Name of the

Breakdown person raising the Contact person from Severity of the

Timestamp equipment/Area Give brief details of the issue request Date of reporting Current status of the issue Engineering problem Closed by Remarks
5/23/2014 9:17:36 mobile tank 4 CIP spray not rotating sathish 2/15/2014 4:10:00 Please open and clean if still doesnt work let us know Sayeed low Sayeed
MDV in cip inlet line passing
5/23/2014 9:18:39 media vessel 2 observed. sathish 2/15/2014 4:40:00 Completed Hindo
5/23/2014 9:20:00 dosing vessel 01 vessel top lid leakage observed manikandan 3/17/2014 8:10:00 Gasket replaced Sayeed high Sayeed
pure steam header valve passing is
5/23/2014 9:20:43 250L fermenter there manikandan 3/17/2014 10:15:00 Completed Sayeed/Hindo medium Hindo
pure steam header valve TC gasket
5/23/2014 9:21:37 5KL Fermenter leakage observed manikandan 3/21/2014 8:05:00 Completed medium Hindo, Ganesh
CIP inlet diaphragm valve to
upstream near harvesting vessel is
5/23/2014 9:22:43 CIP line leaking manikandan 3/25/2014 11:15:00 completed Dinesh
all wooden cupboard doors are came
5/23/2014 9:23:43 upstream area out manikandan 3/25/2014 10:05:00 completed Ganesh.R medium Ganesh.R
5/23/2014 9:25:16 5KL fermenter CIP spary balls are not rotating manikandan 4/4/2014 23:15:00 Please open and clean if still doesnt work let us know Sayeed low Sayeed
air fine filter drain valve and after
filter drain valve are leakage
5/23/2014 9:26:06 media vessel 02 observed manikandan 4/7/2014 22:40:00 Completed Ganesh
diaphragm vave leakage before CIP
5/23/2014 9:26:37 250L fermenter valve m 4/7/2014 23:10:00 Completed Hindo
5/23/2014 9:27:26 250L fermenter sample valve leakage observed manikandan 4/12/2014 15:10:00 rectified Sayeed/Hindo medium
Lights in Final goods area, corridor,
unclean utensils area, fermenter
5/23/2014 9:28:26 BPM facility room are NOT GLOWING. manikandan 4/14/2014 22:15:00 Completed low
flange leakage near to AAPV-04
5/23/2014 9:29:08 Media Vessel-01 value observed. sathish 4/14/2014 23:15:00 Completed Hindo
handle leakage observed in half inch
line values of Transfer line. (both
drain line and 15L fermenter transfer
5/23/2014 9:29:55 250L fermenter line value) sathish 4/4/2014 23:30:00 Completed Hindo, Dinesh
UF Tank -
5/23/2014 9:31:44 Downstream In Jacket pin hole leak observed suresh 5/14/2014 14:55:00 Completed yadav
diaphragm valve leakage was Diaphragm found punchred,replaced with new
5/26/2014 16:33:57 dosing vessel 01 observed before air fine filter manikandan 5/26/2014 14:10:00 diaphragm checked and found no leakage. Ganesh Medium Ganesh
Steam diaphragm valve leakage was
5/27/2014 19:51:09 Media vessel 02 observed after fine filter manikandan 5/27/2014 17:10:00 Completed Ganesh
Transfer line drain valve leakage
5/27/2014 19:53:00 250L fermenter was observed manikandan 5/27/2014 19:05:00 Completed
SRV setup breakdown to be
5/28/2014 13:16:56 media vessel 01 addressed. irfan 5/27/2014 6:15:00 Completed Ganesh Medium Ganesh & Dinesh
After bottom valve Drain MDV &
vessel isolation MDV for 5KL
5/28/2014 13:19:33 250 L Fermenter diaphragm puncher. Vishwanath 5/28/2014 Completed Hindo Medium Hindo & Lokesh
steam header MDV is damage
5/28/2014 13:22:29 250 L fermenter leaking heavily irfan 5/28/2014 8:00:00 Completed Hindo Medium Hindo & Ganesh
Level sensor is not working showing
5/28/2014 13:39:06 Media vessel 01 358L only. Vishwanath 5/28/2014 13:00:00 Completed Prabu/Sachin Prabu
Planned to replace
vessel pressure gauge is not working the transmitter and
5/29/2014 6:44:15 5kl fermenter .. Irfan 5/29/2014 6:50:00 completed Prabu/Sachin high check ,next batch
vessel temperature sensor is
5/29/2014 13:32:16 5KL fluctuating . Irfan 5/29/2014 13:32:00 completed Prabu/Sachin
Sample vavle steam inlet diaphragm
5/30/2014 18:31:14 5KL fermenter valve leakage was observed. manikandan 5/30/2014 14:25:00 Completed Hindo & Ganesh
Dosing vessel 02 Flush bottom valve steam diaphragm
5/30/2014 18:37:22 valve leakage was observed manikandan 5/30/2014 16:05:00 Completed Hindo
Found leakage in heater coil gesket,removed and Ganesh,Hindo &
6/4/2014 6:04:24 Autoclave bottom is leaking Irfan 6/6/2014 4:06:00 replaced all 3 nos heater coil gasket. Ganesh High Prabhu
spray ball vessel isolation valve
6/4/2014 6:06:20 dosing vessel 01 MDV is passing irfan 6/6/2014 5:07:00 completed Ganesh Medium Ganesh
VERTICAL Found leakage in heater coil gesket,removed and Ganesh,Hindo &
6/5/2014 9:16:24 AUTOCLAVE Drain valve leakage manikandan 6/5/2014 9:14:00 replaced all 3 nos heater coil gasket. Ganesh High Prabhu
Transfer line steam diaphragm valve
6/5/2014 9:44:51 Media vessel 01 leakage was observed. manikandan 6/5/2014 9:45:00 Completed Hindo
CIP pump seal leakage was
6/6/2014 9:39:08 CIP tank observed manikandan 6/6/2014 9:20:00 Completed Ganesh.R High Ganesh
6/7/2014 6:11:18 5LK fermenter Mechanical seal is leaking Irfan 6/6/2014 4:14:00 completed Ganesh / Hindo High Team
agitator gear box oil leakage
6/7/2014 6:12:40 5KL fermenter Irfan 6/6/2014 3:09:00 completed(New oil seal fixed) Ganesh High Ganesh & Hindo
6/7/2014 6:15:02 Media vessel 01 jacket vent safety setup damage Irfan 6/7/2014 6:18:00 Completed Ganesh Medium Ganesh & Sayeed
Found panel exhaust fan's power MCB-off state.Same
6/7/2014 10:06:00 5KL fermenter Agitator automatically tripped manikandan 6/7/2014 10:00:00 switched on and no temperature issues now Prabu High Prabu
6/7/2014 11:41:25 250 L fermentoer steam header MDV is leaking Irfan 6/6/2014 2:07:00 Completed Hindo
6/10/2014 11:25:17 5KL fermenter Sample leakage observed. Sathish E 6/10/2014 11:25:00 Completed Ganesh medium Ganesh & Hindo
Transfer line MDV leakage observed
through the bolt. (REAC feed leaked
6/11/2014 12:12:46 Media vessel 02 during batch) Sathish E 6/11/2014 12:10:00 Completed Hindo
Steam/CIP Main inlet valve (ADV)
6/11/2014 12:19:22 5 KL fermenter condensate leakage observed vinod 6/11/2014 12:15:00 Completed Hindo
Set the pressure to
6/12/2014 19:01:20 Dosing vessel 02 SRV leaking at 1.5bar only. Vishwanath 6/12/2014 19:00:00 Completed Abhijith Medium Abhijith 3.8 bar
sample valve handle continuously
6/12/2014 22:53:27 250L fermenter rotating manikandan 6/12/2014 22:15:00 Completed Chakravarty High Chakravarty
6/14/2014 2:41:41 250L fermenter pH probe showing wrong value manikandan 6/13/2014 6:11:00 completed Prabu/Sachin Medium Prabu/sachin
Exhaust PID valve continuously
6/14/2014 2:47:43 5KL fermenter fluctuation manikandan 6/14/2014 1:00:00 Completed Prabu High Prabu
250L fermenter TC clamp next to chilled water return
6/14/2014 13:46:08 utility line line, leakage observed. Sathish E 6/14/2014 13:45:00 Completed Ganesh medium Ganesh
6/15/2014 9:36:57 Media vessel 01 jacket pressure gauge is not working irfan 6/15/2014 8:08:00 completed Prabu prabu/sachin
6/15/2014 9:43:24 5000 L fermenter DO probe 104 is malfunctioning irfan 6/15/2014 10:00:00 completed Prabu high prabu/sachin
Jacket drain valve passage
6/16/2014 9:05:40 Media vessel 02 observed. Sathish E 6/16/2014 9:05:00 Completed Ganesh medium Ganesh
Thermosyphon condensate level not
6/16/2014 9:44:57 5 KL fermenter maintaining. Sathish E 6/16/2014 9:45:00 Completed Team High Sayeed
3 Lights is not working in fermenter
6/16/2014 18:43:09 Fermenter Room room Vishwanath 6/16/2014 18:40:00 Completed elec team elec team
Pass Box -
Production to QC When pass box door opens, either
6/17/2014 11:10:20 chemical one side, alarm sound is not coming. Sathish E 6/17/2014 11:10:00 Completed elec team yadav
Fumes observed in the panel
Continuous followed by VFD alarm. Not able to
6/19/2014 6:16:34 Centrifuge start centrifuge. Vinodh 6/19/2014 1:00:00 Completed Team sayeed
After air fine filter diaphragm valve
6/19/2014 20:28:32 media vessel 01 leakage was observed manikandan 6/19/2014 17:15:00 Completed Ganesh.R Midium Ganesh
PHE steam trap leakage was
6/27/2014 14:14:49 5KL fermenter observed. manikandan 6/27/2014 10:02:00 Completed Ganesh medium Ganesh
Changed swastik
diaphragm with
steam header diaphragm valve used GF
6/29/2014 13:38:09 250L fermenter leakage was observed manikandan 6/29/2014 8:01:00 Completed. Hindo medium Hindo diaphragm
thermosyphon chilled water inlet and
outlet diaphragm valve passing was
7/2/2014 11:46:13 5KL fermenter observed manikandan 7/2/2014 10:01:00 Completed Hindo medium Hindo
7/2/2014 17:54:13 Media vessel 01 air line MDV after filter is puncher Irfan 7/2/2014 17:09:00 Completed Hindo medium Hindo
jacket Steam inlet line pin hole
7/2/2014 17:55:29 Media Vessel 01 leakage after valve Irfan 7/2/2014 17:12:00 Completed Hindo medium Hindo
7/4/2014 12:15:43 Media vessel 01 Vessel lamp is not working Ritu 7/4/2014 12:15:00 Completed elec team medium yadav
Exhaust filter pressure gauge is not
7/5/2014 1:15:12 250L fermenter working manikandan 7/5/2014 1:00:00 completed Prabhu medium Prabu
Leakage observed in the agitator Seal spare parts
7/10/2014 10:04:55 Dosing Vessel-1 shaft Sathish E 7/10/2014 10:00:00 Completed. Hindo medium Team changed.
Upstream walky Not able to contact through walky
7/10/2014 13:40:46 talky talky, receiver problem Sathish E 7/10/2014 13:00:00 additional one given team team
7/13/2014 15:25:07 dosing vessel 02 top dish gasket damaged manikandan 7/12/2014 18:01:00 completed Ganesh.R Ganesh.R
perfusion vessel connected
7/13/2014 15:26:18 5KL fermenter diaphragm valve passing manikandan 7/12/2014 17:01:00 Completed Ganesh.R High Hindo, Ganesh
transfer line ADV
902,904,907,908,622 passing was
7/13/2014 15:27:51 5KL fermenter observed manikandan 7/13/2014 14:00:00 Completed Ganesh.R High Hindo, Ganesh
vessel pressure transmitter is not
7/13/2014 17:13:36 Media vessel 02 working Manikandan 7/13/2014 17:00:00 rectified yadav
 Name of the
Breakdown person raising the Contact person from Severity of the
Timestamp equipment/Area Give brief details of the issue request Date of reporting Current status of the issue Engineering problem Closed by Remarks
Temperature probe Temperature probe in Harvest
in Harvest Vessel- Vessel-01 is broken down, but it is in
7/20/2014 6:42:20 01 is broken down. working condition. Praveen Kumar 7/20/2014 6:30:00 completed sachin medium
Downstream -
Packing area Packing area Hygrometer is not
7/21/2014 2:51:29 Hygrometer showing any value. Sathish E 7/21/2014 2:55:00 working fine sayeed low sayeed
cooling water jacket inlet flange
7/27/2014 3:13:07 Media vessel 02 leakage was observed Manikandan 7/27/2014 1:00:00 Completed Abijith Medium Abijith & Lokesh
250L Fermenter
pure steam header diaphragm valve
7/27/2014 3:14:13 leakage Manikandan 7/27/2014 1:05:00 Completed Ganesh.R medium Ganesh & Lokesh
vessel top dish leakage was
7/27/2014 3:15:06 250L fermenter observed Manikandan 7/27/2014 2:00:00 Checked and No leakage found Ganesh.R Medium Ganesh
7/27/2014 3:28:17 250L fermenter agitator gear box oil leakage Manikandan 7/27/2014 2:00:00 completed Ganesh high Ganesh & Hindo
dosing vessel 02 vessel lamp is not
7/29/2014 9:24:04 Dosing vessel 02 working Praveen Kumar 7/29/2014 9:01:00 Rectified elec team yadav
Lamps are not working (immediately
after change room, in raw material
BPM production dispensing area, inside downstream
7/29/2014 9:26:52 plant area etc) Praveen Kumar 7/29/2014 9:15:00 Completed elec team Chakravarty & nigappa
Praveen Kumar G
7/29/2014 10:06:07 Holding vessel 03 Panel not switching on M 7/29/2014 10:04:00 Completed elec team Chakravarty
8/6/2014 2:25:41 Media vessel 02 Pressure transmitter malfunction Sathish E 8/6/2014 2:25:00 rectified yadav
Anti-foam sensor false alarm
observed (this has been noted from
the time of arresting leakage of that
8/6/2014 2:32:07 5kl fermenter TC clamp) Sathish E 8/6/2014 2:31:00 Completed Sachin/Prabhu Sachn/prabhu
8/6/2014 8:10:17 Dosing vessel 01 Drain MDV leak observed Vishwanath 8/6/2014 8:10:00 Completed Dinesh
Pressure transmitter showing wrong
8/6/2014 8:32:07 Media vessel 02 reading Vishwanath 8/6/2014 8:36:00 Completed Sachin
Hygrometer in
8/6/2014 13:53:20 filling room Display not showing Vishwanath 8/6/2014 9:38:00 Completed Sachin
media transfer line steam diaphragm
8/6/2014 15:44:31 5KL fermenter valve (AADV) leakage was observed Manikandan 8/6/2014 14:00:00 Completed Ganesh/Hindo Hindo, Dinesh
8/6/2014 15:54:39 250L fermenter sample valve leakage was observed Manikandan 8/6/2014 15:54:00 Completed Ganesh/Hindo Medium Ganesh & Hindo
8/6/2014 16:54:46 5KL fermenter M.seal leakage observed. Manikandan 8/6/2014 15:00:00 completed Ganesh/Hindo major team
After steam filter to 250L fermenter
Main pure steam flange condensate leakage was
8/6/2014 18:28:46 header observed Manikandan 8/6/2014 18:10:00 Rectified Ganesh Medium Ganesh
8/6/2014 22:57:06 Dosing vessel-01 Air line valve passing is observed Ritu 8/6/2014 22:10:00 Checked found ok. Ganesh/Hindo Hindo
Area differential pressure is out of
8/7/2014 13:59:07 Upstream area range (30 Pa) Ritu 8/7/2014 14:00:00 Completed. Hindo Medium Hindo
8/8/2014 17:32:02 Dosing vessel 01 Vessel lamp not working Ritu 8/8/2014 17:30:00 completed electrical team
Flush bottom diaphragm leak
8/9/2014 10:09:42 MEDIA VESSEL 01 observed Vishwanath 8/9/2014 10:10:00 Completed. Hindo Medium Hindo.
