Drug Study

Drug name Mechanism Indication Contradiction Adverse Nursing

of action Effect/Side Effects Responsibilities

Generic Name Calcium channel For the Known -Constipation Before

Nifedipine blocking agent management of hypersensitivity • Concurrent
that selectively vasospastic reaction to -difficulty therapy of
Brand Name blocks ion influx angina, chronic nifedipine breathing or sublingual
Adalat, Procardia, across cell stable angina .
swallowing nitroglycerin may
Afeditab,Nifediac membranes of and be used for relief
cardiac muscles hypertension. -dizziness or of anginal pain.
Actual dosage, lightheadedness
and vascular
route, frequency • Record onset,
smooth muscle
PO: ADULTS, -enlargement of type (sharp, dull,
ELDERLY: Initially, without changing squeezing),
serum calcium gum tissue
10 mg 3 times a radiation,
concentrations. around teeth
day. Increase at location,
7- to 14-day Class IV intensity,
intervals. antiarrhythmic -fast heartbeat duration of
Maintenance: 10 anginal pain;
mg 3 times a day -flushing (feeling precipitating
up to 30 mg 4 of warmth) factors (exertion,
times a day. emotional stress).
-Headache
PO (Extended • Check B/P for
Release): hypotension
ADULTS, immediately
ELDERLY: Initially, before giving
30–60 mg/day. medication.
May increase at
7- to 14-day During
intervals. • Assist with
Maximum: 120– ambulation if
180 mg/day. light-headedness,
Essential dizziness occurs.
Hypertension
PO (Extended •Assess for
Release): peripheral
ADULTS, edema.
ELDERLY: Initially,
30–60 mg/day. • Assess skin for
May increase at flushing.
7- to 14-day
intervals. • Monitor serum
Maximum: 90– hepatic enzymes
120 mg/day. .
• Observe for
signs/ symptoms
of CHF.

After
• Rise slowly from
lying to sitting
position, permit
legs to dangle
from bed
momentarily
 Drug name Mechanism Indication Contradiction Adverse Nursing
of action Effect/Side Efects Responsibilities

Brand Name Magnesium Prevention of Magnesium -nausea, diarrhea, Before

MgSO4 sulfate is thought seizures in sulfate or vomiting Prior to
to trigger cerebral eclampsia/preecla (magnesium -large drops in administration:
Generic Name vasodilation, thus mpsia. sulfate blood pressure ■ Obtain a
Magnesium reducing ischemia (magnesium -slow or irregular complete health
Sulfate generated by Acute nephritis sulfate injection) heart rate history including
cerebral (pediatric injection) should -breathing allergies, drug
Drug Class vasospasm during patients) not be problems history, and
Antidysrhythmics, an eclamptic administered -deficiencies in possible drug
V; Electrolytes event. The Cardiac parenterally in minerals other interactions.
substance also arrhythmias patients with heart than magnesium, ■ Assess
DOSAGE acts competitively secondary to block or especially calcium respiratory status
4g in blocking the hypomagnesemia myocardial -confusion or and deep tendon
entry of calcium . damage. fogginess reflexes.
ROUTE into synaptic -coma ■ Assess for the
IV endings, thereby Soaking minor -heart attack presence or
altering cuts or bruises. -kidney damage history of
FREQUENCY neuromuscular malnutrition,
OD transmission. hypomagnesia,
seizure activity,
TIMING: preeclampsia,
15-20mins. and kidney
disease.
■ Obtain serum
magnesium level
and renal profile
DURING
■ Verify a
patient's identity.
■ Check patient’s
status.
■ Inform the
client/SO the
purpose of the
drug.
■ Assess route of
administration.
■ Administer on
time.
AFTER:
■ Monitor
patient’s
accordingly.
■ Ensure
patient’s safety.
■ The client
verbalizes sides
effects that
require reporting.
■ The client
demonstrates an
understanding of
the drug’s action
by accurately
describing drug
side effects and
precautions.