Features Function

most Etiology
Light microscopy Immuno Electron
abnormaliti
Treatment
orescence Microscopy
affected es/ signs
Condition

Minimal GN Children Idiopathic Negative Effacement Lose of negative Responds well to

charge on GBM
NSAID Normal of foot Albumin leaves steroids
Hodgkin process circulation

Membranous Adults Idiopathic Thick glomerular IgG Immune Autoantibody to Poor response to
Spikes and intrinsic glomerular
Gn Caucasian SLE basement complex steroids
deposition domes protein - podocyte

Hep B membrane and gbm injury

( subepithelial)
Adults High serum Mesangium Linear staining Microalbum ACE inhibitors
Thickened inuria
Type I glucose -> hyaline sclerosis - KW IgG along
Diabetic GBM
Type II arteriosclerosis nodules GBM
Amyloid deposits in
Amyloid p
Chemo
Amyloid mesangium and arteriole Proteinuria Stem cell transplant
immunohistoche
deposits in
Green birefringence of
mistry - brillary - HTN
Amyloidosis Congo red stain under
appearance ARF
mesangium polarizing microscopy

Adults Focal segmental Effacement of

Idiopathic IgM or C3 non Proteinuria
sclerosis foot processes
Hispanics speci c HTN Poor response to
FSG HIV Collagen deposits
African in capillaries trapping Hematuria steroids
Heroin
American (no deposition)
Group A beta Hypercellular IgG and C3 Subepithelial
Acute post Children hemolytic in amed ( diffuse Lumpy, bumpy , hump, Hematuria
ame like Oliguria Antibiotics -
Infectious streptococcal proliferative ) Immune
infection skin deposits HTN Supportive treatment
glomeruli complex
and throat deposition Peri edema
Most common Mucosal infection
Hypercellular ACEi, omega 3
worldwide— Mesangial IgA Mesangial Hematuria
IgA Chronic liver disease mesangium Immunosuppressant
presents Psoriasis, IBD, deposits IgA deposits RBC casts
Nephropathy s
during
HIV Statins
childhood

Children Type 1:HBV Double contours Mesangial IgG Poor response to

MPGN New Proteinuria
Young- HCV of BM (tram and C3 steroids
basement Hematuria
adults Type 2: C3 tacks), deposits and
membrane HTN
nephritic factor subendothelial between tram
deposits tracks Low C3
Mesangial, Low
Young Antibodies directed Proliferative or Full house subendothelial Steroids
against wide complement
LUPUS females membranous GN deposits could subepithelial , levels Cyclosporine
variety of cellular
components Interstitial be anywhere tbm deposits Anti dsDNA
in ammation ANA
Antibodies directed Proliferative GN
Goodpasture against antigens Rapidly

Syndrome Young with crescents, deteriorating renal

Plasmapheresis
( collagen type 4) Linear GBM None - little function
males in glomerular and necrosis and Pneumonitis Cyclophosphamide
IgG and C3 to see Hemoptysis
pulmonary alveolar brin collapsed Cough
BM glomerulus deposits Hematuria
Antibodies to
Fifth or Fever
Pauci-immune lysosomal
Crescents Minimal or no Steroids
sixth enzymes of dyspnea
Vasculitides immune Negative Cyclophosphamide
decade of neutrophils and arthralgia
monocytes Granulomatous deposits
age weight loss
( ANCA) in ammation sinusitis
epistaxis
hemoptysis