8/10/2014 9:46:20 Holding vessel 03 drain valve handle was broken Manikandan 8/10/2014 7:00:00 Completed. Hindo Medium Hindo.
Gear box oil seal broken and oil
8/13/2014 11:46:22 250 L fermenter came out during the batch Ritu 8/12/2014 12:20:00 Completed Ganesh/Hindo Medium Ganesh & Hindo
Leakage observed during sample
8/14/2014 11:21:40 250L fermenter valve sterilization Ritu 8/14/2014 11:21:00 Completed Ganesh Medium Ganesh
Upstream Area
8/14/2014 12:23:34 (Washing area) Lights are not working Ritu 8/14/2014 12:23:00 completed Electrical team electrical team
8/19/2014 16:19:40 250L fermenter sample valve leakage was observed Manikandan 8/19/2014 14:00:00 Completed Ganesh/Hindo medium Ganesh & Hindo
Lamps are not Lamps are not working in washing
8/20/2014 9:33:13 working area inside production plant Praveen Kumar 8/20/2014 9:30:00 completed Electrical team electrical team
8/21/2014 9:30:28 Liquid filling area Light is not glowing. Vishwanath 8/21/2014 9:30:00 Completed Electrical team electrical team
8/26/2014 9:12:07 FG area BPM/PD/RFG/01 is not working. Vishwanath 8/26/2014 9:00:00 completed Electrical team electrical team
Medial vessel 01 &
8/28/2014 12:38:07 02 Gaskets to be changed Ritu 8/28/2014 12:35:00 completed Ganesh.R
Upstream
documentation
9/3/2014 11:04:55 office Cupboard door to be fixed Ritu 9/3/2014 11:04:00 Completed Ganesh.R Medium Ganesh.R
9/4/2014 22:58:49 SCADA system mouse not working fine Manikandan 9/4/2014 22:25:00 Completed Electrical team Abhijith
Flush bottom valve leakage
9/8/2014 21:56:23 Media vessel 01 observed Ritu 9/8/2014 21:00:00 Completed Ganesh.R Medium Ganesh.R
5Kl fermenter jacket steam header Ganesh ,Lokesh &
9/9/2014 10:49:45 5KL Fermenter valve leak. Vishwanath 9/9/2014 10:01:00 Completed. Ganesh.R Medium Monesh
chilled water line leakage was
9/10/2014 9:47:40 Holding vessel 02 observed. Irfan 9/10/2014 9:25:00 Completed Ganesh.R Medium Ganesh.R
DO probe of 250L Main DO probe malfunctioning
9/14/2014 1:16:57 Fermenter (Showing wrong value) Sathish E 9/14/2014 1:14:00 completed instrumentataion team high instrumentataion team
9/15/2014 14:11:19 HLV-02 Vent valve diaphragm to be rectified Suresh 9/15/2014 14:10:00 Completed Ganesh & Monesh Medium Ganesh.R
Wall mounted glass
in Packing area is In downstream - Wall mounted glass
9/15/2014 22:19:04 broken. in Packing area is broken. Praveen Kumar 9/15/2014 22:18:00 broken glass removed, new glass fixed Hindo/Ganesh Medium
Butterfly valve next to drain line
leakage observed, when the vessel
9/17/2014 5:38:58 Harvest Vessel 01 is in pressure. Sathish E 9/17/2014 5:30:00 Rectified Hindo/Ganesh Medium Ganesh.R
5KL Fermenter- 5KL jacket steam inlet valve(AAPV)
9/22/2014 10:37:40 Fermenter area lekage observed. Rohini 9/15/2014 8:30:00 Completed Ganesh & Dinesh Medium Ganesh.R
Near 5KL fermenter ceiling light is
9/22/2014 20:48:02 Upstream not glowing Manikandan 9/22/2014 14:01:00 Completed yadav
9/22/2014 20:49:27 250L fermenter sample valve flow not coming Manikandan 9/22/2014 14:00:00 Completed Ganesh & Hindo Medium Ganesh & Hindo
250L fermenter - Standby DO probe (Bella made) is
9/23/2014 14:33:18 DO probe fluctuating. Sathish E 9/22/2014 14:00:00 Rectified and system under observation Sachin/Manju high
9/26/2014 4:42:38 Harvest vessel 02 Vessel lamp is not working Ritu 9/26/2014 4:42:00 replaced electrical team electrical team
Upstream exit door Door interlock from upstream to BPM
9/26/2014 4:47:26 interlock main corridor is broken. Ritu 9/26/2014 4:47:00 Rectified Ganesh Medium Ganesh.R
BPM/PD/CFG/01
(Continuous Ejection is not happening in CIP
9/26/2014 15:18:54 centrifuge) mode. Suresh 9/26/2014 15:00:00 Completed Chakravarty
Flush bottom(butterfly valve) and the
9/26/2014 15:21:20 Harvest vessel-02 valve next to that is passing. Suresh 9/26/2014 15:00:00 Rectified Ganesh/Hindo Medium Ganesh
Flush bottom valve leakage was
9/30/2014 13:10:44 Dosing vessel 01 observed. Manikandan 9/30/2014 8:10:00 Completed Hindo
9/30/2014 13:12:53 Upstream corridor ceiling light is not glowing Manikandan 9/30/2014 12:17:00 Completed electrical team electrical team Waiting for Ballasts
Thermosyphon steam trap leakage
10/2/2014 18:44:09 5KL fermenter observed Ritu 10/2/2014 16:45:00 completed Ganesh Medium Ganesh
Both main and standby DO probes
10/3/2014 15:33:34 250 L fermenter are not working Ritu 10/2/2014 15:00:00 completed sachin High instrumentation team
10/20/2014 11:18:18 5KL fermenter pin hole leak observed in drain line Manikandan 10/20/2014 10:10:00 Rectified Ganesh/hindo Medium Ganesh
10/24/2014 12:06:03 mobile vessel 03 pin hole leakage observed in jacket Manikandan 10/24/2014 10:15:00 Rectified Ganesh
10/28/2014 12:44:57 Liquid filling area tubelight is not glowing k.vinod kumar 10/28/2014 11:16:00 Completed Abhijith Electrical Team
continuous
centrifuge During cip ejection is not happening
10/31/2014 10:53:38 BPM/PD/CFG/01 in cip mode k.vinod kumar 10/31/2014 10:54:00 Completed Abhijith
Gents change
10/31/2014 10:55:01 room lights are not glowing k.vinod kumar 10/31/2014 10:55:00 Completed Abhijith
Flush bottom valve leakage
11/7/2014 15:18:56 5 KL fermenter observed Ritu 11/7/2014 15:15:00 Rectified Hindo Medium Hindo
5 KL fermenter
11/7/2014 15:21:05 thermosyphon Steam inlet valve damaged. Ritu 11/7/2014 15:20:00 Rectified Ganesh Medium Ganesh
11/9/2014 20:12:21 5000 L Fermenter Both DO sensors are not working Vishwanath 11/8/2014 15:00:00 completed instrumentation team high instrumentation team
11/9/2014 22:07:15 5000L Fermenter Sample valve problem. Vishwanath 11/9/2014 21:00:00 Rectified Ganesh Medium Ganesh
5KL fermenter Discussed with
transfer line praveen work has
diaphragm valve 5KL fermenter transfer line been completed by
11/22/2014 12:03:39 leakage observed diaphragm valve leakage observed. Praveen Kumar 11/21/2014 17:02:00 Completed Ganesh Medium Ganesh someone.
Ceiling lamp not Ceiling lamp not working in
working in downstream area inside
11/22/2014 12:05:23 downstream area chromatography area. Praveen Kumar 11/22/2014 11:32:00 Completed Abhijith
pH and pH and Conductivity probes are not
Conductivity working in pH and Conductivity Bought new make- Eutech. Working fine now. Earlier
probes are not meter, which are kept in upstream low conductivity range could not be measured. Now
11/22/2014 12:07:52 working. lab. Praveen Kumar 11/22/2014 12:01:00 working fine Manju/Sachin
pH probes are not
working in all pH probes are not working in all
11/22/2014 12:09:08 mobile vessels. mobile vessels. Praveen Kumar 11/22/2014 12:10:00 Completed Manju
 Name of the
Breakdown person raising the Contact person from Severity of the
Timestamp equipment/Area Give brief details of the issue request Date of reporting Current status of the issue Engineering problem Closed by Remarks
Lamp is not
working inside Lamp is not working inside holding
11/22/2014 12:10:51 holding vessel 03. vessel 03. Praveen Kumar 11/22/2014 12:10:00 Completed Abhijith
pH and conductivity
probes are not
working properly in pH and conductivity probes are not
chromatography working properly in chromatography
11/22/2014 12:12:25 skid. skid. Praveen Kumar 11/22/2014 12:14:00 calibration done Sachin/manju
Air line steam diaphragm valve
11/23/2014 9:37:02 Dosing vessel 02 passing Manikandan 11/23/2014 7:00:00 Rectified Ganesh Medium Ganesh & monesh
11/23/2014 13:46:41 Dosing vessel 01 Vessel lamp not glowing Manikandan 11/23/2014 13:40:00 Lamp changed
Changed
flush bottom valve leakage was diaphragm with
11/23/2014 13:49:05 250L fermenter observed Manikandan 11/23/2014 13:40:00 Completed. Hindo High Hindo. new GF diaphragm
11/27/2014 4:29:59 5KL fermenter Man hole lid gasket damaged Manikandan 11/27/2014 4:30:00 Completed. Ganesh
Vessel lamp is not
working in harvest Vessel lamp is not working in harvest
11/27/2014 4:45:01 vessel 02 vessel 02 Praveen kumar 11/27/2014 4:45:00 Completed. Abhijith Mounesh
two FRL's not
working,and
Pressure guage in changed pressure
FRL (3 no's) is not Pressure guage in FRL (3 no's) is guage for two
11/27/2014 4:47:27 working properly. not working properly. Praveen kumar 72867672.2 completed Sachin/Manju medium manjunath FRL's
Door closures to be
changed in
11/29/2014 Fermenter area Door closing action was not proper Satheesh 11/29/2014 14:01:00 Completed Dinesh Dinesh
Media vessel 01 &
11/29/2014 3:33:09 02 Hand hole lid gasket damaged Manikandan 11/29/2014 3:30:00 Completed Ganesh medium Ganesh
Air line diaphragm(drain) valve to be
11/29/2014 3:42:40 Media vessel 02 fix back Manikandan 11/29/2014 3:40:00 Completed. Hindo medium Hindo.
Sample line steam diaphragm valve
11/30/2014 2:44:07 5KL fermenter handle broken Manikandan 11/30/2014 2:40:00 Completed Ganesh medium Ganesh
Harvest vessel M.F
feed line to be Dinesh, Manju,
11/30/2014 21:07:02 assembled Line to be fixed Vinod 11/30/2014 10:27:00 Completed Dinesh High Lokanath & Abhijith
CIP Panel not
11/30/2014 21:08:18 Responding Panel not responding to touch. Manjunath 11/30/2014 16:30:00 Completed Abhijith Medium Abhijith
QC chemical
12/4/2014 11:05:53 instrumentation lab Ceiling light is not working debashree 12/4/2014 11:05:00 Completed Abhijith Mounesh, Lokesh
checked and found
that the
tempearture probe
Temperature probe attached with loose connection,
conductivity meter is not showing and found low
12/4/2014 11:09:23 Conductivity meter proper temperature. debashree 12/4/2014 11:07:00 Completed Ganesh medium Loganathan sensitivity of probe
QC chemical Plug point for pass box is not
12/4/2014 11:15:22 instrumentation lab working debashree 12/4/2014 11:15:00 Completed Electrical Team medium Electrical Team
Same was made
Ultra filtration ready and taken
12/7/2014 8:46:27 system HMI display not switching ON. Vishwanath 12/7/2014 7:00:00 Completed Instrumentation Team medium Instrumentation Team trial its found ok.
Pump is not taking the feed properly
Peristaltic pump and the rotary header is giving noise
12/8/2014 6:18:32 (2no's) while running. Suresh 12/8/2014 6:00:00 Completed
continuous During CIP ejection is not happening
12/9/2014 10:32:26 centrifuge in CIP mode Manikandan 12/9/2014 10:17:00 Completed Chakravarthy medium Ganesh.R
Media vessel 01 Baby boiler Steam line end TC
12/15/2014 5:47:36 back side leakage observed. Sathish E 12/15/2014 5:50:00 Completed Hindo medium Hindo
Top floor of 5KL fermenter, near to
emergency door, power socket not
12/15/2014 5:49:33 Fermentation Area working. Sathish E 12/15/2014 5:50:00 Completed Electrical team medium Electrical team
Thermosyphone steam inlet MDV
12/18/2014 7:23:30 250L Fermenter diaphragm leak observed Vishwanath 12/18/2014 7:23:00 Completed Hindo Medium Karthik/Ningappa
250 L header
12/19/2014 10:20:34 steam line. steam header line pin hole leakage. Vishwanath 12/18/2014 10:00:00 completed. Hindo medium Hindo
The bottom step in the 8ft ladder got
8ft ladder / BPM damaged and its shaking when we
1/14/2015 4:16:25 downstream climb on that. Suresh 1/14/2015 4:15:00 completed. Mathew Medium
Air line diaphragm valve handle was
1/16/2015 9:37:38 Media vessel 02 broken Manikandan 1/16/2015 9:30:00 Completed Ganesh.R Medium Ganesh.R
pure header steam line leakage was
observed near media vessel
1/16/2015 9:39:04 Pure steam line backside Manikandan 1/16/2015 9:35:00 Completed Ganesh.R
Upstream cleaning
1/16/2015 9:40:30 area wooden cupboard lock came out Manikandan 1/16/2015 9:35:00 Completed Murali Medium Murali
Sparger line MDV diaphragm
damaged. To be changed
1/16/2015 14:21:48 Media vessel 02 immediately. Ritu 1/16/2015 11:00:00 Completed Ganesh.R Medium Ganesh.R
1/16/2015 14:22:43 Media vessel 01 Jacket steam ON/OFF valve leakage Manikandan 1/16/2015 14:15:00 Completed Murali Medium Murali
Pressure transmitter and pressure
gauge reading is showing huge
1/16/2015 14:24:00 Media vessel 02 difference. Ritu 1/16/2015 14:20:00 completed manjunath Medium manjunath
Micro pipette 20-
1/20/2015 15:18:05 200 microliter Micro pipette is not working properly. debashree 1/20/2015 15:17:00 completed Sachin Medium
Computer system Mouse connected with the system is
1/29/2015 15:08:39 QC chemical not working properly debashree 1/29/2015 15:10:00 Completed, replaced with new mouse Murali Low Chennaveera
In approved Raw Material Stores &
Quarantine area, the lights are not
Tube Lights & ON.
