Name of the Indication Mechanism of Side effects Adverse Effects Contra- Nursing Responsibilities

drug action indications

Generic Name: Relief of pain aspirin-like drug that Stop using mefenamic CNS: dizziness, - contraindicated
hypersensitivity to other
Before
including muscular, has analgesic, acid if you headache, - Assess pt's pain before
rheumatic, NSAIDs
antipyretic and anti- feel/have/experienced: nervousness, tremors in pts drug or therapy: location, duration,
Mefenamic Acid traumatic, dental, inflammatory frequency, precipitating
- contraindicated in those
post-operative and
activities. These - shortness of breath CV: congestive heart who have experienced and aggravating factors
postpartum, pain, asthma, urticaria or allergic- - Tell pt to report history of
headache, migraine, activities appear to be - swelling or rapid failure, hypertension,
type reactions after taking allergic reactions to
fever and due to its ability weight gain tachycardia, sycope
Brand Name: aspirin NSAIDs before starting
dysmenorrhea. inhibit cyclooxygenase - nausea, diarrhea, flu- - contraindicated in pts with
GI: gas pain, therapy
& also antagonize like symptoms (fever, acute active ulceration or
- Prepare food to intake with
certain effects of swollen glands, muscle diarrhea/ chronic inflammation of
Ponstan, ponstel either upper or lower GI drug
prostaglandins. aches, severe constipation, - Assess if the pt has taken
tract
weakness) vomiting, dyspepsia, drug that may decrease the
Pharmacokinetics: - skin rash peptic ulceration, Precaution: use cautiously in medication's effectiveness
- signs of stomach nausea pts with history of ulcers or - Inform patient need and
Dosage, Route: Absorption: well bleeding GI bleeding. asthma, importance of the drug to
absorbed - liver problems Metabolic: weight epilepsy, kidney or liver him/her
changes disease
- kidney problems
500mg Distribution: wide - low red blood cells Drug Interaction: Drug-drug,
During
QD PO - heart burn, stomach Respiratory: ACE inhibitors: May - Administer with food or
Metabolism: liver pain, gas, nausea, asthma, dyspnea decrease antihypertensive milk to decrease gastric
vomiting effects. Monitor BP. Aspirin: symptoms
Drug Excretion: kidneys - diarrhea, Skin: rash, alopecia May increase risk of ulcers. - Do not increase dose
(50%) liver (20%) photosensitivity, Diuretics: May reduce the without physician's order -
Classification: constipation natriuretic effect of
pruritus Administer drug with full
- dizziness furosemide and thiazides in
Half-life: 2-4 hours glass of water to enhance
some pts.
absorption
Analgesic, non- Urogenital: Cystitis, Methotrexate: May inhibit
- Do not crush, dissolve or
steroidal anti- Onset: unknown dysuria, hematuria, methotrexate accumulation
chew capsules/tablets -
Peak: 2-4 hours in rabbit kidney slices.
inflammatory interstitial nephritis, Caution in pts with history
Drug-herb: Dong quia, fever
Drug (NSAID) Duration: unknow oliguria/polyuria, few, garlic, ginger, horse of peptic ulceror Gl
renal failure chest nut, red clover: May bleeding, epilepsy or liver
increase risk in bleeding disease
Drug-lifestyle: long term - Observe 15 R's of drug
alcohol use, smoking: May administration
cause gastric irritation or
bleeding.
After
- Instruct pt not to take drug
for more than 7 days
- Advise pt to immediately
report persistence or failure
to relieve pain
- Tell pt to report occurrence
of drug induced adverse
reactions
- Teach pt that all NSAIDs,
including mefenamic acid,
may harm the liver
- Discuss in detail all aspects
of the drug therapy: reason
for taking the drug &
expected results