DRUG STUDY

Drug Name Classification and Indications and Side Effects and Adverse Special Precautions Nursing Responsibilities
Mechanism of Action Contraindications Effects
Generic Name: Classifications: Indications: *CNS: Headache, dizziness, Use cautiously in patients  Advice the patient to
somnolence, insomnia, that is pregnant, a lactating take the medicine as
Mefenamic acid NSAID *Relief of moderate pain fatigue, tiredness, dizziness, mother, patients with asthma, prescribed by the
when therapy will not tinnitus, ophthalmic effects. renal or hepatic impairment, Doctor while
Mechanism of Actions: exceed 1 week. peptic ulcer disease, GI explaining the possible
Trade/ Brand Name: *Treatment of primary *Dermatologic: Rash, bleeding, hypertension and side effects.
Mefenamic acid as an dysmenorrhea. pruritus, sweating, dry heart failure.  Inform patient about
Apo-Mefenamic (CAN), NSAID works by stopping mucous membranes, some side effects in
Ponstel the body’s production of a stomatitis. order to be aware and
substance that causes pain, avoid panic.
Dosage: fever and inflammation. Contraindications: *GI: Nausea, dyspepsia, GI  Monitor if patient have
pain, diarrhea, vomiting, hypersensitivity to the
500 mg *Contraindicated with constipation, flatulence, drug.
hypersensitivity to ulcers, GI bleed.  Assess patients who
Route: mefenamic acid, aspirin develop severe diarrhea
allergy and as a treatment *GU: Dysuria, Renal and vomiting for
Oral of perioperative pain with Impairment. dehydration and
coronary artery bypass electrolyte imbalance.
Frequency and Timing grafting. *Hematologic: Bleeding,  Monitor Lab tests of
platelet inhibition with higher patient: With long-term
q4h prn for pain doses, neutropenia, therapy (not
eosinophilia, leukopenia, recommended) obtain
pancytopenia, periodic complete
thrombocytopenia, blood counts, Hct and
granulocytopenia, aplastic Hgb, and kidney
anemia, decreased Hgb or function tests.
Hct, bone marrow depression,  Discontinue drug
menorrhagia. promptly if diarrhea,
dark stools,
hematemesis,
*Respiratory: Dyspnea, ecchymosis, epistaxis,
or rash occur and do
hemoptysis, pharyngitis,
not use again. Contact
bronchospasm, rhinitis.
physician.
  Notify physician if
*Other: Peripheral edema, persistent GI
anaphylactoid reactions to discomfort, sore throat,
anaphylactic shock. fever, or malaise occur
on patient.
 Instruct patient not to
drive or engage in
potentially hazardous
activities until response
to drug is known. It
may cause dizziness
and drowsiness.
 Monitor blood glucose
for loss of glycemic
control if diabetic.
Inform patient not to
breast feed while taking
this drug without
consulting physician.