Pestop machine In Raw Material Receipt area, the
2/3/2015 17:15:58 PESTOP machine is not working. Balamurugan 3/2/2015 17:15:00 PESTOP machine serviced and refixed Karthick Medium Karthick
Ceiling lamps are Ceiling lamps are not working in
2/5/2015 7:52:39 not working filling area, downstream. praveen kumar 5/2/2015 7:50:00 completed electrical team Medium electrical team
ICOM charger is
2/5/2015 7:53:28 not working. ICOM charger is not working. praveen kumar 2/5/2015 7:52:00 Working Fine Soundar Low Soundar
2/11/2015 7:37:20 Media vessel 01 Jacket steam ON/OFF valve leakage Manikandan 2/11/2015 7:15:00 completed Murali Medium
Jacket stream trap ON/OFF valve
2/11/2015 7:38:27 media vessel 01 leakage was observed Manikandan 2/11/2015 7:15:00 completed Murali Medium Murali
2/11/2015 7:39:18 CIP tank Alkali pump not working Manikandan 2/11/2015 7:18:00 completed Ganesh.R Medium
pure steam header heavy leakage
2/11/2015 7:40:32 pure steam header was observed behind media vessel Manikandan 2/11/2015 7:20:00 completed Murali Medium Murali
Pure steam header condensated leakage was observed
2/11/2015 7:41:31 line near 250L fermenter top. Manikandan 2/11/2015 7:20:00 completed Murali Medium Murali
2/11/2015 7:42:46 Upstream corridor clean room door handle came out Manikandan 2/11/2015 7:31:00 completed Murali Medium
2/11/2015 7:45:42 Dosing vessel 01 vessel lamp to be fix Manikandan 2/11/2015 7:35:00 completed Chakra
New steam header TC leakage was observed before
2/11/2015 7:47:19 line and after filter housing. Manikandan 2/11/2015 7:36:00 Completed Ganesh.R Medium 12/2/2015
New steam header line- Steam inlet
MDV valve to sample valve
diaphragm leakage
2/11/2015 7:49:14 5KL fermenter Manikandan 2/11/2015 7:35:00 Completed Ganesh.R Medium Ganesh.R
2/11/2015 7:50:03 250L fermenter motor guard to be fix back Manikandan 2/11/2015 7:38:00 Completed Ganesh.R Medium Ganesh.R
continuous chilled water header line to be fix
2/11/2015 7:53:48 centrifuge back Manikandan 2/11/2015 7:45:00 Completed Ganesh.R
Jacket ON/OFF Pneumatic tube
2/11/2015 7:56:09 Dosing vessel 02 parallel connector to be connect Manikandan 2/11/2015 7:52:00 Completed Murali Medium Murali
Upstream material
2/11/2015 8:58:59 dispensing area floor epoxy came out Manikandan 2/11/2015 9:00:00 Completed Ganesh.R Medium Ganesh.R
2/11/2015 21:44:38 250L fermenter Level sensor showing wrong valve Manikandan 2/11/2015 12:00:00 Completed Loganath&Sachin medium Ganesh.R
Temperature probe attached with
2/12/2015 9:29:52 Conductivity meter conductivity meter is not working Debashree 2/12/2015 9:30:00 Completed Soundar medium Soundar
Hot plate QC
2/13/2015 15:33:01 chemical Hot plate is not heating Debashree 2/13/2015 15:23:00 Completed chakra
blush bottom valve leakage was
2/18/2015 8:54:38 media vessel 01 observed Manikandan 2/18/2015 8:15:00 Completed. Replaced with new diaphragm Murali medium Murali
Media vessel-2
2/18/2015 12:17:34 (Upstream) Vessel steam trap valve leakage. Manikandan Completed Bhogeshwara
Pure steam header Steam trap leakage behind media
2/18/2015 12:18:45 (Upstream) vessel-2 Manikandan 2/18/2015 0:18:00 Completed Murali medium Murali
Upstream CIP inlet line diaphragm
valve leakage was observed behind
2/18/2015 13:07:20 CIP line harvesting vessel 01 Manikandan 2/18/2015 12:15:00 Completed Murali medium
 Name of the
Breakdown person raising the Contact person from Severity of the
Timestamp equipment/Area Give brief details of the issue request Date of reporting Current status of the issue Engineering problem Closed by Remarks
Downstream chilled water header line valve
2/18/2015 13:16:46 activation area leakage was observed. Manikandan 2/18/2015 12:50:00 Completed Murali medium Murali
Diaphragm valve in
water loop in house
keeping area is not
working (next to Diaphragm valve in water loop in
documentation house keeping area is not working
2/21/2015 8:49:13 room) (next to documentation room) praveen kumar 2/10/22015 8:50:00 Rectified Ganesh.R medium Ganesh
spray ball inside
holding vessel 03 is spray ball inside holding vessel 03 is
2/21/2015 8:51:23 displaced displaced praveen kumar 2/21/2015 8:50:00 Rectified Murali medium Mounesh
2/22/2015 6:16:55 250 L Fermentor DPT fluctuation Manikandan 2/22/2015 6:00:00 Rectified murugan Medium murugan
Blush bottom valve steam inlet
2/22/2015 6:17:49 Media vessel 01 diaphragm valve passing Manikandan 2/22/2015 6:02:00 Rectified Replaced with new diaphragm Murali medium Murali
2/25/2015 4:56:39 Media vessel 02 Jacket drain valve leakage Manikandan 2/25/2015 5:00:00 Completed Murali medium
sample valve steam inlet diaphragm
2/25/2015 4:58:16 5KL fermenter valve leakage Manikandan 2/25/2015 5:00:00 Completed Ganesh.R Medium Ganesh
Flush bottom valve steam inlet
diaphragm valve leakage was
2/27/2015 22:06:09 5KL fermenter observed Manikandan 2/27/2015 22:00:00 Completed Murali Medium Murali
BPM Stores -
Approved raw
3/10/2015 17:04:34 material Area Ceiling Lights not working. Balamurugan 3/9/2015 17:00:00 Completed Electrical Team Karthik/Nigappa
BPM stores
3/10/2015 17:06:26 (Quarantine Area) Ceiling Lights is not working Balamurugan 3/10/2015 17:02:00 Completed Electrical Team
Concentration area
3/23/2015 18:09:38 (Downstream) Ceiling light not working. Suresh 3/23/2015 18:07:00 Completed Electrical Team
3/24/2015 16:19:00 Dossing vessel-01 Flush bottom valve MDV is passing Rohini 3/6/2015 15:00:00 Completed Murali &bhogeshwara Medium
TC clamp Leakage observed on the
3/24/2015 16:22:15 Media transfer line line Rohini 3/12/2015 6:00:00 Completed Bhogeshwara Medium
Steam trap passing in condensate
3/24/2015 16:29:18 5KL fermenter drain line fron transfer lines Rohini 3/7/2015 9:00:00 Completed Bhogeshwara Medium
3/24/2015 16:33:18 Dossing veesel-02 Top lid gasket is leakage observed Rohini 3/24/2015 16:30:00 Completed Bhogeshwara/Dinesh High
Near 250L fermenter pure steam
Pure steam header header line pin leakage was
4/9/2015 17:37:41 line observed Manikandan 4/9/2015 17:38:00 Completed Manju/bhogeshwar Medium
vessel lamp not there and pls
4/9/2015 17:39:08 Dosing vessel 01 arrange Manikandan 4/9/2015 17:38:00 Completed chakra
Rain Water leakage through
ventilation hole in Consumable
Consumable Stores.
4/22/2015 14:26:01 Stores Kindly take the necessary action. Balamurugan 4/22/2015 14:30:00 Completed sangram
Steam ON/OFF valve leakage was Bhogesh,Dinesh,
4/25/2015 4:08:07 250L fermenter observed near Plate heat exchanger Manikandan 4/25/2015 4:08:00 Completed Sarvana
Production
Lyophylizer / BPM Production lyophylizer compressor
5/9/2015 18:30:15 Downstream got trip during the process. Suresh 5/9/2015 18:30:00 Completed Electrical Team Medium
Vacuum pump oil entered inside the
R&D Lyophylizer / condensor chamber while stopping
5/9/2015 18:33:28 BPM Downstream the system. Suresh 5/9/2015 18:33:00 Completed Dinesh/Bhogesh Medium
Steam line support rusted and
5/11/2015 9:38:47 CIP room painting to be done Manikandan 5/11/2015 9:38:00 Completed Bhogeshwara/Dinesh Medium
Material
5/11/2015 9:42:04 Dispensing area Floor epoxy paint damaged Manikandan 5/11/2015 9:41:00 Completed Sayeed/bhogeshwara Medium
BPM Raw material
Dispensing booth
6/9/2015 6:03:23 area. Door interlock in malfunctioning. Suresh 6/9/2015 6:03:00 Completed Chakra Medium chakra
6/10/2015 17:22:38 BPM Stores In that trolley platform is rusted. balamurugan 6/10/2015 5:25:00 Completed Bhogeshwara/Dinesh Medium
In Quarantine area, The 250 kgs
6/10/2015 17:23:51 BPM Stores Weighing Balance Platform is rusted. Balamurugan 6/10/2015 5:27:00 Completed Bhogeshwara/Dinesh Medium Dinesh
BPM Liquid
filling/Packing area Temperature is out of range in liquid
6/23/2015 16:00:18 AHU filling/packing area. C.Suresh 6/23/2015 16:00:00 Completd Bhogesh and Dinesh Medium Dinesh
Consumable The Main Door of Consumable
7/30/2015 17:40:34 Stores Stores is not locking properly. Balamurugan.T 7/30/2015 5:40:00 Completd Dinesh
8/3/2015 5:54:33 5KL Fermenter sample valve leakage was observed Manikandan 8/3/2015 5:55:00 Completed Dinesh Medium Dinesh
8/3/2015 5:56:33 Dosing vessel 01 view glass leakage was observed Manikandan 8/3/2015 5:56:00 Completed Bhogeshwara Medium
8/3/2015 5:57:49 Upstream area MDV handles to be fixed Manikandan 8/3/2015 5:56:00 fixed Bhogeshwara/Sarvan Low Sarvan
CIP tank circulation pump leakage
Completed
8/3/2015 23:16:31 CIP system was observed Manikandan 8/3/2015 23:15:00 Dinesh and Chakravarty High Dinesh
Manual diaphragm valve(upstream
diversion line) leakage was observed
8/3/2015 23:18:13 CIP line behind harvesting tank 01. Manikandan 8/3/2015 23:15:00 Completed Bhogesh and Dinesh Medium
Exhaust control valve flange leakage
8/25/2015 12:32:33 5KL fermenter was observed Manikandan 8/25/2015 12:30:00 Completed Bhogeshwara/Sarvan Medium
Exhaust bypass valve leakage was
8/25/2015 12:35:32 5KL fermenter observed Manikandan 8/25/2015 12:30:00 Completed Bhogeshwara Medium
BPM STORES 750 grm Weighing Balance is not
(DISPENSING working. Some error came.
9/1/2015 11:15:37 BOOTH) Pl do the needful. Balamurugan T 9/1/2015 11:15:00 Completed Murugan Medium
Dosing vessel 01 Top dish gasket leakage was
9/8/2015 4:29:47 and 02 observed Manikandan 9/8/2015 4:30:00 Completed Dinesh and Chakravarty High
flush bottom valve leakage was
9/8/2015 4:30:57 Media vessel 01 observed Manikandan 9/8/2015 4:30:00 Completed Dinesn and Bhogesh Medium
All 15mm diaphragm valves leakage Bhogesh,Dinesh,
9/8/2015 4:31:58 Dosing vessel 02 was observed Suresh 9/8/2015 4:30:00 Completed Sarvana Medium Saravana
Jacket drain vale (ON/OFF) leakage
9/8/2015 4:32:47 Media vessel 01 was observed Manikandan 9/8/2015 4:31:00 completed chakravarthy Medium chakravarthy
Jacket steam line pin hole leakage Chakravarthy and
9/8/2015 4:33:43 Media vessels was observed Manikandan 9/8/2015 4:31:00 Completed Murugan Medium
Pure steam diaphragm valve handle
9/8/2015 4:34:37 250L fermenter to be fixed Manikandan 9/8/2015 4:33:00 fixed Bhogesh Medium Bogesh
Antifoam line diaphragm valve
9/8/2015 4:35:38 5Kl fermenter leakage was observed Manikandan 9/8/2015 4:35:00 Completed Dinesh Medium Dinesh
9/8/2015 4:38:15 Dosing vessel 02 Light glass flange leakage Manikandan 9/8/2015 4:38:00 Completed Bhogesh and Dinesh Medium Dinesh
BPM FG area
-20 deep freezer
9/9/2015 3:11:33 (BPM/PD/DFZ/02) Bio matrix access not working. Suresh 9/9/2015 3:11:00 Completed Arun/sayeed
flush bottom valve (ADV 50mm)
9/23/2015 15:02:58 5KL Fermenter leakage was observed Manikandan 9/23/2015 15:00:00 Completed Dinesh Medium Dinesh
9/23/2015 15:15:09 5KL fermenter Air line flow control valve passing Manikandan 9/23/2015 15:10:00 Completed Dinesh
Flush bottom valve leakage was
9/30/2015 10:36:00 Dosing vessel 01 observed Manikandan 9/30/2015 6:01:00 Completed Dinesh Medium Dinesh
In upstream filter
steam header near media vessels1 & 2, near 250 l,
3/13/2016 15:49:09 having more leaks, near steam filter. Rajendiran 2/28/2016 9:00:00 Replaced gaskets Dinesh Medium Dinesh
In upstream filter
steam header near media vessels1 & 2, near 250 l,
3/13/2016 15:50:27 having more leaks, near steam filter. Rajendiran 2/28/2016 9:00:00 Replaced gaskets Dinesh Medium Dinesh
3/14/2016 9:58:00 cip pump leakage observed vinod kumar 3/14/2016 9:57:00 Completed Dinesh Medium
one tube light not
3/14/2016 10:00:48 glowing upstream lab vinod kumar 3/14/2016 10:00:00 Completed Chakra/Mathew Low Chakra
top of 250l fermentor 2 tubelights are Above PLC Panel Light replaced - Above 250
3/14/2016 10:02:22 upstream area not glowing vinod kumar 3/14/2016 10:02:00 Fermenter light to be replaced Chakra/Mathew Low Chakra
upstream area washing room wash
wash basin drain basin drain line leakage and water
3/14/2016 10:04:47 line leakage coming outside sathish 3/14/2016 10:04:00 Rectified Dinesh Low Dinesh
upstream housekeeping area door
3/14/2016 10:06:58 Door handle inside handle not there sathish 3/14/2016 10:06:00 Rectified Chakra Low Chakra
valve handle not dosing vessel 01 drain line valve
3/14/2016 10:09:24 there handle not there vinod kumar 3/14/2016 10:09:00 Handle fixed chakra Medium chakra
dosing vessel 02 drain line valve not
3/14/2016 10:11:14 valve to be fixed there to be fixed vinod kumar 3/14/2016 10:11:00 fixed Bogesh Low Bogesh
jacket drain line pin Media vessel 01 jacket drain line pin
3/14/2016 10:13:04 hole leakage hole leakage to be arrested sathish 3/14/2016 10:13:00 completed chakra medium chakra
near flush bottom valve cip leakage
3/14/2016 10:14:23 cip tank observed vinod kumar 3/14/2016 10:14:00 Rectified
upstream near dosing vessel 02 two
tube lights not tube lights ,near media vessel 01 two
glowing in tube lights,above scada four tube Near Media Vessel 01 - Light replaced,
3/14/2016 10:16:43 upstream lights not working vinod kumar 3/14/2016 10:16:00 SCADA/Dosing Vessel Need scaffolding Chakra/ Mathew Low
 Name of the
Breakdown person raising the Contact person from Severity of the
Timestamp equipment/Area Give brief details of the issue request Date of reporting Current status of the issue Engineering problem Closed by Remarks
cell separation area
3/14/2016 10:18:10 door problem door is not closing vinod kumar 3/14/2016 10:18:00 Rectified Saravanan Low Saravanan
tube lights not
glowing in cell 3 tubelights not glowing inside cell
3/14/2016 10:19:51 separation area separation area sathish 3/14/2016 10:19:00 completed chakra low chakra
tube light not Near cip preparation area door
3/14/2016 10:21:05 glowing corridor one tubelight not glowing sathish 3/14/2016 10:21:00 Completed Chakra/Mathew Low Chakra
downstream washing area door not
3/14/2016 10:22:24 door is not closing working properly vinod kumar 3/14/2016 10:22:00 Completed Chakra/Mathew Low Chakra
downstream cleaned utensils area
Tubelight not both the tubelights are not glowing
3/14/2016 10:24:03 glowing area looks dark vinod kumar 3/14/2016 10:23:00 Completed Chakra/Mathew Low Chakra
near chromatography area one tube
light not glowing,washing area two
tube lights,column packing area one
tube light,packing area two tube Chomatography area - Completed , Wash Area -
lights,near passbox one tube light, Completed, Packking Area - Completed, Cooridor near
concentration area one tube light, Packing Area - Completed,
downstream tube near packing area door two
