Drug Study (Concept Map)

LEGEND:

Drug Indication Nursing

Intervention

Drug Mechanism of Patient Teaching

Classification Action

Generic Name
(Brand Name) Side Effects
 Chemotherapeutic
Drugs

Antineoplastics;
Alkylating Agent Podophyllotoxin Derivatives

May cross-link Cisplatin Etoposide It works

strands of cellular (Platinol) (VePesid) by inhibiting or
DNA and interfere altering DNA
with RNA replication, induces
transcription, causing G2-phase arrest &
an imbalance growth preferentially kills
that leads to cell Lung Cancer: Small It is used in combination
with chemotherapies to cells in G2 & late S
death. Cell Lung Cancer or phases
treat small cell lung
Oat cell lung cancer cancer

 Ototoxicity  Nausea &Vomiting Leukopenia Hepatotoxicity  Thrombocytopenia

 Blood test  Neutropenia
abnormalities (low  Abdominal Pain
magnesium, low  Mucositis
calcium, low  Arrhythmias
\
potassium)  Hypotension
 Encephalopathy  Alopecia
 Nephrotoxicity
 Seizures
 Administer as prescribed
 Monitor infusion site; stop
infusion immediately and
notify prescriber if
extravasation occurs.
Don't flush the line.
 Monitor infusion site; stop
infusion immediately if
extravasation occur
 Monitor CBC, electrolyte
levels
 Monitor for signs of
ototoxicity
 To detect hearing loss,
obtain audiometry tests
before initial
0 and
subsequent doses
 Immediately give
epinephrine,
corticosteroids, or
antihistamines for
anaphylactic reactions.
 Monitor intake and
 Assess for signs of
output  Monitor vital signs
 Perform proper hepatotoxicity
 Administer anti-  Assess patient’s
handwashing  Stop medication
emetics routinely tolerance of pain.
technique when patient’s
every 4-6 hrs.  Monitor patient’s
 Put patient in reverse condition becomes
 Withhold foods mouth for any signs of
isolation if patient worst
and fluids 4-6 hrs.
WBC drops  Monitor patient’s ulcerations
before the
 Limit visitors liver  Monitor for any signs
chemotherapy
 Monitor temperature function regularly of toxicity
 Provide patient
q4  Provide supportive  Encourage patient to
with bland food in
 Assess for signs of therapy drink plenty of fluids
small amount after
respiratory infections and suck on sugarless
treatment
 Monitor lab result
 Provide cognitive hard candy.
especially leukocytes
distraction  Monitor laboratory
and neutrophils
results such as CBC
 Avoid IM injection if
platelet count is below
50,000mm/3
 Administer
epinephrine if
anaphylactic reaction
occurs.
 - Teach patient -Tell patient to - Advise patient to -Teach patient
-Advise patient to
to report all report all signs avoid taking any regarding the signs
report any sign of
adverse adverse reaction OTC drugs such of
bleeding (easy
reactions, and watch out for as aspirins -Inform patient that
bruising, nosebleeds,
including signs of infections - Tell patient to hair loss is just
bleeding gums, tarry
nausea and -Advise patient to avoid taking temporary
stools). It is advised
vomiting watch out for alcoholic drinks -Instruct patient to
to tell patient to take
- Advise patient signs and avoid using hard
temperature daily.
to suck ice chip symptoms of bristle toothbrush
-Tell patient to when feeling infection (fever, -Inform patient that
immediately report nauseous sore throat, frequent BP is
ringing in the ears or - Advise patient fatigue) needed during IV
numbness in hands to avoid eating -Instruct patient to administration
or feet. greasy, fatty avoid crowded -Advise patient to
-Instruct patient to and strong places avoid taking
avoid OTC products smelling foods aspirins
containing aspirin.
-Tell patient to report
any signs of pain in
insertion site.