Professional Documents
Culture Documents
many recipients still need to take some near future is the closed loop or artificial
insulin after a transplant, although their pancreas system, consisting of an insulin
insulin requirements are usually lower. pump, a continuous glucose monitor, and
Not everybody is suitable for a transplant, a communication link. The monitor sends
and the number that can be performed data to a small computer, which uses
is limited by the relatively small number an algorithm to instruct the pump to
of donor pancreases available. adjust your insulin dose according to your
blood glucose level. The system displays
New technology on your smartphone or smartwatch, and
Advances in technology are helping to you can also revert to manual control.
make diabetes management easier and
more precise. For example, smart pen
TAKING PART IN RESEARCH
devices (not yet available worldwide) store
Research may range from simply completing a questionnaire to
data that you can download later, which
something more involved, such as trying new therapies. Official
means that you can easily record dates,
research requires formal consent, so that you are fully informed
times, and amounts of your insulin doses,
and can withdraw at any time. If you are interested in participating,
carbohydrate intake, and blood glucose your diabetes healthcare professionals or diabetes organizations
levels. An advance that seems likely to will be able to provide up-to-date information.
become more widely available in the
Liver
Insulin
Islet
Recipient’s cells
Pancreas liver
tissue Liver
Blood vessel carries
Islet cells insulin from liver to
infused into body tissues
vein that
Tissue Separated, supplies liver
processed purified islet
Syringe
cells
and cannula
Hypoglycaemia
Commonly known as a “hypo”,
hypoglycaemia is when your blood
glucose level falls too low. It is often due
to a dose of insulin or insulin-stimulating
medication that is too high in relation to
your food intake. Being aware of factors
that trigger a hypo can help you to
prevent one.
What is hypoglycaemia?
In practical terms, a hypo means a blood glucose
level below 4 millimoles per litre (mmol/L). Hypos
occur when there is more insulin in your body than
you need at the time, typically because your insulin
or medication dose does not match your food intake
or level of activity. Hypos often cause recognizable
symptoms (see pp.64–65), although the blood
glucose level at which symptoms become noticeable
can vary from person to person, and symptoms may
be more pronounced in some people than others.
◁ Fitting in food
A busy lifestyle can make it difficult to eat regularly.
However, missing or delaying eating puts you at risk
of a hypo, so it is helpful to be aware of when to eat
and to set up reminders for yourself.
PREVENTING AND
ACTING ON HYPOS
● Keep checking your blood glucose several hours after
vigorous activity as delayed hypos can occur.
● If it helps to involve others, ask your family, friends, or
colleagues to remind you to check your blood glucose
and to eat snacks regularly.
● Keep glucose and carbohydrate snacks handy.
● If you have frequent hypos, talk to your health
professional about changing your medication type
or timing to better suit your routine.
Hypoglycaemia 63
Various factors may trigger a hypo; the more common ones blood glucose drops too low, because a very low level can
are detailed in this chart. It is important to try to prevent make you feel unwell, stop you thinking clearly, and even,
hypos and treat them promptly (see pp.66–67) before your in some situations, cause you to lose consciousness.
CAUSE PREVENTION
If you take insulin, an occasional hypo is to be If you have hypos frequently, you may need a lower
expected. You are also at risk of hypos if you take dose of insulin or medication. If you take insulin or
insulin-stimulating medications (see pp.58–59). other medication several times a day, it is important
Other diabetes medications taken on their own to identify which injection or tablet is responsible for
do not carry a significant hypo risk. the hypo and then adjust that dose.
Medication
dose
Injected insulin and insulin-stimulating medication If you use insulin or insulin-stimulating medication,
work over a number of hours, and if you do not eat you need to know whether it has a peak of action, and
during this period, you risk having a hypo. if so, when this is so that you can balance your insulin
dose or medication with carbohydrate-containing
foods. If you are unsure about the timing of food for
your particular insulin or medication regimen, talk
Food it through with your health professional.
intake
Initially, alcohol causes your blood glucose to rise but You can prevent an alcohol-induced or prolonged
then, over a period of hours, causes it to fall, putting you hypo by never drinking on an empty stomach and,
at risk of a hypo if you take insulin or insulin-stimulating if you drink more than 2–3 units of alcohol, by eating
medication. Hypos due to drinking are particularly extra carbohydrate to compensate. Checking your
dangerous and in some circumstances can be life- blood glucose after drinking (or asking somebody
threatening, because alcohol prevents your liver from to help you with this) is also important.