3/14/2016 10:28:20 lights not glowing tubelights, vinod kumar 3/14/2016 10:28:00 Chakra/Mathew Low Chakra
concentration area one door is not
3/14/2016 10:29:24 door is not opening opening to be rectified vinod kumar 3/14/2016 10:29:00 Rectified Chakra/Mathew Low Chakra
Holding vessel 01 next to flush
valve not bottom valve drain line valve not
3/14/2016 10:30:44 functioning functioning vinod kumar 3/14/2016 10:30:00 Rectified Bogesh Medium Bogesh
chromatography
system bubble trap actuated valve not
3/14/2016 10:32:21 downstream working vinod kumar 3/14/2016 10:31:00 completed Murugan Medium Mrugan
Liquid filling area Area Temperature and humidity out
3/14/2016 10:34:27 downstream of range vinod kumar 3/14/2016 10:34:00 AHU- 04 DX unit compressor failure
dosing vessel 02, Near agitator shaft leakage observed
3/14/2016 13:24:39 upstream ammonia smell is coming heavily vinod kumar 3/14/2016 13:24:00 leak check done , no leak observed chakra medium chakra
"BPM FG area
-20 deep freezer
3/15/2016 4:08:40 (BPM/PD/DFZ/02)" Bio matrix access not working. Suresh.C 3/15/2016 4:08:00 Completed Chakra medium Chakra
Upstream - CIP CIP skid circulation pump seal
3/15/2016 4:12:13 area leakage. Suresh.C 3/15/2016 4:12:00 Replaced mechanical seal and O rings Dinesh/Mathew High Dinesh
Downstream - In the double door, one of the door
3/15/2016 4:17:51 Concentration area lock(on top) cannot be released. Suresh.C 3/15/2016 4:17:00 Rectified Chakra/Mathew Low Chakra
Most of the diaphragm valves
3/15/2016 4:20:07 Upstream area doesn't have handle to operate. Suresh.C 3/15/2016 4:20:00 Awaiting for material Dinesha Low
Downstream - In one of the 400mm dia
Chromatography Chromatography column, top
3/15/2016 4:22:48 column adopter O-ring leakage observed. Suresh.C 3/15/2016 4:22:00 completed chakra low
Chilled water inlet and outlet line
Downstream leakage ,near the SS hose
3/15/2016 4:35:41 Activation Area connector. Manjunath 3/15/2016 4:35:00 rectified Chakra Low
Chromatography In Chromatography system both inlet
Area: and outlet pH and conductivity meter
Chromatography not showing correct value,to be In process of procuring conductivity solution, pH
3/15/2016 4:41:02 System calibrated. Manjunath 3/15/2016 4:41:00 sensor will be calibrated ASAP Anand Med
in media vessel 1&2 vessel light
media vessel 1&2 cable & valve air tube contact with
instrument air tube steam line its already 75% damaged
& light electrical before full damage rectify it as soon
3/16/2016 13:11:03 cable damage as RAJENDIRAN 3/16/2016 12:30:00 rectified chakra med chakra
in both peristaltic pumps silicon tube
locks was damaged , to be replaced
3/16/2016 13:28:33 peristaltic pump with new locks RAJENDIRAN 3/16/2016 13:30:00 Rectified Dinesh Low Dinesh
in 5 kl fermenter, vessel pressure
gauge ,exhaust filter housing
pressure gauge,vessel PT, vessel
TT. all are not matching during
sterilization, so we dont know which
one is working correctly .calibrate all
to get actual temperature & Will be calibrated as per schedule, but will cross
3/16/2016 13:38:20 5kl fermenter pressure. RAJENDIRAN 3/16/2016 13:35:00 together once Anand Low
exhaust control valve will open in
40% only ,due to this we have to
open bypass while reach maximum
air flow . and while power trip time
we are getting more trouble. so
calibrate the control valve . Functional but to evaluate properly together. Please
3/16/2016 13:52:08 5KL FERMENTER RAJENDIRAN 3/16/2016 13:50:00 advice on date and time
Pin hole leakage observed in Found no leak , Spot not identified.If found leak
3/19/2016 3:37:55 MF system permeate line. Sathish E 3/19/2016 3:40:00 welding to be done Chakra Medium chakra
starting problem ,VFD tip due to
amps variation,if VFD reach more
3/20/2016 20:08:52 centrifuge then 60 amps it will going to trip, RAJENDIRAN 3/20/2016 20:08:00 rectified chakra low chakra
25 MM dummy used for Ph was not
removed because it was jammed, Do not use that port till it is rectified. permanent
3/20/2016 20:14:39 5KL FERMENTER (near sample port), RAJENDIRAN 3/20/2016 20:15:00 rectification will take some time
Air flowmeter(Rotameter) is
functioning but not showing any
Upstream- 250L airflow reading (eg. 125LPM)in
3/22/2016 5:47:57 fermenter SCADA. Suresh.C 3/22/2016 5:47:00 completed anand R medium anand
BPM/PD/DFZ/02
-20 DEGREE
quarantine deep
3/24/2016 19:46:42 freezer Finger access is not working k.vinod kumar 3/24/2016 19:46:00 completed sayeed medium Syeeed
Heavy leakage observed near Jacket
drain valve, Mseal which was used
to arrest the leakage (few months
3/24/2016 23:41:51 Media vessel 01 before) came off now. Sathish E 3/24/2016 23:40:00 completed chakra/dinesh high chakra/dinesh
Agitator - oil spills observed, Need to
3/24/2016 23:47:06 5kl fermenter be check for its level. Sathish E 3/24/2016 23:46:00 oil seal replaced found no leak , oil level checked ok chakra/dinesh high dinesh
Agitator - Motor guard to be fixed
3/24/2016 23:48:28 5kl fermenter back Sathish E 3/24/2016 23:48:00 fixed bogesh low bogesh
Upstream. 250L
fermenter and
3/26/2016 21:23:51 Media vessel-02 Vessel lamp not glowing. Suresh.C 3/26/2016 21:23:00 rectified chakra medium chakra
Upstream- Media Vessel bottom transfer line isolation
3/26/2016 21:26:04 vessel-01 valve diaphragm leakage. Suresh.C 3/26/2016 21:25:00 completed
Continuous centrifuge chilled water
inlet line has to be made permanent
Cell separation (currently water/process hose is
3/26/2016 21:34:53 area. used) Suresh.C 3/25/2016 21:34:00 completed chakra medium chakra
Neat to flush bottom valve,in glycerol
media vessel 1, transferring line,if valve open fully
3/27/2016 12:56:00 upstream heavy leakage observed k.vinod kumar 3/27/2016 12:55:00 completed
Downstream- The top adopter O rings changed
Chromatography with new one and again the pressure changed but leakage observed ordered new set of O
3/28/2016 19:18:29 column. test is failing. Suresh.C 3/28/2016 19:18:00 rings yet to recive
5KL jacket outlet temperature
Upstream - 5KL transmitter (TE-301) is showing 0.0
3/28/2016 19:20:46 fermenter value in the SCADA. Suresh.C 3/28/2016 19:20:00 Completed Anand/Murugan Low Anand
Holding vessel -03, Agitator stopped suddenly during
3/29/2016 12:44:12 Concentration area activation k.vinod kumar 3/29/2016 12:44:00 Completed murugan medium murugan
UV
Spectrophotometer
4/2/2016 9:59:25 -QC Chemical D2 Lamp is not glowing Stella 4/2/2016 9:58:00 completed chakra high chakra
250l FIC 401 is continuously alarming to
4/4/2016 17:24:12 fermentor/upstream be rectified ASAP k.vinod kumar 4/4/2016 17:23:00 Completed anand medium anand
250L and 5KL
fermenter/Upstrea
4/4/2016 17:25:40 m Vessel temperature increased. Manimaran 4/4/2016 17:25:00 Issue rectified. Temp came back to normal
Media vessel
4/4/2016 17:26:41 02/Upstream Vessel lamp not glowing Manimaran 4/4/2016 17:26:00 rectified chakra medium chakra
Peristaltic Ravel peristaltic pump which arrived
4/4/2016 17:28:12 pump/Upstream newly not working. Manimaran 4/4/2016 17:27:00 rectified chakra Medium
CIP transferring pump leakage
4/4/2016 17:32:49 PUMP/CIP area observed again after replacing pump vinod kumar 4/4/2016 17:32:00 serviced and fixed back leakage to be checked
 Name of the
Breakdown person raising the Contact person from Severity of the
Timestamp equipment/Area Give brief details of the issue request Date of reporting Current status of the issue Engineering problem Closed by Remarks
Media vessel Media vessel 02, Jacket drain ball
4/4/2016 17:34:58 02/Upstream valve leakage observed. Manimaran 4/4/2016 17:34:00 completed
Jacket temperature transmitter(TE-
301) not working. Due to that
Upstream-5KL temperature auto control not
4/5/2016 0:01:53 fermenter working. Suresh.C 4/5/2016 0:01:00 new sensor fixed under observation anand medium anand
Exhaust PID valve is not opening
properly. Due to that vessel back
4/5/2016 0:03:35 Upstream - 5KL pressure increasing. Suresh.C 4/5/2016 0:03:00 Repeated
Cell separation During startup of centrifuge, VFD trip Running the centrifuge after idle period, this issue may
area - Continuous alarm is raised and the system is be faced. Once the desired rpm is reached the
4/5/2016 0:17:01 centrifuge. getting stopped. Suresh.C 4/5/2016 0:16:00 centrifuge will run normally.
Steam Line - TC clamp in steam line above
Electrical boiler line dossing vessel, condensate is
- Near Dossing leaking heavily. TC clamp gasket
4/8/2016 9:29:20 vessel needs to be changed. Sathish E 4/8/2016 9:30:00 Completed Murugan medium
One of the Peristaltic pump (Watson
4/10/2016 9:23:54 Peristaltic pump Marlow make) is not working. Suresh.C 4/10/2016 9:23:00 Alternate pumps provided . chakra Medium chakra
harvest vessel 02, centrifuge sup collection inlet valve
4/11/2016 5:00:10 centrifuge area in harvest vessel 02 handle broken k.vinod kumar 4/11/2016 4:59:00 handle fixed chakra medium chakra
Cell separation MF permeate transfer line diaphragm
4/12/2016 7:42:06 area. valve passing. Suresh.C 4/12/2016 7:41:00 Valve replaced chakra medium chakra
5 KL FERMENTER jacket steam inlet valve(AAPV-306)
jacket steam inlet is passing due to this while cooling
4/21/2016 19:50:23 valve(AAPV-306) chilled water mixing with steam RAJENDIRAN 4/19/2016 17:20:00 Completed
Chiller inlet header line to reflux
4/28/2016 7:02:14 5KL fermenter cooler - leakage observed Sathish E 4/28/2016 7:00:00 completed team medium team
Cell seperation Hydraulic door closure hinge came
4/28/2016 7:05:40 area door off. To be fixed back. Sathish E 4/28/2016 7:00:00 completed chakra/pramod Low chakra
4/28/2016 7:06:27 Dosing vessel 01 Vessel lamp not working Sathish E 4/28/2016 7:06:00 completed chakra Low chakra
25mm port - pH probe infit got stuck
4/28/2016 7:08:42 5KL fermenter - need to be removed after this batch Sathish E 4/28/2016 7:08:00 Removed chakra Low chakra
Bubble trap top valve - L bend
Chromatography connector leakage observed during
4/28/2016 7:11:31 System opening of valve, to be changed Sathish E 4/28/2016 7:11:00 REctified murugan Low
pH probe holder heavy leakage
observed - infit O rings need to be
4/28/2016 7:25:56 Mobile vessel 03 replaced with new one Sathish E 4/28/2016 7:25:00 completed chakra/Anand medium chakra/anand
Sample valve (1/2 inch valve) -
Harvest vessel 01 handle is very loosely operational,
4/28/2016 7:30:48 &02 any time it may come off Sathish E 4/28/2016 7:30:00 completed chakra/Anand medium chakra/anand
Upstream Lab
4/28/2016 7:32:16 Pass box UV lamp is not glowing in pass box Sathish E 4/28/2016 7:32:00 completed chakra Low chakra
Instrument air leakage sound
4/28/2016 7:33:55 Media vessel panel observed in the solenoid valve Sathish E 4/28/2016 7:33:00 rectified anand low anand
Instrument air leakage sound
4/28/2016 7:34:01 Media vessel panel observed in the solenoid valve Sathish E 4/28/2016 7:33:00 rectified anand low anand
In fermentation area - Behind media
vessel, media vessel jacket drain
line, electrical boiler line stem inlet
4/28/2016 7:37:10 Steam header line valve to 5kl Sathish E 4/28/2016 7:36:00 completed chakra/matew medium chakra
Air line bypass valve and diprod
valve handles too tight to operate,
4/28/2016 7:39:37 Media vessel 02 need to replace with new handles Sathish E 4/28/2016 7:39:00 Completed
Finished goods
4/28/2016 7:43:16 area -80 deep freezer temperature raising Sathish E 4/28/2016 7:43:00 Rectified
Chilling outlet (SS hose) leakage
4/28/2016 7:48:44 Activation room observed Sathish E 4/28/2016 7:48:00 Hose replaced Murrugan/Chakra Medium Murrugan/Chakra
Quality Control -
Chemical

Air Conditioner Air Conditioner is not working for Rajeshwari

4/28/2016 12:40:31 past 3 days. Please do the needful. Govindarajan 4/28/2016 12:39:00 rectified chakra medium chakra/mathew
Electrical boiler line - TC clamp
4/30/2016 14:05:12 Fermentation area leakage observed sa rectified murugan low murugan
Upstream - Dosing
5/10/2016 20:31:08 vessel-01 Vessel lamp not glowing. Suresh.C 5/10/2016 20:30:00 rectified Murrugan/Chakra Medium Murrugan/Chakra
Emergency shower
- QC chemical
5/20/2016 10:31:58 departmentt Water leakage from the shower Stella 5/20/2016 10:30:00 Rectified Dinesh/ Pramod low
Hose connected to sink in washing
5/20/2016 10:34:50 QC washing area area is leaking Stella 5/20/2016 10:33:00 completed chakra Low chakra
Lights were out from Friday night
Downstream Area onwards. All Emergency line lights
5/23/2016 6:25:30 and Rest rooms not glowing. Sathish E 5/23/2016 6:25:00 Rectified Murrugan/Chakra Medium Murrugan/Chakra
Steam inlet PU tube leakage
5/23/2016 6:27:40 CIP Tank observed Sathish E 5/23/2016 6:27:00 completed Veeresh/ Pramod Low veeresh/ pramod
Media vessel In steam header line pin hole leak
5/23/2016 6:32:05 steam header line observed. Sathish E 5/23/2016 6:32:00 completed chakra/ pramod Low Chakra/pramod
Bubble Trap Vent valve (Top valve)
Chromatography L bend PU tube connector leakage
6/1/2016 2:15:01 System observed which has to be changed. Sathish E 6/1/2016 2:14:00 completed Murugan Low Murugan
From the system, PU tube air
Chromatography leakage observed. Has to be
6/1/2016 2:16:16 System rectified Sathish E 6/1/2016 2:16:00 Completed murugan medium murugan
Vessel Support's were directly
contacting the vessel, Gaskets
needs to be placed in between to
6/1/2016 2:18:27 5KL Fermenter avoid dent on vessel. Sathish E 6/1/2016 2:18:00 gaskets provided
Drain Valve and Steam Trap valve,
both were passing. Ammonia
drained in this batch, needs to be
6/1/2016 2:21:54 Dossing Vessel 01 fixed before next batch. Sathish E 6/1/2016 2:21:00 Completed chakra Meium chakra
Near 5KL adjacent to air line,
6/1/2016 2:23:27 Fermentation Area junction box not working. Sathish E 6/1/2016 2:23:00 Completed chakra Low chakra
Upstream - Steam steam header line (next to filter)
6/6/2016 6:42:07 line header. manual valve not closing properly Anandh 6/5/2016 9:41:00 Completed {Applied grease now ok} BHOGESH/PRAMOD Low Bogesh/Pramod
Steam inlet valve (AAPV 305) to
Plate heat exchanger, leakage
6/12/2016 20:38:45 250L fermenter observed Sathish E 6/12/2016 20:38:00 completed mrugan Low Mrugan
Pressure Gauge in Airline filter
housing, Vessel top dish and
Exhaust line filter housing were not
6/12/2016 20:40:24 250L Fermenter working. Sathish E 6/12/2016 20:40:00 completed
CIP tank motor leakage not arrested.
