimen is
usually required, the Laboratory supervisor’s new duties to a Laboratory Attendance,
and ensuring that each member of the Hospital Laboratory team is adequately trained. Head
Laboratory Scientist are ultimately responsible for the performance of the Lab
Attendance on their team. This means that they must ensure that ensure that Hospital
Laboratory records are correctly maintained, that report is correctly given at the shift
change, and that equipment and other supplies are in stock.
3.5 System Design
Files are necessary in monitoring of patients Diagnostic Medical Result record since there are
many patients whose Diagnostic Medical Result records must be kept for references purpose.
This fact has given rise to the creation and maintenance of several files within the company.
Below are various files and their uses:
Request File: This file contains the request from Doctors who wish to access patient
diagnostic/medical result based on their conditions.
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Diagnostic File: this is the file that contains information about Laboratory Test and
Result of the Patient.
Return File: After the Doctors Examination and Recommendations must have been
sent carried out, return forms are sent back to the pharmacy specifying the types
of drugs, cost, dosage and the receipt.
Complaint File: This file used to help all complaints from Nurses and Medical
Doctors which wish to access patient file on revisit.
3.5.1 Input Design and Specification
The input to the system comes with various forms. Each of these forms has the function of
collecting specific data from the Med-Lab, doctors, staff and patients as the case may be.
The first form is the admission form details that enables the system to prompt the
Doctors/Nurses to fill a form that requires details from the patient concerning personal and
health. The other forms are for Lab Scientist, doctors, Nurses, bed management, patient in
and out, etc are solely intended for the administrative use for the staff. Here, the staff can
add patients, doctors etc that can include the services render by the hospital and change other
things.
Patient Form
Name of Patient
Sex:
Date of Birth:
State of Origin:
Nationality:
Phone No:
Blood Group:
Genotype:
Address:
Guidance:
Patient ID No:
Health Record:
Submit
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administer drug, monitor, supervise and pay close attention to patients even after they
have been discharged.
Laboratory-Diagnostic Form
Name of Lab-Scientist:
Position:
Phone No:
Staff ID No:
Name of Patient:
Patient ID No:
Health Record:
Laboratory Result:
Lab-Attendance Recommendations:
Dr. ID No:
Name:
State:
Address:
Phone No:
Email Address:
Specialization:
Qualification:
Report/Counseling: Submit
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Fig 3.4: Doctors Form
The Doctors form, as mentioned earlier, is primarily used by the hospital
administrators to add Doctors that are employed with the hospital, and can accept patients for
proper treatment and admission. Looking at the form above, there has been provision made
for personal details of the Doctors and specialization before saving to the database.
HOSPITAL SERVICE FORM (LAB FORM)
Blood Test:
Genotype:
Hiv/Aid Test:
Pregnancy Test:
STI Test:
Eye Test:
Maternity Test:
X-ray:
Lab-Attendance Recommendations:
Submit
General Operation
Manager
Metron
Nurses
Cashier
Computer13Operator
Workers etc.
Fig. 3.7: Information Flow Diagram
The Information Flow Chart shows how the information are kept and transferred to
various department heads for easy accessibility.
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Fig 3.8 System Flow Chart
The figure above is a system flow chart. The system flow chart is a valuable presentation
aid because it shows how the system’s major components fit together. In effect, it serves as
a system road map. The system flow chart shows the key inputs and outputs associated
with the program. The shape of the symbols indicate the types of input or output devices.
Start
Search results
Is result Yes
Display result
available
?
No
Is result Yes
positive? Display result
No
Is result Yes
Display result
negative?
No
Display laboratory
data
15 Stop
Fig. 3.9: Program Flow Chart
B
Display Lab-Scientist
Information Form
Fill more
Form
Stop
Fill more
Form
Exit
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D
Reply Display
Fill more
Form
Exit
Reply Display
Process
Form
Exit
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Fig. 3.9: Program Flowchart
System Driver
Add Record
Laboratory Staff
Register Lab-
Scientist
Del. Record
List of Lab. Cases
Register Doctor Pharmacy Update Rec.
List of Department
Create User
List of Lab-Scientist
Exit
Exit
Exit Exit
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System Block Diagram
The diagram show the sequence of operation of the new Laboratory Database Management
System and the different stages or steps involved in it.
Sample Experimental
Conduct Experiment
Sample Results
Fig. 11: System Block Diagram
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Hp Laptop with following configurations;
1. Storage: 500 gigabyte of storage.
2. Memory: 4GB of ram and above.
8. Printer: Optimal (Colored/black and white)
4.2.2 Software Requirements
Computer software is a collection of computer programs and related data that provides
the instructions for telling a computer what to do and how to do it. In other words,
software is a set of programs, procedures, algorithms and its documentation concerned
with the operation of a data processing system. Program software performs the function of
the program it implements, either by directly providing instructions to the computer
hardware or by serving as input to another piece of software. The following list of
software are needed for adequate implementation of the system
1. Window windows 8 and above
2. PHP
3. MYSQL
4. Anti-virus program (updated).
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