PRIORITY CONCEPT: ANXIETY, MOOD AND AFFECT

NOTE:

 SERATONIN IS A KEY HORMONE THAT STABILIZES MOOD, FEELINGS OF WELL-BEING AND HAPPINESS.

 ENABLES BRAIN CELLS TO COMMUNICATE WITH OTHER NERVOUS SYSTEM CELLS. SERATONIN ALSO HELPS WITH DIGESTION, SLEEPING AND EATING.

 CONTRAINDICATED WITH MONOAMINE OXIDASE (MAO) INIHIBITORS

MEDICATIO
MEDICATION PARAMETERS
N MECHANISM ADVERSE
CATEGORY (BRAND / INDICATION SIDE EFFECTS (VITAL NURSING INTERVENTIONS LABS
(GENERIC OF ACTION EFFECTS
TRADE NAME) SIGNS)
NAME)
SELECTIVE Citalopram  Celexa Selectively  DEPRESSION  Dry mouth  Monitor vital signs b/c  Patients on long term
SEROTONIN inhibits the  Changes in SSRIs can potentially therapy, monitor:
REUPTAKE reuptake of  ANXIETY blood pressure lower or elevate blood Liver and renal function
INHIBITORS Escitalopram  Cipralex serotonin in  MAJOR DEPRESSIVE changes pressure. test results (altered
(SSRIs):  Lexapro the CNS. DISORDER  Insomnia /  Teach patient, values may occur,
 GENERALIZED somnolence medication may cause requiring dosage
INHIBIT Antidepression ANXIETY DISORDER (sleepy, sexual dysfunction and to adjustments).
SEROTONIN action. drowsy) inform HCP if occurs.  Monitor:
REUPTAKE AND Fluoxetine  Prozac Selectively  MAJOR DEPRESSIVE  Apathy (lack of  Initiate precautions and (meds may be
ELICIT AN inhibits the DISORDER interest) contact HCP if dizziness discontinued if levels
ANTIDEPRESSAN reuptake of  Tremors occurs. decrease below normal)
T RESPONSE serotonin in  OBSESSIVE  Seizure activity o Instruct pt. to o WBC
the CNS. COMPULSIVE  Nervousness change positions o Neutrophil counts
DISORDER (OCD)  +/- Weight slowly if o
Antidepression  Decreased experiencing a
action.  BULIMIA NERVOSA libido hypotensive
effect.
Decreased  PANIC DISORDER  Enters the breast milk.
behaviors Women should not be
associated  ACUTE TREATMENT breastfeeding on this
with: panic OF DEPRESSIVE drug.
disorder, EPISODES  Monitor suicidal client,
bulimia. ASSOCIATED WITH especially during
Decreased BIPOLAR I DISORDER improved mood and
mood (WHEN USED WITH increased energy levels.
alterations OLANZAPINE)  Teach client that taking
associated Ibuprofen with SSRIs
with PMDD  TREATMENT increases the risk of an
RESISTANT upper GI bleed.
DEPRESSION WHEN  Abrupt cessation can
USED WITH lead to serotonin
OLANZAPINE)
 PRIORITY CONCEPT: ANXIETY, MOOD AND AFFECT

NOTE:

 SERATONIN IS A KEY HORMONE THAT STABILIZES MOOD, FEELINGS OF WELL-BEING AND HAPPINESS.

 ENABLES BRAIN CELLS TO COMMUNICATE WITH OTHER NERVOUS SYSTEM CELLS. SERATONIN ALSO HELPS WITH DIGESTION, SLEEPING AND EATING.

 CONTRAINDICATED WITH MONOAMINE OXIDASE (MAO) INIHIBITORS

withdrawal characterized
 PREMENSTRUAL by gastrointestinal
DYSPHORIC distress, movement
DISORDER (PMDD) disorders, insomnia and
sensory disturbances.
Fluvoxamine  Encourage
psychotherapy
 Be aware of potential for
Paroxetine serotonin syndrome,
characterized by(risk
increased when given
with MAOIs):
Sertraline
o Hypersensitivity
o Restlessness,
o Tachycardia
Vilazodone
o Fever
o Elevated blood
pressure
o Altered mental
status (delirium)
o Mood swings
o Seizures
o Muscle rigidity
o Abdominal pain
 Teach pt. OTC cold meds
may increase likelihood
of serotonin syndrome.