While transferring more leakage
6/12/2016 20:41:56 CIP tank observed. Sathish E 6/12/2016 20:41:00 completed Dinesh Medium Dinesh
6/17/2016 3:13:46 KILL TANK KILL TANK TT IS NOT WORKING Rajendiran 6/17/2016 3:13:00 completed Murugan/Veeresh Medium Murugam/Veeresh
Back side of 250L fermenter leakage
of TC Clamp from steam condensate
6/22/2016 13:47:10 250L Fermenter line observed Sathish E 6/22/2016 13:47:00 completed Murugan/Veeresh Low Murugam/Veeresh
Sample valve cotter pin damaged.
Now valve handle is not there, to be
7/2/2016 23:55:14 5KL fermenter replaced before next batch. Simang 7/2/2016 23:51:00 replaced with new valve
Leakage observed from the Line
7/2/2016 23:59:13 Media Vessel 01 Isolation manual diaphragm valve. Simang 7/2/2016 23:59:00 completed
Steam Header Line leakage
7/7/2016 13:58:16 Media Vessel observed Simang 7/7/2016 13:58:00 completed
Agitator sound is different at higher
7/7/2016 13:59:40 Holding Vessel 03 rpm. Simang 7/7/2016 13:59:00 Rectified under observation
At 2500 LPM, exhaust PID valve is
5KL fermenter - opened 100% & vessel pressure
7/9/2016 22:20:32 PID valve maintained 0.65 to 0.70 bar only. Manimaran.S 7/9/2016 22:01:00 Not a problem
HPLC in QC There is a leaking in through the
7/27/2016 23:45:23 BPM/QC/CHR/01 pump. John Wesley 7/27/2016 23:30:00 Rectified
8/10/2016 9:22:17 QC Chemical AC AC not working Fameeda 8/10/2016 9:22:00 Completed Medium
8/29/2016 10:05:55 AC in QC chemical AC not working Jhon wesely 8/29/2016 10:05:00 completed
AC not working at QC chemical
9/6/2016 12:03:10 AC Department Sendil 9/6/2016 12:02:00 Completed
BPM/PD/DFZ/01 / Approved -20 degree deep freezer
finished goods temperature is not maintaining in the
9/22/2016 6:09:09 storage area range. vinod 9/22/2016 6:09:00 Rectified and is fine now
 Name of the
Breakdown person raising the Contact person from Severity of the
Timestamp equipment/Area Give brief details of the issue request Date of reporting Current status of the issue Engineering problem Closed by Remarks
PLC false alarm continuously coming
9/23/2016 6:17:18 Upstream in night shift Manimaran 9/23/2016 6:15:00 Acknowledged
Documentation
room door,
documentation Door closing and opening lock
10/5/2016 22:45:58 room broken,door is in open condition. k.vinod kumar 5/10/2016 22:45:00 Rectified Dinesh/Pramod
Door is hitting with huge sound while
close.
10/5/2016 22:47:25 Door,Upstream lab k.vinod kumar 10/5/2016 22:47:00 Replaced
Door,upstream
cleaned utensils Door opening and closing unit
10/5/2016 22:49:05 area. removed need to be fixed k.vinod kumar 10/5/2016 22:49:00 replaced the unit Dinesh/Pramod
Formulation main Bio metric not working in Formulation
10/6/2016 10:28:36 door main door kishore 6/10/2016 10:28:00 Rectified
Gents primary
10/8/2016 2:35:17 change room Push plate need to be fixed Manimaran 10/8/2016 2:35:00 Fixed
chromatography
system
(BPM/PD/CHR/01) Inlet ph and outlet ph is not showing
/chromatography correct values,inlet conductivity is
10/8/2016 3:44:35 area not showing correct value vinod kumar 10/8/2016 3:44:00 Rectified
Holding vessel holding vessel temperature is
10/8/2016 3:46:18 01/activation area showing out of range value vinod kumar 10/8/2016 3:46:00 Rectified Murugan/Anand Medium Murugan/Anand
Dosing vessel 01
and 02/Upstream
10/8/2016 3:47:30 area vessel lamp is not glowing vinod kumar 10/8/2016 3:47:00 completed Murugan/Veeresh Low Murugan/Veeresh
Flush bottom valve leakage
11/1/2016 15:00:06 Media vessel 01 observed Sivanesh 11/1/2016 15:00:00 Completed BHOGESH/DINESH
Condensate leakage observed in
11/1/2016 15:03:28 CIP Area steam line to PHE Sathish E 11/1/2016 15:00:00 completed
purified water
distribution loop purified water distribution loop valve
11/10/2016 12:34:10 valve passing passing in upstream washing area k.vinod kumar 11/10/2016 12:34:00 Completed BHOGESH/DINESH
DO probe malfunction in last two
11/17/2016 1:50:37 250L Fermenter seed fermentation Sathish E 11/17/2016 1:50:00 Rectified Anand/ Murugan High Anand/ Murugan
Portable water flow
11/17/2016 1:52:41 meter Display is not showing Nagoor 11/17/2016 1:52:00 Working now Veera/Anand
Temperature probe fluctuating,
during process. To be Calibrated
11/17/2016 1:54:10 5KL fermenter after the batch. Sathish E 11/17/2016 1:54:00 Calibration cross checked and found ok Chakravarthy High Chakravarthy/Murugan
Impellar came off from shaft and Chakravarthy/Murugan / Chakravarthy/Murugan
11/17/2016 1:55:26 Mobile Vessel 04 lying inside the vessel. Nagoor 11/17/2016 1:55:00 Fixed Veera Medium / Veera
In emergency door Hydraulic door
Downstream closer came off. Screw to be
11/17/2016 1:58:21 Emergency door replaced. Nagoor 11/17/2016 1:58:00 Completed Pramod Low Pramod/Veera
Ravel peristaltic One of the Ravel made peristaltic
11/17/2016 2:02:03 pump pump is not working Nagoor 11/17/2016 2:02:00 found no issues with the pump Anand Low Anand
in cip system ,PHC steam inlet valve
12/1/2016 9:31:05 CIP SYSTEM leak RAJENDIRAN 12/1/2016 6:51:00 Arrested BHOGESH/DINESH Medium BHOGESH/DINESH
QC-Chemical ( Wet Out of two lighting, one is not
lab Area) working in the QC-Chemical ( Wet
12/7/2016 14:10:23 lab Area) Sendil Kumar 12/7/2016 14:10:00 completed Chakravarthy Low Murugan
BPM Production
12/9/2016 8:53:12 office. Office A/C not working. C.Suresh 12/9/2016 8:53:00 Completed Chakravarthy Low Chakravarthy
One of the light to be changed. Not
12/10/2016 13:39:02 CIP room glowing. Sathish 12/12/2016 13:40:00 completed Chakravarthy Low Veeresh
Sample valve drain valve leakage
12/10/2016 15:02:01 5KL fermenter observed s completed Bogesh Bogesh
Sample valve drain valve leakage
12/10/2016 15:03:06 5KL fermenter observed. Siva 12/10/2016 15:00:00 completed Bogesh HIgh Bogesh
Media vessel jacket
inlet pneumatic
valve AAPV-03 not Found instrument air is not coming in
12/11/2016 17:54:27 working. the respective air line. S.Nagoor 12/11/2016 18:01:00 completed Murugan HIgh Murugan/Veeresh
From CIP tank
transfer pump while CIP tank transfer pump running
12/11/2016 18:00:36 leakage found leakage observed from the pump S.Nagoor 12/11/2016 18:01:00 completed Dinesh
12/12/2016 8:26:50 5kl fermenter one DO probe malfunction Sathish E 12/12/2016 8:25:00 Rectified under observation Murugan/Anand HIgh
Media vessel-2 jacket outlet
pneumaticvalve AAPV-02 is not
working.
Media vessel-2 found instrument air is not coming for
12/12/2016 12:58:11 BPM/PD/FMV/02 the respective air line. S.Nagoor 12/12/2016 12:55:00 Completed Murugan HIgh Murugan/Veeresh
Media vessel-2 Air sparger and bypass manual valve
12/12/2016 13:01:02 BPM/PD/FMV/02 inlet to Media vessel-2 is leaking Amit 12/12/2016 13:00:00 Completed Bogesh medium
500 kg capacity weighing balance is
12/20/2016 14:26:20 Formulation plant not working kishore 12/20/2016 14:26:00 Completed Anand Medium Anand
During calibration of pH meter -
Standard buffer values ( 4.01/7.
00/10.1 ) are different from actual The model of the meter values are predifined. No
values obtained in measurement issues with the values in Cal mode .Vendor also
mode . conformed the same . Closed
12/22/2016 9:29:28 pH meter Sendil 12/22/2016 9:26:00 Murugan Medium Murugan
Conductivity meter is not functioning
12/22/2016 9:30:34 Conductivity meter properly in QC-chemical lab Sendil Kumar 12/22/2016 9:30:00 new sensor fixed workig fine Anand Medium Anand/ Veeresh
DO probe of 5000 DO probe 104 not responding during
12/26/2016 12:13:28 L fermenter fermentation Amit 12/26/2016 12:12:00 rectified Anand
12/30/2016 15:08:42 250L fermenter Steam header valve passing. Rajendiran 12/30/2016 15:10:00 Completed valve replaced Bhogesh
Water inlet PU tube connector
12/30/2016 15:10:05 Centrifuge leakage observed Sathish E 12/30/2016 15:11:00 Completed Veeresh
1/5/2017 12:40:52 QC-Chemical AHU not working in the Wet lab area Sendil Kumar 1/5/2017 12:40:00 Completed Chakra
Shaker Incubator
(BPM/MB/SHR/01&
02) & Autoclave Electric power has been getting trip
(BPM/MB/AUT/02)- frequently for above mentioned
1/5/2017 16:33:07 Microbiology Lab equipments. sathish kumar.R 1/5/2017 16:33:00 Completed Chakra Medium Chakra/Veeresh
In current batch UPS/TRYP/16/028,
Upstream : 5KL pH in SCADA and QC there is a All three meters ph will be calibrated based on the
1/6/2017 9:50:35 fermenter difference of 0.35. Suresh.C 1/6/2017 9:50:00 result single point to be done in 5 KL.Closed Chakra
Upstream: Media
1/6/2017 10:03:06 vessel-2 Vessel lamp not working Suresh.C 1/6/2017 10:03:00 Rectified Veeresh Low Veeresh
Air inlet before filter housing
1/8/2017 3:37:33 250L Fermenter (ADV405) valve passing observed. Sathish E 1/8/2017 3:37:00 Rectified Chakra
DO PROBS BOTH ARE NOT
1/9/2017 19:26:47 5 KL FERMENTER RESPONDING RAJENDIRAN 1/9/2017 15:00:00 Done Single point calibration for 45%..It is working fine Anand High Anand/Murrugan
Steam line leakage observed from Medium
1/16/2017 8:47:46 250L fermenter the TC clamp Sathish E 1/16/2017 8:50:00 Rectified Chakra Chakra
Glass panel in the door to wash area Medium
1/16/2017 8:48:49 Downstream broken Sathish E 1/16/2017 8:50:00 Completed Dinesh Dinesha
Flush bottom valve and line isolation
1/16/2017 8:50:24 Media vessel 02 valve to 5KL valve leakage observed Sathish E 1/16/2017 8:50:00 Rectified . Cross will be done after this batch Murugan High Murugan
1/16/2017 8:52:54 Dosing vessel 01 Agitator Shaft leakage manikandan 1/16/2017 8:50:00 fixed Dinesh
Blind flange fixed temporarily for to use.Agitator
1/18/2017 20:16:26 Dosing vessel 2 M.Seal heavy leak observed Manimaran 1/18/2017 20:15:00 assembly will be fixed ASAP Dinesh and Murugan High
1/22/2017 9:25:23 Dosing vessel 01 Temperature sensor not working. S.Nagoor 1/22/2017 9:20:00 Rectified... Replaced with new sensor.. Veeresh / Murugan High Anand/Murrugan
BOD Incubator-I
(BPM/MB/BDI/01), Electric power supply does not Medium
1/23/2017 15:04:47 Microbiology Lab coming on sathish kumar.R 1/23/2017 15:05:00 Rectified Veeresh Veeresh
1/25/2017 4:08:52 CIP tank Cip tank level sensor is not working k.vinod kumar 1/25/2017 4:08:00 Rectified Murugan Medium Murugan
Deep freezer 02/ Need finger access for keeping the
finished goods area quarantine materials inside deep
1/25/2017 5:28:35 freezer after completion of batch. k.vinod kumar 1/25/2017 5:28:00 rectified Sayeed Low
Ammonia cylinder connection brasso
1/28/2017 6:02:09 250l/upstream area bolt is in broken condition. k.vinod kumar 1/28/2017 6:02:00 Completed SS coller fixed Dinesh Medium Dinesh
Cip alkali dosing In cip tank alkali dosing pump is not
1/28/2017 6:03:41 pump working. k.vinod kumar 1/28/2017 6:03:00 Completed Dinesha Medium Dinesh
Table top pH meter
1/30/2017 9:02:20 - Production Calibration cannot be done Sathish E Completed Murugan Medium Murugan
Not getting calibrated - Showing
Table top pH meter wrong values for fresh standard
1/30/2017 9:04:01 - Production buffer Sathish E 1/30/2017 9:10:00 Completed Murugan Medium Murugan
 Name of the
Breakdown person raising the Contact person from Severity of the
Timestamp equipment/Area Give brief details of the issue request Date of reporting Current status of the issue Engineering problem Closed by Remarks
HMI is not working.(UPS to be
2/1/2017 17:50:20 Upstream CIP skid replaced) Suresh.C 2/1/2017 17:50:00 Completed Veeresh High veeresh
QC Chemical
production pass
2/2/2017 14:14:06 box No power Supply fameeda 2/2/2017 14:14:00 Completed Chakra Low
QC Chemical entry
2/2/2017 14:15:07 air curtain Not working Fameeda 2/2/2017 14:15:00 Completed Dinesh and Bhogesh Medium Dinesh
Computer connected with Aglient
spectropjotometer is not working
2/2/2017 14:16:32 Computer properly Fameeda 2/2/2017 14:16:00 Completed Murugan Low
2/4/2017 6:13:36 Diaphragm pump Pump leaking heavily Manimaran 2/4/2017 3:00:00 Completed Dinesha Medium Dinesh
All the microbiology room
temperature is out of limit ( Limit of
Temperature: 22°C ± 3°C),but now
temp is 27 °C-30°C.

