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Chromosomal Theory of Inheritance

Walter Sutton and Theodore Boveri in 1902 united the knowledge


of chromosomal segregation with Mendelian principles and called it
chromosomal theory of inheritance.
According to this theory,
(1) All hereditary characters are carried with sperms and egg cells,
as they provide bridge from one generation to the other.
(i) The hereditary factors are carried in the nucleus.
ii) Chromosomes are also found in pairs like the Mendelian alleles.
iv) The two alleles of a gene pair are located on homologous sites on
the homologous chromosomes.
(v) The sperm and egg have haploid sets of chromosomes, which
fuse to re-establish the diploid state.
(vi) The genes are carried on the chromosomes.
(vii) Homologous chromosomes synapse during meiosis and get
separated to pass into different cells. This is the basis for
segregation and independent assortment.
Meiosis-ll Germ cells
G2 Meiosis-
anaphase anaphase

Bivalent

Meiosis and germ cell formation in a cell with four chromosomes

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