Prescribe Drug Classification and Indication Side Effect or Special Precaution Nursing Responsibility

Mechanism of Action Adverse Reaction

Dosage, Route, and
ILOILODOCTORS COLLEGE
Frequency, Contraindication
Timing COLLEGE OF NURSING
WEST AVENUE, MOLO, ILOILO CITY
Generic Name: Classification: Indication: Common side NOTE: Aluminum Check the doctor’s order.
NAME: RUBY JANE LAQUIHON BSN 4-D reacts with
GROUP: 3
Carboplatin Antineoplastic/ Carboplatin effects of Observe the 10 rights of
carboplatin, USP
CLINICAL
Injection INSTRUCTOR: CELESTE
Alkylating DESLATE injection is giving medication.
carboplatin include: causing precipitate
indicated for the formation and loss of
Brand Name: Mechanism of Action:  nausea, Observe sign of adverse
initial treatment of potency, therefore,
 vomiting, reaction
Carboplatin Carboplatin advanced ovarian needles or
carcinoma in  numbness and
450mg predominantly acts by intravenous sets Advise patient to guard
established tingling of
attaching alkyl groups containing aluminum
Dosage: 450 mg combination with extremities, against infection (frequent
to the nucleotides, parts that may come
Route: leading to the formation other approved  ear infection, in contact with the hand washing, etc.), and to
of monoadducts, and chemotherapeutic  pain, drug must not be avoid crowds and contact
Intravenous agents. One
DNA fragmenting when  weakness, used for the with persons with contagious
Infusion
(injection) repair enzymes attempt established  allergic preparation or
combination diseases.
to correct the error. reactions, and administration of
This agent is regimen consists of carboplatin injection.
carboplatin  hair loss. Monitor signs of ototoxicity
characterized by its
Frequency and ability to generate injection and Unopened vials of such as hearing loss, tinnitus,
cyclophosphamide. Adverse Reaction: carboplatin injection
timing: lesions in DNA through disturbed balance, and
the formation of Carboplatin are stable to the date
Every 4 weeks injection is  bleeding and indicated on the vertigo. Report these signs to
adducts with platinum,
for 6 cycles indicated for the reduced blood package when stored the physician.
thereby inhibiting
replication and palliative treatment cells, at 20°-25° C (68°t o
of patients with 77° F) and PROTECT Monitor signs of leukopenia
transcription and including
ovarian carcinoma FROM LIGHT (fever, sore throat, signs of
leading to cell death reduced red
recurrent after prior infection), thrombocytopenia
blood Peripheral blood (bruising, nose bleeds,
chemotherapy,
including patients cells (anemia counts should be bleeding gums), or unusual
who have been ) and platelets frequently monitored weakness and fatigue that
previously treated (needed for during carboplatin might be due to anemia or
with cisplatin. injection treatment other blood dyscrasias.
proper blood
and, when
clotting); Guard against falls and 1
Contraindication: appropriate, until
 unusual recovery is trauma (hip fractures, head
Carboplatin is bruising or achieved. injury). Implement fall
contraindicated bleeding, prevention strategies,
 Prescribe Drug Classification and Indication Side Effect or Special Precaution Nursing Responsibility
Mechanism of Action Adverse Reaction
Dosage, Route, and
ILOILODOCTORS COLLEGE
Frequency, Contraindication
Timing COLLEGE OF NURSING
WEST AVENUE, MOLO, ILOILO CITY
Generic Name: Classification: Indication: Female patients Check the doctor’s order.
NAME: RUBY JANE LAQUIHON BSN 4-D Common side
Docetaxel should use effective
GROUP: 3 Antineoplastics/ Docetaxel is effects of Taxotere Observe the 10 rights of
birth control during
CLINICAL
Brand Name: INSTRUCTOR: CELESTE
Antimicrotubular DESLATE indicated as a giving medication.
include: treatment with this
Taxotere Taxanes single agent for the medicine and for 2
treatment of locally Observe sign of adverse
Dosage: Mechanism of Action:  injection site months after the last reaction
advanced or dose. Male patients
metastatic breast reactions
Adult: 10mg/mL Docetaxel is an who have female Advise patients that periodic
cancer after (pain,
(2mL, 8mL, 16 antineoplastic agent partners should use assessment of their blood
mL vials) that acts by disrupting chemotherapy redness, or effective birth count will be performed to
the microtubular failure. It is also swelling), control during detect neutropenia,
Route: network in cells that is indicated as a  nausea, treatment with this thrombocytopenia, and/ or
Intravenous essential for mitotic single agent for medicine and for 4 anemia.
 vomiting,
Infusion and interphase cellular locally advanced or months after the last
 diarrhea,
(injection) functions. Docetaxel metastatic non- dose. Monitor IV injection site for
small cell lung  constipation,
Frequency and binds to free tubulin pain, swelling, and
cancer (NSCLC)  loss of Docetaxel can
timing: 1 hour and promotes the
appetite, inflammation. Report
immediately assembly of tubulin into after platinum temporarily lower the
stable microtubules therapy failure. For  feeling weak number of white prolonged or excessive
followed by the treatment of blood cells in your
while simultaneously or tired, injection site reactions to the
cisplatin 75 metastatic blood, increasing the
inhibiting their  muscle pain, physician.
mg/m2 over 30-
60 minutes disassembly. This leads castration-resistant  joint pain,
chance of getting an
to the production of prostate cancer, infection. It can also
every 3 weeks docetaxel is  missed lower the number of Assess any muscle or joint
microtubule bundles
menstrual pain to rule out
without normal function indicated with platelets, which are
prednisone periods, necessary for proper musculoskeletal pathology;
and to the stabilization
of microtubules, which  temporary blood clotting.
Contraindication: that is, try to determine if
results in the inhibition hair loss, or
Be careful when pain is drug-induced rather
of mitosis in cells. Docetaxel is  fingernail or
using a regular than caused by anatomic or
Docetaxel’s binding to contraindicated in toenail chang toothbrush, dental
microtubules does not patients who have a biomechanical problems.
es. floss, or toothpick.
alter the number of history of severe Your medical doctor, 2
protofilaments in the hypersensitivity Adverse Reaction: Assess any breathing
dentist, or nurse may
bound microtubules, a reactions to recommend other problems, bronchospasm, or
feature which differs docetaxel or any of ways to clean your
Serious eye signs of pulmonary edema,
 ILOILO DOCTORS COLLEGE
COLLEGE OF NURSING
WEST AVENUE, MOLO, ILOILO CITY