Alcohol releasing stored glucose efficiently.
Any sort of physical activity – including everyday You can prevent a hypo by reducing the dose of
tasks, such as housework or shopping – needs your insulin or insulin-stimulating medication before
energy, which is mainly obtained from glucose. any physical activity or by eating extra food before,
The more active you are, the more glucose you during, or after activity. Prolonged or strenuous activity
“burn” and the more your blood glucose falls. requires more careful planning (see pp.100–107).
Physical
activity
Stress usually makes your blood glucose rise Try to establish what effect stress has on your blood
due to the effects of the stress hormones adrenaline glucose. If you know that it lowers your blood glucose,
and cortisol. However, in some people or situations, you can compensate by eating extra food or reducing
stress may make your blood glucose fall because your dose of insulin or insulin-stimulating medication.
your body may use extra energy when you are
stressed, or you may not eat regularly.
Stress
Exposure to heat makes your blood circulate Checking your blood glucose before exposing yourself
more quickly, which means that insulin and insulin- to unusual heat will help you identify if you are close
stimulating medication work faster than usual. This, to a hypo and whether you need extra food to avoid
in turn, causes your blood glucose to fall. You may one. In similar situations in the future, you may need
find that you are prone to hypos in hot conditions, to reduce your dose of insulin or insulin-stimulating
even after a hot bath or sauna. medication or eat extra food.
Heat
64 Managing your blood glucose
Recognizing
hypoglycaemia
A low level of glucose in the blood – hypoglycaemia – is potentially serious
but recognizing the symptoms as soon as possible usually enables the
condition to be treated quickly and easily. The symptoms are more
pronounced in some people than others, and if you are not able to detect
your own symptoms, you may need to rely on people around you for help.
Early warning symptoms your blood glucose level will give you the
When your blood glucose first starts to fall, data to decide if any action is necessary.
you may experience early symptoms of a A fingerprick check gives a “snapshot”
hypo (see table, opposite), because your reading but does not reveal whether
body releases adrenaline in an attempt your blood glucose level is changing. In
to raise your blood glucose. You may not contrast, a continuous monitor or flash
have all or even any of these symptoms. monitor shows your glucose level and
It is also possible to experience early whether it is rising, falling, or constant.
symptoms due to any rapid fall in blood If you have symptoms and your test result
glucose – for example, from 15 millimoles is 4 mmol/L or lower, you should start to
per litre (mmol/L) to 7 mmol/L. Checking treat yourself immediately (see pp.66–67).
◁ Uncharacteristic
behaviour
A hypo can affect
the way you behave,
for example, by
making you anxious,
tearful, irritable, or
uncooperative.
Recognizing hypoglycaemia 65
Headache; difficulty in
concentrating; disorientation;
Anxiety Trembling
being uncooperative and/or
aggressive
Palpitations;
Dilated pupils Blurred vision
fast pulse
Tingling of Unsteady
Nausea
lips movements
Reduced awareness
These types of monitors display both your blood
glucose level and its direction. Some continuous
4.0 mmol/L
If a hypo causes unconsciousness, you will glucagon injection kit is not available or you
need to give the person a glucagon injection, have not been shown how to inject, you
if you have been trained how to do so. If a need to get emergency medical help.
Put the person in the recovery position: If you have a glucagon injection kit,
1 on their side, with their arm and upper 2 remove the seal on the glucagon bottle.
leg at right angles to their body, and their Uncap the needle, put it into the bottle, and
head tilted back to keep the airway clear. inject the water from the syringe into the bottle.
Rotate the bottle until all the Insert the needle at a right angle to the
3 glucagon has dissolved. Turn the 4 person’s thigh, buttock, or arm, and
bottle upside down and put the needle press the plunger to inject. Withdraw the
tip in the solution. Pull back the plunger needle, press a tissue/swab against the
to withdraw all the solution or the dose injection site, and keep the person in the
you have been prescribed. recovery position until they are conscious.
