DAVAO DOCTORS CRITERIA:

COLLEGE
General Malvar St., Davao
City
Nursing Program

DRUG STUDY
 Content and organization 40%
Analysis 40%
Neatness and 10%
promptness
Reference 10%
TOTAL 100%

Name of Patient: Dimaguiba, Adelaine Chantal Date of Admission: 08/15/2022 Room: 457
Age: 25 y.o Sex: Female Civil Status: Married Attending Physician: Dr. Elmer Chua

CLASSIFICATION / NURSING
DRUG NAME INDICATION CONTRAINDICATIONS ADVERSE EFFECTS
MECHANISM OF RESPONSIBILITY
ACTION
BRAND NAME/s: DRUG CLASS:  Enoxaparin  Ask the patient if
 Known hypersensitivity to
 Lovenox  Anticoagulants works  Bleeding gums. he/she is allergic
enoxaparin (urticaria,
by blocking a  Coughing up to this medication
anaphylactic reactions) or
GENERIC: Mechanism of Action: protein in blood.  Monitor the patient
any heparin products
 Enoxaparin  Enoxaparin binds to your body  Difficulty with for signs and
 Active major bleeding
sodium for antithrombin III, a that causes breathing or symptoms of
such as gastrointestinal
injection serine protease clotting. This swallowing. unexplained
bleed
inhibitor, forming a keeps blood  Headache. bleeding
 History of heparin-
DOSAGE: complex that clots from  Increased  Monitor platelet
induced
 40mg a day irreversibly inactivates forming. If menstrual flow or count because it
thrombocytopenia within
factor Xa, which is you have a vaginal bleeding. may cause
the past 100 days
ROUTE: frequently used to blood clot, it  Nosebleeds. thrombocytopenia
 Active gastric or duodenal
 Subcutaneous monitor anticoagulation will stop it  Paralysis. (platelet count is
ulcers
 Intravenous in the clinical from getting  Prolonged too low)
 Hemorrhagic cerebrovasc
setting.8 Following worse while bleeding from  Provide health
ular accident
FREQUENCY: factor Xa inactivation, your body cuts. teaching
 Severe uncontrolled
st
 1 dose should enoxaparin is released breaks down hypertension 
be given 2hrs and binds to other anti- the clot on its  Hepatic disease
before surgery thrombin molecules. own  Hemophilia 
(following doses Factor IIa (thrombin) is
 Deep venous  Thrombocytopenia of
should be given directly inhibited by
thrombosis platelet count less than
at the same enoxaparin, however
(DVT) 50 x 103
time each day) with less potency than
treatment  Caution is necessary if
unfractionated heparin
 Deep venous the patient has a spinal
(UFH). 6 Due to the
thrombosis catheter. Pregnant
cascade of effects
(DVT) patients with mechanical
resulting from
prophylaxis heart valves, elderly
enoxaparin binding,
 Treatment for patients, patients with
thrombin is unable to
weight less than 45 kg in
 convert fibrinogen to pulmonary a female patient or under
fibrin and form a clot, embolism 57 kg in male patients,
preventing (PE) acute endocarditis or
thromboembolic  Primary acute pericarditis also
events. prevention of require caution when
venous administering enoxaparin.
thromboembo
lism (VTE)
 Treatment for
prosthetic val
ve thrombosis
in pregnancy

REFERENCES:

NIH (2022). Platelet Disorders. Thrombocytopenia. https://www.nhlbi.nih.gov/health/thrombocytopenia#:~:text=Thrombocytopenia%20is%20a%20condition%20that,is

%20called%20a%20blood%20clot.
Nursingcrib (2007). Enoxaparin. Nursing implications. https://nursingcrib.com/drug-guides/enoxaparin/#:~:text=NURSING%20IMPLICATIONS&text=Monitor%20platelet
%20count%20closely.,or%20symptom%20of%20unexplained%20bleeding.
RxList (2021). Enoxaparin. What is enoxaparin and how does it work? https://www.rxlist.com/consumer_enoxaparin_lovenox/drugs-condition.htm
DRUGBANK Online (2005). Enoxaparin. Pharmacology. https://go.drugbank.com/drugs/DB01225