Microbiology Lab Note:All the microbiology equipment

2/7/2017 11:57:59 AHU temp is within the limit. sathish kumar.R 2/7/2017 11:57:00 Completed Dinesh Medium Dinesh
Passbox of
destruction The passbox gives shock when
2/14/2017 10:55:50 autoclave area touched when the switch is on Amar 2/14/2017 10:55:00 completed Chakra Medium Chakra
The pressure gauge shows less than
15psi and less than 121 degrees
even though the set pressure is 15
Destruction psi and 121 degrees. The
autoclave pressure temperature and pressure are not
2/14/2017 10:58:34 gauge reaching the set limits. Amar 2/14/2017 11:00:00 completed Chakra low
BOTTOM FLUSH VALVE can't able
to close passing heavy ,
NEXT TO BOTTOM VALVE
(transfer line diversion valve) from
valve stem heavy leak. FYI BEFORE
2/22/2017 4:02:09 MEDIA VESSEL 1 START UP THIS BATCH PM DONE. RAJENDIRAN 2/22/2017 4:00:00 rectified Dinesh Medium Dinesh
Media vessel Jacket water outlet there is a pinhole
2/23/2017 20:02:40 1/Upstream leakage k.vinod kumar 2/23/2017 20:02:00 rectified veeresh
jacket cooling outlet line pin holes
2/24/2017 5:29:46 media vessel 1 heavy leak RAJENDIRAN 2/24/2017 1:00:00 rectified veeresh
UPS tripped twice yesterday (one for
10mins & next for about 20mins).
During this time process kept in
Fermentation manual mode without SCADA
3/5/2017 11:45:34 Room operations. Anand 3/5/2017 11:45:00 Rectified Chakra high Sayeed
Media vessel back side of MV02 steam header
3/5/2017 11:46:16 Steam header leakage observed. Anand 3/5/2017 11:45:00 rectified Bogesh/pramod
3/6/2017 9:19:45 AC at QC chemical Not working Fameeda 3/6/2017 9:18:00 rectified chakra low
Thermostat
connected to
Agilent UV
3/7/2017 10:16:39 Spectrophotometer Temperature is not maintaining Fameeda 3/7/2017 10:16:00 rectified veeresh medium
H&N formulation
Blend Room No. 2 | gasket leakage and top lid lock
3/7/2017 13:03:05 REZ/PD/PDB/02 problem kishore 3/7/2017 13:00:00 rectified irsad/pramod Low
3/15/2017 9:30:26 5KL fermenter One DO probe not working Manimaran 3/15/2017 9:30:00 rectified Karthick high
PUW loop valve cant be closed
completely. Stem problem identified.
3/16/2017 21:12:39 Activation Room As of now dummy kept. Krishna 3/16/2017 21:10:00 Completed Bhogesh Medium
Controller buttons are not in good
3/19/2017 18:04:59 Lyophylizer condition to operate. C.Suresh 3/19/2017 18:04:00 rectified sayeed
Dossing vessel 01
and 02 at upstream
fermentation area viewing lamp not working please
3/22/2017 7:06:45 BPM make it ready Anandh 3/22/2017 7:05:00 Completed Veeresh Low Veeresh
CFL not glowing at
downstream
column packing
3/22/2017 7:18:19 area CFL not glowing pls make it ready Anandh 3/22/2017 7:15:00 Completed Veeresh Low Veeresh
Harvest Vessel 02
at BPM
3/22/2017 7:20:09 centrifugation Area agitator not running pls make it ready Anandh 3/22/2017 7:20:00 Rectified Murugan Medium Murugan
BPM/PB/08-
3/23/2017 8:34:22 Downstream Passbox UV lamp is not Gloving. S.Nagoor 3/23/2017 8:35:00 Completed Veeresh Medium Veeresh
Upstream
Fermentation area
& Cell separation Differential Pressure Gauge showing
3/23/2017 10:55:29 area 0.0 Pascals. S.Nagoor 3/23/2017 10:55:00 Cooling trial under progress sayeed
Media transfer line - Steam inlet
3/24/2017 17:35:51 5KL fermenter (pneumatic) valve to be fixed back Sathish E 3/24/2017 17:35:00 completed Bhogeshh Medium
MEDIA VESSEL
-02 Jacket steam inlet valve passing
jacket steam inlet (AAPV-01). give high severity for this
3/28/2017 5:05:08 AAPV-01 problem & rectify ASAP RAJENDIRAN 3/28/2017 4:00:00 Completed [Manual fixed] Veeresh Medium Veeresh
Mseal leakage found please rectify
3/30/2017 8:00:59 Dossing vessel 02 as soon as possible Anandh 3/30/2017 8:05:00 rectified
Pass box at QC RM,Production,micro pass box no
3/30/2017 12:27:44 chemical power supply Fameeda 3/30/2017 12:28:00 Completed Chakra Medium Completed
Ammonia gas cylinder regulator not
4/1/2017 9:28:08 250L Fermenter working Manimaran 4/1/2017 9:25:00 recieved new regulator
4/1/2017 9:29:17 250L Fermenter Air inler PID valve not working Manimaran 4/1/2017 9:30:00 Completed
Upstream area
4/1/2017 12:23:40 Pass box (11) UV lamp not glowing Nagoor 4/1/2017 12:25:00 completed
Cell separation Temperature and Relative humidity
4/2/2017 17:00:56 area (THM-06) Hygrometer is not working. S.Nagoor 4/2/2017 17:00:00 Completed Bhogesh
pH and DO Probe not working -
found that power supply to the
transmitter is not there - tempera
vary connection given by mr.
4/4/2017 4:39:37 250 L Fermenter veeresh Karthik 5/4/2017 1:30:00 Completed Karthik
BOD Incubator Cooling is not working.Temperature
(BPM/MB/BDI/01) is more than set value(Set Temp is R SATHISH
4/4/2017 18:02:53 /Microbiology Lab 32.5°C but it is displaying 34.9°C ) KUMAR 4/4/2017 18:00:00 completed Karthik Medium Karthik
Hand hole lid - one side welding is
4/6/2017 0:33:41 Mobile Vessel 04 off, lid is hanging now Sivanesh 4/6/2017 0:33:00 Completed Bhogeh
UV lamp not glowing in Upstream
area, Lyophilizer room, Packing
4/6/2017 0:40:29 Pass Box area, QC and Stores pass box's Sivanesh 4/6/2017 0:40:00 rectified Murugan/Rajesh Medium Murugan/Rajesh
Stores area -
4/6/2017 6:15:11 Airlock room Inter lock malfunction Sivanesh 4/6/2017 6:15:00 Completed Karthick
cip tank during circulation leak observed in
4/6/2017 6:19:01 heat exchanger Sivanesh 4/6/2017 6:20:00 Completed leak check pending
pneumatic valve (ADV 405) passage
4/6/2017 6:21:34 250 L Fermenter observed in air line Mukesh 4/6/2017 6:22:00 completed
Upstream-
Electrical boiler Electrical boiler filter housing
filter housing pressure gauge damaged. To be
4/7/2017 12:13:18 pressure gauge. replaced. C.Suresh 4/7/2017 12:13:00 Completed Karthick/Bhogesh
Upstream- Steam
main header filter Diesel boiler - Steam main header
housing pressure filter housing pressure gauge not
4/7/2017 12:18:16 gauge. working. C.Suresh 4/7/2017 12:18:00 Completed Karthick/Bhogesh
Destruction autoclave naturally gives
lots of unpleasant smell. QA and QC
chem area gets suffocated with
unpleasant smell during performing
destruction autoclave. The vent in
the destruction autoclave area has to
Destruction checked and rectified if any issues
4/11/2017 10:39:54 autoclave area vent present. Amar 4/11/2017 10:39:00 Vent is working fine sayeed
QC- Instrument
area and media
4/25/2017 18:01:27 disposal area CFL bulb not working Arun 4/25/2017 18:01:00 rectified Murugan/Rajesh
PERISTALTIC NEED SERVICING OF
4/26/2017 17:49:49 PUMP PERISTALTIC PUMPS AMIT 3/26/2017 17:40:00 closed
 Name of the
Breakdown person raising the Contact person from Severity of the
Timestamp equipment/Area Give brief details of the issue request Date of reporting Current status of the issue Engineering problem Closed by Remarks
INSUMENT AIR FRL DISPLAY
5/18/2017 17:06:43 CHROM SYSTEM BROKEN SIVANESH P 5/18/2017 16:01:00 Fixed new one Murugan Medium Murugan
outlet PH and conductivity is not
5/19/2017 14:11:00 Chrome system working Sivanesh 5/19/2017 2:30:00 Calibrated both,working fine Karthik/Murugan High Karthik/Murugan
some paticals observed inside the
5/19/2017 14:23:12 chrome system BT. Sivanesh 5/19/2017 14:30:00 Cleaned Karthik/Murugan
Chromotography
System Chromotography System Outlet pH
5/21/2017 22:05:56 (BPM/PD/CHR/01) Probe Damaged. S.Nagoor 5/21/2017 18:20:00 closed karthick
5/22/2017 9:27:47 QC chemical No cooling Fameeda 2/22/2017 9:27:00 completed chakra Medium chakra
AC at QC - AC at QC - Chemical is not working
5/25/2017 7:38:17 Chemical since 25-05-2017 - 5:00 AM SENDIL KUMAR S 5/25/2017 7:38:00 completed chakra Medium chakra
Refrigerator at QC- Refrigerator at QC- chemical is not
5/25/2017 7:39:59 chemical working properly SENDIL KUMAR S 5/25/2017 3:09:00 completed Chakra Medium
Qc chemical lab -
weighing balance Qc chemical lab - weighing balance
5/25/2017 10:16:11 it's not working. it's not working. Sarath.m 5/25/2017 10:14:00 closed karthick Medium
Entry to dispensing That door sensor not working
area from upstream properly, the magnetic door locker is
5/26/2017 15:09:27 air lock room Door. getting lock but sensor not working. S.Nagoor 5/26/2107 15:00:00 Rectified Chakra
Area temperature not in range.
5/26/2017 15:13:07 Lyophilizer Area Current temperature 28°C. S.Nagoor 5/26/2017 15:02:00 completed chakra chakra
Downstream area Drain points got
Downstream- choked due to this while cleaning Found lot of materials choked in the line cleared ,
5/26/2017 15:29:40 Production time water overflowing in the area. S.Nagoor 5/26/2017 15:10:00 instructed not put materials in the drain Anand SN Anand SN
Upstream area
5/26/2017 15:31:10 Poss box UV lamp not glowing in the poss box S.Nagoor 5/26/2017 15:12:00 Rectified Murugan Murugan
upstream area
small boiler steam near old 250 L Small boiler steam
5/29/2017 15:53:44 header line header line got leaking Karthik N 5/29/2017 15:50:00 Rectified Bogesh / chakra Bogesh / chakra
Air regulator (FRL) During process operation one of the
leakage found pls air regulator leakage found pls rectify
rectify the issue at this issue informed and handover to
5/30/2017 12:10:15 BPM upstream mr. Karthik engineering Anandh 5/1/2017 12:05:00 new regulator hand over to vinoth production Murugan Murugan
During process (at the time of power
BPM/PD/FMV/01 trip and compressor trip) we found
air inlet regulator that vessel pressure getting reduce
not functioning due to air regulator not functioning
properly (media properly. Informed to engineering
5/30/2017 12:21:21 vessel 01) team at the time of process. Anandh 5/30/2017 12:15:00 rectified karthik/Murugan karthik/Murugan
AC At QC
5/31/2017 9:44:53 Chemical lab Water dripping problem Fameeda 5/31/2017 9:43:00 Rectified Dinesha JS
HOLDING
VESSEL 01 / Holding vessel 01 lamp is not
6/1/2017 7:26:53 DOWNSTREAM working / urgent requirement Karthik N 6/1/2017 7:30:00 Completed veeresh
Near UF system
chilled water outlet During process we found UF system
loop not working chilled water its not functioning
properly at BPM properly. We found circulation not
6/3/2017 14:25:29 downstream area happening in that loop. Karthik 6/3/2017 14:15:00 Completed irshad
One Ravel peristaltic pump is not
6/3/2017 15:20:35 Upstream working. Anand 6/3/2017 15:20:00 closed karthik karthik
Steam Line Behind media vessel and top of new
Leakage in 250L fermenter 2 steam leakage
6/3/2017 15:28:31 Upstream observed. Anand 6/3/2017 15:30:00 completed irshad/bhogesh
Micro Filtration
System MF retentate PID valve
6/21/2017 6:52:19 (BPM/PD/MFS/01) malfunctioning. S.Nagoor 6/21/2017 6:50:00 Rectified karthik/Murugan karthik/Murugan
Media Vessel-01
6/21/2017 6:56:14 (BPM/PD/MDV/01) Vessel lamp not gloving. S.Nagoor 6/21/2017 6:51:00 Completed Murugan
Holding Vessel-01
6/21/2017 6:57:26 (BPM/PD/HLV/01) Vessel lamp is not gloving. S.Nagoor 6/21/2017 6:51:00 Completed murugan
Continuous
Centrifuge Broth and supernatant line Lamps
6/21/2017 7:01:28 (BPM/PD/CFG/01) not gloving. S.Nagoor 6/21/2017 7:00:00 Completed Murugan
CIP Tank
6/21/2017 7:08:22 (BPM/PD/CIP/01) Vessel lamp not gloving. S.Nagoor 6/21/2017 7:06:00 Rectified Murugan Murugan
Purified water loop
(PUW-01)
6/21/2017 7:17:58 Upstream. Water flow from this loop is very low. S.Nagoor 6/21/2017 7:15:00 Rectified Dinesha JS Dinesha JS
Purified Water loop
(PUW-16) Near by
6/21/2017 7:21:49 CIP Tank. Water flow from this loop is very low. S.Nagoor 6/21/2017 7:21:00 Rectified Dinesha JS Dinesha JS
Purified Water
Loop (PUW-11)
Downstream-
Column packing In this Purified Water loop Water flow
6/21/2017 7:49:52 area. is very low. S.Nagoor 6/21/2017 7:45:00 Rectified Dinesha JS
Harvesting Vessel
-01 Vessel Bottom Sample valve
6/21/2017 7:56:07 (BPM/PD/HRV/01) handwheel came out. S.Nagoor 6/21/2017 7:55:00 Rectified Dinesha JS Medium Dinesha JS
Water is stagnating between the
Upstream- Near by glass window.