A blood glucose level that is too high is known as ● If you know you are going to eat more
carbohydrates than usual, adjust your
hyperglycaemia. It is the main effect of untreated insulin or medication, or be more active.
diabetes. Your diabetes treatment is aimed at ● Be aware of the effect of stress and other
hormonal changes on your blood glucose
reducing hyperglycaemia while also avoiding so you can predict when you need to
adjust your treatment.
hypoglycaemia (low blood glucose, see pp.62–63).
● Don’t stop taking your insulin or other
medication when you are ill, and monitor
your blood glucose frequently.
What is hyperglycaemia? ● Take your insulin or medication every day,
and adjust the dose when necessary.
This is the technical term for blood glucose levels above
about 7 millimoles per litre (mmol/L). Hyperglycaemia
may not only make you feel unwell in the short
▽ When you are ill
term, but also increases your risk of long-term Illness often causes your blood
complications. This is why a blood glucose glucose to rise. Keep taking your
level of 4–9 mmol/L is recommended, diabetes medication and monitor
depending on your age and the type of your blood glucose frequently so
diabetes you have (see p.30 and p.38). that you know if you need to adjust
your medication dosage or timing.
However, in daily life with diabetes, you
will sometimes experience periods
of hyperglycaemia, and taking action
to prevent them (see opposite) or limit
their length (see pp.70–71) will help
to keep you well.
Hyperglycaemia 69
A wide variety of factors may lead to hyperglycaemia. You can and relating the level to your circumstances at the
identify the specific cause of hyperglycaemic episodes that time, which can help you prevent further episodes
affect you by checking your blood glucose level regularly in the future.
CAUSE PREVENTION
Probably the most common causes of You can help to prevent hyperglycaemia by following
hyperglycaemia are an increase in the healthy eating guidelines (see pp.74–75), staying
amount you eat (especially carbohydrates) active (see pp.100–103), and paying attention to
or a decrease in physical activity, or a balancing your food intake and medication. If you
combination of both. Occasionally, an have type 2 diabetes that you manage with food and
increase in physical activity may cause activity but find that your blood glucose is raised
Food intake/ hyperglycaemia (see pp.104–105). frequently, you should talk with your health professional
physical because you may need to start taking medication to
activity manage your diabetes.
When you are ill, more glucose is released by the Frequent blood glucose monitoring when you
liver into your bloodstream. Increased amounts are ill enables you to quickly adjust your diabetes
of the stress hormones cortisol and adrenaline treatment to compensate for your raised blood
are also produced, which can interfere with glucose level (see pp.70–71), or get advice from
the action of insulin, also causing your blood your health professional.
glucose to rise.
Illness
Stress hormones can disrupt the action of insulin, If you find that stress or other hormonal changes
causing your blood glucose to rise. When you raise your blood glucose, increase the frequency
are stressed, you may also overeat or eat less of blood glucose monitoring (or start monitoring, if
healthy foods, which can also cause your blood you do not already do so) and, if your blood glucose is
glucose to rise. If you are a woman, you may raised, take action by adjusting your diabetes treatment
find that your blood glucose rises at certain (see pp.70–71). If your hyperglycaemic episodes are due
Stress/
stages of your menstrual cycle (particularly just to hormonal changes, it may be possible to reduce the
hormonal
before periods). Hormonal changes during the episodes by treating the underlying hormonal condition.
changes
menopause can also cause hyperglycaemia, Your health professional can help with this.
as can some hormonal disorders, such as
Cushing’s syndrome (abnormally high levels
of corticosteroid hormones).
If you have not taken your insulin or other Ensuring you take your insulin or other medication as
medication, your blood glucose rises. recommended is crucial to avoiding hyperglycaemia.
Sometimes, it may rise even if you have If you have been doing this but still experience frequent
taken your insulin or medication correctly hyperglycaemic episodes, your health professional may
but it is no longer working effectively. talk with you about, or advise changing to, a different
dose or type of insulin or medication.
Diabetes
medication
symptoms, including:
3+
• Nausea and vomiting.
• Abdominal pain. Severely raised: Ketone level of 2+ or more
Ketone level (+)
Healthy eating
Drinks
Physical activity
Healthy eating
The basic principles of healthy eating if
you have diabetes are no different to those
for anyone else. However, it’s good to be
familiar with the main food groups and
how to balance your food intake to be as
healthy as possible. Eating healthily is one
of the key factors in reducing the risk of
heart disease and other complications.
