Warfarin

Pendahuluan
Farmakologi
Farmakokinetik
Absorpsi
Distribusi
Metabolisme
Eliminasi
Farmakodinamik
Clinical Utility
Practical Engagement and Education
Dosis
Inisiasi
Maintanance
Administrasi
Monitoring
Transitioning between warfarin and other anticoagulant
Management of Warfarin around elective procedures
Adverse Effects
Bleeding events
Special Considerations Low Molecular Weight Heparin

Unfractioned Heparin and Low Molecular Weight Heparin

UFH
Farmakokinetik dan farmakodinamik
Indikasi klinis dan dosis
Monitoring
Special Population
Strategies for Reversal of Unfractioned Heparin
Complication

Low Molecular Weight Heparin

Farmakodinamik
Farmakokinetik
Indikasi klinis dan dosis
Special populations

Parenteral Anticoagulants : Direct Thrombin Inhibitors and Pentasaccharides

Parenteral Direct Thrombin Inhibitors (Argatroban and Bivalirudin)

Farmakologi
Farmakokinetik
Farmakodinamik
Utilitas klinik
HIT (Heparin-Induced Thrombocytopenia)
Argatroban
Bivalirudin
Practical Management
Dosis
Administrasi

Monitoring dan Titrasi

HIT

Transitioning to Oral Anticoagulation

HIT
Argatroban
Bivalirudin

Other Clinical Uses

CRRT
ECMO

Fondaparinux
Farmakologi
Farmakokinetik
Farmakodinamik
Clinical Utility
Practical Management
Dosis
Administrasi
Monitoring
Transitioning Between Anticoagulants
Transitioning from Fondaparinux
Transitioning to Fondaparinux
Adverse Effects
Special Considerations

Direct Oral Anticoagulants

Pendahuluan
DTI (Direct Thrombin Inhibitors)
Farmakologi
Indikasi
Direct factor Xa Inhibitor
Farmakologi

Rivaroxaban
Apixaban
Edoxaban

Perioperative Management
Manajemen perdarahan/drug reversal

Anticoagulation Reversal
Vitamin K Antagonis
Overview of Anticoagulation with warfarin
Vitamin K
Warfarin Reversal prior to surgery
Plasma
Prothrombin complex concentrates
Recombinant factor VIIa

Heparin

Pentasaccharides

Parenteral Direct Thrombin Inhibitors (DTIs)

Oral Direct Thrombin Inhibitor

Direct Oral Factor Xa Inhibitors