6/21/2017 8:04:20 Staircase Window. S.Nagoor 6/21/2017 8:00:00 Cleaned Murugan/Pramod
In Upstream 5kl
vessel to Centifuge near "T" joint diaphragm valve carter
6/21/2017 8:10:58 transfer line. pin came out. S.Nagoor 6/21/2017 8:10:00 Rectified Dinesha JS medium Dinesha JS
5kl
BPM/PD/FER/03
Transfer line
perfusion line 1006
and mdv 1005 Transfer line perfusion line 1006 and
valve passing mdv 1005 valve passing found
found during during process, pls rectify the issues
6/27/2017 23:49:28 process. Informed to engineering Anandh 6/27/2017 23:50:00 Completed Dinesh/Bhogesh
QC-Chemical-
Instrumentation AC is not working as it is not
6/28/2017 10:54:51 area maintaining temperature. AHAMAD.DM 6/28/2017 10:54:00 rectified chakra
QC-Chemical-
Instrumentation
area & Media CFL bulbs to be replaced since
6/28/2017 11:01:02 disposal area lifetime of the bulbs got over (3 No.s) AHAMAD.DM 6/28/2017 11:00:00 rectified Murugan/Rajesh
Downstream
change room Locks needs to be fixed and rusting
7/5/2017 3:49:55 cupboard to be removed. vinod kumar 7/5/2017 3:49:00 fixed
7/5/2017 3:51:04 Downstream area AHU -02 /RG-01 grill to be cleaned k.vinod kumar 5/7/2017 3:50:00 Cleaned Bhogesh
1.Wall edges broken need to be
painted
2.AHU return grill fully rusted ,to be
changed
Downstream 3.Instrument air ss line fully rusted.
column packing 4.Purified water line hanging holders
7/5/2017 3:53:57 area fully rusted k.vinod kumar 5/7/2017 3:50:00 painting completed Irshad/Dinesh/Bhogesh
Packing Area
1.Door is not working properly.
2.AHU-04/RG-07,08 both the grills
Downstream fully rusted to be painted or to be
7/5/2017 3:55:59 changed. k.vinod kumar 5/7/2017 3:51:00 painting completed Irshad/Dinesh/Bhogesh
Downstream All Areas ceiling light boards to be
7/5/2017 3:56:55 cleaned k.vinod kumar 5/7/2017 3:51:00 completed murugan low murugan
Liquid filling area
1.Liquid filling machine LAF filter to
be cleaned
2.Entrance corner epoxy peeled off
7/5/2017 3:58:45 Downstream to be painted k.vinod kumar 5/7/2017 3:52:00 Completed Bhogesh
Harvesting vessel 01 pressure
7/5/2017 4:00:02 centrifuge area guage is malfunctioning k.vinod kumar 5/7/2017 3:52:00 Completed Murugan
Centrifuge to kill tank transfer line
Centrifuge Area above the harvest vessel 1 ,valve
7/5/2017 4:01:40 handle damaged to be changed k.vinod kumar 5/7/2017 3:53:00 Rectified Dinesh Low Dinesh
 Name of the
Breakdown person raising the Contact person from Severity of the
Timestamp equipment/Area Give brief details of the issue request Date of reporting Current status of the issue Engineering problem Closed by Remarks
Backside of harvest vessel
temporary chilled water line made to
centrifuge,it was broken, to be
7/5/2017 4:03:26 Harvest vessel 01 removed. k.vinod kumar 5/7/2017 3:52:00 Completed Bhogesh
centrifugation area Near Centrifuge chilled water return
7/5/2017 4:05:12 line insulation came out to be fixed. k.vinod kumar 5/7/2017 3:53:00 Completed Bhogesh
Caustic solution pumping to cip tank
CIP area hose is connected,permanent ss line
7/5/2017 4:19:30 to be fixed k.vinod kumar 5/7/2017 4:10:00 Completed Pramod
Microfiltration Permeate transfer line in MF pin hole
7/6/2017 3:58:50 BPM/PD/MFS/01 leak is there to be welded. k.vinod kumar 7/6/2017 3:58:00 Completed
Cip tank level sensor is
malfunctioning
7/6/2017 4:00:20 Cip tank k.vinod kumar 7/6/2017 3:58:00 Repeated karthik/Murugan
temparature and time sensor is not Karthick/Murugn/Veeres
7/15/2017 19:48:53 autoclave working sivanesh 7/15/2017 7:01:00 rectified h
chilling not happening properly jacket
7/15/2017 19:53:06 holding vessel 3 need to check sivanesh 7/15/2017 19:00:00 rectified Dinesh/Irshad medium Dinesh
downstream door is not working properly while
7/15/2017 20:05:57 (packing area) closing more sound observed sivanesh 7/15/2017 20:00:00 Completed Dinesh/Bhogesh
Pressure is not maintained in the
Magnehelic entire microbiology lab.The
guage/microbiology magnehelic guage shows less than 8
7/18/2017 13:00:28 lab pascals Mubeen mk 7/18/2017 13:00:00 Completed Bhogesh/Rajesh
Vessel view glass damaged in
Harvest vessel-02 and Holding
7/20/2017 12:16:20 Downstream vessel-01. C.Suresh 2/1/2017 12:15:00 Completed
Media vessel After filter steam inlet valve leakage
7/20/2017 13:46:48 01/upstream observed k.vinod kumar 7/20/2017 13:46:00 Completed Bhogesh/Dinesh
Near media vessel chill water header
Near Media vessel valves to be checked(if cooling water
7/20/2017 13:49:02 /upstream lined up mixing with chill water.) k.vinod kumar 7/20/2017 13:47:00 Rectified
Sample valve --before steam inlet
valve puncture observed to be
7/20/2017 13:50:16 5kl fermenter replaced. k.vinod kumar 7/20/2017 13:48:00 Completed Bhogesh/Dinesh Dinesh
Harvest vessel 02/ Bottom sample valve handle broken
7/20/2017 13:51:38 centrifuge area to be fixed. k.vinod kumar 7/20/2017 13:50:00 Replaced with new one Dinesha JS Low Dinesh
Scada room,
documentation
room,upstream
cleaning area,bpm
7/20/2017 13:53:12 office Cupboards doors broken to be fixed. k.vinod kumar 7/20/2017 13:51:00 Completed
Sample valve handle,sample steam
flushing valve handle is in ss bonet,it
is very hot to open the valve during
sampling,need to replace with
7/20/2017 13:55:56 5kl fermenter plastic. k.vinod kumar 7/20/2017 13:55:00 Changed with plastic handles Dinesh Low Dinesh
Sample valve handle,sample steam
flushing valve handle is in ss bonet,it
is very hot to open the valve during
sampling,need to replace with
7/20/2017 13:56:27 old 250l fermentor plastic. k.vinod kumar 7/20/2017 13:55:00 Changed with plastic handles Dinesh low Dinesh
Backside of media vessel 02 steam
leakage observed near header
7/20/2017 13:59:23 Media vessel 2 steam trap line. k.vinod kumar 7/20/2017 13:58:00 rectified
7/20/2017 17:52:26 Downstream Change room Mirror broken. C.Suresh 7/20/2017 17:52:00 rectified chakra low chakra
6 no's of Floor Drain traps not
7/20/2017 17:54:31 Downstream functioning properly. To be replaced. C.Suresh 7/20/2017 17:54:00 rectified Lokesh low Lokesh
Tap is under maintenance since1
H&N Formulation, month.
7/24/2017 17:23:40 Ladies washroom Fameeda 7/24/2017 17:23:00 Completed
Jacket steam trap and by-pass
chocked. During heat kill,
7/28/2017 5:53:53 Kill tank condensate is not getting drained. Suresh.C 7/28/2017 5:53:00 Rectified Dinesh low Dinesh
Holding vessel-3- Chilled water
7/28/2017 5:57:49 BPM downstream circulation is not happening. Suresh.C 7/28/2017 5:57:00 Rectified Dinesh low Dinesh
BPM upstream
fermentation area BPM upstream fermentation area
media vessel 01 media vessel 01 pressure gauge not
pressure gauge not working pls rectify actuall process
8/2/2017 23:46:07 working pressure is 2.2 bar but it shown 0 bar Anandh 8/2/2017 23:45:00 closed Karthik low Karthik
Downstream:
Packing & Filling
8/3/2017 9:27:48 room Door closure is not working properly. C.Suresh 8/3/2017 9:27:00 Replaced with new one Dinesh low Dinesh
AC temperature is not maintained, 1-
QC chemical - CFL light bulb is not working,
8/3/2017 13:57:34 instrument area cupboard door is not closing properly Arun 8/3/2017 13:57:00 completed Dinesh
H&N -
PRODUCTION
8/4/2017 10:19:29 AREA CEILING TUBE LIGHT kishore 8/4/2017 10:16:00 fixed rajesh & Pramod Dinesh
Sifter
(REZ/PD/SF/01)

8/10/2017 10:36:28 H&N - production Sifter problem in H&N - production kishore 8/10/2017 10:36:00 Completed Lokesh karthik/Murugan
Upstream
Documentation Karthick/Murugn/Veere
8/12/2017 7:38:11 Room Door lock came out to be fixed vinod kumar 8/12/2017 7:37:00 Completed Bhogesh/Irshad sh
QC INSTRUMENT AC is not working properly(room
9/5/2017 14:56:28 AREA temperature is not maintained) Bala 9/5/2017 14:54:00 Completed Bhogesh/Irshad Dinesh/Irshad
BPM downstream
wash area door
glass broken from During fumigation process door
one side. Pls glass was broken (while opening the
9/18/2017 0:43:30 change the glass. door) Anandh 9/17/2017 23:55:00 Completed Bhogesh/Irshad Dinesh/Bhogesh
centrifuge AOD BPM centrifugation area , centrifuge
pump not working AOD pump not working please
at upstream area, rectify the problem and hand over
9/25/2017 21:50:32 pls rectify ASAP. Anandh 9/25/2017 21:48:00 Completed Dinesh Bhogesh/Rajesh closed
QC Chemical
10/6/2017 11:51:08 Refrigerator Freezer door to be replaced Fameeda 10/6/2017 11:50:00 Completed irshad
BPM Downstream- Quatro flow diaphragm pump - VFD
Ultrafiltration frequency adjusting switch is not
11/16/2017 16:56:27 system functioning properly. Suresh.C 11/16/2017 16:56:00 Completed karthik closed
QC
INSTRUMENTATI AC is not working properly(room
11/17/2017 12:56:36 ON AREA temperature is not maintained) AHAMAD 11/17/2017 12:55:00 completed Chakra
BPM production 214 extension
11/20/2017 9:12:03 214 Extension cordless charger is not working. k.vinod kumar 11/20/2017 9:12:00 completed Karthik
AC in QC-Chemical
Instrumentation
11/20/2017 22:30:54 area AC IS NOT WORKING AHAMAD 11/20/2017 22:30:00 completed Chakra
Steam Condensate
leakage from
insulation in Steam Condensate leakage from
11/21/2017 11:19:58 Centrifuge area. insulation in Centrifuge area. vinod kumar 11/21/2017 11:19:00 Completed Dinesh
Microbiology lab temperature is not
maintaining, which is supposed to be
19-23 degree C. Presently it is
12/4/2017 9:36:15 Microbiology lab maintaining 26 degree C. Mubeen 12/4/2017 9:30:00 Rectified Dinesh
Door has not been get closed fully
Change Room-I itself since yesterday due to door
12/4/2017 14:47:18 Door closure issue Sathish Kumar 12/4/2017 14:50:00 Rectified Pramod
Column packing - AOD pump FRL dameged so that is
AO Diaphragm removed. New FRL to be fixed for
12/14/2017 6:28:12 pump the pump. S.Nagoor 12/14/2017 6:27:00 New FRL provided chakra
chromatography air sensor false alarm observed
12/30/2017 23:02:09 system continuously. need to be check sivanesh 12/31/2017 23:00:00 Rectified karthik
Near Ultra Filtration system Chilled
1/1/2018 7:22:53 Downstream water supply SS hose is leaking. S.Nagoor 1/1/2018 7:22:00 Rectified Dinesh
QC-INSTRUMENT
1/7/2018 0:05:17 AREA ceiling light not working arun 1/7/2018 0:04:00 New lamp fixed Chakra rajesh/pramod
1/8/2018 10:06:30 Mobile tank 05 Mobile tank -05 sample port leakage vinod kumar 1/8/2018 10:05:00 Rectified Chakra
 Name of the
Breakdown person raising the Contact person from Severity of the
Timestamp equipment/Area Give brief details of the issue request Date of reporting Current status of the issue Engineering problem Closed by Remarks
Mobile tank -02 Mobile tank-02 Jacket pinhole
1/8/2018 10:07:48 Downstream leakage vinod kumar 1/8/2018 10:05:00 Rectified Chakra
Near Chromatography system Chill
Downstream Area water outlet valve damaged to be
1/8/2018 10:09:12 Chill water line changed. vinod kumar 1/8/2018 10:05:00 Rectified Dinesh Dinesh
DOWNSTREAM /
1/10/2018 3:26:58 HLV 01 Vessel lamp is not working RAJENDIRAN 10/1/2018 3:26:00 emergency push button pressed now released. Chakra karthik
The incubation area room
temperature is going out of limit
(above 27 degrees) when the
shaker incubator is in running
Microbiology condition.The room temperature
1/10/2018 19:49:14 lab/Incubation area suppose to be 22 degrees(+-3). Mubeen 1/10/2018 19:45:00 Temp set point changed . temp is maintaining Chakra Chakra
Chromatography Chromatography System Air sensor
1/12/2018 14:24:50 System showing False alarm vinod kumar 1/12/2018 14:24:00 Working fine after calibration Chakra
CIP Tank Alkali In CIP tank Alkali Dosing pump is not
1/17/2018 1:45:27 dosing pump working. vinod kumar 1/17/2018 1:44:00 Rectified Dinesh Dinesh
QC- Chemical
Media disposal
1/21/2018 13:43:36 area Water tap is not closing properly arun 1/21/2018 13:43:00 Rectified chakra Irshad/Dinesh
QC-Chemical washbasin sink is not flushing
Chemical analysis properly, water logging inside
1/21/2018 13:53:23 area cupboard if its operated arun 1/21/2018 13:53:00 Rectified chakra
BDI 2 incubator ie
(22.5 degrees) in The incubator is not getting switched
1/22/2018 16:41:34 incubator room on. Amar 1/22/2018 16:30:00 Rectified Rajesh Rajesh
Shaker incubator 2
(BPM/MB/SHR/02) The shaker incubator is not
1/23/2018 14:44:36 in Cooling zone maintaining the set temperature Amar 1/23/2018 14:44:00 Found no issues , running trial taken ok . Rajesh Rajesh
Instrument panel - Instrument air
Upstream - leakages from the terminals are
1/25/2018 11:53:52 Instrument panel there in the panel. To be arrested. Suresh.C 1/25/2018 11:53:00 Arrested karthik
Electric cables for refrigerators
running on the floor with a junction
1/30/2018 15:43:41 BPM- FG area box. To be concealed over the walls. Suresh.C 1/30/2018 15:43:00 Completed Chakra
100MM glass
column 100mm galss column in downstream
2/3/2018 15:07:36 there is a leakage in oring. vinod kumar.k 2/3/2018 15:07:00 Rectfied Dinesh high Dinesh
upstream
fermentation area upstream fermentation area old 5kl
old 5kl valve no valve no APVV 302 physically
APVV 302 opened condition but in system
physically opened valves has been closed need to be
condition. All jacket rectified. All jacket utility lines
utility lines actuated actuated valves poly urothin tubes
valves poly urothin are become expired need to replace
tubes are become with new one (its breaking
2/16/2018 16:31:19 expired. automatically). jastikrishna 2/16/2018 16:25:00 Rectified Bogesh/karthik Dinesh
PESTOP UV light PESTOP which is above QC
3/7/2018 8:23:47 not working instrument area door, is not working arun 3/7/2018 8:20:00 Completed Pramod pramod
Temperature sensor painting peeled
3/10/2018 13:38:09 Mobile Vessel's off & sample valve leakage observed Vinu 3/10/2018 13:38:00 Completed Murugan /Veeresh Murugan/veeresh
MG-BPM -06 to MG-BPM-10 all Area
monitoring magnahelic guages
pressure is out of range need to be
3/11/2018 0:01:26 Downstream rectify ASAP. vinod kumar.k 3/11/2018 0:01:00 Rectified Dinesh Dinesh
Gents Toilet- BPM wash basin tap (left side) water
3/26/2018 22:32:06 Facility leaking. S.Nagoor 3/3/2018 22:30:00 Rectified Pramod
BPM/PD/HRV/02 -
3/27/2018 0:43:18 Harvest Vessel-02 Vessel lamp not glowing. S.Nagoor 3/3/2018 0:42:00 Rectified Rajesh Rajesh
Vessel jacket Drain valve (manual
BPM/PD/HRV/02 - pall valve) passing observed in
3/27/2018 0:51:39 Harvest vessel-02 closed condition. S.Nagoor 3/3/2018 0:50:00 Rectified Dinesh
Two Dosing pumps(Alkali & Acid)
were in removed condition, Need to
3/27/2018 0:58:26 CIP Tank be connect in working condition. S.Nagoor 3/27/2018 0:57:00 New AODD pump fixed Dinesh Dinesh
Downstream
3/27/2018 1:18:31 corrider One of ceiling lamp is not glowing. S.Nagoor 3/27/2018 1:10:00 Rectified Rajesh/pramod Rajesh/pramod
CIP preparation
3/27/2018 1:20:37 area One of ceiling lamp is not glowing. S.Nagoor 3/27/2018 1:20:00 Rectified Rajesh/pramod Rajesh/pramod
3/27/2018 1:21:55 Production Corridor One of ceiling lamp is not glowing. S.Nagoor 3/27/2018 1:21:00 Rectified Rajesh/pramod Rajesh/pramod
3/28/2018 1:07:13 CIP Tank Vessel lamp is not glowing. S.Nagoor 3/28/2018 1:06:00 fixed
QC-CHEMICAL Room-temperature in instrument
(instrument area), area is not maintained. QC chemical
3/30/2018 14:16:10 AC and intercom intercom is not working, line is dead. arun 3/30/2018 14:16:00 New exhaust fan fixed chakra chakra
Microbiology lab
temperature is not maintaining the
limit. The current
temperature is 28 degrees in all
rooms which suppose to be
3/30/2018 15:11:24 Microbiology Lab 22 degrees(+/- 3 ). Mubeen 3/30/2018 15:05:00 Rectified chakra chakra
Downstream
lyophilizer room Temperature and humidity out of
4/3/2018 15:30:13 and packing room. range. vinod kumar 4/3/2018 15:30:00 New Dx unit fixed , temp and Humidity in range chakra Chakra/Irshad
1.Inside Downstream area corridor
entrance light is not glowing.
