Name of Drug Action Mechanism of Indications Adverse Effect Contraindications Nursing

Action Responsibilities
Brand name: Osmotic Increases osmotic  Mannitol has  Masking or  Established  Check
Osmitrol Diuretic pressure of approval for worsening anuria due to doctor’s
plasma in the reduction dehydration renal disease order
Generic name: glomerular of intracranial as it causes  Pulmonary  Check
Mannitol filtrate, inhibiting pressure and diuresis edema or cardiac
tubular brain mass.  Precipitate severe function as
Dose: reabsorption of  Mannitol is heart failure pulmonary the flid shits
84g of Mannitol water and approved to due to the congestion can
for 30-60 min, IV, electrolytes reduce rapid fluid  Severe precipitate
Q6 as ordered icluding sodium intraocular shifts as water dehydration heart
and potassium. pressure if this enters the  Progressive failure
These actions is not intravascular heart failure  Check
enhance water achievable by compartment  Known laboratory
flow from various other means.  Cause or mannitol results
tissues and  Mannitol can worsen hypersensitivity  Administer
ultimately promote electrolyte  Renal damage Mannitol at
decrease diuresis for abnormalities caused by the rifht
intracranial and acute renal due to the mannitol time and
intraocular failure to shift of free dose
pressures. prevent or water into the  Monitor
treat the intravascular Urine
oliguric phase space. output
before Electrolyte  Check if
irreversible abnormalities presence of
damage. may include side effects
 Mannitol can but are not of
also promote limited to medication
diuresis to hyponatremia,
promote the hypokalemia,
excretion of and
toxic hypocalcemia.
substances,  Precipitate
materials, and into crystals at
metabolites. low
temperatures,
which can
cause vascular
 and end-organ
damage
 Worsen
cerebral
edema.
DRUG TABULATION