HEALTHY EATING
TIPS
● Limit the amount of ● Eat more high-fibre
table sugar and sugary foods, including fruit
foods you consume. and vegetables.
● Watch out for hidden ● Try to have homemade
carbohydrates, especially meals rather than
in fruit drinks. ready-made meals
several times a week.
● Eat regular meals that
contain some complex ● Reduce red meat in
carbohydrate. your everyday eating.
● Choose healthier ● Reduce your salt intake
carbohydrates such as to help prevent high
brown rice, chickpeas, blood pressure.
lentils, and vegetables. ● Keep your alcohol
● Cut down on fat, consumption within
especially saturated fats. the recommended limits.
Healthy eating 75
A balanced diet
◁ Food choices
You can achieve a balanced diet by eating a variety
Making healthy choices in what
you eat will help you manage
of foods from each of the main food groups:
your diabetes and keep you well proteins, carbohydrates, and fats. There are no strict
in the long term. recommendations about the proportion of each, but
there are general guidelines. In the UK *, these state
that starchy carbohydrates (such as grains, cereals,
potatoes, and bread) and fruit and vegetables should
make up the bulk of meals – about two-thirds of a
plate. Protein-rich foods, such as eggs, pulses, fish,
or lean meat, should form a smaller part of each meal.
You should aim to have at least five portions of fruit
and vegetables a day (one portion being 80 g) – an
apple, a handful of berries, or three tablespoons of
peas, for example. Fruit and vegetables are low in
calories and rich in vitamins and minerals, although
fruit does contain some natural sugar. Sugar, salt, and
saturated fat are ideally eaten only in small amounts.
FOOD GROUPS
There are three main food groups – carbohydrates (simple and complex),
fats, and protein. Individual foods may contain more than one of these
food types, although one component usually predominates.
These are rapidly absorbed and cause a sharp treat a hypo caused by too much insulin. Many
rise in blood glucose levels, but are useful to processed foods contain hidden sugars.
Fruits contain the fruit Milk and yoghurt: Fruit juice contains
sugar fructose. Berries cows’ milk (all types, fruit sugar (fructose),
have low levels, while unflavoured) contains which is rapidly
pineapple, mango, 5% lactose; yoghurts absorbed.
and melon are high may be sweetened with
in fructose. sugar or fruit purée.
These are broken down in the digestive are digested relatively slowly so do not
system into glucose, but unprocessed forms cause a dramatic rise in blood glucose.
Bread (including naan, Rice: brown and wild Pasta and couscous
pitta, and chappatis): rice are broken down are both wheat-based
wholegrain varieties more slowly than products. Wholewheat
are digested more white rice. pasta is broken down
slowly than refined more slowly than
types. ordinary pasta.
Managing your
carbohydrate intake
Carbohydrates have a significant impact
on your blood glucose level, so you need
to be aware of the carbohydrate content
of what you eat. Being aware of your
intake can help you in managing your
diabetes, whatever type it is. Monitoring
and limiting your carbohydrate intake can
be a good way to lose weight if you need
to, or to prevent or delay type 2 diabetes.
Foods with no carbohydrate do not tend
to affect blood glucose levels.
Carbohydrate counting (see p.82) is
an important method for matching the △ Reducing overall GI
amount of insulin you need to take. While The GI applies to a specific food eaten on its
carbohydrate content will have the most own. Eating a low GI food together with a high
one can reduce the overall GI.
effect on your blood glucose, considering
the glycaemic index (GI) of food can also
be useful – for example, if you are having Understanding glycaemic index (GI)
unexpected swings of blood glucose. The GI is a ranking of carbohydrate-
containing foods based on their effect
Low GI foods are not always a on blood glucose level. Foods that are
digested slowly have a low GI rating;
healthy choice. Peanuts, for quickly digested foods have a high rating
example, are high in fat. (see chart opposite). Eating more low-
and medium-GI foods can help you
balance your blood glucose level.
High-GI ◁ GI and blood glucose level
food Foods with a high GI raise blood Higher-GI foods tend to be those that
glucose dramatically within about are higher in refined sugar. These foods
half an hour. Foods with a low GI can cause spikes in your blood glucose
raise blood glucose to a much level. On the other hand, not all lower-GI
Blood glucose level