2.Downstream washing area light is
4/3/2018 15:32:34 Downstream Area not glowing vinod kumar 4/3/2018 15:31:00 new lights fixed lokesh lokesh
DOWNSTREAM DOWNSTREAM inside corridor
4/9/2018 9:57:13 inside corridor. lights are not glowing. vinod kumar 4/9/2018 9:57:00 new lights fixed Murugan/lokesh Murugan/lokesh
The slide stage knob is not working
Microscope in properly as the band connecting is Sliding belt damage to be repleced with new , order to
4/13/2018 11:58:29 cooling zone. worn out and needs to be replaced. Amar 4/13/2018 11:57:00 be placed chakra
4/30/2018 9:19:24 Qc Chemical Area AC is not working Sarathkumar.m 4/30/2018 9:20:00 Rectified chakra Chakra
new refrigerator
5/22/2018 13:57:29 BPM/PD/RFG/03 refrigerator key got broken sivanesh 5/22/2018 2:50:00 New lock to be procured
Crevices and dents observed on
Packing area door.painting to be
5/29/2018 9:23:03 packing area done sivanesh 5/29/2018 9:22:00 Rectified Team Team
Rust to be removed on
Instrumentation lines present in
Packing area and Column packing
5/29/2018 9:25:00 packing area area sivanesh 5/29/2018 9:25:00 Rectified Team Team
Gap observed between light fixtures
5/29/2018 9:26:56 BPM and ceiling roof in BPM area sivanesh 5/29/2018 9:26:00 Rectified Team Team
All mobile vessels wheels are rusted
so badly need to paint or change the
5/29/2018 9:35:52 Downstream area same. manikandan 5/29/2018 9:35:00 Rectified Team Team
All electrical panels of mobile
5/29/2018 9:37:15 Downstream area vessels are rusted. manikandan 5/29/2018 9:36:00 Rectified Team Team
Rust observed on all doors in clean
5/29/2018 9:38:08 Downstream area room. Painting to be done. manikandan 5/29/2018 9:37:00 Rectified Team Team
Downstream filling Light fixture on top of the Lyophilizer
5/29/2018 9:39:08 area to be cleaned. manikandan 5/29/2018 9:38:00 Rectified Team Team
Downstram filling Wall cracks observed near view
5/29/2018 9:40:17 area panel of Lyophilizer area. manikandan 5/29/2018 9:39:00 Rectified Team Team
No calibration label and Instrument
Downstream ID on weighing balance
5/29/2018 9:42:03 weighing balance (BPM/PD/WGB/02) manikandan 5/29/2018 9:41:00 Rectified Team Team
Downstram filling Oil leakage & dust accumulation
5/29/2018 9:43:21 area observed backside of the Lyophilizer manikandan 5/29/2018 9:42:00 Rectified Team Team
Tool box to be placed in downstream
area, Found scattered tools
5/29/2018 9:44:14 Downstream area everywhere in area. manikandan 5/29/2018 9:43:00 Rectified Team Team
continous
6/8/2018 8:45:02 centrifuge CFG lamp is not glowing S.Nagoor 6/8/2018 8:45:00 New lamp fixed Team Team
Chromotography chrome system pump 2 is
6/8/2018 8:48:03 System malfunctioning. S.Nagoor 6/8/2018 8:46:00 Rectified Team Team
QC- Chemical,
6/12/2018 18:15:13 Spinwin Spin is Not working arun 6/12/2018 18:15:00 Rectified tempararely - new ordered chakra chakra
chromatography outlet ph and conductivity showing
6/13/2018 10:35:18 system out of range sivanesh 6/13/2018 10:35:00 Calibrated both,working fine Karthik Karthik
 Name of the
Breakdown person raising the Contact person from Severity of the
Timestamp equipment/Area Give brief details of the issue request Date of reporting Current status of the issue Engineering problem Closed by Remarks
[DYNA] 250 liter
-01 batch report not
generating , pls In scada system Exell report not
6/25/2018 10:41:21 rectify generating, pls rectify ASAP. ANANDH 6/25/2018 10:41:00 Awaiting Clearance Karthik
Temperature of microbiology lab is
more than 28 degrees C. It is
Microbiology lab supposed to be 22 +/- 3 degree C.
6/25/2018 13:50:23 temperature Amar Anand 6/25/2018 13:45:00 Rectified Chakra/Irshad Chakra/Irshad
WATER FLOW
6/27/2018 3:11:55 METER Without any flow its showing values. SUDHARSAN.P 6/27/2018 3:12:00 Found no issues Karhik Karhik
BOD Incubator-
BPM/MB/BDI/01 /
Incubation area Set temperature 32.5 is not
6/27/2018 10:35:48 Microbiology maintaining. Divya 6/27/2018 10:35:00 Rectified Karhik Karhik
Media vessels In fermentation area media vessels
lamp not working lamp not glowing pls rectify before
pls rectify next batch.

Old 5kl PU tubes to Old 5kl utility lines ADV PU tubes to

6/27/2018 15:35:57 be change be change. ANANDH 6/27/2018 15:36:00 lamps fixed , PU tubes replaced Karthik Karthik
At downstream all
mobile vessels
sample valve
leakage observed In downstream process area mobile
pls rectify. vessels sample valve leakage
observed pls rectify
And holding vessel
PU tubes to be We found holding vessels PU tubes Holding veseel PU tubes replaced, Mobile vessel
6/27/2018 15:40:07 change. puncher so pls change with new one ANANDH 6/27/2018 15:38:00 Sample valve didn't observed any leak Karthik Karthik
Upstream corridor Upstream corridor one CFL light not
one CFL light not glowing [near CIP station entrance]
7/16/2018 9:45:12 glowing pls rectify pls rectify ANANDH 7/16/2018 9:45:00 fixed Danesh Danesh
Steam header line and the
Steam leakage thermosyphon steam inlet and level
observed at new drain line both valve leakage
7/16/2018 9:50:16 250liter - 02 vessel observed pls rectify ANANDH 7/16/2018 9:48:00 Rectified Bogesh Bogesh
Media vessel 01 FRL and NRV not
working . please rectify.
For feed transfer line suport need,
line stand on only clamps suport due
that we are facing feed line clamps
Media vessels leak coming and valve also getting
7/18/2018 10:20:50 01&02 disturb. ANANDH 7/18/2018 10:20:00 Fixed Karthik Karthik
Production
Upstream and In upstream area, near media vessel
downstream areas PUW Station PUW02 valve, near old
PUW line manual 5 KL PUW Station PUW01 valve
diaphragms and downstream wash area PUW
7/30/2018 2:23:44 valve's. valves problem , please rectify. Krishna jasti 7/30/2018 2:22:00 Rectified Veeresh Veeresh/Pramod
The water inlet valve in autoclave is
broken due to continuous usage and
7/30/2018 14:59:09 Autoclave room needs to be replaced with new one. Amar 7/30/2018 14:59:00 Fixed pramod Pramod
Upstream
fermentation area
[BPM] all PuW Puw flow not coming properly at
valve service to be upstream fermentation area kindly
8/1/2018 18:43:20 done rectify ASAP... Anandh 8/1/2018 18:43:00 Done Veeresh Veeresh/Pramod
Near new 250liter New 250liter Steam header line
steam header line [flange] leakage found pls rectify the
8/1/2018 19:13:52 leakage is there issue Anandh 8/1/2018 19:13:00 fixed Dinesh Dinesh/Danesh
Production
quarantine
refrigerator
temperature not
maintaining at BPM/PD/RFG/01 quarantine
range pls find the refrigerator temperature not
problem and maintaining at range pls rectify the
8/7/2018 8:00:32 rectify.. issues Anandh 8/7/2018 7:58:00 Rectified Karthik Karthik
Purified water pipe
line (PUW -14) Purified water pipe line(PUW -14)
outlet valve outlet valve its not closing properly,
8/24/2018 14:06:05 problem and rectify the issue. Sarathkumar.m 8/24/2018 14:04:00 fixed Dinesh Dinesh
9/3/2018 17:03:18 Lyophilizer Temperature sensor is not working Sivanesh 9/3/2018 17:10:00 fixed Veeresh
9/4/2018 16:32:19 Lyophilizer Temperature sensor is not working Sivanesh 9/3/2018 17:10:00 fixed Veeresh
Ammonia clyinder Ammonia clyinder trolley bottom
trolley painting to looks full of rust pls plan for painting
9/4/2018 16:34:36 be done to avoid any physical damage Anandh 9/4/2018 16:34:00 Will be done ASAP Irshad
The door hinge of the documentation
Documentation cupboard is loosened and come
9/19/2018 10:13:55 room cupboard apart Amar 9/19/2018 10:14:00 Completed pramod Pramod
Harvest vessel -01 jacket chilled
water circulation actuated valve
passing is there to be rectified (inlet
9/24/2018 17:28:24 Harvest vessel -01 and outlet) sivanesh 9/24/2018 17:27:00 Completed chakra chakra
Harvest vessel -02 jacket chilled
water circulation actuated valve
9/24/2018 17:29:28 Harvest vessel -02 passing is there to be rectified (inlet) sivanesh 9/24/2018 17:28:00 Completed chakra chakra
Old 5kl instrumentation air line tubes
and connectors need to change with
new one (observed - leakage and
9/24/2018 17:30:43 old 5kl tank tubes getting break during process) sivanesh 9/24/2018 17:30:00 Completed Chakra chakra
Holding Vessel s (01, 02, and 03)
Holding Vessel s jacket actuated valves PU tubes to Leaks rectified, once tubes get damage will be
9/24/2018 17:31:40 (01, 02, and 03) be replaced with new one sivanesh 9/24/2018 17:30:00 replaced with new Karthik Karthik
Lyophilizer temparature sensor need
9/24/2018 17:32:56 Lyophilizer to fix. sivanesh09 9/24/2018 17:35:00 Alternate sensor fixed , OEM- sensor yet to receive Karthik
Media vessel 01 airline FRL cum
NRV not working properly please
9/24/2018 17:33:43 Media vessel 01 rectify ASAP sivanesh 9/24/2018 17:36:00 Cleaned Danesh Danesh
Near Old 5KL chilled water / cooling
water supply (header line) inlet and
fermentation area outlet lot of ants coming through
9/24/2018 17:38:17 wall, please close the issues. sivanesh 9/24/2018 17:37:00 Completed irshad irshad
QC Chemical area bulbs are not
9/27/2018 12:20:54 bulb not Working working. Sarathkumar.m 9/27/2018 12:17:00 Fixed Danesh Danesh
QC instrumentation area bulbs are
10/31/2018 7:29:39 bulb not Working not working. sarathkumar.m 10/31/2018 7:29:00 Fixed Danesh/Pramod Danesh/Pramod
Quality control Main Door properly
10/31/2018 7:32:44 Qc Door issue . not working Sarathkumar.M 10/31/2018 7:32:00 Fixed Danesh/Pramod Danesh/Pramod
Quality control, Quality control, Pestop bulbs are not
10/31/2018 7:34:35 Pestop working. Sarathkumar.M 10/31/2018 7:34:00 Rectified Danesh/Pramod Danesh/Pramod
5000 Liter
fermenter -02,
Temperature
sensors 111&112
not showing their In new 5kl following temperature
values (BPM- sensors 111 & 112 are not showing
upstream their respective values, pls rectify the
11/1/2018 3:32:41 fermentation area) issues ASAP ANANDH 11/1/2018 3:30:00 Rectified karthik Karthik
Temperature is out of limit in all the
11/9/2018 9:03:10 Microbiology area rooms Hanisha 11/9/2018 9:00:00 Rectified chakra Chakra
Steam utility line behind new 250L 1
1/25/2019 15:51:22 Upstream leakage Sathish 1/25/2019 15:50:00
Steam leakage in 2" TC clamp near
1/25/2019 15:52:29 5000L fermenter 2 thermosyphon Sathish 1/25/2019 15:52:00
1/25/2019 15:53:22 Media vessel 1 & 2 3 nos of diaphragm valves leakage Sathish 1/25/2019 15:53:00