DRUG NAME MECHANISM DOSAGE INDICATIONS CONTRAINDICATIONS ADVERSE REACTION NURSING RESPONSIBILTIES

OF ACTION
GENERIC NAME: 10 or 20 Atorvastatin is indicated  Hypersensitivit  Gastrointestinal  Stress that
Atorvastatin Atorvastatin is milligram for the treatment of y to symptoms such atorvastatin is an
a statin s orally several types of atorvastatin. as diarrhea adjunct to-
BRAND NAME: medication and once a dyslipidemias, including  Active liver  Cold symptoms  not a substitute for
Atorvaliq, a competitive day primary hyperlipidemia disease or such as a runny low-cholesterol
Caduet, inhibitor of the and mixed dyslipidemia unexplained or stuffy nose diet
Lipitor, enzyme HMG- in adults, transaminase  Joint pain
Lypqozet CoA (3- hypertriglyceridemia, elevation.  Insomnia  Tell patient to take
hydroxy-3- primary  Your doctor  Urinary tract drug at the same
methylglutaryl dysbetalipoproteinemia should not infection time each day to
coenzyme A) , homozygous familial prescribe this  Nausea maintain its effects
DRUG
reductase, hypercholesterolemia, medication if  Loss of appetite
CLASSIFICATION
which catalyzes and heterozygous you are a  Indigestion
: HMG-CoA
the conversion familial patient with symptoms such  Instruct patient to
reductase
of HMG-CoA to hypercholesterolemia in liver problems. as stomach take amassed dose
inhibitors
mevalonate, an adolescent patients  Women who discomfort or as soon as
early rate- with failed dietary are pregnant or pain  possible. If it’s
limiting step in modifications. breastfeeding  Increased almost time
cholesterol should not take transaminases  for his next dose,
biosynthesis.1, atorvastatin.  Muscle spasms he should skip the
8 Atorvastatin with or without missed dose.
acts primarily in pain
the liver, where  Musculoskeletal
decreased pain (pain that  Advise patient to
hepatic affects the notify prescriber
cholesterol muscles, immediately if he
concentrations ligaments, develops
stimulate the tendons bones, unexplained muscle
upregulation of land joints pain, tenderness,
hepatic low-  Muscle pain or
density  Limb pain weakness,especiall
lipoprotein  Mouth and y if accompanied
(LDL) receptors, throat pain byfatigue or fever
which increases  Chest pain
hepatic uptake (angina)
of LDL.
 Lightheadednes
Atorvastatin
s and fainting
also reduces
 DRUG NAME MECHANISM OF DOSAGE INDICATIONS CONTRAINDICATIONS ADVERSE NURSING
ACTION REACTION RESPONSIBILTIES
GENERIC NAME: Ivabradine Ivabradine is Ivabradine is FDA- Acute The most Before taking
Ivabradine
Very-Low-
lowers heart available as approved in the decompensated  Shortness common of ivabradine, tell
Density tablets to be United States for heart failure breath or other
adverse effects your doctor or
rate by
Lipoprotein- taken by mouth. use in patients breathing
include pharmacist if
BRAND NAME: selectively
Cholesterol with symptoms Clinically significant problems
bradycardia, you are allergic
Corlanor, inhibiting If
(VLDL-C), The initial dose due to stable hypotension  Muscle
atrial fibrillation, to it; or if you
Lancora, serumchannels
should be 5 mg, heart failure and weakness
high bloodor have any other
Procoralan triglycerides("funny losspressure,
of muscleand
twice a day. an ejection Sick sinus allergies. This
(TG) channels")
and in The dose can be fraction of 35% or syndrome, strength
phosphenes. product may
Intermediate
the heart in a adjusted after 2 less to reduce sinoatrial block, or Muscle ache contain inactive
DRUG Density
CLASSIFICATION:
concentratio weeks based on their risk of third-degree AV  Severe allergiccan
Ivabradine ingredients,
Lipoproteins
n-dependent the heart rate. hospital block (unless a reaction
cause which can cause
hyperpolarization-
(IDL), as wellmanner
as The maximum admission for (anaphylaxis)
functioning demand bradycardia, allergic reactions
activated cyclic
the numberwithout
of
nucleotide-gated dose is 7.5 mg, worsening heart pacemaker is  Stevens- sinus arrest, and or other
apolipoprotein twice a day. failure.[1][2][3] present) Johnson
heart block. problems. Talk
(HCN) channelB (apo affecting any
B) Patients with syndrome
Sinus node to your
blockers containing cardiac
other
conduction Patients on  Muscle
Clinically significant dysfunction, pharmacist for
particles, butionic defects or ivabradine bradycardia inflammation,
first- or second- more
increases High-channels
bradycardia can therapy should with or without
degree details.Before
Density(including pain
be initiated on 2.5 have a resting Severe hepatic atrioventricular using this
calcium or
Lipoprotein mg, twice a day. heart rate of at impairment block, bundle medication, tell
potassium).
Cholesterol The reduction in least 70 beats per branch block, your doctor or
(HDL-C).
Ivabradine heart rate minute and must Pacemaker ventricular pharmacist your
binds by depends on the be in normal sinus dependence (heart dyssynchrony, medical history,
entering and baseline heart rhythm. They rate maintained and or especially of: low
attaching to rate and the should also be on exclusively by the concomitant use blood pressure,
a site on the ivabradine dose. their maximum pacemaker) of other heart- liver problems,
channel pore tolerated beta- rate reducing other heart
from the blocker or have a Concomitant use of drugs increase problems (such
intracellular contraindication strong CYP3A4 the risk of as sick sinus
side and to beta-blocker inhibitors bradycardia. In syndrome, heart
use. the SHIFT trial, block,
disrupts If
symptomatic slow/irregular
ion current
In Europe, bradycardia heartbeat,
flow, which ivabradine is occurred in 5% pacemaker
prolongs indicated in the of patients use).This drug
diastolic treatment of taking may make you
depolarizatio heart failure and ivabradine dizzy or cause
n, lowering chronic stable compared to 1% vision changes.
heart rate. angina. in the placebo Alcohol or
The If group. marijuana
currents are Asymptomatic (cannabis) can
located in bradycardia make you more