Lecture 3

06/27/2022
 ● Google classroom & google chat
● Review of lecture 2
Agenda ● Pop quiz
● Ion channels/ion pumps
● Synaptic transmission
Classroom & Chat
Classroom: https://classroom.google.com/u/0/c/NDg4MDg0MjUxNzQ1

Chat: https://mail.google.com/chat/u/0/#chat/welcome
Review
Glial cells
Myelinating glia (Schwann cells)

● Provide layers of membrane

that insulate axons
● regulating the speed of the
nerve propagation down the
axon

Astrocytes

● Regulate the chemical content of the

extracellular space (cytosol)
● have special proteins in their membrane that
actively remove neurotransmitters from the
synaptic cleft
Action potential
Action potential propagation
https://www.youtube.com/watch?v=Sa1wM750Rvs
Quiz
https://forms.gle/wcDbFcvsCTTRBSrDA
 ● Ion channels:
○ Ligand-gated
○ Voltage-gated
Ion channels/Ion ○ Mechanically-gated

pumps
● Ion pumps
Ligand-gated
Voltage-gated
Mechanically-gated
● Open and close in response to mechanical vibration or pressure, such as sound
waves or the pressure of touch (found in sensory receptors in the skin, ear, etc.)
Ion pumps
Synaptic transmission
Chemical synapse
Receptors
G-protein coupled receptors (GPCRs)
Electrical synapse
● Happens at specialized sites called gap junctions.
Questions?
References
● Neuroscience Exploring The Brain, third edition by Mark F. Bear, Barry W. Connor,
Michael A. Paradiso, 2007
● Wikipedia
● 9.01 lecture slides by Mark Bear, 2020
● 9.13 lecture slides by Nancy Kanwisher, 2022
● Youtube video from Cambridge University, 2017
● Youtube - Two minute neuroscience channel