NAME: RUBY JANE LAQUIHON BSN 4-D

GROUP: 3
CLINICAL INSTRUCTOR: CELESTE DESLATE

3
 Prescribe Drug Classification and Indication Side Effect or Special Precaution Nursing Responsibility
Mechanism of Action Adverse Reaction
Dosage, Route, and
ILOILO DOCTORS COLLEGE
Frequency, Contraindication
Timing COLLEGE OF NURSING
WEST AVENUE, MOLO, ILOILO CITY
Generic Name: Classification: Indication:  Caution in Check the doctor’s order.
NAME: RUBY JANE LAQUIHON BSN 4-D Common side
GROUP: 3 hepatic/renal
Dacarbazine Antineoplastic/ effects of Observe the 10 rights of
CLINICAL INSTRUCTOR: CELESTE DESLATE For the treatment of
Alkylating impairment; giving medication.
Brand Name: Dacarbazine monitor for
metastatic
Dtic- Dome Mechanism of Action: malignant include: toxicity. Observe sign of adverse
melanoma. In reaction
Dosage: Exert cytotoxic effects  May cause
addition,  nausea severe pain &
via its action as an Instruct patient to guard
alkylating agent. Other dacarbazine is also  vomiting
Adult and burning at
indicated for  loss of against infection (frequent
pediatric dosage theories include DNA injection site &
synthesis inhibition by Hodgkin's disease appetite hand washing, etc.), and
as a secondary-line along vein; to
Powder for its action as a purine  diarrhea to avoid crowds and
therapy when used alleviate, may
injection analog, and interaction  skin rash, or contact with persons with
in combination with increase
with SH groups.  flushing
other antineoplastic diluent, reduce contagious diseases.
 100mg Dacarbazine is not cell
agents. (numbness, infusion rate &
cycle-phase specific.
 200mg warmth, Advise patient about the
Contraindication: apply cold
redness, or compresses. likelihood of GI reactions
Route:
tingly feeling  Risk of such as nausea, vomiting,
Intravenous  Hypersensitivi
Infusion in the face). potentially diarrhea, and loss of
ty
(injection)  Breastfeeding fatal appetite. Instruct patient
Adverse Reaction:
 Severe anemi hepatocellular to report severe or
a,  Hives necrosis prolonged GI problems.
Frequency and severe throm  Difficulty  Avoid
timing: bocytopenia breathing, pregnancy. Advise patient that hair
 Swelling of loss and other skin
150 mg/m² the face, reactions (rash, pruritus)
Intravenous lips, . are likely. Report severe
once a day for 5 tongue, or
or unexpected skin
days, repeat throat,
reactions to the physician. 4
every 4 weeks  Fever,
OR  Tiredness,
Causes photosensitivity;
 Mouth